Introduction to Neuroimaging Analysis

Author: Mark Jenkinson,Michael Chappell

Publisher: Oxford University Press

ISBN: 0198816308

Category: Medical

Page: 208

View: 4108

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MRI has emerged as a powerful way of studying in-vivo brain structure and function in both healthy and disease states. Whilst new researchers may be able to call upon advice and support for acquisition from operators, radiologists and technicians, it is more challenging to obtain anunderstanding of the principles of analysing neuroimaging data. This is crucial for choosing acquisition parameters, designing and performing appropriate experiments, and correctly interpreting the results. This primer gives a general and accessible introduction to the wide array of MRI-based neuroimaging methods that are used in research. Supplemented with online datasets and examples to enable the reader to obtain hands-on experience working with real data, it provides a practical and approachableintroduction for those new to the neuroimaging field. The text also covers the fundamentals of what different MRI modalities measure, what artifacts commonly occur, the essentials of the analysis, and common "pipelines" including brain extraction, registration and segmentation. As it does not require any background knowledge beyond high-school mathematics and physics, this primer is essential reading for anyone wanting to work in neuroimaging or grasp the results coming from this rapidly expanding field.The Oxford Neuroimaging Primers are short texts aimed at new researchers or advanced undergraduates from the biological, medical or physical sciences. They are intended to provide a broad understanding of the ways in which neuroimaging data can be analyzed and how that relates to acquisition andinterpretation. Each primer has been written so that it is a stand-alone introduction to a particular area of neuroimaging, and the primers also work together to provide a comprehensive foundation for this increasingly influential field.
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An Introduction to Resting State FMRI Functional Connectivity

Author: Janine Bijsterbosch,Stephen M. Smith,Christian F. Beckmann

Publisher: Oxford University Press

ISBN: 0198808224

Category:

Page: 156

View: 1878

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Spontaneous resting-state fluctuations in neuronal activity offer insights into the inherent organization of the human brain, and may provide markers for diagnosis and treatment of mental disorders. Resting state functional magnetic resonance imaging (fMRI) can be used to investigate intrinsicfunctional connectivity networks, which are identified based on similarities in the signal measured from different brain regions.From data acquisition to interpretation of results, Introduction to Resting State fMRI Functional Connectivity discusses a wide range of approaches without requiring any previous knowledge of resting state fMRI, making it highly accessible to readers from a broad range of backgrounds.Supplemented with online datasets and examples to enable the reader to obtain hands-on experience working with real data, this primer provides a practical and approachable introduction for those new to the field of resting state fMRI.The Oxford Neuroimaging Primers are short texts aimed at new researchers or advanced undergraduates from the biological, medical or physical sciences. They are intended to provide a thorough understanding of the ways in which neuroimaging data can be analyzed and how that relates to acquisition andinterpretation. Each primer has been written so that it is a stand-alone introduction to a particular area of neuroimaging, and the primers also work together to provide a comprehensive foundation for this increasingly influential field.
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Introduction to Perfusion Quantification using Arterial Spin Labelling

Author: Michael Chappell,Bradley MacIntosh,Thomas Okell

Publisher: Oxford University Press

ISBN: 0192512587

Category: Science

Page: 160

View: 569

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Arterial Spin Labeling (ASL) is an increasingly popular tool to study the brain. What sets it apart from other neuroimaging methods is the combination of quantitative measurements of a physiologically well-defined process, namely perfusion, and a completely non-invasive acquisition methodology. Cerebral perfusion is a critical component to brain health, as it is the primary means to deliver nutrients to support brain function as well as clearing waste products. Hence it is a useful quantity to study in disease where changes in perfusion can indicate regions of the brain that are pathological. Likewise changes in perfusion can be indicative of greater demand for nutrients, such as might be required in response to an increase in neuronal activity. With the advent of a consensus by the ASL community on good practice and a recommendation on robust methods for ASL data collection, more and more researchers are now able to access and use ASL. Despite the technological advances, ASL remains a technique with a low signal to noise ratio. This makes the wise choice of the appropriate analysis methods more important. The aim of this primer is to equip someone new to the field of perfusion imaging and ASL with the knowledge not only to make good choices about ASL acquisition and analysis, but also to understand what choices they are making and why. Examples of analysis applied to real data are given throughout the text and instructions on how to reproduce the analyses are illustrated on the primer website. Written to provide a stand-alone introduction to perfusion qualification using ASL, this primer also works with other texts in the Oxford Neuroimaging Primers series to provide a comprehensive overview of the increasingly influential field of neuroimaging.
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An Introduction to Theories of Learning

