Author: Jessica Wornham

Publisher:

ISBN: OCLC:1287090976

Category: Knee

Page: 72

View: 990

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Current literature is dated or spread across many research articles. This volume will include different sources of adult stem cells, cell derived biological agents, stem cell derived exomes, secretion factors and more.

Author: Yin Xiao

Publisher: Academic Press

ISBN: 0128219971

Category: Science

Page: 300

View: 651

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Stem Cell Therapy for Osteoarthritis delivers state-of-the-art knowledge of current stem cell therapies for osteoarthritis. Current literature is dated or spread across many research articles. This volume will include different sources of adult stem cells, cell derived biological agents, stem cell derived exomes, secretion factors and more. In addition to covering current therapies and technologies, the authors summarize methodologies, applications and the inclusion/exclusion criteria. The authors are world-renown experts in the field and this book fills a gap in the market. Introduces the latest updates and technologies in stem cell therapy for osteoarthritis Covers mechanisms, stem cell-based products, clinical trials, current challenges and much more Written for academic researchers, to PhD students, medical doctors, including rheumatologists and orthopaedic surgeons, other physicians and nurses

And that's exciting for those of us who are in the Boomer demographic.In this volume I also discuss other forms of knee pain that will shed light on how difficult the diagnosis can be in certain instances.I have also updated information on ...

Author: Nathan Wei

Publisher:

ISBN: 1503017486

Category:

Page: 96

View: 540

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Osteoarthritis is the most common form of arthritis... but like Rodney Dangerfield, it doesn't get much respect. The reason is that it is so hard to treat.The types of management techniques used haven't changed in almost forty years. Very few pharmaceutical and biotech companies are willing to tackle osteoarthritis because it is such a difficult task. The number of clinical trials involving new therapies for osteoarthritis is riddled with the bodies of the fallen.For those of us in clinical practice, it has been a frustrating experience... until now...The initial volume The Book On Stem Cells For Osteoarthritis was a compilation of articles I had written on the subject of mesenchymal stem cells in the earlier days of our experience with this technology. The impetus for the first volume was to provide readers instant access to all the articles I had written on the topic rather than having to click their way through the internet. While the first book- really a booklet- was received with a lot of enthusiasm, it was clear there was also a lot of repetitive information. Unfortunately, that is the nature of a compilation of articles... there is much repetitive information.I believe the key thing is that the information is good. It is understandable. And repetition is not necessarily a bad thing when it comes to understanding knee osteoarthritis and the options available for treatment. There have been new developments in our understanding of this condition, particularly when it comes to the knee. And that's exciting for those of us who are in the Boomer demographic.In this volume I also discuss other forms of knee pain that will shed light on how difficult the diagnosis can be in certain instances.I have also updated information on stem cell biology.As the reader might imagine, the science is constantly evolving. The same is true for the procedures themselves.If the goal is to delay or even eliminate the need for joint replacement, the optimal procedure for the application of stem cell therapy is going to go through a series of improvements with the passage of time.

Stem cell therapy has emerged as a new direction in the field of regenerative medicine.

Author: Shyamal Kanti Guha

Publisher: LAP Lambert Academic Publishing

ISBN: 3659695610

Category:

Page: 76

View: 197

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Stem cell therapy has emerged as a new direction in the field of regenerative medicine. Hundreds of workers throughout the world continue to refine and explore the role of bone marrow and cord blood stem cells for their regular use to solve hematological and immune mediated disorders since many years. Many of them are working to explore the uses of the different types of adult mesenchymal stem cells found in bone marrow and cord blood that could be corrected by replacing cells in the damaged tissues in their own lineages. In recent years stem cell research is being pursued in the hope of achieving major medical breakthroughs. Scientists are striving to create therapies that rebuild or replace damaged cells with tissues grown from stem cells and offer hope to people suffering from cancer, diabetes, cardiovascular disease, spinal-cord injuries, and many other neurodegenerative disorders. Both adult and embryonic stem cells may also provide a route for scientists to develop valuable new methods of drug discovery and testing.

Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue ...

Author: Phuc Van Pham

Publisher: Springer

ISBN: 9783319401447

Category: Science

Page: 315

View: 702

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This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

This book introduces many new technologies and clinical applications of hematopoietic stem cells and mesenchymal stem cell transplantation for the treatment of autoimmune diseases and inflammatory diseases.

Author: Phuc Van Pham

Publisher: Springer

ISBN: 9783030234218

Category: Science

Page: 163

View: 139

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This book introduces many new technologies and clinical applications of hematopoietic stem cells and mesenchymal stem cell transplantation for the treatment of autoimmune diseases and inflammatory diseases. Presented in two parts, Part 1 focuses on stem cell therapies for autoimmune disease treatment; Part 2 focuses on stem cell therapies and their application in the treatment of common inflammatory diseases, including chronic knee osteoarthritis, chronic obstructive pulmonary disease, liver cirrhosis, Crohn's Disease, Multiple Sclerosis, and more. This book is an essential source for all advanced students and researchers involved with these diseases, stem cells, or both. Stem Cell Transplantation for Autoimmune Diseases and Inflammation and the other books in the Stem Cells in Clinical Applications series are invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine, or tissue engineering as well as cancer or genetics research.

Une monographie (en anglais) consacrée au PRP (Plasma Riche en Plaquettes) et thérapies cellulaires : les applications médicales, la fabrication, le fonctionnement, la standardisation et les études menées à ce jour avec les résultats ...

