Measuring Biological Impacts of Nanomaterials

Measuring Biological Impacts of Nanomaterials

Measuring. the. Biological. Impact. of. Nanomaterials. by. Impedance. Analysis: A.
Multimodal. Approach. Analyzing the biological impact of nanomaterials by label-
free approaches is still in its infancy. Researchers all over the globe have just ...

Author: Joachim Wegener

Publisher: Springer

ISBN: 9783319248233

Category: Science

Page: 214

View: 470

This book reviews several aspects of the biological response to nanoscale particles on a molecular and cellular level. Nanoscale materials and nanoscale particles in particular have interesting properties and beneficial applications. While they thus have entered our daily lifes on many different levels (from electronics, over textiles, packaging or surface modifications, to biomedical applications), general rules describing their interaction with biological structures and biological matter are still difficult to derive. The existing literature suggests a variety of interaction schemes between nanoparticles and biological objects, not dispelling the public concerns about possible health effects and harmful properties. A systematic approach to the problem is needed and timely. This book specifically emphasizes bioanalytical problems starting from the characterization of the nanomaterials to the pitfalls and potential artifacts of state-of-the-art cytotoxicity assays that are frequently used to study harmful effects on cells. It also highlights the application of label-free bioanalytical techniques that can potentially complement the present approaches and hence provide new perspectives on this highly discussed cutting-edge field of research and public concern.
Categories: Science

Environmental Nanotechnology

Environmental Nanotechnology

Written by a team of 29 leading experts from around the world, this comprehensive book presents cutting-edge coverage of the fabrication, characterization, and measurement of nanomaterials...emerging markets for nanomaterials.. ...

Author: Mark Wiesner

Publisher: McGraw Hill Professional

ISBN: 0071511040

Category: Technology & Engineering

Page: 540

View: 379

Explore the Properties of Today's Widely Used Nanomaterials— and Assess Their Potentially Harmful Effects on the Environment Environmental Nanotechnology is the first book to assist you in both understanding the properties of new nanomaterial-centered technology and assessing the potentially harmful effects these materials may have on the environment. Written by a team of 29 leading experts from around the world, this comprehensive book presents cutting-edge coverage of the fabrication, characterization, and measurement of nanomaterials...emerging markets for nanomaterials...nanotechnologies in the energy industry...nanotechnologies for environmental quality...nanotechnology transport and fate in the environment...toxicological impacts of nanomaterials...and much more. Filled with detailed illustrations, Environmental Nanotechnology features: State-of-the-art techniques for the characterization and measurement of nanomaterials The latest findings on the transport and fate of nanomaterials in the environment Nanotechnologies for energy production, storage, and distribution In-depth analyses of the ecotoxicological impacts of nanomaterials New methods for developing nanomaterials with less environmental risk Inside This Landmark Environmental Engineering Guide _ • Nanomaterials: New Challenges and Opportunities • Fabrication of Nanomaterials • Characterization and Measurement of Nanomaterials • Emerging Markets for Nanomaterials • Nanomaterial-Enabled Technologies for Energy Production, Storage, and Distribution • Nanomaterial-Enabled Technologies for Environmental Quality • Nanomaterial Transport and Fate in the Environment • Ecotoxicological Impacts of Nanomaterials • Toxicological Impacts of Nanomaterials
Categories: Technology & Engineering

Safety Aspects of Engineered Nanomaterials

Safety Aspects of Engineered Nanomaterials

With contributions from leading researchers and government experts involved with the safety assessment of nanomaterials, this book gives an up-to-date review on the safety of engineered nanomaterials and their impact on health and the ...

Author: Wolfgang Luther

Publisher: CRC Press

ISBN: 9789814364867

Category: Science

Page: 398

View: 758

With contributions from leading researchers and government experts involved with the safety assessment of nanomaterials, this book gives an up-to-date review on the safety of engineered nanomaterials and their impact on health and the environment. It covers the whole nanomaterial life cycle—from production, transport, and distribution in the environment to biological responses and toxicology. The book also addresses occupational safety measures as well as societal and economic contexts, such as medical applications of nanomaterials, public acceptance, and risk communication and management.
Categories: Science

The Two Faces of Nanomaterials

The Two Faces of Nanomaterials

Nanoparticles are taken up and transported within subcellular structures that are
surrounded by one or two layers of ... In Measuring Biological Impacts of
Nanomaterials; Maximilien, J., Beyazit, S., Rossi, C., Haupt, K., Bui, B.T.S., Eds.; ...

