4 (2007): 34851 ——, Thomas J. Moore, Alan Scoboria and Sarah S. Nicholls, ' The Emperor's New Drugs: An Analysis of Antidepressant Medication Data
Submitted to the U.S. Food and Drug Administration', Prevention & Treatment, no.
Author: Irving Kirsch
Publisher: Hachette UK
Do antidepressants work? Of course—everyone knows it. Like his colleagues, Irving Kirsch, a researcher and clinical psychologist, for years referred patients to psychiatrists to have their depression treated with drugs before deciding to investigate for himself just how effective the drugs actually were. Over the course of the past fifteen years, however, Kirsch's research—a thorough analysis of decades of Food and Drug Administration data—has demonstrated that what everyone knew about antidepressants was wrong. Instead of treating depression with drugs, we've been treating it with suggestion. The Emperor's New Drugs makes an overwhelming case that what had seemed a cornerstone of psychiatric treatment is little more than a faulty consensus. But Kirsch does more than just criticize: he offers a path society can follow so that we stop popping pills and start proper treatment for depression.
As a clinical psychologist, I referred depressed psychotherapy clients to
psychiatric colleagues for the prescription of medication, believing that it might
help. Sometimes the antidepressant seemed to work; sometimes it did not. When
it did work ...
Author: Irving Kirsch
Publisher: Random House
Category: Business & Economics
Everyone knows that antidepressant drugs are miracles of modern medicine. Professor Irving Kirsch knew this as well as anyone. But, as he discovered during his research, there is a problem with what everyone knows about antidepressant drugs. It isn't true. This is not a book about alternative medicine and its outlandish claims. This is a book about fantasy and wishful thinking in the heart of clinical medicine, about the seductions of myth, and the final stubbornness of facts. BRAIN SHOTS: The Byte-sized exposé of the pharmaceutical industry
St John's wort, conventional medication, and placebo: an egregious double
standard. Complementary Therapies in Medicine, 11(3), 193–195. DOI: 10.1016/
S0965-2299(03)00109–2 Kirsch, I. (2009). The emperor's new drugs: exploding
Author: Amir Raz
Publisher: Oxford University Press
Why do red placebos stimulate whereas blue placebos calm? Why do more placebos work better than few? And why do more expensive placebos work better than cheaper ones? These are some of the key questions that often come to mind when we consider the slippery and counterintuitive field of placebo science. Rather than consider placebos through the narrow narrative of "sugar pills" in clinical trials, this book provides various perspectives on how psychosocial parameters - such as interpersonal rapport, historical and contemporary context, corporate memory, expectation, empathy, hope, conditioning, symbolic thinking, and suggestion - play a role in forming placebo responses and placebo effects. The book provides modern perspectives on placebos in society, including in education, government, industry, media, and modern culture. The editors use three different lenses to elucidate modern conceptualizations of placebos and their accouterments: the Practitioner lens, the Cultural lens, and the popular lens of food and dietary products. These accounts, by some of the best scholars in the field, make for a cogent triangulation of the qualities and virtues of placebos across a wide range of disciplines relevant to human behavior. Placebo Talks invites readers to discover how placebos may speak to their own experiences across health, society, sustenance, and related aspects of contemporary life.
Many of you will be familiar with the story of the Emperor's New Clothes, a lovely
little tale of deception in which a whole country, starting with its Emperor and all
his most trusted advisors and then everybody else in the land were hoodwinked ...
Author: Christopher Holmes
In the long-running debate about whether tobacco-smoking is a habit or an addiction, this book is surely the last word. Here, the notion that it's a drug addiction is systematically torn apart, and smoking is emphatically re-defined as a Compulsive Habit, which hypnotherapy can shut down. Cravings are proven to be unrelated to nicotine, and Nicotine Replacement is denounced as a bogus therapy. This lively and irreverent book will be a delight to readers who have issues with the pharmaceutical industry and the medical establishment. This therapist has attitude!
