The Evolution of the Genome

The Evolution of the Genome

The Evolution of the Genome provides a much needed overview of genomic study through clear, detailed, expert-authored discussions of the key areas in genome biology.

Author: T. Ryan Gregory

Publisher: Elsevier

ISBN: 0080470521

Category: Science

Page: 768

View: 723

The Evolution of the Genome provides a much needed overview of genomic study through clear, detailed, expert-authored discussions of the key areas in genome biology. This includes the evolution of genome size, genomic parasites, gene and ancient genome duplications, polypoidy, comparative genomics, and the implications of these genome-level phenomena for evolutionary theory. In addition to reviewing the current state of knowledge of these fields in an accessible way, the various chapters also provide historical and conceptual background information, highlight the ways in which the critical questions are actually being studied, indicate some important areas for future research, and build bridges across traditional professional and taxonomic boundaries. The Evolution of the Genome will serve as a critical resource for graduate students, postdoctoral fellows, and established scientists alike who are interested in the issue of genome evolution in the broadest sense. Provides detailed, clearly written chapters authored by leading researchers in their respective fields Presents a much-needed overview of the historical and theoretical context of the various areas of genomic study Creates important links between topics in order to promote integration across subdisciplines, including descriptions of how each subject is actually studied Provides information specifically designed to be accessible to established researchers, postdoctoral fellows, and graduate students alike
Categories: Science

Ecological Genomics

Ecological Genomics

We provide an advanced-level book that covers this recent research and proposes future development for this field. A synthesis of the field of ecological genomics emerges from this volume.

Author: Christian R. Landry

Publisher: Springer Science & Business Media

ISBN: 9789400773479

Category: Science

Page: 359

View: 542

Researchers in the field of ecological genomics aim to determine how a genome or a population of genomes interacts with its environment across ecological and evolutionary timescales. Ecological genomics is trans-disciplinary by nature. Ecologists have turned to genomics to be able to elucidate the mechanistic bases of the biodiversity their research tries to understand. Genomicists have turned to ecology in order to better explain the functional cellular and molecular variation they observed in their model organisms. We provide an advanced-level book that covers this recent research and proposes future development for this field. A synthesis of the field of ecological genomics emerges from this volume. Ecological Genomics covers a wide array of organisms (microbes, plants and animals) in order to be able to identify central concepts that motivate and derive from recent investigations in different branches of the tree of life. Ecological Genomics covers 3 fields of research that have most benefited from the recent technological and conceptual developments in the field of ecological genomics: the study of life-history evolution and its impact of genome architectures; the study of the genomic bases of phenotypic plasticity and the study of the genomic bases of adaptation and speciation.
Categories: Science

Genome Evolution

Genome Evolution

This collection of papers will be of interest to all academic and industry researchers working in the fields of molecular biology, biotechnology, genomics and genome centers.

Author: Axel Meyer

Publisher: Springer Science & Business Media

ISBN: 9789401002639

Category: Science

Page: 237

View: 789

In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until recent methodological advances. This book evaluates newly generated empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context, provide evidence regarding the relative importance of gene duplication. The alternative explanation is that the evolution of regulatory elements that control the expression of and interactions among genes has been a more important force in shaping evolutionary innovation. This collection of papers will be of interest to all academic and industry researchers working in the fields of molecular biology, biotechnology, genomics and genome centers.
Categories: Science

The Evolution of Genome Size

The Evolution of Genome Size

This book discusses both the evolutionary causes and the molecular mechanisms of changes in genome size.

Author: Wily

Publisher: John Wiley & Sons

ISBN: UCSD:31822002224467

Category: Chromosomes

Page: 523

View: 641

This book discusses both the evolutionary causes and the molecular mechanisms of changes in genome size. It emphasises the universal posistive correlation between genome size and cell volume, and discusses both natural and experimentally induced changes.
Categories: Chromosomes

Evolution of the Human Genome II Human Evolution Viewed from Genomes

Evolution of the Human Genome II  Human Evolution Viewed from Genomes

This book stands out as the most comprehensive book on the modern human evolution, focusing on genomic points of view with a broad scope. Primary target audiences are researchers and graduate students in evolutionary biology.

Author: Naruya Saitou

Publisher: Evolutionary Studies

ISBN: 4431569057

Category: Medical

Page:

View: 441

Categories: Medical

The Origins of Genome Architecture

The Origins of Genome Architecture

This text explains why the details matter and presents a framework for how the architectural diversity of eukaryotic genomes and genes came to arise.

