See chapter 1 of this book for more on Ledley's use of computers in biology, and
for a detailed account of Ledley's career, see November, “Digitiz— ing Life,”
chapter 1. 1 2. November, “Digitizing Life,” 73—74. 1 3 . November argues that
Author: Hallam Stevens
Publisher: University of Chicago Press
Thirty years ago, the most likely place to find a biologist was standing at a laboratory bench, peering down a microscope, surrounded by flasks of chemicals and petri dishes full of bacteria. Today, you are just as likely to find him or her in a room that looks more like an office, poring over lines of code on computer screens. The use of computers in biology has radically transformed who biologists are, what they do, and how they understand life. In Life Out of Sequence, Hallam Stevens looks inside this new landscape of digital scientific work. Stevens chronicles the emergence of bioinformatics—the mode of working across and between biology, computing, mathematics, and statistics—from the 1960s to the present, seeking to understand how knowledge about life is made in and through virtual spaces. He shows how scientific data moves from living organisms into DNA sequencing machines, through software, and into databases, images, and scientific publications. What he reveals is a biology very different from the one of predigital days: a biology that includes not only biologists but also highly interdisciplinary teams of managers and workers; a biology that is more centered on DNA sequencing, but one that understands sequence in terms of dynamic cascades and highly interconnected networks. Life Out of Sequence thus offers the computational biology community welcome context for their own work while also giving the public a frontline perspective of what is going on in this rapidly changing field.
Collectif Mouv ' Séquence d'une vie Sequence of a life Ouvrage dirigé par
Isabelle Galloni d'Istria Publication directed by Isabelle Galloni d'Istria
Photographies : Frédéric Atlan Photos : Frédéric Atlan Traduction en anglais de
Joshua Karson ...
Author: Collectif Mouv'
Publisher: Editions Lansman
Category: Hip-hop dance
Présentation de deux compagnies de danse hip hop, le groupe IF et le groupe MBDT, tous deux formés en 1995, à travers quelques-uns de leurs spectacles dont Séquence d'une vie, créé la même année et remanié en 1997.
The success of sequence analysis for studying life trajectories such as
professional careers or familial life courses is largely ... In sequence analysis, the
analyst is typically interested in comparing groups of sequences desned either by
Author: Herrick BaltscheffskyPublish On: 1986-12-18
Repeats of Base Oligomers ( N = 3n + 1 or 2 ) as Immortal Coding Sequences of
the Primeval World : Construction of ... USA Paper presented by Susumu Ohno at
the Conference on ' Molecular Evolution of Life ' , Lidingö , Sweden , 8–12 ...
Author: Herrick Baltscheffsky
Publisher: Cambridge University Press
An interdisciplinary account of the recent advances made in understanding fundamental molecular aspects of the pre-biological and biological evolution of life.
Thus, even dispensable sequences deserve respect, as they seem to code for
the vital ability for adaptation. ... would think that humans and chimpanzees are
nearly the same species, only well adapted to completely different living
Author: Marcello Barbieri
Publisher: Springer Science & Business Media
Building on a range of disciplines – from biology and anthropology to philosophy and linguistics – this book draws on the expertise of leading names in the study of organic, mental and cultural codes brought together by the emerging discipline of biosemiotics. The volume represents the first multi-authored attempt to deal with the range of codes relevant to life, and to reveal the ubiquitous role of coding mechanisms in both organic and mental evolution.
A review of the sociological research on the life course tHagestad & Neugarten.
in press) indicates that patterns of role transitions across historical time have
been explored mainly through intercohort comparisons. Individual life sequences
Author: Alice S. Rossi
Publisher: Transaction Publishers
Category: Social Science
Gender and the Life Course is an interdisciplinary collection of essays on the lives of women and men as they are affected by history, culture, demography, economic and political stratification, and the biopsychological processes that attend maturation and aging. The book covers three major topics. Part I, which examines gender and the life course in broad historical perspective, includes a summary of recent work in biological ecology and primatology, and an analysis of the persistence of cultural and gender differences in role organization in societies undergoing the transition from agrarianism to industrialism. Other essays trace the changes in sources of household income of industrial workers over the life span, and review temporal and gender differences in life span transitions. Part II examines gender differentiation in a variety of contexts: psychological, psychobiologi-cal, and sociological. Alice Rossi's ASA Presidential Address reviews recent work on fathering and mothering, and argues that sociological explanations of such gender differences need supplementation by concepts from evolutionary theory and the neurosciences. Three essays deal with gender and economy: one shows how gender stratification took hold in the early stages of industrialization in France, another demonstrates the persistence of gender stratification in modern economies, the third focuses on ideology in relation to gender and political power. Part III examines various aspects of the aged in contemporary society, including an argument for an jnterpretive social science that uses diverse methods to improve our ability to describe and interpret many facets of the lives of elderly men and women; a review of the methodology used to study changes in the aged population over time; and an overview of existing data sets that permit further cohort and longitudinal analyses of the aged. The final essays review social policies as they affect the elderly, with particular attention to the fact that most very old people are women, and the impact of the greatly expanded life course for family and kin relations. "Gender and the Life Course "is a state-of-the-art assessment of the best work currently being done' on gender and age a's maturational factors and is essential reading for anyone interested in adult development and gender roles.
