In Vitro Fertilization and Embryo Transfer

In Vitro Fertilization and Embryo Transfer

"The editors of this work have themselves contributed significantly to basic knowledge of the mammalian fertilization process.

Author: Don P. Wolf

Publisher: Springer Science & Business Media

ISBN: 9781461310051

Category: Medical

Page: 408

View: 308

The use of human in vitro fertilization in the management of infertility is the outgrowth of years of laboratory observations on in vitro sperm-egg interaction. "The editors of this work have themselves contributed significantly to basic knowledge of the mammalian fertilization process. The observations of Don Wolf on sperm penetration, the block to polyspermy and, most recently, sperm hyperactivation in the monkey and human, Gregory Kopf's elucidation of the mechanisms of sperm activation during penetration and the reciprocal dialogue between sperm and egg, and Barry Bavister's definition of culture conditions and requirements necessary for in vitro oocyte maturation, fertilization and development in model mammalian systems including nonhuman primates have contributed greatly to our understanding of the mammalian fertilization process. Wolf, Kopf and Gerrity have enjoyed substantial interaction with clinicians in Departments of Obstetrics and Gynecology and have been directly involved with successful IVF programs. Both Wolf and Kopf have served as research scientists in the Division of Reproductive Biology at the University of Pennsylvania, which, for more than 22 years, has fostered co-mingling of clinically oriented and basic science faculty. It is through such interaction, which clearly exists at many institutions including the University of Wisconsin, that the process of technology transfer is best served. Without an exquisitely coordinated laboratory, there can be no consistent success in human in vitro fertilization. Quality control is pivotal, but close collaboration between the laboratory and the clinic is also essential as information is shared and correlated.
Categories: Medical

Human in Vitro Fertilization and Embryo Transfer

Human in Vitro Fertilization and Embryo Transfer

The births of more than 100 apparently normal infants at term following pregnancies initiated by in vitro fertilization and embryo transfer testifies to the successful clinical application of insights obtained from studies in reproductive ...

Author: Don P. Wolf

Publisher: Springer Science & Business Media

ISBN: 9781468447125

Category: Psychology

Page: 440

View: 189

The births of more than 100 apparently normal infants at term following pregnancies initiated by in vitro fertilization and embryo transfer testifies to the successful clinical application of insights obtained from studies in reproductive biology over the last 20 years. In women, these studies have included: 1) characterization of the changes in blood hormone profiles throughout ovulatory menstrual cycles; 2) documentation of the hormonal composition of antral fluid in developing and degenerating preovulatory follicles; 3) correlation of these observations with the state of oocyte maturation and the fertilizability of the oocyte; 4) application of pharmacologic agents for perturbing the normal hormone profiles to regulate the number of preovulatory follicles developing and the time of ovulation; and 5) development of non-invasi ve methods for monitoring follicular development. Optimizing methods for maturing and fertilizing eggs, for moni toring normal development in vi tro, and for transferring and achieving implantation of embryos are continuing concerns of physicians and scientists responsible for extant programs. In addition, all serious students of reproductive biology should critically examine every facet of the processes which must concatenate to assure birth of normal infants following pregnancies achieved by these methods. However, the literature which contains the informational substrate is dispersed widely in a plethora of journals not always readily accessible. Bringing the essentials together facilitates both rapid retrieval of data and access to relevant literature.
Categories: Psychology

In Vitro Fertilization and Embryo Transfer in Primates

In Vitro Fertilization and Embryo Transfer in Primates

Whenever the Oregon Regional Primate Research Center is involved in matters of science, we see a consistent record of exceptional quality in both the work is unequaled and the people who do it.

Author: Don P. Wolf

Publisher: Springer Science & Business Media

ISBN: 9781461227168

Category: Medical

Page: 403

View: 779

It is a genuine honor and a privilege of distinction to provide the foreword for the proceedings that follow. This marvelous symposium reflects the unique qualities of its two principal sponsors. Whenever the Oregon Regional Primate Research Center is involved in matters of science, we see a consistent record of exceptional quality in both the work is unequaled and the people who do it. Likewise, Serono Symposia, USA in assuring a world-class speakers' forum, utterly without taint of commercial influence. The proceedings published herein are a remarkable testimony, not only to the contributors, but to Drs. Brenner, Wolf, Stouffer, and Burnett, who have shepherded its conception, presentation, and publication. Readers will notice immediately one of the universal strengths of this total composition; that is, the diversity of investigational interests among attendees. Presentations on the core topic of primate in vitro fertilization and embryo transfer were joined by specialist presentations in related areas, including human-assisted reproductive technologies, reproductive physiology of the great apes, sperm biology, implantation mechanisms, cryobiology, coculture systems for embryogenesis, micromanipulation technologies, and genetic diagnosis of heritable diseases in the pre embryo. Even though pro-fertility issues understandably dominated this forum, there was significant attention given to fertility-control research, especially the role of primates in this endeavor (more on this subject below).
Categories: Medical

Clinical In Vitro Fertilization

Clinical In Vitro Fertilization

The book describes the conceptual framework and details of technique concerned with in vitro fertilization and embryo transfer (ET).