The makers, Wyeth, are now moving their marketing muscle behind a new, but
similar kind of, drug called Pristiq. Together, antidepressant and anti-psychotic drugs are bringing in over $30 billion a year for the pharmaceutical industry. But
Author: Patrick Holford
Publisher: Hachette UK
Category: Health & Fitness
Low mood, motivation and depression are endemic, and on the increase. About 40% of all GP visits are for people feeling depressed. In America recent figures show that one in ten have been prescribed anti-depressants. The recession has fuelled the need for the feel good factor. This book, written by leading nutrition expert and psychologist delivers highly effective ways - nutritional and psychological, with practical lifestyle and life management techniques - that really make a difference to how you feel. If you eat the right foods, avoid the wrong ones, your mood will improve dramaticaly - and quickly. Patrick Holford's approach is supported by substantial research, and backed up by poignant and motivating case histories. It also includes case histories of those at the suicidal end of depression who failed to get better with conventional approaches, and recovered completely on Holford's regime. The book would be supported by further in-depth analysis relating to mood and diet taken from Holford's 100% Health survey which was completed by over 55,000 people..
It is by interfering with this process of communication among neurons that
psychiatric drugs affect feelings, thoughts, and ... Kirsch, The Emperor's New Drugs, 82; Patterson, The Therapist's Guide to Psychopharmacology, 15–16; and
Author: Elahe Hessamfar
Publisher: Wipf and Stock Publishers
"Schizophrenia" is by many accounts the most devastating illness of our time. In this book, Elahe Hessamfar uses her personal encounter with her daughter's illness to bring the reader to experience the pain and anguish of those who suffer so intensely. She candidly discusses the gripping and dark realities her family has faced in the midst of this journey and exposes that the ride isn't easy, but it can be fruitful and purposeful, and it can be a journey of joy and peace if understood from the intended perspective. This is a fascinating and deeply theological portrayal of madness under the mighty hand of God. It challenges and awakens the reader to a heightened awareness about self, community, pain, brokenness, sin, grace, and redemption. This is the first truly biblically based, theological interpretation of madness in conversation with psychiatry and social sciences. Hessamfar passionately discusses the shortcomings of our current medical model of mental illness and directs the reader's attention to the mistreatment of those the medical community labels with "schizophrenia." She argues that not only is "schizophrenia" not pathological but it touches on the most fundamental fragilities of the human soul, and hence, it is a critical pastoral issue. Hessamfar offers tangible, inspiring, and life-changing solutions for those dealing with this most elusive and mysterious phenomenon--solutions that would bring hope and healing to the hopeless people chained in the abyss of madness.
Books and articles cited in this passage: Irving Kirsch, The Emperor's New Drugs:
Exploding the Antidepressant Myth (New York: Basic Books, 2011), http://books.
google .com/books?id=wk-OxcTKyi4C; Robert Whitaker, Anatomy of an ...
Author: Andrew Solomon
Publisher: Simon and Schuster
With uncommon humanity, candor, wit, and erudition, award-winning author Andrew Solomon takes the reader on a journey of incomparable range and resonance into the most pervasive of family secrets. His contribution to our understanding not only of mental illness but also of the human condition is truly stunning. The Noonday Demon examines depression in personal, cultural, and scientific terms. Drawing on his own struggles with the illness and interviews with fellow sufferers, doctors and scientists, policymakers and politicians, drug designers and philosophers, Solomon reveals the subtle complexities and sheer agony of the disease. He confronts the challenge of defining the illness and describes the vast range of available medications, the efficacy of alternative treatments, and the impact the malady has had on various demographic populations around the world and throughout history. He also explores the thorny patch of moral and ethical questions posed by emerging biological explanations for mental illness. The depth of human experience Solomon chronicles, the range of his intelligence, and his boundless curiosity and compassion will change the reader's view of the world.
Author: Peter R. Breggin, M.D.Publish On: 2009-05-26
Kirsch, I., T. Moore, A. Scoboria, and S. Nicholls, S. “The Emperor's New Drugs:
An Analysis of Antidepressant Medication Data Submitted to the U.S. Food and
Drug Administration.” Prevention & Treatment 5, article 23 (posted July 15, 2002).
Author: Peter R. Breggin, M.D.