Author: International Workshop on the Synthesis and Simulation of Living SystemsPublish On: 1997
Evolutionary Optimization of Biopolymers and Sequence Structure Maps
CHRISTIAN REIDYSa , b , c , STEPHAN Koppa , PETER SCHUSTER 0,6 *
Institut für Molekulare Biotechnologie Beutenbergstraße 11 , D - 07708 Jena ,
Germany Santa ...
Author: International Workshop on the Synthesis and Simulation of Living Systems
Publisher: MIT Press
In addition to presenting the latest work in the field, Artificial Life V includes a retrospective and prospective look at both artificial and natural life with the aim of refining the methods and approaches discovered so far into viable, practical tools for the pursuit of science and engineering goals. May 16-18, 1996 · Nara, Japan Despite all the successes in computer engineering, adaptive computation, bottom-up AI, and robotics, Artificial Life must not become simply a one-way bridge, borrowing biological principles to enhance our engineering efforts in the construction of life-as-it-could-be. We must ensure that we give back to biology in kind, by developing tools and methods that will be of real value in the effort to understand life-as-it-is. Artificial Life V marks a decade since Christopher Langton organized the first workshop on artificial life--a decade characterized by the exploration of new possibilities and techniques as researchers have sought to understand, through synthetic experiments, the organizing principles underlying the dynamics (usually the nonlinear dynamics) of living systems. In addition to presenting the latest work in the field, Artificial Life V includes a retrospective and prospective look at both artificial and natural life with the aim of refining the methods and approaches discovered so far into viable, practical tools for the pursuit of science and engineering goals. Complex Adaptive Systems series
International Conference on Life System Modeling, and Simulation, LSMS 2007,
Shanghai, China, September 14-17, 2007. Proceedings Minrui Fei, George W.
Irwin, Shiwei Ma. Constructing Structural Alignment of RNA Sequences by ...
Author: Minrui Fei
Publisher: Springer Science & Business Media
This book is part of a two-volume work that constitutes the refereed proceedings of the International Conference on Life System Modeling and Simulation, LSMS 2007, held in Shanghai, China, September 2007. Coverage includes modeling and simulation of societies and collective behavior, computational methods and intelligence in biomechanical systems, tissue engineering and clinical bioengineering, computational intelligence in bioinformatics and biometrics, and brain stimulation.
Normal volunteers in the sequence 1 group are administered the drug
intravenously in Period 1 and in the oral formulation in Period 2. The same
number of subjects are assigned to sequence 2 and are given the formulations in
reverse order .
Author: Murray R. Selwyn
Publisher: CRC Press
Let this down-to-earth book be your guide to the statistical integrity of your work. Without relying on the detailed and complex mathematical explanations found in many other statistical texts, Principles of Experimental Design for the Life Sciences teaches how to design, conduct, and interpret top-notch life science studies. Learn about the planning of biomedical studies, the principles of statistical design, sample size estimation, common designs in biological experiments, sequential clinical trials, high dimensional designs and process optimization, and the correspondence between objectives, design, and analysis. Each of these important topics is presented in an understandable and non-technical manner, free of statistical jargon and formulas. Written by a biostatistical consultant with 25 years of experience, Principles of Experimental Design for the Life Sciences is filled with real-life examples from the author's work that you can quickly and easily apply to your own. These examples illustrate the main concepts of experimental design and cover a broad range of application areas in both clinical and nonclinical research. With this one innovative, helpful book you can improve your understanding of statistics, enhance your confidence in your results, and, at long last, shake off those statistical shackles!
“To investigate the phylogeny of benign Theileria parasites, we determined the
complete major piroplasm Surface protein (MPSP) gene sequences for 6 benign
theilerial organisms, including the first from tick. Sequences were analysed ...