Author: C. Wood

Publisher: Springer Science & Business Media

ISBN: 9781447133179

Category: Medical

Page: 212

View: 519

Man is entering a new era as a result of advances in human reproduction. Techniques have been developed to assist in the creation of man-artificial insemination and, now, in vitro fertilization (IVF). Soon, other new methods, based upon current advances of the IVF procedure, will develop to improve the quality of human reproduction. The book describes the conceptual framework and details of technique concerned with in vitro fertilization and embryo transfer (ET). Edwards and Steptoe first described the technique of IVF and ET and the subsequent births of two normal babies. Since then, the success rate of the system has been improved by the use of fertility drugs to provide more oocytes and preincubation to mature the oocyte before fertilization. As a result of the continued research from Melbourne and Cambridge, more than 100 babies have been born. A free interchange of information between the Cambridge and Melbourne groups has led to a predictable success rate of 15%-20% per laparoscopy, and infertility centres all over the world are now copying the techniques. It is an appropriate time to inform doctors and scientists to help them understand the various procedures involved in IVF and ET. While many advances will occur in the future, the establishment of high success rates in several of the critical steps in the procedure-oocyte pick-up rate (90%), fertilization (>90%) and early embryo development (70%-90% )-signifies that some of the new techniques are stabilized sufficiently to warrant transmission of information by text, rather than scientific journal.
Categories: Medical

In Vitro Fertilization

In Vitro Fertilization

This comprehensive book covers all aspects of IVF and includes special sections on oocyte and embryo donation as well as gestational carriers, making it ideal for practicing clinicians.

Author: Elizabeth S. Ginsburg

Publisher: Springer Science & Business Media

ISBN: 9781441998484

Category: Health & Fitness

Page: 272

View: 146

In Vitro Fertilization: A Comprehensive Guide represents the next frontier in the integrated clinical and laboratory practice of ART. Uniquely balanced, the book provides the necessary understanding of the key laboratory techniques involved in ART and the complex aspects of clinical care. Featuring the contributions of world leaders in the field, the guide begins with the evaluation of the infertile woman and man. It then moves on to discuss treatment protocols and adjunctive treatments. Techniques for oocyte retrieval, insemination, and culture, and embryo transfer and cryopreservation are explored in detail. This comprehensive book covers all aspects of IVF and includes special sections on oocyte and embryo donation as well as gestational carriers, making it ideal for practicing clinicians. Advances such as pre-implantation genetic diagnosis and screening, in vitro maturation, and means of fertility preservation, including oocyte and ovarian tissue cryopreservation, are also covered. The book concludes with dedicated chapters on quality assessment and improvement, regulation and legal concerns, and stress and ART. Readers will gain complete in-depth knowledge of the most current therapies and techniques, enabling optimal care and counsel of their infertile patients.
Categories: Health & Fitness

Test Tube Babies

Test Tube Babies

Author: David A. Tyckoson

Publisher: Greenwood

ISBN: 0897742060

Category: Health & Fitness

Page: 70

View: 718

Categories: Health & Fitness

In Vitro Fertilization and Embryo Transfer

In Vitro Fertilization and Embryo Transfer

"The editors of this work have themselves contributed significantly to basic knowledge of the mammalian fertilization process.

Author: Don P. Wolf

Publisher: Springer

ISBN: 1461310067

Category: Medical

Page: 408

View: 866

The use of human in vitro fertilization in the management of infertility is the outgrowth of years of laboratory observations on in vitro sperm-egg interaction. "The editors of this work have themselves contributed significantly to basic knowledge of the mammalian fertilization process. The observations of Don Wolf on sperm penetration, the block to polyspermy and, most recently, sperm hyperactivation in the monkey and human, Gregory Kopf's elucidation of the mechanisms of sperm activation during penetration and the reciprocal dialogue between sperm and egg, and Barry Bavister's definition of culture conditions and requirements necessary for in vitro oocyte maturation, fertilization and development in model mammalian systems including nonhuman primates have contributed greatly to our understanding of the mammalian fertilization process. Wolf, Kopf and Gerrity have enjoyed substantial interaction with clinicians in Departments of Obstetrics and Gynecology and have been directly involved with successful IVF programs. Both Wolf and Kopf have served as research scientists in the Division of Reproductive Biology at the University of Pennsylvania, which, for more than 22 years, has fostered co-mingling of clinically oriented and basic science faculty. It is through such interaction, which clearly exists at many institutions including the University of Wisconsin, that the process of technology transfer is best served. Without an exquisitely coordinated laboratory, there can be no consistent success in human in vitro fertilization. Quality control is pivotal, but close collaboration between the laboratory and the clinic is also essential as information is shared and correlated.
Categories: Medical