Author: Collectif

Publisher: Favre

ISBN: 9782828912086

Category: Science

Page: 94

View: 446

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Une monographie (en anglais) consacrée au PRP (Plasma Riche en Plaquettes) et thérapies cellulaires : les applications médicales, la fabrication, le fonctionnement, la standardisation et les études menées à ce jour avec les résultats. La médecine régénérative englobe un large éventail de techniques ayant pour but de réparer, voire remplacer, les tissus endommagés ou âgés. Le plasma riche en plaquettes (PRP) autologue représente l'approche de médecine régénérative la plus simple. Cette technique est basée sur les capacités intrinsèques du corps humain à réparer une lésion tissulaire. L'intérêt croissant qu'elle suscite s'explique à la fois par le fait qu'elle représente une alternative sûre et naturelle à d'autres formes de traitement plus invasives et par les résultats prometteurs qu'elle a démontrés jusqu'à maintenant pour un grand nombre d'indications. Le plasma riche en plaquettes (abréviation PRP), ou plasma riche en facteurs de croissance (abréviation PRGF) est du plasma sanguin enrichi en plaquettes par une centrifugation. Le PRP est une source concentrée de plaquettes autologues. Il contient et relâche par dégranulation différents facteurs de croissance et cytokines capables de stimuler la régénération de certains tissus. Il est ainsi utilisé dans de nombreuses indications médicales et esthétiques. Si le PRP est en train de devenir un acteur incontournable dans le monde médical, certaines limitations liées à un manque de procédure standardisée pour sa préparation rendent difficile la comparaison entre les données cliniques disponibles. La technologie développée par Regen Lab SA s'impose actuellement comme la seule capable d'apporter une solution à ce défi de standardisation des préparations de cellules fraîches. Sur la base d'une expérience de plus de 10 ans, ce livre a été conçu par Regen Lab SA afin d'aider les professionnels impliqués dans la médecine régénérative à mieux comprendre et utiliser le PRP. Il est en en premier lieu destiné aux médecins qui exercent et conduisent des recherches dans des disciplines où les thérapies avec le PRP représentent une option thérapeutique, mais il s'adresse également à quiconque recherchant des informations fiables et à jour sur cette technologie. ----- In the 60's, a scientist called Doctor Leonard Hayflick (Wistar Institute, Philadelphia) carefully characterized the serial cultivation of primary human fibroblast cell by demonstrating that primary human cell strains have a limited replicative lifespan or "doubling potential", restricted to 40-50 divisions. This finding led to the hypothesis that oxidative damage could be partially responsible for limiting in vitro lifespan, consistent with the free radical hypothesis of aging. We now know that senescence in response to repeated passage occurs because of critical shortening of the telomeres. The Hayflick theory has been greatly reconsidered by the observations from the INSERM group of Dr Barlovatz-Meimon published in 2003 in Paris regarding in vivo (i.e. on the patient himself) cell growth. These studies hypothesized that the fibroblasts may reach a 2 to 3 log growth, meaning that they could potentially undergo up to 500 to 5'000 cell divisions. Our GMP class II and III medical devices fully guarantee the patient's safety because they are non-pyrogenic. Moreover, our manufacture process respects a full compliance with the new European Medical Device Regulation (MDR) June 2017, FDA (USA), and CFDA Regulations. For all these reasons, we believe that we bring to the medical community a powerful and reliable tool to standardize PRP preparations and thus future cell therapy clinical outcomes.

The range of therapeutic applications is wide, including cardiac insufficiency, atherosclerosis, cartilage defects, bone repair, burns, diabetes and liver or bladder regeneration.This book, whilst not covering all aspects

Author: J. F. Stoltz

Publisher: IOS Press

ISBN: 9781614990758

Category: Medical

Page: 464

View: 298

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Most human tissues do not regenerate spontaneously. Cell therapy and tissue engineering, which involve collecting cells from either the patient or a donor and introducing them into injured tissues or organs, sometimes after modifying their properties, offer promising solutions for regenerative medicine. Indeed, so promising are these therapies that current research has shifted from organ growth to cell therapy. The range of therapeutic applications is wide, including cardiac insufficiency, atherosclerosis, cartilage defects, bone repair, burns, diabetes and liver or bladder regeneration.This book, whilst not covering all aspects

This book covers in detail some existent theories and innovative concepts revolving around developments in the field of stem cell research.

Author: Rex Turner

Publisher:

ISBN: 1632414120

Category: Medical

Page: 0

View: 410

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Stem cells are found in multicellular organisms. They have two broad categories - embryonic stem cells and adult stem cells. They are generally found in undifferentiated form and can be transformed into specialized cells. In adults, they act as a repair system of the body. These cells are frequently used in medical therapies such as bone marrow transplant, etc. The viability of stem cell therapy is being investigated to treat diseases such as cancer, diabetes, rheumatoid arthritis, osteoarthritis, vision impairment, parkinson's disease, impaired hearing, etc. This book covers in detail some existent theories and innovative concepts revolving around developments in the field of stem cell research. It is an upcoming field of medical science that has undergone rapid development over the past few decades. This text aims to bring forth studies related to all the significant aspects of stem cells along with technological progress that will have future implications. For all those who are interested in this area of study, this book can prove to be an essential guide.

This book represents an updated overview on selected topics related to mesenchymal stem cells as well as induced pluripotent stem cells.

Author: Khalid Ahmed Al-Anazi

Publisher: BoD – Books on Demand

ISBN: 9781789238075

Category: Science

Page: 150

View: 782

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This book represents an updated overview on selected topics related to mesenchymal stem cells as well as induced pluripotent stem cells. The book is divided into three main sections that cover several topics including: sources of both stem cell types, their preparation and general properties, as well as their therapeutic indications and clinical utilization with particular attention given to their use in infectious diseases, osteoarthritis, as well as immunological disorders.