Obesity and Syndrome X

Obesity and Syndrome X

We hope this book will not only expand the practice in the coming years, but that it will create new avenues for future research as well.

Author: Mithun Das

Publisher:

ISBN: 1536146706

Category: HEALTH & FITNESS

Page: 318

View: 387

Obesity is a major risk for both cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Obesity has reached epidemic proportions globally, and evidence suggests that the situation is likely to get worse in both developed and developing countries. It is considered to be a predisposing factor for several chronic diseases which include CVD, ischemic stroke, hypertension, T2DM, vascular dysfunction, and proinflammatory and prothrombotic state. This is where Syndrome X intersects with obesity and plays the role of a common denominator for CVD and T2DM. Persons with Syndrome X are more susceptible to CVD & T2DM.It is particularly relevant to recognize that variation in disease susceptibility among individuals in the population at large is a consequence of the intersection of the distribution of genotypes with the distribution of past environmental exposures and future environmental trajectories. For instance, many individuals who have a genotype that is found in those with disease will remain healthy because of the compensatory effects of a different environmental history on the same initial conditions. Similarly, individuals who do not have a high risk genotype may develop a disease of an adverse environmental history. That is, interaction between a particular genotype and particular environmental exposures.In the thrifty genotype hypothesis as proposed by Neel (1962), entire populations have an increased predisposition to T2DM due to genetic selection. They are better adapted to different nutritional circumstances than those they experience today. In the thrifty phenotype hypothesis (also known as Barker's Hypothesis), maladaptive responses occur as a result of environmentally induced alteration of physiology in the early life of the individual. Both hypotheses offer explanations of why the frequency of diabetes and obesity may differ in different populations and why predisposition to diabetes is common, albeit by very different mechanisms. A third hypothesis called the "common soil" hypothesis as mentioned by Lebovitz (2006) that diabetes and CVD might share an underlying cause(s) is also described. Insulin resistance is central both to the progression from normal glucose tolerance to T2DM and to a constellation of CVD risk factors known as Syndrome X or Metabolic Syndrome. Then there is the epigenome that directly impacts gene expression and can be modified by both genetic and environmental factors. It is the potentially heritable changes in gene expression that does not involve changes to the underlying DNA sequences - a change in phenotype without a change in genotype. The epigenoytpe is dynamic and varies over time and tissues as a result of environmental exposure, aging, and diseases and other factors.The present book is an assembly of the vast knowledge that has been generated over the last decade worldwide in the field of obesity and metabolic syndrome related disorders, and an attempt to translate research findings into a clinically useful tool for better diagnosis, intervention, and prevention of this global public health burden. We hope this book will not only expand the practice in the coming years, but that it will create new avenues for future research as well.
Categories: HEALTH & FITNESS

Insulin Resistance

Insulin Resistance

The first authoritative book on the subject, Insulin Resistance: The Metabolic Syndrome X illuminates the special importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome.

Author: Gerald M. Reaven

Publisher: Springer Science & Business Media

ISBN: 0896035883

Category: Medical

Page: 374

View: 200

In Insulin Resistance: The Metabolic Syndrome X, outstanding investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia (Syndrome X) play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization-as well as polycystic ovary disease. Under the aegis of Gerald Reaven, the discoverer of Syndrome X, the distinguished authorities writing here detail for the first time the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Each author has been encouraged to present a point of view that reflects their unique insights. The first authoritative book on the subject, Insulin Resistance: The Metabolic Syndrome X illuminates the special importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome. Its thoughtful and detailed approach will make it an essential reference for basic and clinical researchers seeking to understand these critical phenomena.
Categories: Medical

Syndrome X

Syndrome X

According to the 1994 NHANES III figures, a whopping 50 percent of Americans
are overweight, some 22 percent of those between the ages of twenty and
seventy-four are obese, ... It certainly increases the risk of Syndrome X, but that's
not all.

Author: Gerald M. Reaven

Publisher: Simon and Schuster

ISBN: 9780684868622

Category: Health & Fitness

Page: 284

View: 816

Describes the cluster of metabolic abnormalities known as Syndrome X and offers a program of diet and exercise intended to lower the risk of heart attacks and heart disease caused by Syndrome X.
Categories: Health & Fitness

Syndrome X

Syndrome X

Syndrome X is the first book to tell you how to fight the epidemic disorder that is derailing the health of nearly a third of North Americans.

