Lung Inflammation in Health and Disease

Lung Inflammation in Health and Disease

This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease.

Author: Yong-Xiao Wang

Publisher:

ISBN: 3030687503

Category: Electronic books

Page: 384

View: 312

Lung diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma. Each year, tens of millions of people develop and can die from lung infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for some patients. Current treatment options for lung disease are neither always effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
Categories: Electronic books

Lung Inflammation in Health and Disease Volume I

Lung Inflammation in Health and Disease  Volume I

This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease.

Author: Yong-Xiao Wang

Publisher: Springer Nature

ISBN: 9783030630461

Category: Medical

Page: 409

View: 395

Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for those affected. Current treatment options for lung disease are neither effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
Categories: Medical

Lung Inflammation in Health and Disease Volume II

Lung Inflammation in Health and Disease  Volume II

Lung Inflammation in Health and Disease, Volume II, Advances in Experimental Medicine and Biology 1304, https://doi.org/10.1007/978-3-030-68748-9_6 Abbreviations SNPs Single-nucleotide polymorphisms TF ALI Acute lung injury Tissue.

Author: Yong-Xiao Wang

Publisher: Springer Nature

ISBN: 9783030687489

Category: Medical

Page: 384

View: 454

Lung diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma. Each year, tens of millions of people develop and can die from lung infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for some patients. Current treatment options for lung disease are neither always effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
Categories: Medical

Immunity and Inflammation in Health and Disease

Immunity and Inflammation in Health and Disease

This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases.

Author: Shampa Chatterjee

Publisher: Academic Press

ISBN: 9780128054024

Category: Medical

Page: 476

View: 929

Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here. Conceptualizes the key features in natural products which can boost immune function and immune health Explains the intricate mechanistic aspects and balance behind immune health Presents the pathophysiology of several diseases associated with immune system disruption
Categories: Medical

TH17 Cells in Health and Disease

TH17 Cells in Health and Disease

“About 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of ...

Author: Shuiping Jiang

Publisher: Springer Science & Business Media

ISBN: 9781441993717

Category: Medical

Page: 536

View: 144

“About 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of different types of tissue inflammation. However, TH1 / TH2 paradigm could not adequately explain development of certain inflammatory responses which provided impetus for the discovery of a new subset of T cells called TH17 cells. After the discovery of differentiation and transcription factors for TH17 cells, it was clear that TH17 cells represent an independent subset of T cells with specific functions in eliminating certain extracellular pathogens, presumably not adequately handled by TH1 or TH2 cells. The major role of TH17 cells has been described in inducing auto-immune tissue inflammation. The discovery of TH17 cells has expanded the TH1 / TH2 paradigm, and the integration of TH17 cells with TH1 and TH2 effector T cells is beginning to explain the underlying mechanisms of tissue inflammation in a number of infections and auto-immune disease settings.” - From Chapter One by Vijay K. Kuchroo, Harvard University, USA “The recently identified Interleukin 17 (IL-17) cytokine family contributes to immunity to infectious diseases and chronic inflammatory diseases. Further studies on the regulation and function of this important cytokine family may provide better understanding on the roles of the IL-17 family in immune-mediated diseases; such knowledge may lead to the development of immunotherapeutic strategies for treatment of several inflammatory diseases.” - From Chapter Two by Chen Dong, University of Texas and MD Anderson Cancer Center, USA
Categories: Medical

The Pulmonary Endothelium

The Pulmonary Endothelium

This book clearly presents the current body of knowledge and explores how this knowledge may be applied to increase our understanding of disease and develop new types of treatment.

Author: Norbert Voelkel

Publisher: John Wiley & Sons

ISBN: 9780470723616

Category: Medical

Page: 532

View: 129

The Pulmonary Endothelium is a uniquely comprehensive compendium of our current knowledge of the pulmonary endothelium and is the first book dedicated specifically to the subject, offering insights into current and future approaches to management. The text provides the clinician with the most up-to-date information on one of the core physiological processes in airway disease and is an ideal point of reference for both postgraduates and professionals – specialist physicians in pulmonology and allergy and workers in biomedical and pharmaceutical research.
Categories: Medical

Gangliosides in Health and Disease

Gangliosides in Health and Disease

This book brings together world experts in ganglioside structure and function who have been assembled to contribute to this thorough update of the field.