Author: Michael Lynch

Publisher: Sinauer

ISBN: UOM:49015003406510

Category: Medical

Page: 494

View: 561

The availability of genomic blueprints for hundreds of species has led to a transformation in biology, encouraging the proliferation of adaptive arguments for the evolution of genomic features. This text explains why the details matter and presents a framework for how the architectural diversity of eukaryotic genomes and genes came to arise.
Categories: Medical

Evolution Development and the Predictable Genome

Evolution  Development  and the Predictable Genome

This book provides a clear and wide-ranging introduction to evolution and development for the basic reader; graduate students will be introduced to the cutting-edge of research in evolutionary developmental biology; and experts in evolution ...

Author: David L. Stern

Publisher: Roberts & Company

ISBN: STANFORD:36105215333076

Category: Science

Page: 264

View: 199

For too long, efforts to synthesize evolution and development have failed to build a united view of the origins and evolution of biological diversity. In this groundbreaking book, David Stern sets out to draw evolutionary biology and developmental biology together by cutting through the differences that divide the disciplines and by revealing their deeper similarities. He draws upon the insights of generations of evolutionary biologists and scores of developmental biologists to build a solid foundation for future investigation of the genetic and developmental causes of diversity. Along the way, and in plain English, he explicates many of the guiding principles of evolution, population genetics, and developmental biology. Each chapter offers a clear review of fundamental principles, together with thoughtprovoking ideas that will be tested only with data emerging from current and future studies. With the basic principles established, he then offers a new way of thinking about development—backwards—to clarify precisely how the mechanisms of development influence evolution. In the same spirit, he takes a fresh look at evolution in populations, arguing that population history influences precisely how developmental mechanisms evolve. Both Stern's new perspective on development and his reassessment of the role of populations leads to the surprising conclusion that the evolution of genomes appears to be predictable. Stern argues that developmental biology and evolutionary biology are intertwined: it is impossible to understand one of them fully without understanding the other. This book provides a clear and wide-ranging introduction to evolution and development for the basic reader; graduate students will be introduced to the cutting-edge of research in evolutionary developmental biology; and experts in evolution or development will receive both an uncomplicated introduction to the other discipline and an abundance of new, provocative ideas.
Categories: Science

Darwin in the Genome

Darwin in the Genome

The enthralling story of strategic genomes and the revolutionary discoveries at the cutting edge of bio-research.

Author: Lynn Helena Caporale

Publisher: Darwin in the Genome

ISBN: 9780071378222

Category: Science

Page: 245

View: 322

Smart genomes--an enthralling account of revolutionary discoveries at the cutting edge of genomics research Written by a molecular biologist at the forefront of genomics research, Darwin in the Genome is an exciting account of one of the hottest new theories in biology today: evolution by natural selection inevitably leads to strategic mutations. In the struggle for survival, from pathogens to flowers, birds to orangutans, baker's yeast to people, the fittest genomes are those that evolve effective molecular strategies that respond to, and in fact anticipate, challenges and opportunities in their environments. Writing in a clear, accessible style, Lynn Caporale describes the emergence of genomic mutation strategies, which researchers are just beginning to uncover. She also spells out some of the more profound implications of these findings, including the importance of biodiversity, indeed human diversity, for survival, the possibility of bold new directions for medical research, and the inherent dangers of attempting to fix perceived "errors" in a human genome.
Categories: Science

Structural and Evolutionary Genomics

Structural and Evolutionary Genomics

These subjects are closely interlinked. They are approached in this book using as a guideline the investigations carried out in the author's laboratory, relevant literature is critically reviewed and some general conclusions are presented.

Author: Giorgio Bernardi

Publisher: Gulf Professional Publishing

ISBN: 0444512551

Category: Evolutionary genetics

Page:

View: 933

Structural genomics is the study of the DNA of living organisms. Evolutionary genomics is the study of the history of the genome. These subjects are closely interlinked. They are approached in this book using as a guideline the investigations carried out in the author's laboratory, relevant literature is critically reviewed and some general conclusions are presented. The author and his collaborators have studied a vast number of genomes, ranging from prokaryotes to human, using different approaches, including physical chemistry of DNA, viral integration and molecular cytogenetics.
Categories: Evolutionary genetics

Evolution of the Human Genome I

Evolution of the Human Genome I

This book furnishes readers with a good summary of current research in the field. This book reviews the human genome from an evolutionary perspective.

