This book discusses the main approaches for mediastinal mass diagnosis and treatment, whose different aspects have been thoroughly treated by a multidisciplinary team of experts from different clinical fields.
Author: Renato Franco
Publisher: Humana Press
Tumors of the mediastinum are usually diagnosed in young patients, but they can develop at any age and form any tissue that exists in or passes through the chest cavity. The diagnosis and the accurate assessment of the mediastinum masses represents a challenge, given their clinical variability from asymptomatic to producing symptoms of cough, chest pain, and dyspnea. Mediastinal tumors encompass a wide range of various neoplasms. The localization of mediastinal masses is critical in the diagnosis: the anterior mediastinal masses are generally thymomas, teratomas, substernal thyroid/parathyroid tissue, or lymphomas; the middle mediastinum massess are typically pericardial and bronchogenic cysts; the posterior mediastinum masses are often neurogenic tumors and esophageal cysts. The wide variety of different entities demonstrates a heterogeneous spectrum of clinical and pathologic features, suggesting that a uniform “standard” management of these patients is not appropriate. In this context, the proposed book will provide a comprehensive review of the mediastinal tumors according to different sites of the diseases, including the masses of anterior, middle and posterior mediastinum. The handling of these tumors requires a multidisciplinary approach due to the complex anatomy of the mediastinum as well as the different clinical, radiographic, and prognostic features. This book has risen from the desire to provide to the specialists in the field an easy, updated and practical guidelines title to facilitate the clinical practice of mediastinic masses. This book will be a comprehensive guide to clinical best practices developed through the opinions of experts in the field.
This volume represents the premier work devoted solely to the complex myriad of mediastinal tumors. The contributors to the state-of-the-art text are clinical investigators of international renown.
Author: Douglas E. Wood
Primary mediastinal tumors are relatively rare. The relative incidence of these tumors indicates that neurogenic tumors are the most common tumor seen constituting 21 % of all cases, thymomas 19%, lymphomas 12.5%, germ cell tumors 10%, primary carcinomas 4.6%, mesenchymal tumors 6%, endocrine tumors 6%, cysts 18%. In adults, the majority of thyroid tumors, thymomas, mediastinal germ cell tumors and teratomas are located in the superior and anterior mediastinum. Of the neurogenic tumors 18% are located in the posterior mediastinum, and 50% of mediastinal lymphomas are in the middle mediastinum. In adults, the incidence of anterosuperior, middle and posterior mediastinal tumors is about 54%, 20% and 26% respectively. However, in children the posterior mediastinum contains 63% of the lesions, the anterior mediastinum contains 26% and the middle mediastinum II %. The majority of the tumors are benign in character with a ratio of benign to malig nant of about 60 to 40. The relative incidence of malignant mediastinal tumors in children is about 50%. Even though mediastinal tumors are not common, they represent a unique problem with regards to treatment whether by surgery, radiation therapy and/or systemically administered chemotherapy. The volume by WOOD and THOMAS deals with each of these issues in detail and presents a logical and important approach to the management of mediastinal tumors.
By doing so, the text aims to improve the treatment and assessment of patients with mediastinal tumors. This book focuses on daily practice, as pathologists are confronted with this type of pathology regularly.
