Author: International Agency for Research on CancerPublish On: 2018-07-27
This volume of the IARC Monographs provides evaluations of the carcinogenicity of: N,N-dimethylformamide, a solvent produced in high volumes and commonly used in many industrial processes; 2-mercaptobenzothiazole, a rubber accelerant and ...
Author: International Agency for Research on Cancer
Publisher: International Agency for Research on Cancer
ISBN: 9283201531
Category: Medical
Page: 0
View: 225
This volume of the IARC Monographs provides evaluations of the carcinogenicity of: N,N-dimethylformamide, a solvent produced in high volumes and commonly used in many industrial processes; 2-mercaptobenzothiazole, a rubber accelerant and preservative; the rocket fuel hydrazine; the widely used fire retardant tetrabromobisphenol A; 1-bromopropane, a solvent used in dry cleaning, degreasing and adhesive resins; the seed fumigant 3-chloro-2-methylpropene; and N,N-dimethyl-p-toluidine, a hardening agent in dental and bone adhesives. Exposure to all seven agents considered may occur in the general population as well as in different occupational settings. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of environmental or occupational exposure to these agents.
Author: International Agency for Research on CancerPublish On: 1995
Dry cleaning is evaluated in the first and most extensive monograph. Concerning exposures to specific chemicals, tetrachloroethylene is identified as the most commonly used solvent during the last two to three decades.
Author: International Agency for Research on Cancer
Publisher: IARC Monographs on the Evaluat
ISBN: UOM:39015036046525
Category: Medical
Page: 576
View: 333
Evaluates the carcinogenic risks to humans posed by exposures in the dry cleaning industry by eight chlorinated solvents and related chemicals and by an additional group of seven industrial chemicals. Dry cleaning is evaluated in the first and most extensive monograph. Concerning exposures to specific chemicals, tetrachloroethylene is identified as the most commonly used solvent during the last two to three decades. The evaluation also considers exposure to the wide range of chemicals used in the treatment of spots. A review of epidemiological studies on dry cleaning indicates that the risks for cancers at two cites, urinary bladder and esophagus, may be increased by employment in dry cleaning. The monograph concludes that dry cleaning entails exposures that are possibly carcinogenic to humans. A second group of monographs evaluates selected chlorinated solvents and related chemicals used in dry cleaning, metal cleaning, and degreasing as chemical intermediates and in the production of insecticides and herbicides. Trichloroethylene, tetrachloroethylene, and 1 2 3-trichloropropane were classified as probably carcinogenic to humans. 1-Chloro-2-methylpropene was classified as possibly carcinogenic to humans. The remaining chemicals - chloral and chloral hydrate, dichloroacetic acid, trichloroacetic acid, and 3-chloro-2-methylpropene - could not be classified. For the remaining seven chemicals used in a diversity of industrial applications, vinyl fluoride was classified as probably carcinogenic to humans. Furan, benzofuran, and vinyl acetate were classified as possibly carcinogenic to humans. Acrolein crotonaldehyde and furfural could not be classified.