Author: Naruya Saitou

Publisher: Springer

ISBN: 9784431566038

Category: Science

Page: 305

View: 254

This book reviews the human genome from an evolutionary perspective. No such book has ever been published before, although there are many books on human genomes. There are two parts in this book: Overview of the Human Genome (Part I) and The Human Genome Viewed through Genes (Part II). In Part I, after a brief review of human evolution and the human genome (by Naruya Saitou), chapters on rubbish or junk DNA (by Dan Graur), GC content heterogeneity (by Satoshi Oota), protein coding and RNA coding genes (by Tadashi Imanishi), duplicated genes (by Takashi Kitano), recombinations (by Montanucci and Bertranpetit), and copy number variations including microsatellites (by Naoko Takezaki) are discussed. Readers can obtain various new insights on the human genome from this part. In Part II, genes in X and Y chromosomes (by Yoko Satta and others), HLA genes (by Timothy A. Jinam), opsin genes (by Shoji Kawamura and Amanda D. Melin), genes related to phenotypic variations (by Ryosuke Kimura), transcription factors (by Mahoko Takahashi and So Nakagawa), diabetes-related genes (by Ituro Inoue), disease genes in general (by Ituro Inoue and Hirofumi Nakaoka), and microbial genomes (by Chaochun Wei) are discussed. The human genome sequences were determined in 2004, and after more than 10 years we are now beginning to understand the human genome from an evolutionary point of view. This book furnishes readers with a good summary of current research in the field.
Categories: Science

Genetics

Genetics

Genetics: Genes, Genomes, and Evolution unites evolution, genomics, and genetics in a single narrative approach. It is an approach that provides students with a uniquely flexible and contemporary view of genetics, genomics, and evolution.

Author: Philip Meneely

Publisher: Oxford University Press

ISBN: 9780198795360

Category: Science

Page: 740

View: 843

Recent advances that allow scientists to quickly and accurately sequence a genome have revolutionized our view of the structure and function of genes as well as our understanding of evolution. A new era of genetics is underway, one that allows us to fully embrace Dobzhansky's famous statement that "Nothing in biology makes sense except in the light of evolution". Genetics: Genes, Genomes, and Evolution presents the fundamental principles of genetics and molecular biology from an evolutionary perspective as informed by genome analysis. By using what has been learned from the analyses of bacterial and eukaryotic genomes as its basis, the book unites evolution, genomics, and genetics in one narrative approach. Genomic analysis is inherently both molecular and evolutionary, and every chapter is approached from this unified perspective. Similarly, genomic studies have provided a deeper appreciation of the profound relationships between all organisms - something reflected in the book's integrated discussion of bacterial and eukaryotic evolution, genetics and genomics. It is an approach that provides students with a uniquely flexible and contemporary view of genetics, genomics, and evolution. Online Resource Centre: - Video tutorials: a series of videos that provide deeper, step-by-step explanations of a range of topics featured in the text. - Flashcards: electronic flashcards covering the key terms from the text. For registered adopters of the text: - Digital image library: Includes electronic files in PowerPoint format of every illustration, photo, graph and table from the text - Lecture notes: Editable lecture notes in PowerPoint format for each chapter help make preparing lectures faster and easier than ever. Each chapter's presentation includes a succinct outline of key concepts, and incorporates the graphics from the chapter - Library of exam-style questions: a suite of questions from which you can pick potential assignments and exams. - Test bank of multiple-choice questions: a ready-made electronic testing resource that can be customized by lecturers and delivered via their institution's virtual learning environment. - Solutions to all questions featured in the book: solutions written by the authors help make the grading of homework assignments easier. - Journal Clubs: a series of questions that guide your students through the reading and interpretation of a research paper that relates to the subject matter of a given chapter. Each Journal club includes model answers for lecturers. - Instructor's guide: The instructor's guide discusses the educational approach taken by Genetics: Genes, Genomes, and Evolution in more detail, why this approach has been taken, what benefits it offers, and how it can be adopted in your class.
Categories: Science

Ancestors in Our Genome

Ancestors in Our Genome

Geneticist Eugene Harris presents us with the complete and up-to-date account of the evolution of the human genome.

Author: Eugene E. Harris (Professor)

Publisher: Oxford University Press, USA

ISBN: 9780199978038

Category: Science

Page: 226

View: 683

Geneticist Eugene Harris presents us with the complete and up-to-date account of the evolution of the human genome.
Categories: Science

Plant Genome Diversity Volume 2

Plant Genome Diversity Volume 2

Together with Volume I, this comprehensive book on the plant genome is intended for students and professionals in all fields of plant science, offering as it does a convenient entry into a burgeoning literature in a fast-moving field.