Publisher: St. Martin's Press
Category: Health & Fitness
Medications for everything from depression and anxiety to ADHD and insomnia are being prescribed in alarming numbers across the country, but the "cure" is often worse than the original problem. Medication Madness is a fascinating, frightening, and dramatic look at the role that psychiatric medications have played in fifty cases of suicide, murder, and other violent, criminal, and bizarre behaviors. As a psychiatrist who believes in holding people responsible for their conduct, the weight of scientific evidence and years of clinical experience eventually convinced Dr. Breggin that psychiatric drugs frequently cause individuals to lose their judgment and their ability to control their emotions and actions. Medication Madness raises and examines the issues surrounding personal responsibility when behavior seems driven by drug-induced adverse reactions and intoxication. Dr. Breggin personally evaluated the cases in the book in his role as a treating psychiatrist, consultant or medical expert. He interviewed survivors and witnesses, and reviewed extensive medical, occupational, educational and police records. The great majority of individuals lived exemplary lives and committed no criminal or bizarre actions prior to taking the psychiatric medications. Medication Madness reads like a medical thriller, true crime story, and courtroom drama; but it is firmly based in the latest scientific research and dozens of case studies. The lives of the children and adults in these stories, as well as the lives of their families and their victims, were thrown into turmoil and sometimes destroyed by the unanticipated effects of psychiatric drugs. In some cases our entire society was transformed by the tragic outcomes. Many categories of psychiatric drugs can cause potentially horrendous reactions. Prozac, Paxil, Zoloft, Adderall, Ritalin, Concerta, Xanax, lithium, Zyprexa and other psychiatric medications may spellbind patients into believing they are improved when too often they are becoming worse. Psychiatric drugs drive some people into psychosis, mania, depression, suicide, agitation, compulsive violence and loss of self-control without the individuals realizing that their medications have deformed their way of thinking and feeling. This book documents how the FDA, the medical establishment and the pharmaceutical industry have over-sold the value of psychiatric drugs. It serves as a cautionary tale about our reliance on potentially dangerous psychoactive chemicals to relieve our emotional problems and provides a positive approach to taking personal charge of our lives.
“I put a lot of thought into writing it, believe me. It's time somebody spoke up about
what's happening to music. I decided to be the one.” “And you decided it was a
good idea to put your real name on top of an article criticizing drug dealers ...
Author: Alex Langford
Anthony Adams has a dream of becoming a star. Fresh out of college, he moves to Hollywood to pursue that dream. But as a legitimate musician in a world of 70s disco, he finds rough going. The popular sounds of Donna Summer soon morph into the world of Run DMC and MC Hammer, and Anthony makes his way to New York to keep his dream alive. But the violent early days of rap threaten not only his career, but his life as well.
... antidepressant clinical trials: an analysis of the Food and Drug Administration
database. Arch Gen Psychiatry 2000;57:311–7. 5. Kirsch I, Moore TJ, Scoboria A,
et al. The emperor's new drugs: an analysis of antidepressant medication data ...
Author: David Mintz
Publisher: Elsevier Health Sciences
This issue discusses the diagnosis and treatment of major depressive disorder (MDD) and other depressive disorders, with an emphasis on the psychosocial aspects of depression: how it affects societies, how it is affected by culture, and what the true meaning of recovery is for those suffering from MDD. The issue is divided into three section: Etiology, Diagnosis and Treatment. Authors address the evidence where biology and subjectivity meet. They discuss what is adaptive and what is pathologic and discuss population-based solutions that take into account the specificity of the individual. Authors also take into account combination treatments of psychotherapy and pharmacotherapy and weigh the treatment choices against specific patient subtypes.
Author: Martin E.P. SeligmanPublish On: 2009-11-11
This book examines just how good this symptom relief is when different drugs
and psychotherapies are compared for different psychological ... The Emperor's New Drugs: An Analysis of Antidepressant Medication Data Submitted to the U.S.
Author: Martin E.P. Seligman
In the climate of self-improvement that pervades our culture, there is an overwhelming amount of information about treatments for everything from alcohol abuse to sexual dysfunction. Much of this information is exaggerated if not wholly inaccurate. As a result, people who try to change their own troubling conditions often experience the frustration of mixed success, success followed by a relapse, or outright failure. To address this confusion, Martin Seligman has meticulously analyzed the most authoritative scientific research on treatments for alcoholism, anxiety, weight loss, anger, depression, and a range of phobias and obsessions to discover what is the most effective way to address each condition. He frankly reports what does not work, and pinpoints the techniques and therapies that work best for each condition, discussing why they work and how you can use them to make long lasting change. Inside you’ll discover the four natural healing factors for recovering from alcoholism; the vital difference between overeating and being overweight; the four therapies that work for depression, the pros and cons of anger—and much more. Wise, direct, and very useful, What You Can Change and What You Can’t will help anyone who seeks to change.
Fear and Trembling New York: Penguin Books, 1985. Kirk, Stuart A., and Herb
Kutchins. The Selling of "DSM". The Rhetoric of Science in Psychiatry.
Transaction Publishers, 1992. Kirsch, Irving. The Emperors New Drugs:
Exploding the ...