Author: Matthew H. Olson,B. R. Hergenhahn

Publisher: Prentice Hall

ISBN: N.A

Category: Education

Page: 492

View: 5453

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For undergraduate and graduate courses in Learning Theory and Learning in departments of psychology and education. Accessible for undergraduates yet thorough enough for graduate students, this comprehensive text defines learning and shows how the learning process is studied. The text places learning in its historical perspective, giving students an appreciation for the figures and theories that have shaped 100 years of learning theory research.
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MEG-EEG Primer

Author: Riitta Hari,Aina Puce

Publisher: Oxford University Press

ISBN: 0190497777

Category: Brain

Page: 352

View: 4073

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This work provides newcomers and more experienced researchers with the very basics of magnetoencephalography (MEG) and electroencephalography (EEG)-two noninvasive methods that can inform about the neurodynamics of the human brain on a millisecond scale. These two closely related methods are addressed side by side, starting from their physical and physiological bases and then advancing to methods of data acquisition, analysis, visualization, and interpretation
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Psychiatric Genetics

A Primer for Clinical and Basic Scientists

Author: Thomas Schulze,Francis McMahon

Publisher: Oxford University Press

ISBN: 0190221976

Category: Medical

Page: 240

View: 7049

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Psychiatrists and other mental health professionals are increasingly confronted with questions about the genetics of psychiatric illness, and the clinical applications of new genetic findings. Psychiatric Genetics: A Primer for Clinical and Basic Scientists addresses these questions through a straightforward introduction to the essentials of psychiatric genetics, complementing more comprehensive textbooks that may seem overwhelming for those new to the field. Written and edited by leaders in the field and the International Society of Psychiatric Genetics (ISPG), the book covers basic epidemiology, recruitment for human studies, phenotyping strategies, formal genetic and molecular genetic studies, statistical genetics, bioinformatics and genomics, pharmacogenetics, the most relevant animal models, and biobanking. Each chapter begins with a list of "take home" points that summarizes content, followed by a brief overview of current knowledge and suggestions for further reading. This Primer is ideal for medical students, psychiatric residents, psychiatrists, and basic neuroscience researchers who are interested in learning about the key concepts and recent advances in the exciting field of psychiatric genetics.
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Research and development in intelligent systems XVII

proceedings of ES2000, the twentieth SGES International Conference on Knowledge Based Systems and Applied Artificial Intelligence, Cambridge, December 2000

Author: Frans Coenen,Max A. Bramer,Alun Preece

Publisher: Springer Verlag

ISBN: 9781852334031

Category: Computers

Page: 388

View: 4193

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The papers in this volume are the refereed technical papers presented at ES2000, the Twentieth SGES International Conference on Knowledge Based Systems and Applied Artificial Intelligence, held in Cambridge in December 2000. The papers in this volume present new and innovative developments in the field, divided into sections on learning, case-based reasoning, knowledge representation, knowledge engineering, and belief acquisition and planning. This is the seventeenth volume in the Research and Development series. The series is essential reading for those who wish to keep up to date with developments in this important field. The Application Stream papers are published as a companion volume under the title Applications and Innovations in Intelligent Systems VIII.
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The New Executive Brain

Frontal Lobes in a Complex World

Author: Elkhonon Goldberg

Publisher: Oxford University Press

ISBN: 9780199758500

Category: Medical

Page: 352

View: 5379

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Elkhonon Goldberg's groundbreaking The Executive Brain was a classic of scientific writing, revealing how the frontal lobes command the most human parts of the mind. Now he offers a completely new book, providing fresh, iconoclastic ideas about the relationship between the brain and the mind. In The New Executive Brain, Goldberg paints a sweeping panorama of cutting-edge thinking in cognitive neuroscience and neuropsychology, one that ranges far beyond the frontal lobes. Drawing on the latest discoveries, and developing complex scientific ideas and relating them to real life through many fascinating case studies and anecdotes, the author explores how the brain engages in complex decision-making; how it deals with novelty and ambiguity; and how it addresses moral choices. At every step, Goldberg challenges entrenched assumptions. For example, we know that the left hemisphere of the brain is the seat of language--but Goldberg argues that language may not be the central adaptation of the left hemisphere. Apes lack language, yet many also show evidence of asymmetric hemispheric development. Goldberg also finds that a complex interaction between the frontal lobes and the amygdale--between a recently evolved and a much older part of the brain--controls emotion, as conscious thoughts meet automatic impulses. The author illustrates this observation with a personal example: the difficulty he experienced when trying to pick up a baby alligator he knew to be harmless, as his amygdala battled his effort to extend his hand. In the years since the original Executive Brain, Goldberg has remained at the front of his field, constantly challenging orthodoxy. In this revised and expanded edition, he affirms his place as one of our most creative and insightful scientists, offering lucid writing and bold, paradigm-shifting ideas.
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