Author: Johann Greilhuber

Publisher: Springer Science & Business Media

ISBN: 9783709111604

Category: Science

Page: 356

View: 610

This second of two volumes on Plant Genome Diversity provides, in 20 chapters, insights into the structural evolution of plant genomes with all its variations. Starting with an outline of plant phylogeny and its reconstruction, the second part of the volume describes the architecture and dynamics of the plant cell nucleus, the third examines the evolution and diversity of the karyotype in various lineages, including angiosperms, gymnosperms and monilophytes. The fourth part presents the mechanisms of polyploidization and its biological consequences and significance for land plant evolution. The fifth part deals with genome size evolution and its biological significance. Together with Volume I, this comprehensive book on the plant genome is intended for students and professionals in all fields of plant science, offering as it does a convenient entry into a burgeoning literature in a fast-moving field.
Categories: Science

Genomics of Chloroplasts and Mitochondria

Genomics of Chloroplasts and Mitochondria

This book, written by leading experts, summarizes our current knowledge about plastid and mitochondrial genomes in all major groups of algae and land plants.

Author: Ralph Bock

Publisher: Springer Science & Business Media

ISBN: 9789400729209

Category: Science

Page: 475

View: 757

The past decade has witnessed an explosion of our knowledge on the structure, coding capacity and evolution of the genomes of the two DNA-containing cell organelles in plants: chloroplasts (plastids) and mitochondria. Comparative genomics analyses have provided new insights into the origin of organelles by endosymbioses and uncovered an enormous evolutionary dynamics of organellar genomes. In addition, they have greatly helped to clarify phylogenetic relationships, especially in algae and early land plants with limited morphological and anatomical diversity. This book, written by leading experts, summarizes our current knowledge about plastid and mitochondrial genomes in all major groups of algae and land plants. It also includes chapters on endosymbioses, plastid and mitochondrial mutants, gene expression profiling and methods for organelle transformation. The book is designed for students and researchers in plant molecular biology, taxonomy, biotechnology and evolutionary biology.
Categories: Science

Human Genome Evolution

Human Genome Evolution

The reviews in this volume in the Human Molecular Genetics series have been written by active researchers in key areas of human genome evolution.

Author: Michael S. Jackson

Publisher:

ISBN: 0122204476

Category: Science

Page: 320

View: 449

Our understanding of human genome evolution has improved dramatically over the last decade, influenced both by technological advances and directed genome mapping programmes. This volume brings together, for the first time, data concerning the evolution of genes, multigene families and nongenic sequences in the human genome and provides a comprehensive review of this rapidly changing filed. Human Genome Evolution also considers specific areas of the genome, such as the sex chromosomes, which have been subject to unusual evolutionary forces as well as covering more general topics, including the evolution of human proteins by exon shuffling and the use of genetic polymorphisms to study human evolution. The reviews in this volume in the Human Molecular Genetics series have been written by active researchers in key areas of human genome evolution. The book is therefore an authoritative reference source for postgraduates and researchers in human molecular genetics and evolution, and provides a valuable overview of the subject to final year undergraduates with an interest in evolution.
Categories: Science

Nature Encyclopedia of the Human Genome Genome databases Mitochondrial genome Evolution

Nature Encyclopedia of the Human Genome  Genome databases   Mitochondrial genome  Evolution

References Haig D and Graham C ( 1991 ) Genomic imprinting and the strange
case of insulin - like growth factor II receptor . Cell 64 ... Spencer HG ( 2000 )
Population genetics and evolution of genomic imprinting . Annual Review of
Genetics ...

Author: David Neil Cooper

Publisher:

ISBN: UOM:39015056925871

Category: Human genetics

Page: 1023

View: 586

The recent completion of important phases of the Human Genome Project heralds a new era in biomedical research, ensuring that human genetics will remain at the forefront of the public, scientific and educational consciousness. 'The Nature Encyclopedia of the Human Genome' (Nature EHG) will be the first major reference resource devoted entirely to the scientific basis and ethical, philosophical and commercial ramifications of genome research. Nature EHG will contain 1,000 articles, specially written by the world's leading experts and structured in such a way that different subsets will be useful to students, teachers, academics, researchers, and other professionals. The articles will be extensively cross-referenced and indexed and will contain many tables and illustrations. Areas to be covered include structural genomics, functional genomics, evolution and comparative genomics, genome mapping and sequencing, chromosome structure and function, population and mathematical genetics, bioinformatics, proteomics, genes and disease, behavioural and psychiatric genetics and ethical, legal and social issues.
Categories: Human genetics

Genomics

Genomics

People sometimes suggest that human evolution has slowed down or come to an
end, but evolution continues because new pathogens ... The evolution of the
human brain: https://www.yourgenome.org/ stories/evolution-of-the-human-brain.
3.