Author: Scott Stossel
A riveting, revelatory, and moving account of the author’s struggles with anxiety, and of the history of efforts by scientists, philosophers, and writers to understand the condition As recently as thirty-five years ago, anxiety did not exist as a diagnostic category. Today, it is the most common form of officially classified mental illness. Scott Stossel gracefully guides us across the terrain of an affliction that is pervasive yet too often misunderstood. Drawing on his own long-standing battle with anxiety, Stossel presents an astonishing history, at once intimate and authoritative, of the efforts to understand the condition from medical, cultural, philosophical, and experiential perspectives. He ranges from the earliest medical reports of Galen and Hippocrates, through later observations by Robert Burton and Søren Kierkegaard, to the investigations by great nineteenth-century scientists, such as Charles Darwin, William James, and Sigmund Freud, as they began to explore its sources and causes, to the latest research by neuroscientists and geneticists. Stossel reports on famous individuals who struggled with anxiety, as well as on the afflicted generations of his own family. His portrait of anxiety reveals not only the emotion’s myriad manifestations and the anguish anxiety produces but also the countless psychotherapies, medications, and other (often outlandish) treatments that have been developed to counteract it. Stossel vividly depicts anxiety’s human toll—its crippling impact, its devastating power to paralyze—while at the same time exploring how those who suffer from it find ways to manage and control it. My Age of Anxiety is learned and empathetic, humorous and inspirational, offering the reader great insight into the biological, cultural, and environmental factors that contribute to the affliction.
Kirsch, Irving. The Emperor's New Drugs: Exploding the Antidepressant Myth.
New York: Basic Books, 2010. Knab, Tim “Lesser Known Mexican
Psychopharmacogens.” Unpublished manuscript, 1978. Harvard University
Author: Isaac Campos
Publisher: Univ of North Carolina Press
Historian Isaac Campos combines wide-ranging archival research with the latest scholarship on the social and cultural dimensions of drug-related behavior in this telling of marijuana's remarkable history in Mexico. Introduced in the sixteenth century by the Spanish, cannabis came to Mexico as an industrial fiber and symbol of European empire. But, Campos demonstrates, as it gradually spread to indigenous pharmacopoeias, then prisons and soldiers' barracks, it took on both a Mexican name--marijuana--and identity as a quintessentially "Mexican" drug. A century ago, Mexicans believed that marijuana could instantly trigger madness and violence in its users, and the drug was outlawed nationwide in 1920. Home Grown thus traces the deep roots of the antidrug ideology and prohibitionist policies that anchor the drug-war violence that engulfs Mexico today. Campos also counters the standard narrative of modern drug wars, which casts global drug prohibition as a sort of informal American cultural colonization. Instead, he argues, Mexican ideas were the foundation for notions of "reefer madness" in the United States. This book is an indispensable guide for anyone who hopes to understand the deep and complex origins of marijuana's controversial place in North American history.
New York: Simon & Shuster. Los Angeles Times. (1 July 2002). Health Section.
Kirsch, I., Moore, T., Scoboria, A., & Nicholls, S. (2002), The emperor's new drugs.
Prevention and Treatment (5), 22–37. Lynch, T. (2001). Beyond Prozac: Healing
Author: Rogers H. Wright
This book takes as its inspiration the assumption that the atmosphere of intellectual openness, scientific inquiry, aspiration towards diversity, and freedom from political pressure that once flourished in the American Psychological Association has been eclipsed by an "ultra-liberal agenda," in which voices of dissent, controversial points of view, and minority groups are intimidated, ridiculed and censored. Chapters written by established and revered practitioners explore these important issues within the contexts of social change, the ways in which mental health services providers view themselves and their products, and various economic factors that have affected healthcare cost structure and delivery. In short, this book is intended to help consumers, practitioners, and policy makers to become better educated about a variety of recent issues and trends that have significantly changed the mental health fields.
Why the Drug Industry May Be Bad for Your Health J. Douglas Bremner. 17.
