New Natural Products and Plant Drugs with Pharmacological Biological or Therapeutical Activity

New Natural Products and Plant Drugs with Pharmacological  Biological or Therapeutical Activity

The fact that, of the approximately 600,000 plant species existing on the earth, only some 5 % have been specifically investigated chemically or pharmacologi cally, is a challenge to chemists spezializing in na tural substances and to ...

Author: H.K. Wagner

Publisher: Springer Science & Business Media

ISBN: 9783642666827

Category: Medical

Page: 288

View: 370

The fact that, of the approximately 600,000 plant species existing on the earth, only some 5 % have been specifically investigated chemically or pharmacologi cally, is a challenge to chemists spezializing in na tural substances and to pharmacologists. In view of the limited number of research capacities and the ever diminishing financial means, this challenge can only be met if, together with an improvement and refinement of methods of analysis, medicinal plant research is carried out on a broader interdisciplinary basis, with comparable, scientifically recognized screening methods, and if it is better coordinated, with greater use of modern documentation means. It is thus necessary in the future to concentrate specifically on projects leading to the development of new medicinal prepara tions. The plenary lectures hold in the present symposium of the 1st International Congress for Research on Medi cinal Plants reflect these efforts and tendencies. At the same time they provide a survey of some of the fields of medicinal plant research which are at present most actual and most intensively researched. They range from plant screening, isolation and structure eluci dation of new principles, to the therapeutical opti mization of a natural product. The lectures given at this congress show clearly the necessity, in addition to national phytochemical so cieties, for a central international organisation, in which all active medicinal plant researchers in the world are included. Their aim should be to provide the impulse for more optimal, rational research, aimed at the solution of specific projects.
Categories: Medical

Natural Products of Woody Plants

Natural Products of Woody Plants

Some of the extraneous components of wood are too insoluble to be ex tracted by inert solvents and remain to give extractive-free wood its color; very often these are high-molecular-weight polyphenolics.

Author: John W. Rowe

Publisher: Springer Science & Business Media

ISBN: 9783642740756

Category: Science

Page: 1243

View: 777

Wood as found in trees and bushes was of primary importance to ancient humans in their struggle to control their environment. Subsequent evolution through the Bronze and Iron Ages up to our present technologically advanced society has hardly diminished the importance of wood. Today, its role as a source of paper products, furniture, building materials, and fuel is still of major significance. Wood consists of a mixture of polymers, often referred to as lignocellulose. The cellulose micro fibrils consist of an immensely strong, linear polymer of glucose. They are associated with smaller, more complex polymers composed of various sugars called hemicelluloses. These polysaccharides are embedded in an amorphous phenylpropane polymer, lignin, creating a remarkably strong com posite structure, the lignocellulosic cell wall. Wood also contains materials that are largely extraneous to this lignocellulosic cell wall. These extracellular substances can range from less than 1070 to about 35% of the dry weight of the wood, but the usual range is 2% -10%. Among these components are the mineral constituents, salts of calcium, potassium, sodium, and other metals, particularly those present in the soil where the tree is growing. Some of the extraneous components of wood are too insoluble to be ex tracted by inert solvents and remain to give extractive-free wood its color; very often these are high-molecular-weight polyphenolics.
Categories: Science

Natural Products from Plants Second Edition

Natural Products from Plants  Second Edition

2008 NOMINEE The Council on Botanical and Horticultural Libraries Annual Award for a Significant Work in Botanical or Horticultural Literature From medicinal, industrial, and culinary uses to cutting-edge laboratory techniques in modern ...

Author: Leland J. Cseke

Publisher: CRC Press

ISBN: 9781420004472

Category: Science

Page: 632

View: 120

2008 NOMINEE The Council on Botanical and Horticultural Libraries Annual Award for a Significant Work in Botanical or Horticultural Literature From medicinal, industrial, and culinary uses to cutting-edge laboratory techniques in modern research and plant conservation strategies, Natural Products from Plants, Second Edition reveals a vastly expanded understanding of the natural products that plants produce. In a single volume, this bookoffers a thorough inventory of the various types of plant-derived compounds. It covers their chemical composition, structure, and properties alongside the most effective ways to identify, extract, analyze, and characterize new plant-derived compounds. The authors examine new information on the chemical mechanisms plants use to deter predators and pathogens, attract symbiotic organisms, and defend themselves against environmental stress—insights which are key for adapting such mechanisms to human health. Along with updated and revised information from the highly acclaimed first edition, the second edition presents seven new chapters and features more than 50% new material relating to plant constituents, natural product biochemistry, and molecular biology. The book incorporates in-depth treatment of natural product biosynthesis with new collection and extraction protocols, advanced separation and analytical techniques, up-to-date bioassays, as well as modern molecular biology and plant biotechnology for the production of natural products. Unique in its breadth and coverage, Natural Products from Plants, Second Edition belongs on the shelf of interested researchers, policymakers, and consumers— particularly those involved in disease prevention, treatment, and pharmaceutical applications—who need a complete guide to the properties, uses, and study of plant natural products.
Categories: Science