Author: Neda Kalhor
The mediastinum is a hollow space within the thoracic cavity that may give rise to a wide spectrum of tumoral conditions from the benign to the intermediate to the highly malignant neoplasms. In addition, other inflammatory and infectious conditions may also arise in this space, which renders the practice of mediastinal pathology, almost a general surgical pathology practice. However, there are numerous mediastinal conditions that are important not only for diagnosis but also for treatment and clinical outcome. Due to the unusual location and because of the complexity of the tumors occurring in the mediastinum, there are only a few experts in this particular anatomic area. In fact, there are no more than 3-4 individuals worldwide with enough experience to properly diagnose, classify, and make treatment suggestions when these tumors arise in the mediastinum. More recent developments in tumor diagnosis and classification have created a vacuum in the general pathologist who often is confronted with this pathology and becomes uneasy about the specifics. For instance, recent developments in tumor pathology have led to the classification and staging of mediastinal tumors in more innovative ways that are in need of proper highlighting. Needless to say, even though there are a few publications on mediastinal pathology, the books are either obsolete or incomplete, in addition of providing superficial knowledge. Unfortunately and with all due respect to the authors of those publications, neither of those books is written by experts in the area. Rather the books were written out of the lack of information in mediastinal pathology. Even the World Health Organization (WHO) publication, which is truly more on lung and pleural neoplasms, has inserted in its contents a portion of mediastinal tumors, such portion not only is superficial and incomplete but also at least highly controversial if not flat out incorrect. . This text’s goal is to present comprehensive and up to date information of the diverse pathology that can be encountered in the mediastinal compartment. The book will be divided in 11 different chapters based on the lineage of the diverse tumors that occur in the mediastinum, i.e. epithelial, neuroendocrine, lymphoid, etc (see table of contents). In addition, two separate chapters will be included -one on the radiological aspects and the others on the surgical approach to the different mediastinal tumors., bringing a total of 13 chapters. In the pathology section, the book will include current staging and classification systems of the different tumors. In addition, it will address the most current criteria for diagnosis and the differential diagnosis. Although the emphasis of the book is on diagnostic surgical pathology, every chapter will include the use of immunohistochemical techniques, electron microscopy, and molecular biology when necessary. The book will be extensively illustrated so that the reader will benefit of the different histomorphology of mediastinal tumors. Because of the nature of this specific anatomic area and the need to develop a standard text, Mediastinal Pathology should be of high interest to general surgical pathologists, thoracic pathologists in particular as well as thoracic surgeons, oncologists, and radiologists. Needless to say, this book will be of interest to pathology residents and fellows as well as to those seeking more in depth knowledge of thoracic – mediastinal pathology.
For example, in a report from the Roswell Park Cancer Institute,39 90% of the mediastinal tumors were malignant. ... A more commonly accepted incidence of
malignancy in adults with mediastinal masses ranges from 24% to 47%.9,34,40 ...
Author: Thomas W. Shields
Publisher: Lippincott Williams & Wilkins
Long considered the bible of thoracic surgery, this comprehensive text guides readers through open and endoscopic surgical techniques with expert commentary by the leaders in thoracic surgery. Coverage includes extensive sections on lung cancer and other pulmonary tumors. Includes access to a companion Web site.
In patients with malignant lesions , invasion of mediastinal structures can be
diagnosed and tumor can be localized for radiotherapy . Also , CT can ...
Magnetic resonance , however , has two advantages in the diagnosis of mediastinal mass .
An unusual cause of a superior mediastinal mass is a cervical aortic arch that
was reported by Hellenbrand and associates ( 1978 ) . This can cause superior
mediastinal widening and compression of the trachea , along with absence of the
The mediastinum is the most frequent site of origin of extragonadal germ cell
tumors . Indeed , these neoplasms account for approximately 20 % of all anterior
and superior mediastinal tumors and cysts ( 51,52 ) . All pathologic variants of
Utility of PET in the mediastinum; Diagnostic strategies for mediastinal tumors and masses; Infections of the mediastinum; Genetic markers of mediastinal diseases; Mediastinal tumors and cysts in the pediatric population; Multimodality ...
Author: Federico Venuta
Publisher: W B Saunders Company
Utility of PET in the mediastinum; Diagnostic strategies for mediastinal tumors and masses; Infections of the mediastinum; Genetic markers of mediastinal diseases; Mediastinal tumors and cysts in the pediatric population; Multimodality treatment of germ cell tumors of the mediastinum; Surgical approaches to the thymus in patients with MG; Multimodality treatment of thymoma; Vascular lesions of the mediastinum; Combined cervico - thoracic approaches for complex mediastinal masses; Intraoperative strategy in patients with extended involvement of mediastinal structures; The role of surgical resection for locally recurring mediastinal tumors; Modern Radiotherapy for Mediastinal Disease; Surgery of the mediastinum -historical notes.