Shumaker, S.A. ... S.S. The emperor's new drugs: An analysis of antidepressant
medication data submitted to the U.S. Food and Drug Administration. Available at
Author: J. Douglas Bremner
Category: Health & Fitness
A medical expert reveals risks of the most commonly prescribed drugs-and why the drug industry doesn't want consumers to know about them. Recent scandals involving diabetes drugs, Vioxx, and many other medications reveal the serious and undisclosed risks of some of the most commonly used prescription drugs in this country. In Before You Take That Pill, Dr. J. Douglas Bremner, a researcher and clinician at Emory University whose study on Accutane and depression made headlines, offers an inside look at the pharmaceutical industry, as well as a scientifically backed assessment of the risks of more than three hundred prescribed medications, vitamins, and supplements. While many drugs are essential to the health of consumers, as Dr. Bremner explains, for many people, the benefits may not outweigh the potential side effects. This book contains warnings that are not on the drug labels. It also exposes tricks of the trade that demonstrate how the profit-making interests of "big pharma" may not always be in line with the safety of the public - from the corruption that exists in the drug approval process to the tactics drug companies use to encourage doctors to prescribe their products. Most important, Before You Take That Pill empowers readers by giving them sound information on specific medications so they can understand and weigh the potential risk themselves. Backed by the latest studies, as well as insight from a doctor who is in the trenches, this book should be on the shelf of every drug consumer.
Author: Peter R. Breggin, MDPublish On: 2012-07-19
In a commentary, the two lead authors of the CATIE study underscored the
limitations of the drugs: “By revealing the truth about the emperor's new clothes,
CATIE has helped to refocus efforts on the need for truly innovative treatments
Author: Peter R. Breggin, MD
Publisher: Springer Publishing Company
This is the first book to establish guidelines and to assist prescribers and therapists in withdrawing their patients from psychiatric drugs, including those patients with long-term exposure to antipsychotic drugs, benzodiazepines, stimulants, antidepressants, and mood stabilizers. It describes a method developed by the author throughout years of clinical experience, consultations with experienced colleagues, and scientific research. Based on a person-centered collaborative approach, with patients as partners, this method builds on a cooperative and empathic team effort involving prescribers, therapists, patients, and their families or support network. The author, known for such books as Talking Back to Prozac, Toxic Psychiatry, and Medication Madness, is a lifelong reformer and scientist in mental health whose work has brought about significant change in psychiatric practice. This book provides critical information about when to consider psychiatric drug reduction or withdrawal, and how to accomplish it as safely, expeditiously, and comfortably as possible. It offers the theoretical framework underlying this approach along with extensive scientific information, practical advice, and illustrative case studies that will assist practitioners in multiple ways, including in how to: Recognize common and sometimes overlooked adverse drug effects that may require withdrawal Treat emergencies during drug therapy and during withdrawal Determine the first drugs to withdraw during multi-drug therapy Distinguish between withdrawal reactions, newly occurring emotional problems, and recurrence of premedication issues Estimate the length of withdrawal
This has been done not by science, but by the marketing branches of drug
companies.1 When neurologists who study the brain are asked about the
evidence for the serotonin ... The Emperor's New Drugs: Exploding the
Author: Dr. James Alexander
Publisher: Balboa Press
Category: Health & Fitness
Chronic pain has been correctly described as the invisible crisis at the heart of contemporary life. Despite stunning advances in other areas of medical science, no similar breakthrough in the treatment of chronic pain has resulted from an exclusive focus on the body. Dr James Alexander’s young life was redefined by a tragic car accident in his late teens, and the chronic physical and emotional trauma inspired him to become a psychologist. Now pain-free, Dr Alexander has dedicated the last three decades of his life to helping others overcome similar challenges, specializing in the treatment of chronic pain and psychological trauma. His success is proof that recovery from chronic pain is possible, and this guide offers a valuable resource for working toward that goal. The recovery from chronic pain requires that we revisit and challenge the outdated attitudes and practices that have been used with little result. With the proliferation of medical and psychological research, for the first time we are at a point in history where these notions of pain recovery can be validated by research-based evidence. For too long, Dr Alexander feels, we have been looking in all the wrong places. Specifically, the problem lies at the core of our culture, which still treats the physical and nonphysical aspects of the human as separate experiences. This innovative program involves a journey of self-discovery, a new way to approach medical and psychological care of chronic pain, and advice on the most effective types of help to pursue.