Natural Products from Plants

Natural Products from Plants

This new volume fills this need, bringing together relevant, practical information about the various types of natural products produced by plants, why they produce them, and their importance in today's world.

Author: Leland J. Cseke

Publisher: CRC Press

ISBN: 1420049356

Category: Science

Page: 368

View: 816

There has long been a need for an authoritative source on natural products and plants and how they are used. This new volume fills this need, bringing together relevant, practical information about the various types of natural products produced by plants, why they produce them, and their importance in today's world. Natural Products from Plants provides examples of how plant products are used to benefit humans through prevention and treatment of diseases, nutritional value, pest control, dyes, fibers, foods and beverages, flavorings and fragrances, and in creating many other novel compounds. Scientists from various disciplines-chemists, biologists, physicians, ethnobotanists, ecologists, nutritionists, and others-are interested in using natural products from plants, but must be aware of the potentially harmful effects of such compounds. Some plants are sources of poisons, addictive drugs, and hallucinogens. Anyone looking for a thorough understanding of the properties of natural plant products - both beneficial and harmful - will find the answers in Natural Products from Plants.
Categories: Science

Chemistry of Plant Natural Products

Chemistry of Plant Natural Products

Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products.

Author: Sunil Kumar Talapatra

Publisher: Springer

ISBN: 3662519410

Category: Science

Page: 1180

View: 892

Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products. Beginning with a general introduction to set the context, the authors then go on to carefully detail nomenclature, occurrence, isolation, detection, structure elucidation (by both degradation and spectroscopic techniques) stereochemistry, conformation, synthesis, biosynthesis, biological activity and commercial applications of the most important natural products of plant origin. Each chapter also includes detailed references (with titles) and a list of recommended books for additional study making this outstanding treatise a useful resource for teachers of chemistry and researchers working in universities, research institutes and industry.
Categories: Science

Plant Natural Products

Plant Natural Products

In contrast to existing books which either focus exclusively on the pharmacological properties of plant natural products or cover the secondary metabolism of plants as one section in general plant science book, this is the first to cover ...

Author: Herwig O. Gutzeit

Publisher: John Wiley & Sons

ISBN: 9783527682003

Category: Science

Page: 434

View: 770

In contrast to existing books which either focus exclusively on the pharmacological properties of plant natural products or cover the secondary metabolism of plants as one section in general plant science book, this is the first to cover all aspects in one volume. It has all the features of a modern textbook, including color figures, questions and answers and a complimentary website. In addition, the introductory chapters provide sufficient background knowledge in the chemistry and biochemistry of plant natural products and their biotechnological applications to allow its use as a true stand-alone text for student courses.
Categories: Science

Plant Natural Products for Human Health

Plant Natural Products for Human Health

Plants have served mankind as an important source of foods and medicines.

Author: Chun-Tao Che

Publisher: MDPI

ISBN: 9783038977124

Category: Social Science

Page: 514

View: 724

Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own “traditional medicine” or as “complementary and alternative medicine”. From a pharmaceutical point of view, many compounds obtained from plant sources have long been known to possess bio/pharmacological activities, and historically, plants have yielded many important drugs for human use, from morphine discovered in the early nineteenth century to the more recent paclitaxel and artemisinin. Today, we are witnessing a global resurgence in interest and use of plant-based therapies and botanical products, and natural products remain an important and viable source of lead compounds in many drug discovery programs. This Special Issue on “Plant Natural Products for Human Health” compiles a series of scientific reports to demonstrate the medicinal potentials of plant natural products. It covers a range of disease targets, such as diabetes, inflammation, cancer, neurological disease, cardiovascular disease, liver damage, bacterial, and fungus infection and malarial. These papers provide important insights into the current state of research on drug discovery and new techniques. It is hoped that this Special Issue will serve as a timely reference for researchers and scholars who are interested in the discovery of potentially useful molecules from plant sources for health-related applications.
Categories: Social Science

Natural Products from Plants

Natural Products from Plants

This new volume fills this need, bringing together relevant, practical information about the various types of natural products produced by plants, why they produce them, and their importance in todays world.