Author: Dong-Wook Han

Publisher: MDPI

ISBN: 9783039289837

Category: Medical

Page: 146

View: 654

Due to properties differing from those of larger materials, nanomaterials have been extensively used in different areas including nanomedicine, drug delivery, theragnosis, and bioimaging in recent years. Evaluating the toxicity profile (i.e., biocompatibility) of nanomaterials and their impact on health is essential to support the potential biomedical applications. This book deals with the two faces of nanomaterials, toxicity and bioactivity, hoping to aid with their development for clinical applications, reducing the possible risks associated with their use.
Categories: Medical

Adverse Effects of Engineered Nanomaterials

Adverse Effects of Engineered Nanomaterials

In particular, “omics” technologies could provide tools to measure biological
responses to exposures, as reflected by profiles or signatures of transcripts,
proteins, or metabolites. Despite the multitude of possible key markers, small
biological ...

Author: Bengt Fadeel

Publisher: Academic Press

ISBN: 9780128094907

Category: Medical

Page: 486

View: 146

Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety. Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population. Uses a schematic, non-exhaustive approach to summarizes the most important research data in this field Discusses the health implications of experimental data in nanotoxicology Presents a completely revised edition that focuses on the human health impacts of engineered nanomaterials, including many organ-specific chapters
Categories: Medical

Research on Environmental and Safety Impacts of Nanotechnology

Research on Environmental and Safety Impacts of Nanotechnology

However , for nanomaterials this traditional technique may not be a useful metric
for assessing biological effects . ... That applies both to measurement of body
burden for in vivo studies and to cellular uptake studies in vitro . Few tools exist to
 ...

Author: United States. Congress. House. Committee on Science

Publisher:

ISBN: PSU:000058937709

Category: Federal government

Page: 191

View: 102

Categories: Federal government

Nanomaterial Characterization

Nanomaterial Characterization

With some nanomaterial samples, getting reliable data is not easy to achieve and
can lead to a situation in which ... the physicochemical properties measured at a
given time may not be directly associated with observed biological effects.

Author: Ratna Tantra

Publisher: John Wiley & Sons

ISBN: 9781118753590

Category: Science

Page: 320

View: 704

Introduces basic knowledge for nanomaterial characterization focusing on key properties and the different analytical techniques available Provides a quick reference to different analytical methods for a given property highlighting their pros and cons Presents numerous case studies, ranging from characterizing nanomaterials in coffee creamer suspension to measurement of airborne dust exposure levels Provides an introduction to other topics that are strongly related to nanomaterial characterization e.g. synthesis, reference material and metrology Includes state of the art techniques: scanning tunneling microscopy under extreme conditions, novel strategy for biological characterization and methods to visualize multidimensional characterization data
Categories: Science

Metrology and Standardization for Nanotechnology

Metrology and Standardization for Nanotechnology

This book gives an overview of the current status of nanotechnology including the importance of metrology and characterization at the nanoscale, international standardization of nanotechnology, and industrial innovation of nano-enabled ...

Author: Elisabeth Mansfield

Publisher: John Wiley & Sons

ISBN: 9783527340392

Category: Science

Page: 626

View: 376

For the promotion of global trading and the reduction of potential risks, the role of international standardization of nanotechnologies has become more and more important. This book gives an overview of the current status of nanotechnology including the importance of metrology and characterization at the nanoscale, international standardization of nanotechnology, and industrial innovation of nano-enabled products. First the field of nanometrology, nanomaterial standardization and nanomaterial innovation is introduced. Second, major concepts in analytical measurements are given in order to provide a basis for the reliable and reproducible characterization of nanomaterials. The role of standards organizations are presented and finally, an overview of risk management and the commercial impact of metrology and standardization for industrial innovations.
Categories: Science

Smart Materials and Nanotechnology in Engineering

Smart Materials and Nanotechnology in Engineering

However,the long-term chronic effects of nanomaterials on living systems is
neglected. ... Introduction: The blossom of manufactured nano-materials leads to
substantive changes in biology field. ... It evokes our deep thought that what is the
mechanism of the carbon-based nano-material and how to measure its harm for ...