Author: Julian Parkhill

Publisher: Oxford University Press, USA

ISBN: 9780198848387

Category:

Page: 200

View: 541

This Oxford Biology Primer will introduce students to the field of genomics and its applications. From the early days of the Human Genome Project, sequencing technology has rapidly developed and is now cheaper and more accessible than ever before. The resulting pervasive nature of these technologies make them more likely to be experienced by people as patients, consumers and citizens. The primer introduces the basic principles of genomics and then uses these to consider human genetics, through examples of some of the rare diseases linked to single genes. The impact of these rare diseases is far-reaching and the knowledge gained through genome sequencing is proving invaluable in their diagnosis. Genome sequencing is revolutionising the diagnosis and treatment of cancer, and the primer introduces students to some of the key breakthroughs which have taken place in recent years. These include the identification of specific genes indicating cancer risk, and the sequencing of tumours throughout treatment to identify further mutations and modify treatment accordingly. The primer aims to address a number of the ethical issues which are raised by this rapidly-growing area of biology. Students are challenged to consider some of the decisions they may need to make relating to these technologies in their own lives, and are given opportunities to explore different aspects of these issues in a way which allows discussion to be both informed and meaningful. The study of infectious disease is also feeling the impact of genomics: the primer discusses the concept of pathogen genome sequencing, and illustrates the various ways in which this can be used - for example, enabling us to find different solutions to infections, to track outbreaks of disease to their source, and to identify and possibly ultimately combat antibiotic resistance. Many of the major diseases which impact the global population are caused by parasites, which come in a wide variety of shapes and sizes. The primer introduces students to the importance of understanding parasite genomes. Parasite genome sequencing makes it possible to develop both new medicines, and new treatments such as gene drive systems to wipe out disease-causing mosquito populations. For many years, our views of classification and evolution have been based on observational techniques going back to Darwin and Linnaeus. Focusing on human evolution, the primer will open students' eyes to the ways in which genome sequencing is being used to reveal evolutionary links that have never before been recognised, and to elucidate the way humans spread out of Africa across the world. Students are not always aware of the role technological developments play in enabling the progress of science. The final chapter delves into how genome sequencing technologies have developed, considering both the speed of change in the technology, its implications for usefulness, availability and cost, and the growing issue of big data and how it can be manipulated. The different technologies described in this chapter are referenced throughout the book.
Categories:

Mutation Selection the Evolution of Microsatellite Loci in Microbial Genomes

Mutation  Selection   the Evolution of Microsatellite Loci in Microbial Genomes

These repeats contribute differently to the global features of these genomes , and
we explore the evolutionary ... These results have important potential implications
for understanding genome stability and evolution in these microbial species .

Author: Dawn Field

Publisher:

ISBN: UCSD:31822020737375

Category:

Page: 180

View: 742

Categories:

Bones Brains and DNA

Bones  Brains and DNA

Explores the tools and methods used to study human origins and discusses milestones in human evolution, human movement across the planet, and the beginnings of being human through language, music, art, and technology.

Author: Ian Tattersall

Publisher: Bunker Hill Publishing, Inc.

ISBN: 159373056X

Category: Juvenile Nonfiction

Page: 47

View: 526

Explores the tools and methods used to study human origins and discusses milestones in human evolution, human movement across the planet, and the beginnings of being human through language, music, art, and technology.
Categories: Juvenile Nonfiction

Gene and Protein Evolution

Gene and Protein Evolution

Providing an excellent update on gene and protein evolution, this book will be appreciated by researchers in biology and medicine, biology teachers and anyone interested in evolution and genomics."--Publisher's description.

Author: Jean-Nicolas Volff

Publisher: Karger Medical and Scientific Publishers

ISBN: 9783805583404

Category: Medical

Page: 194

View: 639

"Our way of understanding evolution has changed completely with the era of genomics, particularly since the emergence of comparative genomics, a discipline allowing the analysis of complete genomes and biological processes over vast periods of time. In this volume, internationally recognized experts present and discuss an update of the evolutionary processes at the onset of organismal diversification and complexity, and review the mechanisms leading to the acquisition of new traits and functions. Different levels of evolution are considered, from internal modules in genes and proteins to interactomes and biological networks, with integration of the influence of both the genomic environment and the ecological context. Particular emphasis will be given to the origin of novel genes and gene functions as well as to the evolutionary impact of the duplication of genetic information, with several chapters devoted to transposable elements. Providing an excellent update on gene and protein evolution, this book will be appreciated by researchers in biology and medicine, biology teachers and anyone interested in evolution and genomics."--Publisher's description.
Categories: Medical