Issues in Life Sciences: Bacteriology, Parasitology, and Virology: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Life Sciences—Bacteriology, Parasitology, and Virology. The editors have built Issues in Life Sciences: Bacteriology, Parasitology, and Virology: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Life Sciences—Bacteriology, Parasitology, and Virology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Life Sciences: Bacteriology, Parasitology, and Virology: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
TRANSITIONS, SEQUENCES, TRAJECTORIES, AND INSTITUTIONAL
REGIMES Life-Course policy shapes opportunity structures through institutions
that define the spectrum of individual control over transitions, sequences, and
Author: Walter R. Heinz
Publisher: Transaction Publishers
Category: Social Science
In the last two decades, research on the life course has successfully combined and integrated different and rather isolated fields of social concerns such as: the labor market, family solidarity, education, employment, retirement, and social policy. It has also developed a special focus on crucial problems of sociological research, which includes the understanding of micromacro phenomena, the dynamics of social change, and international comparisons. Contributors to this volume take an international, comparative approach in applying the life course theoretical framework to issues of work and career. Life course research focuses on the relationship between institutions and individuals across the life span and illuminates the impact of modernization on the shaping of biographies. Industrial service societies are characterized by historically new contingencies of living arrangements and biographies. These contingencies differ according to the extent to which life course patterns are regulated by social institutions. In the continental European context, institutional frameworks continue to define the timing and sequencing of transitions across the life course. In less regulated market societies, like the United States and Great Britain, biographies and living arrangements are shaped more by the interaction of markets, social networks, and individual decisions. In active welfare states, institutional resources and rules continue to mediate the effects of social change on the life course. What the editors and contributors to this fine compendium anticipate is a change on the cultural level toward more equality. This trend supports young people, and women in particular, in their expectations concerning an egalitarian relationship. This expectation is not taken for granted from the point of view of the male partner, but has to be negotiated in decisionmaking processes as an issue that concerns the couple as a unit. Thus, the way in which people interact is profoundly impacted by the values and goals of equity demands. Walter R. Heinz is professor of sociology and social psychology, and director, Graduate School of Social Sciences, University of Bremen. Victor W. Marshall is professor of sociology, and director of the Institute on Aging, University of North Carolina at Chapel Hill, Carolina.
The discovery that the nucleotide sequences of the DNA can be used to classify
all life forms has revolutionized our understanding of the relationships between
the most abundant organisms, the bacteria, in particular. In former times, bacteria
Author: Peter Ulmschneider
Publisher: Springer Science & Business Media
This book examines the origins, development and fate of intelligent species in the observable part of our universe. It scrutinizes what kind of information about extraterrestrial intelligent life can be inferred from our own biological, cultural and scientific evolution and the likely future of mankind. There is emphasis on the geological conditions and consequences of life's conquest of land as the pre-condition for the emergence of life with our type of technical intelligence.
The point is that life as we know it is determined in large part by very long
molecules, the so-called macromolecules or biopolymers, like nucleic acid and
proteins, in particular enzymes. These large molecules consist of ordered sequences of ...
Author: Pier Luigi Luisi
Publisher: Columbia University Press
Scientists, philosophers and Buddhist scholars discuss the nature of reality in a book that goes inside a Mind and Life Institute conference. For over a decade, members of the Mind and Life Institute have gathered to discuss questions that are both fundamental and profound: can physics, chemistry, and biology explain the mystery of life? How do our philosophical assumptions influence science and the ethics we bring to biotechnology? And how does an ancient spiritual tradition throw new light on these questions? In Mind and Life, Pier Luigi Luisi reproduces this stimulating cross-cultural dialogue in which world-class scientists, philosophers, and Buddhist scholars develop a holistic approach to the exploration of reality. He also adds scientific background to their presentations, as well as supplementary discussions with prominent participants and attendees. Interviews with His Holiness the Karmapa, the Buddhist monk Matthieu Ricard, and the actor and longtime human rights advocate Richard Gere further enrich the material with personal viewpoints. Conversation topics range from the origin of matter to the nature of evolution, the ethics of genetic manipulation, and the question of consciousness and ethics.
Sequence. Collaborations: Globalisation,. Innovation. Networks. and. the.
Burgeoning. Life. Sciences. in. Asia. Lyndal Halliday Riceis arguably themost
important crop on earth.It istheprimary food for over three billion people or
roughly halfthe ...
Author: Dr Bart Penders
Publisher: Ashgate Publishing, Ltd.