Author:

Publisher: Academic Press

ISBN: 9780128123423

Category: Science

Page: 480

View: 864

Gangliosides in Health and Disease, Volume 156, presents the latest information on Gangliosides, a class of glycolipids that are found on all vertebrate cell surfaces, and are particularly abundant in the brain. Individual chapters in this new volume cover Gangliosides as Toxin Receptors, Gangliosides in Cancer Cell Signaling, Gangliosides in inflammation and neurodegeneration, Gangliosides as functional galectin receptors, Gangliosides in signal transduction, Gangliosides in brain tumor immunology, and Gangliosides in axon regeneration and stability, amongst other related topics. This book brings together world experts in ganglioside structure and function who have been assembled to contribute to this thorough update of the field. Contains accessible content that is ideal for students and researchers alike Written by leading authorities in the field
Categories: Science

Cytokine Frontiers

Cytokine Frontiers

This book guides the reader through the latest research on the cytokine network, covering signaling pathways, control of the immune response, and potential therapeutics.

Author: Takayuki Yoshimoto

Publisher: Springer Science & Business Media

ISBN: 9784431544425

Category: Medical

Page: 396

View: 696

This book guides the reader through the latest research on the cytokine network, covering signaling pathways, control of the immune response, and potential therapeutics. Different cytokines stimulate diverse responses in various phases of inflammation and immunity, including the innate immune response, the generation of effector T cells, and the development of antibodies by the humoral immune system. It is now clear that the pathophysiology of many infectious, autoimmune, allergic, and malignant diseases can be largely explained by which cytokines are induced and subsequently regulate the cellular responses. In clinical medicine, cytokines are involved in a wide spectrum of diseases. This book describes in three parts the properties and roles of 15 key cytokines under physiological and pathological conditions. Part I presents nine cytokines associated with inflammatory disorders, pro-inflammatory cytokines, and the recently identified new helper T (Th) subset: Th17 cells. Part II gives details of three cytokines associated with allergic disorders, including Th2 responses and recently identified types of innate cells. Part III describes three cytokines that are associated with immunological tolerance and anti-inflammation, including regulatory T (Treg) cells, IL-10-producing Treg (Tr1) cells, and inducible IL-35-producing Treg (iTr35) cells. Cytokines are considered to be important as therapeutic targets for specific agonists or antagonists in numerous immune and inflammatory diseases. The ultimate goal of this book is to facilitate the development of therapeutic treatments for such diseases which has been limited by an insufficient understanding of the biology of cytokines and the complicated network that they create.
Categories: Medical

Antioxidants in Health and Disease Volume 2

Antioxidants in Health and Disease Volume 2

In conclusion, taken together, our data show that nootkatone pretreatment prevented lung inflammation assessed by BAL fluid analysis and histopathology and inhibited the production of TNFα and oxidative stress, and the subsequent DNA ...

Author: Maurizio Battino

Publisher: MDPI

ISBN: 9783038429395

Category: Science

Page: 272

View: 941

This book is a printed edition of the Special Issue "Antioxidants in Health and Disease" that was published in Nutrients
Categories: Science

Sex Based Differences in Lung Physiology

Sex Based Differences in Lung Physiology

Accordingly, the book will be a fascinating read for physiologists and clinicians alike. This book provides an overview of the latest experimental work on sex-based differences in lung function and inflammation.

Author: Patricia Silveyra

Publisher: Springer Nature

ISBN: 9783030635497

Category: Medical

Page: 490

View: 894

This book provides an overview of the latest experimental work on sex-based differences in lung function and inflammation. Readers will learn how these differences relate to individual predispositions for the development of lung disease in men and women, and in different stages of their reproductive lives. Further, the book focuses on diseases that predominantly affect women or men, with an emphasis on the physiological mechanisms underlying their pathobiology. In turn, these findings are complemented by chapters on recent studies, which investigate how circulating sex hormone levels impact the lung’s innate immune response to environmental agents and air pollution. The pathogeneses of asthma and viral respiratory infection are also major focus areas. As an outlook, the book also discusses current and future research directions aimed at developing sex-specific therapies for lung disease. To examine these anatomical and physiological differences in the male and female respiratory systems, the authors employ a broad range of methods from molecular and clinical biology. Accordingly, the book will be a fascinating read for physiologists and clinicians alike.
Categories: Medical

Pharmacology and Therapeutics of Airway Disease Second Edition

Pharmacology and Therapeutics of Airway Disease  Second Edition

Written as a concise clinical reference guide covering the current and future airway disease treatments, this text encompasses: pathophysiology of respiratory tract diseases the methods of measuring airway and clinical responses the ...