Author: Jack Challem

Publisher: Wiley

ISBN: 0471398586

Category: Health & Fitness

Page: 288

View: 237

You can feel great again! "Syndrome X proactively lays out a nutritious, tasty, and simple diet plan to get us back to the basics of healthy nutrition."-Lendon H. Smith, M.D., New York Times bestselling author of Feed Your Body Right "Syndrome X is the best new book to help you understand the facts about nutrition, health, and aging. . . . It is full of new information and insights most readers have never had access to before. Everyone who values his or her health will want to read the book and then individualize the program to suit his or her needs-the authors have made this easier than ever to do."-Richard A. Kunin, M.D., author of Mega-Nutrition What is Syndrome X? It's a resistance to insulin-the hormone needed to burn food for energy-combined with high cholesterol or triglycerides, high blood pressure, or too much body fat. Syndrome X ages you prematurely and significantly increases your risk of heart disease, hypertension, obesity, eye disease, nervous system disorders, diabetes, Alzheimer's, cancer, and other age-related diseases. Syndrome X is the first book to tell you how to fight the epidemic disorder that is derailing the health of nearly a third of North Americans. It outlines a complete three-step program-including easy-to-follow diets, light physical activity, and readily available vitamins and nutritional supplements-that will safeguard you against developing Syndrome X or reverse it if you already have it.
Categories: Health & Fitness

Genetics of Obesity Syndromes

Genetics of Obesity Syndromes

... Thyroid hormone resistance syndrome 3p24.1 THRB 181450 Ulnar-mammary
(Schinzel) syndrome 12q24.21 TBX3 194072 WAGR syndrome with obesity
11p13 WT1 X-linked 11p13 PAX6 301900 Börjeson-Forssman-Lehmann
syndrome ...

Author: Philip R. Beales

Publisher: Oxford University Press

ISBN: 9780199719860

Category: Medical

Page: 304

View: 733

Obesity is one of the most important contributing factors to disease throughout the world and is an area of great current interest among researchers and clinicians. The genetics of common obesity is complex, and an important thread through this labyrinth is the study of genetic syndromes in which obesity is a major component. By examining the genetic mechanisms of obesity in these syndromes, the authors will shed new light on the genetics of common obesity. This is the first book on this important and exciting new area and addreses both the molecular and clinical features of the obesity syndromes, providing hard-core information for researchers and practical guidelines for clinicians caring for obese patients. The book is divided into three sections: the first covers approaches for assessing and investigating the obese individual; the second describes nondysmorphic, monogenic forms of obesity; and the third documents key, multisystem obesity syndromes with various genetic etiologies. It is as much a reference book as it is a manual and will appeal to clinical geneticists, obesity researchers, endocrinologists, nutritionists, and medical biologists.
Categories: Medical

Handbook of Obesity Volume 1

Handbook of Obesity    Volume 1

552 50.6 Debating the Relevance of Abdominal Obesity as a Key Criterion for
Metabolic Syndrome. ... field of endocrinology and metabolism but also to
cardiovascular medicine when he introduced the notion of syndrome X.1 Reaven
made ...

Author: George A. Bray

Publisher: CRC Press

ISBN: 9781842145579

Category: Medical

Page: 736

View: 710

In recent years, we've developed a much better grasp of the biological and other factors associated with the development of obesity. Reflecting our evolving understanding of causes and consequences, Handbook of Obesity: Epidemiology, Etiology, and Physiopathology provides comprehensive coverage of the biological, behavioral, and environmental deter
Categories: Medical

Obesity

Obesity

In 1988 , Gerald Reaven coined the term " syndrome X ” for a Banting Lecture at
the American Diabetes Association and popularized the concept that a cluster of
findings occur that are related to diabetes and atherosclerosis . Syndrome X ...