These merge with the retrocrural lymph - node chain , and the para - aortic nodes
on the abdomen . Evaluation of mediastinal masses Most patients who have a mediastinal mass present with symptoms from the local compressive or invasive
Author: Richard K. Albert
Category: Respiratory infections
COMPREHENSIVE RESPIRATORY MEDICINE is a revolutionary new reference designed to help the physician provide the highest standard of care for patients with respiratory disease. This comprehensive, clinically focused reference is the only text available that provides complete coverage of respiratory medicine in one, full-color volume. The first section covers examination of the patient, signs and symptoms, modern assessment techniques, and an outstanding highly illustrated imaging chapter. The second disease based section covers the wide spectrum of cases seen in clinical practice. * Integrates basic science with a clinical focus, reflecting the way physicians practice. * Brings to life the science of respiratory medicine by explaining real-life, clinical situations. * Comprehensively covers all areas necessary when diagnosing, treating and managing a patient. * Written by experts in the field who present an international perspective of the subject. * Combines all information in a single volume, which is easy to carry and reference quickly. * Features fantastic full color artwork program to help explain difficult concepts in diagnosis and to promote understanding of the principles behind the disease. * Includes critical referencing system. Spanish version also available, ISBN: 84-8174-527-8
vergence sign , iceberg sign , silhouette sign , and cervicothoracic sign aid in the
localization of mediastinal masses on the PA radiograph . However , the lateral
view is critical for localization of the mass into one of the three previously ...
Author: Derek C. Harwood-Nash
Publisher: Merit Pub International
Category: Children - Radiology
Bogen koncentrer sig om neuroradiologi og pædiatriske røntgenundersøgelser.
Radiologically , mediastinal meningoceles usually right sided in position , and
usually simulate the much more frequently occur - large in size . The mass is
connected to the ring solid neurogenic tumors . They should duodenum or
Mediastinal Mass Thomas G. Tape , MD Key Points Pretest Probabilities • The
differential diagnosis of a mediastinal ... Less than 50 % of primary mediastinal tumors are malignant , but the presence of symptoms at diagnosis considerably ...
Author: Robert J. Panzer
Publisher: Amer College of Physicians
This book details the logical evaluative steps for interpreting diagnostic information about various common diseases and conditions. In the opening chapters the principles and applications of quantitative decision making are outlined. Subsequent chapters discuss these diagnostic techniques in relation to 49 specific medical problems, including acute pancreatitis, coronary artery disease, hyperthyroidism, and erythrocytosis, among others.
In one series of revealed a calcified mass arising from the posteri mediastinal masses presenting in 62 children , or mediastinum with no evidence of
abdominal 52 % were posterior and 38 % were anterior.5 involvement . Results
of a bone ...
Stephen C. Yang, Duke E. Cameron. MIDDLE MEDIASTINAL MASSES George L
. Zorn III . ... Rarely , angiography is required to define the vascular anatomy in
relation to a middle mediastinal mass . Magnetic resonance imaging is useful for
Author: Stephen C. Yang
Publisher: Mosby Incorporated
More than 200 noted authorities discuss their views on diagnosis, treatment, and procedures, with advice on everything from assessment and imaging through incisions, anesthesia, and perioperative care issues--including cardiac pacing in adults and children, and the cardiac surgery "fast track." It is packed with "high-yield" information that helps the user to access needed knowledge in the least amount of time.
Table • 231-1 Differential Diagnoses for Lesions Associated with Focal
Mediastinal Enlargement 47 tumors that can ... tumors often invade and surround
roots of the great vessels at the heart base , they result in a mediastinal mass
Author: Stephen J. Ettinger
"Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource for veterinary internal medical problems. The internationally acclaimed "gold standard" offers unparalleled coverage of pathophysiology, diagnosis, and treatment of diseases affecting dogs and cats, as well as the latest information on the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, cancer vaccines, and more. The 7th edition combines the convenience of a two-volume printed textbook with the enhanced functionality of a regularly updated Expert Consult website that enables you to electronically search your entire book and study more efficiently. With instant access to the most reliable, up-to-date information available, you'll always be at the forefront of veterinary care!" --Book Jacket.
CT OF THE MEDIASTINUM - Fig . 8. Extent and contour of tumor arising in. Vol .
128 Tomography 81 TABLE I : PRIMARY LUNG CARCINOMAS : HISTOLOGIC
DISTRIBUTION 44 All cases Squamous cell Adenocarcinoma Undifferentiated ...
This sign is referred to as the “ silhouette sign , " although there is actually de -
silhouetting of the normal structure by the mass . This apparent loss of the margin
of the normal structure can be А M P used to localize a mediastinal mass to the ...
Category: Diagnostic ultrasonic imaging
Each issue includes separate but continuously paged sections called: Nuclear medicine, and: Ultrasound