Author: J.L. Zhong

Publisher: Trans Tech Publications Ltd

ISBN: 9783038137443

Category: Technology & Engineering

Page: 460

View: 476

Volume is indexed by Thomson Reuters CPCI-S (WoS). This volume comprises a collection of the papers presented at the 2011 International Conference on Smart Materials and Nanotechnology in Engineering (SMNE2011), held on September 17~18th, 2011, in Wuhan, China. The aim was to provide a platform where researchers, engineers, academics and industrialists from all over the world could present research results and developments in Smart Materials and Nanotechnology in Engineering. This makes the work an eminently up-to-date guide to those fields.
Categories: Technology & Engineering

Nanomaterials

Nanomaterials

The idea for this book was conceived at the NATO Advanced Research Workshop (ARW) on “Nanomaterials: Environmental Risks and Benefits and Emerging Consumer Products. ” This meeting – held in Algarve, Portugal, in April 2008 – ...

Author: Charles Lutz

Publisher: Springer Science & Business Media

ISBN: 9781402094910

Category: Technology & Engineering

Page: 472

View: 395

Many potential questions regarding the risks associated with the development and use of wide-ranging technologies enabled through engineered nanomaterials. For example, with over 600 consumer products available globally, what information exists that describes their risk to human health and the environment? What en- neering or use controls can be deployed to minimize the potential environmental health and safety impacts of nanomaterials throughout the manufacturing and product lifecycles? How can the potential environmental and health benefits of nanotechnology be realized and maximized? The idea for this book was conceived at the NATO Advanced Research Workshop (ARW) on “Nanomaterials: Environmental Risks and Benefits and Emerging Consumer Products. ” This meeting – held in Algarve, Portugal, in April 2008 – started with building a foundation to harmonize risks and benefits associated with nanomaterials to develop risk management approaches and policies. More than 70 experts, from 19 countries, in the fields of risk assessment, decision-analysis, and security discussed the current state-of-knowledge with regard to nanomaterial risk and benefits. The discussion focused on the adequacy of available risk assessment tools to guide nanomaterial applications in industry and risk governance. The workshop had five primary purposes: Describe the potential benefits of nanotechnology enabled commercial products. Identify and describe what is known about environmental and human health risks of nanomaterials and approaches to assess their safety. Assess the suitability of multicriteria decision analysis for reconciling the benefits and risks of nanotechnology.
Categories: Technology & Engineering

Nanotechnology and Human Health

Nanotechnology and Human Health

For most classes of nanoparticles, there is still insufficient understanding of
dissolution and agglomeration dynamics in biological ... The characterization of
nanoparticles for nanotoxicology, due to the described observations, requires
careful adaptation of measurement conditions. ... can provide the basis for a
reliable understanding of relations between material properties and biological
effects. However ...

Author: Ineke Malsch

Publisher: CRC Press

ISBN: 9780849381447

Category: Technology & Engineering

Page: 376

View: 178

Addressing medium- and long-term expectations for human health, this book reviews current scientific and technical developments in nanotechnology for biomedical, agrofood, and environmental applications. This collection of perspectives on the ethical, legal, and societal implications of bionanotechnology provides unique insight into contemporary technological developments. Readers with a technical background will benefit from the overview of the state-of-the-art research in their field, while readers with a social science background will benefit from the discussion of realistic prospects of nanotechnology. The text also includes a glossary as well as extensive end-of-chapter references.
Categories: Technology & Engineering

Environmental Nanotechnology Applications and Impacts of Nanomaterials Second Edition

Environmental Nanotechnology  Applications and Impacts of Nanomaterials  Second Edition

The arrows indicate how considerations for nanoecotoxicology scale across
these levels of biological organization ... This is because it is often assumed that
measurement of parameters such as growth, metabolism, reproduction, and
mortality ...