Author: Robert H. Eckel

Publisher: Lippincott Williams & Wilkins

ISBN: 0781728444

Category: Medical

Page: 592

View: 337

Written by an international group of leading experts on obesity and related disorders, this volume is the first to address the clinical aspects of obesity. The contributors review the latest clinically relevant findings on the etiology and pathophysiology of obesity, examine the full spectrum of comorbid conditions and complications, and discuss the role of drugs, behavioral interventions, exercise, and surgery in treatment of obesity. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
Categories: Medical

ICD 9 CM Coding Theory and Practice with ICD 10 2013 2014 Edition E Book

ICD 9 CM Coding  Theory and Practice with ICD 10  2013 2014 Edition   E Book

Dysmetabolic Syndrome X is characterized by abdominal obesity, insulin
resistance, dyslipidemia, and elevated blood pressure or hypertension. Patients
with these conditions are considered to be at greater risk for type II diabetes, ...

Author: Karla R. Lovaasen

Publisher: Elsevier Health Sciences

ISBN: 9780323277723

Category: Medical

Page: 832

View: 711

Learn to code effectively with ICD-9-CM medical coding and gain a thorough introduction to ICD-10-CM/PCS coding with one book! ICD-9-CM Coding, 2013/2014 Edition combines basic coding principles with proven, practical insight and the ICD-9-CM and ICD-10-CM/ICD-10-PCS Official Guidelines for Coding and Reporting to prepare you for the upcoming implementation of ICD-10-CM/PCS. Whether you're learning to code for the first time or making the transition from ICD-9-CM to ICD-10-CM/PCS, leading medical coding authors Karla Lovaasen and Jennifer Schwerdtfeger deliver the fundamental understanding you need to succeed in hospital and physician settings. Both ICD-9-CM codes and ICD-10-CM/ICD-10-PCS codes are shown in all coding exercises and examples (including answer keys). Emphasis on ICD-10-CM and ICD-10-PCS coding prepares you for the upcoming implementation of ICD-10. MS-DRG documentation and reimbursement details guide you through this key component of the coding process. Line coding exercises and activities challenge you to apply concepts to solve problems. ICD-10 Official Guidelines for Coding and Reporting (OGCR) are included in each coding chapter, immediately following the ICD-9-CM coding guidelines. Full-color A&P content, disease coverage, procedure guidelines, and drug data ensure that you’re familiar with key topics affecting medical coding. Medical record coverage introduces the records and documents you’ll encounter on the job. Updated Coding Clinic references direct you to the definitive coding resource from the American Hospital Association (AHA). A companion Evolve website provides convenient online access to the OGCR, medical and surgical root operations definitions, a MS-DRG list, partial answer keys, and more.
Categories: Medical

Handbook of Obesity

Handbook of Obesity

Although rare, these mutations are instructive in the sense that the metabolic
sequelae are almost identical to the ''garden-variety'' obesity/syndrome X. 3
Congenital Generalized Lipodystrophy Lamin does not appear to be involved in ...

Author: George A. Bray

Publisher: CRC Press

ISBN: 9780203913376

Category: Medical

Page: 1072

View: 279

Offering perspectives on the history, prevalence and genetics of obesity, this book examines the origins and etiology of obesity. It considers the relationship between behavioural neuroscience and obesity.
Categories: Medical

Nutritional Self Defense

Nutritional Self Defense

Though diabetes and / or obesity may be present , this syndrome is not about
either of those conditions , as the syndrome is typically expressed without
diabetes or obesity . Syndrome X to gain weight . Waist > 40 inches - male ; > 35
inches ...

Author: Lily Splane

Publisher: Anaphase II Publishing

ISBN: 0945962134

Category: Health & Fitness

Page: 344

View: 697

Get a fighting chance with "Nutritional Self-Defense." Readers will find the knowledge and tools to combat the daily onslaught of processed fast-foods, pollution, and stress here with authoritative, up-to-date, tables for instant reference.
Categories: Health & Fitness

Obesity and Mental Disorders

Obesity and Mental Disorders

One such complication of obesity is the metabolic syndrome. It is also known as ''
syndrome X.'' The metabolic syndrome is a grouping of risk factors predisposing
individuals to type 2 diabetes and cardiovascular disease (CVD).