Author: Leland J. Cseke

Publisher: CRC Press

ISBN: 084933134X

Category: Science

Page: 368

View: 531

There has long been a need for an authoritative source on natural products and plants and how they are used. This new volume fills this need, bringing together relevant, practical information about the various types of natural products produced by plants, why they produce them, and their importance in today's world. Natural Products from Plants provides examples of how plant products are used to benefit humans through prevention and treatment of diseases, nutritional value, pest control, dyes, fibers, foods and beverages, flavorings and fragrances, and in creating many other novel compounds. Scientists from various disciplines-chemists, biologists, physicians, ethnobotanists, ecologists, nutritionists, and others-are interested in using natural products from plants, but must be aware of the potentially harmful effects of such compounds. Some plants are sources of poisons, addictive drugs, and hallucinogens. Anyone looking for a thorough understanding of the properties of natural plant products - both beneficial and harmful - will find the answers in Natural Products from Plants.
Categories: Science

Natural Products of Silk Road Plants

Natural Products of Silk Road Plants

This volume, part of a world-wide series, has been prepared for university students of chemistry and ethno-botany and for those wishing to broaden knowledge.

Author: Raymond Cooper

Publisher: CRC Press

ISBN: 0367184338

Category: Botanical chemistry

Page: 292

View: 477

This volume, part of a world-wide series, has been prepared for university students of chemistry and ethno-botany and for those wishing to broaden knowledge. Plants, many indigenous to countries along the trading routes of the Silk Road, yielded medicines, cereals, spices, beverages, dyes and euphoric and exotic compounds. The book opens a window on a vast region of Asia not well described for its flora providing new and fresh insights upon: significant plants, some endangered traditional and modern applications of extracts the biochemical and pharmacological properties of extracts The Silk Road, a complex network of trade routes linking China with the rest of the Eurasian continent by land and sea, fostered transformation of the ethnic, cultural and religious identities of diverse peoples. The significance of the Silk Road is being revived today through immense investment by China and other eastern countries in major schemes of transport infrastructure.
Categories: Botanical chemistry

Natural Products

Natural Products

A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies.

Author: Lixin Zhang

Publisher: Springer Science & Business Media

ISBN: 9781592599769

Category: Medical

Page: 386

View: 431

A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Categories: Medical

Plant Based Natural Products

Plant Based Natural Products

Audience This book is a useful reference for academics, engineers and post-graduate students working in the fields of dyes and pigments, medicinal chemistry, bioremediation and environmental sciences, textiles, and materials science.

Author: Shahid Ul-Islam

Publisher: John Wiley & Sons

ISBN: 9781119423874

Category: Science

Page: 240

View: 516

Intense research has been started all around the world in the past few decades to exploit different agents from natural products as eco-friendly alternative to synthetic and toxic chemicals. Natural products and their derivatives have received increasing attention for their use in many everyday applications ranging from food, medicine, textiles, and healthcare.This new book presents significant research advances about the use of natural products, mainly plant colorants, bioactive compounds and other plant extracts in the textile coloration, food, bioremediation and environmental applications. There are total eight chapters contributed by leading researchers covering the topics such as potential resurgence of natural dyes in applied fields, natural colorants from indigoid plants, phytochemistry of dye yielding plants, irradiation as novel pretreatment methods, dyeing studies with henna plant, phytoremediation of arsenic, and synthesis of curcumin complexes for medicinal and other industrial uses.
Categories: Science

Handbook on Drugs from Natural Sources

Handbook on Drugs from Natural Sources

This book contains development of new drugs from plants, work on some Thai medicinal plants, plant growth based on Jasmonates, marine sterols, bleomycin and its derivatives, drugs from cannabinoids, bioactive compounds from nature, fungi ...

Author: H. Panda

Publisher: ASIA PACIFIC BUSINESS PRESS Inc.

