The text presents the perspectives and a global look at plasma proteins; well-characterized major proteins; and integrated systems of plasma proteins. The emphasis of the studies is mainly on human proteins.
Author: Frank W Putnam
The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume II describes the plasma proteins in a systematic and integrated way, with emphasis on structure, function, and genetic control. The text presents the perspectives and a global look at plasma proteins; well-characterized major proteins; and integrated systems of plasma proteins. The emphasis of the studies is mainly on human proteins. Clinical relevance is introduced in terms of principles rather than detail. Biochemists, molecular biologists, physiologists, and laboratory researchers in the field of medicine will find the book useful.
Topics covered include: introduction to blood components and blood plasma proteins blood plasma protein domains, motifs and repeats blood plasma protein families and posttranslational modifications blood coagulation and fibrinolysis the ...
Author: Johann Schaller
Publisher: John Wiley & Sons
Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include: introduction to blood components and blood plasma proteins blood plasma protein domains, motifs and repeats blood plasma protein families and posttranslational modifications blood coagulation and fibrinolysis the complement system the immune system enzymes inhibitors lipoproteins hormones cytokines and growth factors transport and storage The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure. Attractively presented in full colour, Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.
This book will be of great value to molecular biologists, physiologists, pathologists, and clinicians.
Author: Frank Putnam
The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume V explores the contribution of molecular biology and gene cloning approaches to the advancement of plasma protein structure, function, and genomic organization studies. This volume is composed of five chapters and begins with a discussion on the DNA sequences and chromosomal location of plasma protein genes, specifically the cloning and sequencing of immunoglobulin genes. These topics are followed by a discussion on the advances in relation to discovered genetic variants present either as normal phenotypes or in dyslipoproteinemic states associated with cardiovascular disease. A chapter highlights the application of molecular biology techniques to the study of gene structure and the translational and maturation steps of every major plasma apolipoprotein. Another chapter emphasizes the unique features of protein structure and the conformational changes that characterize the assembly of macromolecular complexes in plasma and on cell surfaces. The concluding chapter provides a comprehensive review of the integration of molecular biology, physiology, and pathology of plasma proteins and their response in inflammation. This book will be of great value to molecular biologists, physiologists, pathologists, and clinicians.
Author: National Heart, Lung, and Blood InstitutePublish On: 1978
ROIHL - 18249-04 Isolation and identification of platelet RODHL - 18672-03
Dynamic studies of clot structure ROSHL - 09163-13 ... ( rabbits , human )
thrombosis - Structure and function of plasma coagulation program - Human
coumarin - induced prothrombin ROIHL ... of research in thrombosis -
Mathematical models of blood coagulation kinetics ** ROIHL - 16238-05 Protein
structure in coagulation and ...
A chapter describes the plasma protein fractionation. The remaining chapters introduce the clinical relevance of the plasma proteins. This book will be of great value to biologists, geneticists, clinicians, and researchers.
Author: Frank Putnam
The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume III is an eight-chapter treatise that describes the plasma proteins in a systematic integrated manner. This book presents first the perspectives and global outlook at plasma proteins, followed by a series of chapters on the well-characterized major proteins, with particular emphasis on immunoglobulins. Other chapters are devoted to the integrated systems of plasma proteins, especially their structure, function, and genetic control. A chapter describes the plasma protein fractionation. The remaining chapters introduce the clinical relevance of the plasma proteins. This book will be of great value to biologists, geneticists, clinicians, and researchers.
... proteins in plasma Beta cell activation in hypogammaglobulinemias ( human )
** ROIGM - 32111-02 Activation human ... General clinical research center - Structure and function of blood proteins ** P30AM - 26659-04 0040
Establishment of ...
This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use.
Author: Victor M. Rosenoer
Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed. This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism. This monograph should be a useful resource for biochemists and clinicians.
Author: Icie Gertrude Macy HooblerPublish On: 1951
Singly or in combination , values for different blood components may give a
measure of the ability of the organism to maintain normal function in the face of
changing structure , function and environment whether during health or disease .
peaks , each of which was believed to be representative of one or more of the
lysyl or arginyl peptides of the protein structure . The application of this approach
to normal and abnormal human y - globulins , as described in Chapter 18 , led to
This book presents current research in the study of the structure, functions and health impacts of serum albumin.
Author: Robert J. Alekseev
Publisher: Nova Science Pub Incorporated
Serum albumin is the most abundant plasma protein in mammals. Albumin is essential for maintaining the osmotic pressure needed for proper distribution of body fluids between intravascular compartments and body tissues. It also acts as a plasma carrier by non-specifically binding several hydrophobic steroid hormones and as a transport protein for hemin and fatty acids. This book presents current research in the study of the structure, functions and health impacts of serum albumin. Topics include the catalytic activities of serum albumin; the interaction of serum albumin with anesthetics; microparticulate drug delivery systems based on serum albumin; hydration of human serum albumin and extracting physical properties of serum albumin using osmotic pressure.
At the present time , the technique has been used only to study plasma protein
secretion by a global population of ... Their synthesis , turnover and biological
significance ; in Allison AC ( ed ) : Structure and Function of Plasma Proteins .
Category: Clinical enzymology
"The Erti-Karger table system" (13 p.) inserted in pocket at end of v. 12, no. 1.
Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to
Author: Roger L. Lundblad
Publisher: CRC Press
The fractionation of human blood plasma can be considered to be a mature industry, with the basic technology, alcohol fractionation, dating back at least to the 1940s. Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to
This book serves as an introduction to protein structure and function.
Author: Engelbert Buxbaum
This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine and related courses. About the author: Dr. Buxbaum is a biochemist with interest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.
Protein Structure - Function Relationship Proceedings of the International
Symposium on Protein StructureFunction Relationship , and of the Protein ...
Relation between Structure of Plasma Proteins and their Metal Complexes ( 15 p
. ) , 8 .
Author: Center for Blood Research (Boston, Mass.)Publish On: 1979
Fragments of Serum Albumin Fragments of albumin prepared by limited
proteolysis provide independent evidence for the ... ( 6 ) Brown , J. R. , Structure
and evolution of serum albumin , in Albumin : Structure , Biosynthesis , Function ,
T. Peters ...
Virgil L. Koenig , Ph.D. Lens proteins ; urinary gonadotropin ; protein
characterization . Alexander Kurosky , Ph.D. Structure , function , and evolution of plasma proteins and enterobacterial toxins . Edward F. LaBelle , Ph.D. Function
of proteins ...
Given the central role of plasma proteins in maintaining intracellular and
extracellular homeostasis , further definition of the secretory process is vital to the
clinician ' s ... The Plasma Proteins : Structure , Function and Genetic Control , Vol
Author: David Zakim
Publisher: W B Saunders Company
A thoroughly revised edition by expert contributors presents definitive coverage of liver disease. This state-of-the-art text has been reorganized into two stand-alone volumes--the first volume deals with the basic sciences of biochemistry, physiology, and pathophysiology while the second is completely devoted to clinical issues. New chapters cover metabolism of collagen, autoimmune liver disease, clinical pharmacology of anti-viral agents, and AIDS and the liver.