Protein Structure Prediction A Practical Approach

Protein Structure Prediction   A Practical Approach

This book presents practical computer-based methods using the latest computer modelling algorithms. -

Author: Michael J. E. Sternberg

Publisher: Oxford University Press, USA

ISBN: 9780191588990

Category:

Page: 318

View: 208

The three-dimensional structure of proteins is a key factor in their biological activity. There is an increasing need to be able to predict the structure of a protein once its amino-acid sequence is known; this book presents practical methods of achieving that ambitious aim, using the latest computer modelling algorithms. - ;The prediction of the three-dimensional structure of a protein from its sequence is a problem faced by an ever-increasing number of biological scientists as they strive to utilize genetic information. The increasing sizes of the sequence and structural databases, the improvements in computing power, and the deeper understanding of the principles of protein structure have led to major developments in the field in the last few years. This book presents practical computer-based methods using the latest computer modelling algorithms. -
Categories:

Bioinformatics Sequence Structure and Databanks

Bioinformatics  Sequence  Structure and Databanks

Finally, there are chapters on multiple sequence alignment and protein secondary structure prediction. Bioinformatics will be invaluable to occasional users of these techniques as well as experienced professionals or researchers.

Author: Des Higgins

Publisher: OUP Oxford

ISBN: 9780191566011

Category: Science

Page: 270

View: 642

Bioinformatics covers practical important topics in the analysis of protein sequences and structures. It includes comparing amino acid sequences to structures comparing structures to each other, searching information on entire protein families as well as searching with single sequences, how to use the Internet and how to set up and use the SRS molecular biology database management system. Finally, there are chapters on multiple sequence alignment and protein secondary structure prediction. Bioinformatics will be invaluable to occasional users of these techniques as well as experienced professionals or researchers.
Categories: Science

Protein Structure Prediction

Protein Structure Prediction

This thorough new edition explores web servers and software for protein structure prediction and modeling that are freely available to the academic community.

Author: Daisuke Kihara

Publisher: Humana

ISBN: 1071607073

Category: Science

Page: 358

View: 754

This thorough new edition explores web servers and software for protein structure prediction and modeling that are freely available to the academic community. Taking into account the numerous advances in the computational protein structure prediction/modeling field, the book includes residue-contact prediction via deep learning, a wide variety of protein docking models, as well as cryo-electron microscopy (cryo-EM) techniques. Written by renowned experts in the field and for the highly successful Methods in Molecular Biology series, chapters include the kind of key detail and implementation advice necessary for researchers to achieve optimal results in their own work. Authoritative and fully updated, Protein Structure Prediction, Fourth Edition is a practical and immediately useful guide for biology researchers working toward modeling protein structures./div/div/div/div/div/div/div/div/div/div/div/div/div/div/div/div/divdiv
Categories: Science

Protein Structure Prediction

Protein Structure Prediction

In Protein Structure Prediction: Methods and Protocols, world-class investigators detail their most successful methods-and the theory behind them-for delineating the shape, form, and function of proteins.

Author: David M. Webster

Publisher: Springer Science & Business Media

ISBN: 9781592593682

Category: Science

Page: 422

View: 910

The deeper understanding of protein structure now emerging from cutting-edge research is not only illuminating evolutionary and biochemical mechanisms, but also promises enormous ramifications for molecular medicine, as well as for biotechnology, biophysics, biology, genetics, and other molecular sciences. In Protein Structure Prediction: Methods and Protocols, world-class investigators detail their most successful methods-and the theory behind them-for delineating the shape, form, and function of proteins. The protocols range from basic to advanced and include sequence alignment, the prediction of transmembrane protein structure, and the development of suitable folding potentials. There are also techniques for receptor site prediction, the identification of motifs and domains, the comparative modeling of proteins, the docking of peptides and ligands, and ab initio approaches to protein loop and side-chain prediction. To ensure robust and successful experimental results, each protocol contains step-by-step instructions, as well as tips on pitfalls to avoid and how procedures may be optimized for different systems. Comprehensive, accessible, and highly practical, Protein Structure Prediction: Methods and Protocols offers protein researchers, structural biologists, and other investigators a critical synthesis of the latest research results, as well as the vital guidance needed to understand the structure and interaction of proteins and peptides.
Categories: Science

A Practical Guide to Protein Engineering

A Practical Guide to Protein Engineering

There are many bioinformatics tools that predict the secondary structures of proteins. In our experience, secondary structure prediction is particularly useful in situations when: 5 We need to determine if a point mutation introduced ...