Author: Susan L. McElroy

Publisher: CRC Press

ISBN: 9780849374517

Category: Medical

Page: 488

View: 134

Currently, there are a limited amount of guidelines to help clinicians manage patients with obesity and comorbid mental disorders. This expertly written source fills the gap in the literature by providing a clear overview of obesity and its relationship to mental illness while reviewing the most recent methods to manage and control the condition with diet, exercise, psychological treatments, pharmacotherapy, and surgery.
Categories: Medical

Nutrients Stress and Medical Disorders

Nutrients  Stress and Medical Disorders

Evidence suggests that abdominal obesity, one of the characteristic features of
metabolic syndrome X, is a result of increased activity of 11B-hydroxysteroid
dehydrogenase-1 in the abdominal adipose tissue. Low-grade systemic
inflammation ...

Author: Shlomo Yehuda

Publisher: Springer Science & Business Media

ISBN: 9781592599523

Category: Medical

Page: 438

View: 448

A benchmark survey of current clinical findings on the complex interactions between diet, stress, and mental health, and their impact on disease states. The authors give special attention to the influence of stress on physical health, mental health, and cognitive function, including the critical effects of maternal nutritional status and stress levels on fetal physical and mental development, the role of lipids in the development and treatment of depression, the role of fish oil in the development of aggressive behaviors, and the consequences of obesity on stress and the development of eating disorders. Additional chapters examine the effects of stress on chronic disorders, women, and cardiac function, and the influence of inflammation on diet, neurological functions, disease incidence, and cognitive functions.
Categories: Medical

Nutritional Factors for Syndrome X

Nutritional Factors for Syndrome X

Obesity surgery is rapidly becoming a definitive and well proven way of
effectively treating obesity , but it comes with ... In fact , people with morbid
obesity are often extreme examples of the progression of Syndrome X to multiple
disabilities .

Author: Stephen Holt, M.D.

Publisher: Wellness Pub.

ISBN: 0971422486

Category: Insulin resistance

Page: 146

View: 504

Categories: Insulin resistance

Obesity Epidemiology

Obesity Epidemiology

Obesity triggers a plethora of metabolic disturbances, including insulin resistance
, hypertension, hyperglycemia, ... Defining the Metabolic Syndrome In his Banting
Award Lecture in 1988,2 Gerald Reaven used the term “Syndrome X” to ...

Author: Frank Hu

Publisher: Oxford University Press

ISBN: 0199718474

Category: Medical

Page: 512

View: 436

During the past twenty years there has been a dramatic increase in obesity in the United States. An estimated thirty percent of adults in the US are obese; in 1980, only fifteen percent were. The issue is gaining greater attention with the CDC and with the public health world in general. This book will offer practical information about the methodology of epidemiologic studies of obesity, suitable for graduate students and researchers in epidemiology, and public health practitioners with an interest in the issue. The book will be structured in four main sections, with the majority of chapters authored by Dr. Hu, and some authored by specialists in specific areas. The first section will consider issues surrounding the definition of obesity, measurement techniques, and the designs of epidemiologic studies. The second section will address the consequences of obesity, looking at epidemiologic studies that focus on cardio-vascular disease, diabetes, and cancer The third section will look at determinants obesity, reviewing a wide range of risk factors for obesity including diet, physical activity and sedentary behaviors, sleep disorders, psychosocial factors, physical environment, biochemical and genetic predictors, and intrauterine exposures. In the final section, the author will discuss the analytical issues and challenges for epidemiologic studies of obesity.
Categories: Medical

There Is a Cure for Diabetes

There Is a Cure for Diabetes

Metabolic Syndrome (Syndrome X) Syndrome X was first coined as a term by
Gerald Reaven, MD, at Stanford University ... Dr. Simeon Margolis, co-author of a
Johns Hopkins report on Syndrome X, says that abdominal obesity is often the
first ...

Author: Gabriel Cousens

Publisher: North Atlantic Books

ISBN: 1556436912

Category: Health & Fitness

Page: 446

View: 330

"Presents a breakthrough approach that reverses diabetes to a physiology of health and well-being by resetting the genetic expression of a person's DNA through green juice fasting and a 100% organic, nutrient-dense, vegan, low-glycemic, low-insulin-scoring, and high-mineral diet of living foods in the first 21 days"--Provided by publisher.
Categories: Health & Fitness

Metabolic Syndrome Pathophysiology

Metabolic Syndrome Pathophysiology

This epidemic of type 2 diabetes mellitus, along with that of obesity, is taking
place in both the developed and developing ... Reaven called it “Syndrome X,” It
is surprising that Reaven did not include obesity as one of the features of
metabolic ...