Author: Mark Wiesner

Publisher: McGraw Hill Professional

ISBN: 9780071828451

Category: Technology & Engineering

Page: 320

View: 346

Extensively revised and featuring new material, this timely, advanced resource covers the impacts of nanomaterials on organisms and ecosystems and their applications within industry. Cowritten by leaders of two of the most prominent research groups in the world considering the effects of nanomaterials on the environment, the second edition of Environmental Nanotechnology addresses the cutting-edge advances in this area. There is now much more known about the impacts of nanomaterials on organisms and ecosystems. Methods have been developed where there were few accepted procedures in the past. Thinking has evolved to consider the life cycle effects of nanomaterial production, and tools for risk forecasting are now under development. There has also been some experience among academics in using this book as the basis for new courses on Environmental Nanotechnology. Three new chapters cover the life cycle of nanomaterial fabrication and use and estimating nanomaterial exposure in the environment. A systematic discussion of the effects of nanomaterials on organisms and ecosystems is included, where the previous edition was largely limited to speculation. Features 75% new material New chapter on the life cycle aspects of nanomaterial fabrication and use Two new chapters on estimating nanomaterial exposure in the environment: implications that explore nanotoxicology; exposure estimation Contains end-of-chapter problems and questions
Categories: Technology & Engineering

Nanoscience and Nanotechnology

Nanoscience and Nanotechnology

Environmental and Health Impacts Vicki H. Grassian ... charge Surface Reactivity
Quantitative adsorption studies Dissolution measurements to the specific
properties of the nanomaterials. ... of both inhalation and instillation exposure
methods, are recommended with the largest biological investigations on
pulmonary effects.

Author: Vicki H. Grassian

Publisher: John Wiley & Sons

ISBN: 9780470396605

Category: Science

Page: 512

View: 401

This comprehensive book covers various aspects of nanoscience and nanotechnology and what is known about the potential environmental and health impacts. Divided into three main sections, the book addresses the toxicity of nanomaterials, fate and transport of nanomaterials in the environment, and occupational health aspects of nanotechonology.
Categories: Science

The Global Technology Revolution 2020 In Depth Analyses Bio Nano Materials Information Trends Drivers Barriers and Social Implications

The Global Technology Revolution 2020  In Depth Analyses  Bio Nano Materials Information Trends  Drivers  Barriers  and Social Implications

As a result, the availability of biological information—the gene sequence of an
individual, the molecular markers for a ... techniques through which levels of
pollutants within individuals can be measured even though the health effects of
the ...

Author: Richard Silberglitt

Publisher: Rand Corporation

ISBN: 0833041142

Category: Technology & Engineering

Page: 314

View: 897

In 2020, areas of particular importance for technology trends will include biotechnology, nanotechnology, materials technology, and information technology. This report, the companion document to The Global Technology Revolution 2020, Executive Summary (Silberglitt et al., MG-475-NIC, 2006), assesses in detail a sample of 29 countries with respect to their ability to acquire and implement 16 key technology applications.
Categories: Technology & Engineering

Implications of Nanotechnology for Environmental Health Research

Implications of Nanotechnology for Environmental Health Research

Today, science is at the optimal time to begin to study the impact of
nanomaterials on human health, said Vicki Colvin of Rice University. ... Two of its
primary objectives are to maintain a comprehensive database and develop
quantitative ways of measuring nanomaterials. ... there is a wealth of knowledge
on incidental nanoparticles and how these particles interact with biological
organisms, noted Colvin.

Author: Institute of Medicine

Publisher: National Academies Press

ISBN: 9780309095778

Category: Technology & Engineering

Page: 70

View: 303

Nanotechnology is often described as an emerging technology - one that not only holds promise for society, but also is capable of revolutionizing our approaches to common problems. Nanotechnology is not a completely new field; however, it is only recently that discoveries in this field have advanced so far as to warrant examination of their impact upon the world around us. Nanotechnology has direct beneficial applications for medicine and the environment, but like all technologies it may have unintended effects that can adversely impact the environment, both within the human body and within the natural ecosystem. How does the science move forward in a way that best protects the public and gets health and safety right the first time? Implications of Nanotechnology for Environmental Health Research identifies the areas in which additional research is needed and the processes by which changes can occur.
Categories: Technology & Engineering

Aerosols Handbook

Aerosols Handbook

Featuring contributions by leading experts in the field, Aerosols Handbook: Measurement, Dosimetry, and Health Effects, Second Edition offers an up-to-date overview of many aspects of aerosols, f