The Emperor's New Drugs: Exploding the Antidepressant Myth. New York: Basic
Books, 2010. ... “Initial Severity and Antidepressant Benefits: A Metaanalysis of
Data Submitted to the Food and Drug Administration.” PLoS Med 5, no. 2 (2008):
Author: SuEllen Hamkins
Publisher: Oxford University Press
Narrative psychiatry empowers patients to shape their lives through story. Rather than focusing only on finding the source of the problem, in this collaborative clinical approach psychiatrists also help patients diagnose and develop their sources of strength. By encouraging the patient to explore their personal narrative through questioning and story-telling, the clinician helps the patient participate in and discover the ways in which they construct meaning, how they view themselves, what their values are, and who it is exactly that they want to be. These revelations in turn inform clinical decision-making about what it is that ails them, how they'd like to treat it, and what recovery might look like. The Art of Narrative Psychiatry is the first comprehensive description of narrative psychiatry in action. Engaging and accessible, it demonstrates how to help patients cultivate their personal sources of strength and meaning as resources for recovery. Illustrated with vivid case reports and in-depth accounts of therapeutic conversations, the book offers psychiatrists and psychotherapists detailed guidance in the theory and practice of this collaborative approach. Drawing inspiration from narrative therapy, post-modern philosophy, humanistic medicine, and social justice movements - and replete with ways to more fully manifest the intentions of the mental health recovery model - this engaging new book shows how to draw on the standard psychiatric toolbox while also maintaining focus on the patient's vision of the world and illuminating their skills and strengths. Written by a pioneer in the field, The Art of Narrative Psychiatry describes a breadth of nuanced, powerful narrative practices, including externalizing problems, listening for what is absent but implicit, facilitating re-authoring conversations, fostering communities of support, and creating therapeutic documents. The Art of Narrative Psychiatry addresses mental health challenges that range from mild to severe, including anxiety, depression, despair, anorexia/bulimia, perfectionism, OCD, trauma, psychosis, and loss. True to form, the author narrates her own experience throughout, sharing her internal thoughts and decision-making processes as she listens to patients. The Art of Narrative Psychiatry is necessary reading for any professional seeking to empower their patients and become a better, more compassionate clinician.
The Emperor's new drugs: an analysis of antidepressant medication data
submitted to the U.S. Food and Drug Administration. Prevention & Treatment, 5(1)
. Kirsch I and Scoboria A (2001). Apples, oranges, and placebos: heterogeneity
in a ...
Author: Fabrizio Benedetti
Publisher: OUP Oxford
One of the most widespread words in medicine is placebo and placebo effect, although it is not always clear what it means exactly. Recent progress in biomedical research has allowed a better clarification of the placebo effect. We know that this is an active psychobiological phenomenon which takes place in the patient's brain and that is capable of influencing both the course of a disease and the response to a therapy. Since publication of the first edition of this book in 2008, there has been an explosion of placebo research, and this new edition brings the topic fully up to date. Throughout, the book emphasizes that there are many placebo effects and critically reviews them in different medical conditions, such as neurological and psychiatric disorders, cardiovascular and respiratory diseases, immune and hormonal responses, as well as oncology, surgery, sports medicine and acupuncture. The psychosocial context around the patient is crucial to the placebo effect, for example the doctor's words and attitudes, and throughout this is considered. Exhaustive in its coverage, and written by a world authority in the field, this is the definitive reference text to the placebo effect - one that is essential for researchers and clinicians across a wide range of medical specialities.
But then he goes on to speculate, like Irving Kirsch in The Emperor's New Drugs,
that what they are really responding to could be an activated placebo effect. If
psychoactive drugs are not all they're cracked up to be—and the evidence is that
Author: Dean Starkman
Publisher: Columbia University Press
Category: Business & Economics
An anthology Malcolm Gladwell has called "riveting and indispensable," The Best Business Writing is a far-ranging survey of business's dynamic relationship with politics, culture, and life. This year's selections include John Markoff (New York Times) on innovations in robot technology and the decline of the factory worker; Evgeny Morozov (New Republic) on the questionable value of the popular TED conference series and the idea industry behind it; Paul Kiel (ProPublica) on the ripple effects of the ongoing foreclosure crisis; and the infamous op-ed by Greg Smith, published in the New York Times, announcing his break with Goldman Sachs over its trading practices and corrupt corporate ethos. Jessica Pressler (New York) delves into the personal and professional rivalry between former spouses and fashion competitors Tory and Christopher Burch. Peter Whoriskey (Washington Post) exposes the human cost of promoting pharmaceuticals for off-label uses. Charles Duhigg and David Barboza (New York Times) investigate Apple's unethical labor practices in China. Max Abelson (Bloomberg) reports on Wall Street's amusing reaction to the diminishing annual bonus. Mina Kimes (Fortune) recounts the grisly story of a company's illegal testing—and misuse—of a medical device for profit, and Jeff Tietz (Rolling Stone) composes one of the most poignant and comprehensive portraits of the financial crisis's dissolution of the American middle class.