Author: Kian Fan Chung

Publisher: CRC Press

ISBN: 1420070002

Category: Medical

Page: 468

View: 450

Written as a concise clinical reference guide covering the current and future airway disease treatments, this text encompasses: pathophysiology of respiratory tract diseases the methods of measuring airway and clinical responses the concepts upon which many treatments are used in COPD and asthma conditions the way in which these treatments work, and how new treatments can be discovered and tested in various patient groups state-of-the-art pharmacological and therapeutic approaches in controlling pathophysiological processes in the airways normal and abnormal physiological, biochemical and molecular aspects of the respiratory tract basic mechanisms of inflammatory cell activation and pathophysiology in disease therapeutic ways of controlling inflammation ways of reversing or preventing airflow obstruction, and symptomatic treatments of advanced disease Emphasizing state-of-the-art pharmacological and therapeutic approaches in controlling pathophysiological processes in the airways, Pharmacology and Therapeutics of Airway Disease reviews normal and abnormal physiological, biochemical and molecular aspects of the respiratory tract. Covering the basic mechanisms of inflammatory cell activation and pathophysiology in disease, therapeutic ways of controlling inflammation, reversing or preventing airflow obstruction, and symptomatic treatments of advanced disease.
Categories: Medical

Mitochondrial Function in Lung Health and Disease

Mitochondrial Function in Lung Health and Disease

Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and ...

Author: Viswanathan Natarajan

Publisher: Springer

ISBN: 9781493908295

Category: Medical

Page: 222

View: 450

Mitochondria, often referred to as the “powerhouses” of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis. In addition to generating ATP, mitochondria are involved in regulation of cell cycle, proliferation, free radical production, innate immune responses and apoptosis. Mitochondrial Function in Lung Health and Disease fills the current gap in the literature and outlines the growing clinical relevance of mitochondrial dysfunction. Currently, there is no overview on the role of mitochondria in pulmonary diseases and this volume focuses on the mitochondrial metabolism, redox signaling, and mechanisms of mitochondrial pathways in lung injury, inflammation, repair and remodeling. Furthermore, in addition to their well-recognized role in cellular energy production and apoptosis, mitochondria appear to play a role in many respiratory diseases and lung cancer. Chapters are written by top notch researchers and clinicians and outline the evidence for mitochondrial biogenesis in inhalational lung injury, COPD and asthma.
Categories: Medical

Fishman s Pulmonary Diseases and Disorders Fourth Edition

Fishman s Pulmonary Diseases and Disorders  Fourth Edition

This unparalleled two-volume resource begins with a compelling overview of up-to-date clinical perspectives, along with the scientific basis of lung function in health and disease.

Author: Alfred Fishman

Publisher: McGraw Hill Professional

ISBN: 9780071457392

Category: Medical

Page: 2948

View: 617

A complete guide to the entire field of respiratory medicine--with all-new content and a streamlined new design A Doody's Core Title for 2011! First published in 1980, Fishman's Pulmonary Diseases and Disorders is the classic reference through which pulmonary physicians have gained a commanding look at the diagnosis and treatment of pulmonary diseases and disorders. Edited by the world's foremost authorities, Fishman's Pulmonary Diseases and Disorders covers exactly what you need to know about lung diseases and their management, including sleep-disordered breathing, COPD, emphysema, and lung cancer, as well as new technological advances and imaging techniques. This unparalleled two-volume resource begins with a compelling overview of up-to-date clinical perspectives, along with the scientific basis of lung function in health and disease. It then provides turnkey information on everything from respiratory disease signs and symptoms, to obstructive lung diseases, occupational and environmental disorders, and specific respiratory conditions such as infectious diseases of the lungs and acute respiratory failure. New to the Fourth Edition: Information on recent advancements in many clinically relevant areas of pulmonary medicine Update to the infectious diseases chapters that reflect current practice guidelines and recent antimicrobial developments Clearer connection between fundamental science concepts and clinical applications, which reflect current scientific research Latest information on sleep disorders Review of recent recommendations of the American Thoracic Society and European Respiratory Society for the accurate interpretation of pulmonary function tests Appendices that include a respiratory questionnaire, normal values, and commonly used terms & symbols
Categories: Medical

Fibrocytes in Health and Disease

Fibrocytes in Health and Disease

This volume provides a comprehensive and multidisciplinary overview of fibrocytes, written by the main researchers in the field.

Author: Richard Bucala

Publisher: World Scientific

ISBN: 9789814343718

Category: Medical

Page: 316

View: 384

This volume provides a comprehensive and multidisciplinary overview of fibrocytes, written by the main researchers in the field. It is aimed at a broad audience of scientists and clinicians with an interest in the role of circulating fibrocytes in the etiopathogenesis of different fibrosing disorders, atherosclerosis, autoimmunity, and cancer.
Categories: Medical

The Th2 Type Immune Response in Health and Disease

The Th2 Type Immune Response in Health and Disease

In this book, leading researchers in this exciting and dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for ...