Author: Lev S. Ruzer

Publisher: CRC Press

ISBN: 9781439855195

Category: Nature

Page: 666

View: 407

With the rapid growth of the nanotechnology industry, the need to understand the biological effects of aerosol exposure has become increasingly important. Featuring contributions by leading experts in the field, Aerosols Handbook: Measurement, Dosimetry, and Health Effects, Second Edition offers an up-to-date overview of many aspects of aerosols, f
Categories: Nature

Report of the OECD Workshop on the Safety of Manufactured Nanomaterials

Report of the OECD Workshop on the Safety of Manufactured Nanomaterials

Are conventional test methods and tools adequate to characterise human health
effects of nanomaterials ? ... How can the biological fate and transport be
measured and assessed ( e.g. adsorption , metabolism , elimination , distribution
and ...

Author:

Publisher:

ISBN: UIUC:30112109106788

Category: Nanotechnology

Page: 149

View: 795

Categories: Nanotechnology

Comprehensive Biomaterials

Comprehensive Biomaterials

In the first study of this system, the pH surrounding the nanoparticles in the
lysosome was measured to be less than 6, which is expected based ...
addressing a number of open issues, including nanoparticle stability in biological
fluids, single-event recognition detection, label-free analysis and classification,
quantification of the analytes of interest, and acute and long-term health effects of
nanomaterials.

Author: Paul Ducheyne

Publisher: Elsevier

ISBN: 9780080552941

Category: Technology & Engineering

Page: 3672

View: 439

Comprehensive Biomaterials brings together the myriad facets of biomaterials into one, major series of six edited volumes that would cover the field of biomaterials in a major, extensive fashion: Volume 1: Metallic, Ceramic and Polymeric Biomaterials Volume 2: Biologically Inspired and Biomolecular Materials Volume 3: Methods of Analysis Volume 4: Biocompatibility, Surface Engineering, and Delivery Of Drugs, Genes and Other Molecules Volume 5: Tissue and Organ Engineering Volume 6: Biomaterials and Clinical Use Experts from around the world in hundreds of related biomaterials areas have contributed to this publication, resulting in a continuum of rich information appropriate for many audiences. The work addresses the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, and strategic insights for those entering and operational in diverse biomaterials applications, research and development, regulatory management, and commercial aspects. From the outset, the goal was to review materials in the context of medical devices and tissue properties, biocompatibility and surface analysis, tissue engineering and controlled release. It was also the intent both, to focus on material properties from the perspectives of therapeutic and diagnostic use, and to address questions relevant to state-of-the-art research endeavors. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance as well as future prospects Presents appropriate analytical methods and testing procedures in addition to potential device applications Provides strategic insights for those working on diverse application areas such as R&D, regulatory management, and commercial development
Categories: Technology & Engineering

Nanoparticle Protein Corona

Nanoparticle   Protein Corona

This book provides a detailed understanding of nanoparticle–protein corona formation, its biological significance and the factors that govern the formation of coronas.

Author: Ashutosh Kumar

Publisher: Royal Society of Chemistry

ISBN: 9781788013918

Category: Science

Page: 293

View: 741

Nanoparticles have numerous biomedical applications including drug delivery, bone implants and imaging. A protein corona is formed when proteins existing in a biological system cover the nanoparticle surface. The formation of a nanoparticle–protein corona, changes the behaviour of the nanoparticle, resulting in new biological characteristics and influencing the circulation lifetime, accumulation, toxicity, cellular uptake and agglomeration. This book provides a detailed understanding of nanoparticle–protein corona formation, its biological significance and the factors that govern the formation of coronas. It also explains the impact of nanoparticle–protein interactions on biological assays, ecotoxicity studies and proteomics research. It will be of interest to researchers studying the application of nanoparticles as well as toxicologists and pharmaceutical chemists.
Categories: Science

Nanotechnology Demystified

Nanotechnology Demystified

A follow-up experiment might measure any potential damage to lung tissue after
inhalation of single-walled carbon ... through inhalation exposure, toxicological
effects of engineered nanoparticles on biological reactions is still a mystery.

Author: Linda Williams

Publisher: McGraw Hill Professional

ISBN: 9780071460231

Category: Technology & Engineering

Page: 343

View: 296

Get up to speed on nanotechnology and the many biological, chemical, physical, environmental, and political aspects of this developing science.
Categories: Technology & Engineering