ISBN: 9788178331331

Category:

Page: 480

View: 700

Natural products have played an important role throughout the world in treating and preventing human diseases. Natural product medicines have come from various materials including terrestrial plants, terrestrial microorganisms, organisms etc. Historical experiences with plants as therapeutic tools have helped to introduce single chemical entries in modern medicine. About 40% of the drugs used are derived from natural sources. Most are pure substances which are isolated from various organisms & used directly or after chemical modification. Natural products will continue to be important in three areas of drug discovery: as targets for production by biotechnology as a source of new lead compounds of novel chemical structure and as the active ingredients of useful treatments derived from traditional systems. Biotechnology will contribute more new natural products for medicinal use. Plants provide a fertile source of natural products many of which are clinically important medicinal agents. Natural products have traditionally provided most of the drugs in use. Despite the achievements of synthetic chemistry and the advances towards rational drug design, natural products continue to be essential in providing medicinal compounds and as starting points for the development of synthetic analogues. With the increasing power of screening programs and the increasing interest in the reservoir of untested natural products, many future drug developments will be based, at least in part, on natural products. The major contents of the book are plant products produced in cell culture , application of genetic engineering to the production of pharmaceuticals , anti transpirants and plant growth regulators based , the potential and the problems of marine natural products, marine sterols, plants as a source of anti-inflammatory substances, anti hepatotoxic principles in oriental medicinal plants, immune stimulants of fungi and higher plants, amanita muscaria in medicinal chemistry, ergot alkaloids and their derivatives in medicinal chemistry and therapy, development of drugs from cannabinoids, etc. This book contains development of new drugs from plants, work on some Thai medicinal plants, plant growth based on Jasmonates, marine sterols, bleomycin and its derivatives, drugs from cannabinoids, bioactive compounds from nature, fungi and higher plants, biological active compounds from British Marine, microbial phytotoxins as herbicides and many more. This book will be very helpful to its readers, upcoming entrepreneurs, scientists, existing industries, technical institutions, druggist etc.
Categories:

Medicinal Natural Products

Medicinal Natural Products

This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals.

Author: Paul M. Dewick

Publisher: John Wiley & Sons

ISBN: 0471496413

Category: Medical

Page: 507

View: 831

This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.
Categories: Medical

Agrochemicals from Natural Products

Agrochemicals from Natural Products

Offers a thorough overview of the important agricultural applications of both natural products and synthetic compounds derived from natural products, presenting detailed information on the isolation, structural studies, biological activity ...

Author: C.R.A. Godfrey

Publisher: CRC Press

ISBN: 0824795539

Category: Science

Page: 424

View: 298

Offers a thorough overview of the important agricultural applications of both natural products and synthetic compounds derived from natural products, presenting detailed information on the isolation, structural studies, biological activity and toxicology of these compounds. The expanding area of insecticidal natural products is highlighted.
Categories: Science

Lead Molecules from Natural Products

Lead Molecules from Natural Products

This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design.

Author:

Publisher: Elsevier

ISBN: 0080459331

Category: Science

Page: 448

View: 112

Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations. * Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents.
Categories: Science

Pharmacological Assays of Plant Based Natural Products

Pharmacological Assays of Plant Based Natural Products

This volume provides information on how to select and screen plants for their medicinal properties.

Author: Thangaraj Parimelazhagan

Publisher: Springer

ISBN: 9783319268118

Category: Medical

Page: 188

View: 469

This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant’s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.
Categories: Medical

Introduction to Natural Products Chemistry

Introduction to Natural Products Chemistry

This book represents the continuing collaboration between the fields of natural products chemistry, medicine, biology, and agriculture which will continue to discover and implement novel chemical products from natural sources.

Author: Rensheng Xu

Publisher: CRC Press

ISBN: 9781439860762

Category: Medical

Page: 381

View: 864

Natural products chemistry—the chemistry of metabolite products of plants, animals and microorganisms—is involved in the investigation of biological phenomena ranging from drug mechanisms to gametophytes and receptors and drug metabolism in the human body to protein and enzyme chemistry. Introduction to Natural Products Chemistry has collected the most important research results of natural product chemistry in China. It overviews the basic principles of isolation, structure, and characteristics of natural products and illustrates current research techniques of structure elucidation with real-life examples of wet chemistry and spectroscopic analyses (UV, IR, MS, and NMR, especially 2d-NMR, HMBC, and HMQC), bioactivity, biosynthesis, and chemical synthesis. Specifically, this book covers: Extraction and isolation of natural products Chemistry of fungal products Alkaloids, sesquiterpenoids, diterpenes, and saponins Amino acids and peptides Flavonoids, anthraquinones, coumarins, and lignans Marine natural products Structural modification of active principles from traditional Chinese medicine Chemical synthesis of natural products Although natural products chemistry has produced enormous results and made great contributions to human health, industry, and agriculture, only a fraction of natural resources have been rigorously studied. Chinese natural products are a gold mine for further exploration with modern technology and methods. This book represents the continuing collaboration between the fields of natural products chemistry, medicine, biology, and agriculture which will continue to discover and implement novel chemical products from natural sources.
Categories: Medical