Author: Undurti N. Das

Publisher: John Wiley & Sons

ISBN: 9780813820712

Category: Medical

Page: 268

View: 957

Metabolic Syndrome Pathophysiology: The Role of Essential Fatty Acids provides current research exploring the links among insulin, insulin receptors, polyunsaturated fatty acids, brain growth and disease. Specific interactions of essential fatty acids and polyunsaturated fatty acids in brain development and several disease groups are described. The role of inflammation in disease and how fatty acids regulate low-systemic inflammation are examined and explained. Metabolic and neurologic dynamics are presented to provide a linkage between the presence of omega-3 and omega-6 and protection against diseases and conditions such as diabetes mellitus, obesity, autoimmune diseases and hypertension.
Categories: Medical

The Cortisol Connection

The Cortisol Connection

CORTISOL AND SYNDROMEX Most people have never even heard of syndrome
X ( also termed metabolic syndrome ) , which refers to a cluster of related
conditions and symptoms including diabetes , insulin resistance , obesity ...

Author: Shawn M. Talbott

Publisher: Hunter House

ISBN: 089793492X

Category: Health & Fitness

Page: 324

View: 567

Explores the documented relationship between levels of the stress hormone cortisol and a range of health disorders including obesity, depression, and hypertension, outlining how to control cortisol with supplements. Simultaneous.
Categories: Health & Fitness

Proceedings of the 9th International Congress on Obesity

Proceedings of the 9th International Congress on Obesity

CHAPTER 6 2 Role of genetic deficiency of fatty acid oxidation in metabolic
syndrome / obesity Philip A. Wood , David M. ... syndrome , also known as insulin
resistance syndrome or syndrome X , is a common clinical entity characterized by
a ...

Author: Geraldo Medeiros-Neto

Publisher: John Libbey Eurotext

ISBN: 2742004602

Category: Medical

Page: 1062

View: 802

Obesity is officially recognised as a major worldwide public health problem. "Progress in Obesity Research: 9" fulfils the need for an accessible and fundamental research, highly recommended towards a better understanding of obesity. It will prove an indispensable resource for all those involved in the research, prevention and treatment of obesity.
Categories: Medical

Overweight and the Metabolic Syndrome

Overweight and the Metabolic Syndrome

SUMMARY With the rising prevalence of obesity and insulin resistance syndrome
, the need for understanding how humans regulate body weight has grown ...
Why syndrome X? From Harold Himsworth to the insulin resistance syndrome.

Author: George A. Bray

Publisher: Springer Science & Business Media

ISBN: 9780387321646

Category: Medical

Page: 336

View: 581

This timely book provides an overview of topics related to obesity. These include associated health risks, childhood obesity, genetics, evaluation, treatment, behavioral strategies, and successes and failures in preventing obesity. The volume covers evaluation guidelines, different approaches to treatment, including diet, exercise, behavior, drugs, and surgery to deal with the current world-wide obesity epidemic.
Categories: Medical

A Perinatal Strategy For Preventing Adult Disease The Role Of Long Chain Polyunsaturated Fatty Acids

A Perinatal Strategy For Preventing Adult Disease  The Role Of Long Chain Polyunsaturated Fatty Acids

Chapter # 6 Metabolic Syndrome X and low - grade systemic inflammation The
most important features of Metabolic Syndrome X are : obesity , insulin resistance
/ hyperinsulinemia , dyslipidemia ( hypertriglyceridemia and low HDL ...

Author: Undurti N. Das

Publisher: Springer Science & Business Media

ISBN: 1402070705

Category: Medical

Page: 192

View: 270

This book proposes that fetal growth retardation and low-gradesystemic inflammation can be prevented by perinatal supplementation oflong-chain polyunsaturated fatty acids (LCPUFAs). Evidence for thishypothesis is presented and discussed in detail, along with possiblemechanisms by which these substances produce beneficial actions.Finally, it is suggested that provision of adequate amounts of LCPUFAsduring the perinatal period prevents insulin resistance, obesity, type2 diabetes mellitus, hypertension, CHD, and Alzheimer's disease in theadult. Means of testing the hypothesis are also presented. Thus, thebook suggests a simple and novel method of preventing diseases thatare increasing in incidence in both the developed and developingworlds.
Categories: Medical