Category: Social Science
In recent years the organisation and practice of collaboration in the life sciences has undergone radical transformations, owing to the advent of big science enterprises, newly developed data gathering and storage technologies, increasing levels of interdisciplinarity, and changing societal expectations for science. Collaboration in the New Life Sciences examines the causes and consequences of changing patterns of scientific collaboration in the life sciences. This book presents an understanding of how and why collaboration in the life sciences is changing and the effects of these changes on scientific knowledge, the work lives and experiences of scientists, social policy and society. Through a series of thematically arranged chapters, it considers the social, technical, and organizational facets of collaboration, addressing not only the rise of new forms of collaboration in the life sciences, but also examining recent developments in two broad research areas: ecology and environment, and the molecular life sciences. With an international team of experts presenting case studies and analyses drawn from the US, UK, Asia and Europe, Collaboration in the New Life Sciences will appeal not only to scholars and students of science and technology studies, but also to those interested in science and social policy, and the sociology of work and organisations.
CHAPTER 5 Organization of Sequences in the Genome Reading the language of
the genes by determining the sequences of their bases is an important approach
to the understanding of life . But because the genomes of plants or animals are ...
Author: Renato Dulbecco
Publisher: Yale University Press
Nobel laureate Renato Dulbecco presents a fascinating overview of the current state of information about life processes, ranging from the characteristics and activities of DNA to sexuality, practical aspects of genetics, communication between cells and between organisms, and the effects of drugs on the brain. He concludes with a provocative discussion of biology and human affairs in which he poses questions about brain programming and its relationship to accountability, freedom of choice, and the future. "An impressive overview of contemporary molecular biology. . . . Dulbecco leads us through virtually all of the exciting currents of recent research, from the origin of life to the biological significance of sexuality, from the most elementary evolutionary concepts to the design of the brain."--Joshua Lederberg, American Society for Microbiology News "Should be of interest to general readers who want to understand the developments that have taken place in biology during the past 30 years as well as to specialists in the field who want to learn more about Dulbecco's perspective."--American Scientist "People [will] enjoy reading and learning about the thread of life in the cell, the mating habits of the bowerbird in New Guinea [and] of the grunion in California, the problem of AIDS, and so on. Read it, enjoy it and learn from it."--David Hall, New Scientist "An excellent resource book for students who have difficulty in understanding the terminology of modern molecular biology; also recommended as a resource to any biologist who has struggled to try to make the discipline comprehensible to the nonscientist."--Choice
A complementary strategy may be to employ sequence ensembles produced by
computational protein design.” “Designed sequences can be more diverse than
natural sequences, possibly avoiding some limitations of experimental databases
Issues in Biological and Life Sciences Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological and Life Sciences Research. The editors have built Issues in Biological and Life Sciences Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biological and Life Sciences Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological and Life Sciences Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
University of Texas Medical Branch, Galveston: PCP consensus sequences of
flaviviruses: correlating variance with vector competence and disease phenotype
Data detailed in 'PCP consensus sequences of flaviviruses: correlating variance
Issues in Life Sciences: Molecular Biology / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Life Sciences—Molecular Biology. The editors have built Issues in Life Sciences: Molecular Biology: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Life Sciences—Molecular Biology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Life Sciences: Molecular Biology: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: National Research CouncilPublish On: 1995-04-06
Computing the S values in some topological ordering requires a total of O(NK)
time, where N = maxj Nl. While multiple sequence comparison algorithms of this
genre are conceptually straightforward, they take an exponential amount of time
Author: National Research Council
Publisher: National Academies Press
As researchers have pursued biology's secrets to the molecular level, mathematical and computer sciences have played an increasingly important role--in genome mapping, population genetics, and even the controversial search for "Eve," hypothetical mother of the human race. In this first-ever survey of the partnership between the two fields, leading experts look at how mathematical research and methods have made possible important discoveries in biology. The volume explores how differential geometry, topology, and differential mechanics have allowed researchers to "wind" and "unwind" DNA's double helix to understand the phenomenon of supercoiling. It explains how mathematical tools are revealing the workings of enzymes and proteins. And it describes how mathematicians are detecting echoes from the origin of life by applying stochastic and statistical theory to the study of DNA sequences. This informative and motivational book will be of interest to researchers, research administrators, and educators and students in mathematics, computer sciences, and biology.
University of Perugia: Characterization, Evolution and Chromosomal Distribution
of Two Satellite DNA Sequence Families in Lathyrus species “DNA clones
containing highly repetitive DNA sequences were selected from partial libraries
Issues in Life Sciences: Cellular Biology / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Life Sciences—Cellular Biology. The editors have built Issues in Life Sciences: Cellular Biology: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Life Sciences—Cellular Biology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Life Sciences: Cellular Biology: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
CHAPTER 12 VEDIC CODES & FIBONACCI SEQUENCES APPLIED TO LIFE
CHANGES the zero that was discovered in India, but little did he know that when
he learned about the nine numbers of the Hindus, he also discovered the key to ...