Author: Tuck Seng Wong

Publisher: Springer Nature

ISBN: 9783030568986

Category: Science

Page: 202

View: 850

This textbook introduces readers in an accessible and engaging way to the nuts and bolts of protein expression and engineering. Various case studies illustrate each step from the early sequence searches in online databases over plasmid design and molecular cloning techniques to protein purification and characterization. Furthermore, readers are provided with practical tips to successfully pursue a career as a protein engineer. With protein engineering being a fundamental technique in almost all molecular biology labs, the book targets advanced undergraduates and graduate students working in molecular biology, biotechnology and related scientific fields.
Categories: Science

Modern Protein Chemistry

Modern Protein Chemistry

Practical Aspects Gary C. Howard, William E. Brown ... RECOMMENDED READING Sternberg, M. J. E., Ed., Protein Structure Prediction: A Practical Approach, IRL Press, Oxford, 1996. Vásquez, M., Némethy, G., and Scheraga, H.A., ...

Author: Gary C. Howard

Publisher: CRC Press

ISBN: 9781420036527

Category: Medical

Page: 272

View: 356

In recent years, interest in proteins has surged. This resurgence has been driven by the expansion of the post-genomic era when structural genomics and proteomics require new techniques in protein chemistry and new applications of older techniques. Protein chemistry methods are used by nearly every discipline of biomedical research. Many techniques
Categories: Medical

Protein Structure Prediction

Protein Structure Prediction

While most textbooks on bioinformatics focus on genetic algorithms and treat protein structure prediction only superficially, this course book assumes a novel and unique focus.

Author: Anna Tramontano

Publisher: John Wiley & Sons

ISBN: 9783527311675

Category: Medical

Page: 228

View: 499

While most textbooks on bioinformatics focus on genetic algorithms and treat protein structure prediction only superficially, this course book assumes a novel and unique focus. Adopting a didactic approach, the author explains all the current methods in terms of their reliability, limitations and user-friendliness. She provides practical examples to help first-time users become familiar with the possibilities and pitfalls of computer-based structure prediction, making this a must-have for students and researchers.
Categories: Medical

Introduction to Computational Proteomics

Introduction to Computational Proteomics

Proteins 54, 41–48. Creighton, T. E. (1992). “Proteins: structures and molecular properties.” WH Freeman, New York. Sternberg, M. J. E., ed. (1996) “Protein structure prediction: a practical approach.” Oxford University Press.

Author: Golan Yona

Publisher: CRC Press

ISBN: 9781000738278

Category: Mathematics

Page: 767

View: 799

Introduction to Computational Proteomics introduces the field of computational biology through a focused approach that tackles the different steps and problems involved with protein analysis, classification, and meta-organization. The book starts with the analysis of individual entities and works its way through the analysis of more complex entitie
Categories: Mathematics

A Metaheuristic Approach to Protein Structure Prediction

A Metaheuristic Approach to Protein Structure Prediction

505–516 (1999) Dill, K.A.: Theory for the folding and stability of globular proteins. Biochemestry 24(6), 1501–1509 (1985) Li, ... simple model of protein folding. ... Differential Evolution: A Practical Approach to Global Optimization.

Author: Nanda Dulal Jana

Publisher: Springer

ISBN: 9783319747750

Category: Technology & Engineering

Page: 220

View: 796

This book introduces characteristic features of the protein structure prediction (PSP) problem. It focuses on systematic selection and improvement of the most appropriate metaheuristic algorithm to solve the problem based on a fitness landscape analysis, rather than on the nature of the problem, which was the focus of methodologies in the past. Protein structure prediction is concerned with the question of how to determine the three-dimensional structure of a protein from its primary sequence. Recently a number of successful metaheuristic algorithms have been developed to determine the native structure, which plays an important role in medicine, drug design, and disease prediction. This interdisciplinary book consolidates the concepts most relevant to protein structure prediction (PSP) through global non-convex optimization. It is intended for graduate students from fields such as computer science, engineering, bioinformatics and as a reference for researchers and practitioners.
Categories: Technology & Engineering

Molecular Biology and Biotechnology

Molecular Biology and Biotechnology

Protein secondary and tertiary structure prediction is often difficult to do correctly and indeed in reality an active protein may have a range of conformations. Books such as Protein Structure Prediction – A Practical Approach" and ...

Author: John M Walker

Publisher: Royal Society of Chemistry

ISBN: 9781847551498

Category: Science

Page: 588

View: 890

As a textbook, Molecular Biology and Biotechnology has always been immensely popular. Now in its fourth edition, it has been completely revised and updated to provide a comprehensive overview and to reflect all the latest developments in this rapidly expanding area. Written by recognised experts, the book aims to identify the impact that molecular biology has had on the development of biotechnology, with each of the nineteen chapters describing a specific subject area relevant to the subject. The impressive breadth of coverage includes areas such as plant biotechnology; food technology; vaccine development; the production of transgenic plants and animals; and the addition of an appropriate and timely new chapter devoted to bioinformatics. Presenting information in an easily assimilated form, Molecular Biology and Biotechnology makes an ideal undergraduate text. It will be of particular interest to students of biology and chemistry, as well as to scientists from outside the field requiring a rapid introduction to the subject.
Categories: Science