Practical Manual of In Vitro Fertilization

Practical Manual of In Vitro Fertilization

The Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is a unique, accessible title that provides a complete review of the most well-established and current diagnostic and treatment techniques comprising in ...

Author: Zsolt Peter Nagy

Publisher: Springer Science & Business Media

ISBN: 9781441917805

Category: Medical

Page: 703

View: 361

The Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is a unique, accessible title that provides a complete review of the most well-established and current diagnostic and treatment techniques comprising in vitro fertilization. Throughout the chapters, a uniform structure is employed, including a brief abstract, a keyword glossary, a step-by-step protocol of the laboratory procedures, several pages of expert commentary, key issues of clinical concern, and a list of references. The result is a readily accessible, high quality reference guide for reproductive endocrinologists, urologists, embryologists, biologists and research scientists. The Manual also offers an excellent description of novel procedures that will likely be employed in the near future. An indispensable resource for physicians and basic scientists, the Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is an invaluable reference and addition to the literature.
Categories: Medical

In Vitro Fertilization and Embryo Transfer in Primates

In Vitro Fertilization and Embryo Transfer in Primates

Whenever the Oregon Regional Primate Research Center is involved in matters of science, we see a consistent record of exceptional quality in both the work is unequaled and the people who do it.

Author: Don P. Wolf

Publisher: Springer

ISBN: 1461227178

Category: Medical

Page: 403

View: 857

It is a genuine honor and a privilege of distinction to provide the foreword for the proceedings that follow. This marvelous symposium reflects the unique qualities of its two principal sponsors. Whenever the Oregon Regional Primate Research Center is involved in matters of science, we see a consistent record of exceptional quality in both the work is unequaled and the people who do it. Likewise, Serono Symposia, USA in assuring a world-class speakers' forum, utterly without taint of commercial influence. The proceedings published herein are a remarkable testimony, not only to the contributors, but to Drs. Brenner, Wolf, Stouffer, and Burnett, who have shepherded its conception, presentation, and publication. Readers will notice immediately one of the universal strengths of this total composition; that is, the diversity of investigational interests among attendees. Presentations on the core topic of primate in vitro fertilization and embryo transfer were joined by specialist presentations in related areas, including human-assisted reproductive technologies, reproductive physiology of the great apes, sperm biology, implantation mechanisms, cryobiology, coculture systems for embryogenesis, micromanipulation technologies, and genetic diagnosis of heritable diseases in the pre embryo. Even though pro-fertility issues understandably dominated this forum, there was significant attention given to fertility-control research, especially the role of primates in this endeavor (more on this subject below).
Categories: Medical

A Textbook of In Vitro Fertilization and Assisted Reproduction

A Textbook of In Vitro Fertilization and Assisted Reproduction

This is an enlarged, updated, color-illustrated new edition of the definitive clinical reference on in vitro fertilization and assisted reproduction.

Author: Peter R. Brinsden

Publisher: CRC Press

ISBN: 1850700001

Category: Medical

Page: 576

View: 110

This is an enlarged, updated, color-illustrated new edition of the definitive clinical reference on in vitro fertilization and assisted reproduction. It contains 37 chapters by top-ranked specialists from around the world covering every aspect of investigation and therapeutic options as taught and practiced at the world-famous Bourn Hall Clinic. Large format, double-column pages. Includes bibliographic references, procedures, protocols and information sheets, and index.
Categories: Medical

The Techniques of IVF Made Easy

The Techniques of IVF Made Easy

This latest addition to the ‘Made Easy’ series is also enhanced by 44 full colour images and illustrations throughout the book.

Author: Manish R Pandya

Publisher: JP Medical Ltd

ISBN: 9789351523949

Category: Medical

Page: 303

View: 740

The Techniques of IVF Made Easy covers each step of IVF technology, endocrinology, embryology and ultrasonography in a simple, systematic and practical way.Also includes a DVD-ROM covering the process of In-Vitro Fertilisation from preparation of equipment to embryo transfer, in seventeen steps. This latest addition to the ‘Made Easy’ series is also enhanced by 44 full colour images and illustrations throughout the book.
Categories: Medical