Proceedings of 4th International Conference and Exhibition on Natural Products Medicinal Plants Marine Drugs 2018

Proceedings of 4th International Conference and Exhibition on Natural Products  Medicinal Plants   Marine Drugs 2018

June 11-12, 2018 Rome, Italy Key Topics : Natural Products, Development of Marine Drugs and Natural Products, Natural Products Chemistry, Natural Products Drug Discovery, Phytomedicine and Phytochemistry, Medicinal Natural Products, Natural ...

Author: ConferenceSeries

Publisher: ConferenceSeries

ISBN:

Category:

Page: 98

View: 249

June 11-12, 2018 Rome, Italy Key Topics : Natural Products, Development of Marine Drugs and Natural Products, Natural Products Chemistry, Natural Products Drug Discovery, Phytomedicine and Phytochemistry, Medicinal Natural Products, Natural Products as Anti-Cancer Drugs, Marine: The Ultimate Source of Bioactives and Drug Metabolites, Marine Biotechnology, New Sources and Approaches to Natural Products, Marine Natural Products Drug Discovery, Bioactive Natural Products, Bioactive Natural Products from Marine Bacteria, Marine Probiotics and Prebiotics, A Promising Future for Marine Drugs and Natural Products, Medicinal Chemistry & Drug Discovery, Anti-cancer agents in Medicinal Plants, Therapeutic Drugs and Personalized Medicines,
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Natural Products

Natural Products

A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies.

Author: Lixin Zhang

Publisher: Springer

ISBN: 1588293831

Category: Medical

Page: 382

View: 665

An examination of the past successes of natural products as medicines and their future from both conventional and new technologies. This work shows how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be productive and efficacious.
Categories: Medical

Natural Products Chemistry of Botanical Medicines from Cameroonian Plants

Natural Products Chemistry of Botanical Medicines from Cameroonian Plants

This book highlights how many of the extracts from Cameroon are today associated with important drugs, nutrition products, beverages, perfumes, cosmetics and pigments, as well as presenting their complex chemistry and structure.

Author: Taylor & Francis Group

Publisher: CRC Press

ISBN: 1138581429

Category:

Page: 192

View: 339

A contribution to the series on Natural Products Chemistry of Global Plants, Natural Products Chemistry of Botanical Medicines from Cameroon focuses on the sources and chemistry of natural products from plants in Cameroon, West Africa. The plants selected offer an opportunity to trace a route through history from ancient civilizations to the modern day, showing the important value to man of natural products in medicines and in foods. This book highlights how many of the extracts from Cameroon are today associated with important drugs, nutrition products, beverages, perfumes, cosmetics and pigments, as well as presenting their complex chemistry and structure. Key Features: Forms an important part of the series on Natural Products Chemistry of Global Plants, as Cameroon is a country with rich experience in the use of medicinal plants and with a wide diversity of botanical resources Addresses the current development of pharmacognosy research in Cameroon Provides readers with updated information on the chemistry and pharmacology of natural products with pharmaceutical potential Covers an extensive range of chemical, botanical and pharmacological diversities Xavier Siwe Noundou is a Scholar/Scientist based at Rhodes University in Grahamstown, South Africa. He has been a EU FP7 Marie Curie Fellow (2015-2016), Kaposvar University in Hungary (2015, 2016), Trakia Univesity in Bulgaria (2016), TWAS Fellow (2013), National Research Foundation South Africa Fellow (2014-2016). Dr Noundou works on Medicinal Chemistry focusing on Chemistry, Pharmacognosy and Nanotechnology. His main research interests include terrestrial natural products chemistry (from Cameroon and South Africa) and marine natural products chemistry (from the South African coastline): bioactive metabolites isolated as potential antiparasitic, antimicrobial, antiviral and antiproliferative candidates. He is author of more than forty scientific publications in his field of expertise.
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