Author: William C. Gause

Publisher: Springer

ISBN: 9781493929115

Category: Medical

Page: 172

View: 126

The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice. This response is complex and includes effector functions that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite. But just as importantly, the type 2 immune response can also mediate tolerance mechanisms, which can mitigate tissue injury as these large multicellular parasites transit through vital organs. The tolerance mechanisms include both tissue repair and immune regulatory effects. These latter aspects of the helminth-induced type 2 immune response are increasingly recognized as a potential resource that can be mined for the development of novel immunotherapies that may enhance wound healing, control of autoimmune and inflammatory diseases and regulation of metabolic homeostasis. In this book, leading researchers in this exciting and dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for diseases associated with inflammation.
Categories: Medical

Sarcoidosis

Sarcoidosis

This reference serves as the most current and comprehensive source on the many aspects of sarcoidosis ranging from the basic science and pathophysiology of the disease to patient evaluation and treatment-providing a detailed analysis of the ...

Author: Robert Baughman

Publisher: CRC Press

ISBN: 9780849361043

Category: Medical

Page: 856

View: 936

This reference serves as the most current and comprehensive source on the many aspects of sarcoidosis ranging from the basic science and pathophysiology of the disease to patient evaluation and treatment-providing a detailed analysis of the pulmonary aspects of the condition including chapters on radiographic manifestations, bronchoalveolar lavage
Categories: Medical

Fibronectin in Health and Disease

Fibronectin in Health and Disease

This timely volume highlights current knowledge concerning the role of fibronectin in human biology and medicine.

Author: Steven E. Carsons

Publisher: CRC Press

ISBN: 9781351080484

Category: Medical

Page: 307

View: 838

This timely volume highlights current knowledge concerning the role of fibronectin in human biology and medicine. It is intended to stimulate further investigation in this area. Emphasized are the importance of fibronectin in the interaction between the cell and its environment; and the role of the fibronectin in the determination of cell behavior in normal physiologic processes, in malignant behavior of cells, and in inflammatory disease. This book is valuable to those in the biomedical community interested in fibronectin, the microenvironment and extracellular matrix. It is also important to those interested in the pathobiochemistry of malignant disease and inflammatory disorders.
Categories: Medical

Mechanisms and Manifestations of Obesity in Lung Disease

Mechanisms and Manifestations of Obesity in Lung Disease

This book is an important new resource for both clinicians and scientists dealing with these new health problems in pulmonary medicine.

Author: Richard A. Johnston

Publisher: Academic Press

ISBN: 9780128135549

Category: Medical

Page: 353

View: 774

Mechanisms and Manifestations of Obesity in Lung Disease is a complete resource on the epidemiology and molecular mechanisms related to obesity and lung disease. Obesity has not simply changed the epidemiology of pulmonary disease, it has had a profound impact on the pathophysiology of common pulmonary diseases. As the obesity epidemic has taken hold throughout the developed world, scientists and clinicians are now challenged with identifying the mechanisms by which obesity alters lung health and the pathogenesis of lung diseases. This book is an important new resource for both clinicians and scientists dealing with these new health problems in pulmonary medicine. Presents an all-in-one resource that describes the impact of obesity on the development and severity of lung disease Details the molecular and immunologic mechanisms by which obesity impacts the pathogenesis and outcomes of lung disease Includes contributions from authors who are internationally recognized as leaders in the area of obesity and lung disease
Categories: Medical

Molecular Pathology of Lung Diseases

Molecular Pathology of Lung Diseases

This major work, complete with 150 illustrations, many of them in color, bridges the gap between clinical pulmonary pathology and basic molecular science.

Author: Dani S. Zander

Publisher: Springer Science & Business Media

ISBN: 9780387724300

Category: Medical

Page: 682

View: 729

This major work, complete with 150 illustrations, many of them in color, bridges the gap between clinical pulmonary pathology and basic molecular science. Through a highly visual approach that features an abundance of tables and diagrams, the book offers a practical disease-based overview. The first two sections of the volume provide the reader with general concepts, terminology and procedures in molecular pathology. The remainder of the volume is subdivided into neoplastic and non-neoplastic lung diseases with detailed chapters covering the current molecular pathology of specific diseases. The book will be essential reading for pathologists, pulmonologists, thoracic surgeons and other health care providers interested in lung disease.
Categories: Medical

Proteases in Health and Disease

Proteases in Health and Disease

In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area.

Author: Sajal Chakraborti

Publisher: Springer Science & Business Media

ISBN: 9781461492337

Category: Science

Page: 403

View: 752

In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be written by established investigators on proteases dysfunctions associated with pathogenesis of different diseases that are known to occur due to deregulation of proteolytic systems. Multidisciplinary approaches demonstrating biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases will be discussed. The book highlights the roles of both intracellular and extracellular proteases in health and disease.
Categories: Science