Diagnostic Immunohistochemistry

Diagnostic Immunohistochemistry

Provides quick reference graphs for antibodies throughout the text that illustrate the frequency of immunostaining for a variety of antibodies in tumors.

Author: David J Dabbs

Publisher: Elsevier Health Sciences

ISBN: 9781455700103

Category: Medical

Page: 960

View: 568

Diagnostic Immunohistochemistry presents the latest information and most reliable guidance on immunohistological diagnoses in surgical pathology. David J. Dabbs, MD and other leading experts bring you state-of-the-art coverage on genomic and theranostic applications, molecular anatomic pathology, immunocytology, Non-Hodgkin’s lymphoma, and more. Additional features such as tables discussing antibody specifications, differential diagnosis boxes, ancillary anatomic molecular diagnostics, and full-color histological images ensure user-friendly coverage that makes key information easy to find and apply. This concise and complete resource is today’s indispensable guide to the effective use of immunohistochemical diagnosis. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Presents chapters arranged by organ system for comprehensive coverage of all relevant information in a convenient and intuitive organization. Provides quick reference graphs for antibodies throughout the text that illustrate the frequency of immunostaining for a variety of antibodies in tumors. Includes Key Diagnostic Points boxes in every chapter for a quick summary of text areas that are of particular importance. Features an expert author for each chapter to ensure coverage of the current state of the art. Provides guidance on the role of genomics in identifying genetic and molecular aspects of disease that may affect patient care and therapeutic approaches. Covers theranostic applications to enable you to evaluate therapeutic choices based on immunohistochemical results. Reflects the latest developments in the field through new chapters on molecular anatomic pathology and immunocytology, as well as updated chapters on immunohistology of the prostate, bladder, testis, and kidney and Non-Hodgkin’s lymphoma. Discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval. Presents key differential diagnoses boxes that provide tabular summaries of DDx and algorithms. Features discussions of ancillary anatomic molecular diagnostics as an adjunct to immunohistochemistry for a more well-rounded diagnostic approach.
Categories: Medical

Diagnostic Immunohistochemistry

Diagnostic Immunohistochemistry

Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Author: David J. Dabbs

Publisher:

ISBN: 0323477321

Category: Medical

Page: 944

View: 616

User-friendly and concise, the new edition of this popular reference is your #1 guide for the appropriate use of immunohistochemical stains. Dr. David J. Dabbs and leading experts in the field use a consistent, organ system approach to cover all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Each well-written and well-researched chapter is enhanced with diagnostic algorithms, charts, tables, and superb, full-color histologic images, making this text a practical daily resource for all surgical pathologists. Features a systematic approach to the diagnostic entities of each organ system, including detailed differential diagnoses, diagnostic algorithms, and immunohistograms that depict immunostaining patterns of tumors. Covers many more antigens than other texts, and discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Contains new material on non-lymphoid malignancies, Hodgkin/non-Hodgkin lymphoma, and an expanded chapter on digital imaging and quantitative immunohistochemistry. Provides new grading schemes for several organs, along with new antibodies to cover more genomic immunohistochemistry applications. Offers more emphasis in the breast section of "eyes on" tissue for molecular/IHC prognostics compared to the current trend of gene-expression profiling of breast cancer. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Categories: Medical

Diagnostic Immunohistochemistry E Book

Diagnostic Immunohistochemistry E Book

Each well-written and well-researched chapter is enhanced with diagnostic algorithms, charts, tables, and superb, full-color histologic images, making this text a practical daily resource for all surgical pathologists.

Author: David J Dabbs

Publisher: Elsevier Health Sciences

ISBN: 9780323551601

Category: Medical

Page: 992

View: 214

User-friendly and concise, the new edition of this popular reference is your #1 guide for the appropriate use of immunohistochemical stains. Dr. David J. Dabbs and leading experts in the field use a consistent, organ system approach to cover all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Each well-written and well-researched chapter is enhanced with diagnostic algorithms, charts, tables, and superb, full-color histologic images, making this text a practical daily resource for all surgical pathologists. Features a systematic approach to the diagnostic entities of each organ system, including detailed differential diagnoses, diagnostic algorithms, and immunohistograms that depict immunostaining patterns of tumors. Covers many more antigens than other texts, and discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Contains new material on non-lymphoid malignancies, Hodgkin/non-Hodgkin lymphoma, and an expanded chapter on digital imaging and quantilative immunohistochemistry. Provides new grading schemes for several organs, along with new antibodies to cover more genomic immunohistochemistry applications. Offers more emphasis in the breast section of "eyes on" tissue for molecular/IHC prognostics compared to the current trend of gene-expression profiling of breast cancer.
Categories: Medical

Immunohistochemistry in Tumor Diagnostics

Immunohistochemistry in Tumor Diagnostics

This book offers a comprehensive yet concise overview of immunoprofile of tumors and antibodies used in contemporary surgical pathology, and provides diagnostic algorithms for approaching tumor diagnostics.

Author: Muin S.A. Tuffaha

Publisher: Springer

ISBN: 9783319535777

Category: Medical

Page: 264

View: 441

This book offers a comprehensive yet concise overview of immunoprofile of tumors and antibodies used in contemporary surgical pathology, and provides diagnostic algorithms for approaching tumor diagnostics. Immunohistochemistry has become the most important ancillary technique in diagnostic pathology in the last 20 years, and unlike most books on tumor diagnostics, this volume discusses in details immunohistochemical biomarkers, diagnostic approaches and their pitfalls, as well as the immunoprofile of common tumors throughout all systems of human body. With numerous color figures and detailed flowcharts, it appeals to all pathologists be they young residents in training who want a brief introduction to this technique, or specialists in need of a reliable and comprehensive reference resource in tumors diagnostics.
Categories: Medical

Diagnostic Immunohistochemistry

Diagnostic Immunohistochemistry

Author: Ronald A. DeLellis

Publisher:

ISBN: UOM:39015002408360

Category: Diagnostic immunohistochemistry

Page: 347

View: 329

Categories: Diagnostic immunohistochemistry

Monoclonal Antibodies in Diagnostic Immunohistochemistry

Monoclonal Antibodies in Diagnostic Immunohistochemistry

CHAPTER 1 Theoretical and Technical Considerations for the Use of Monoclonal Antibodies in Diagnostic Immunohistochemistry Howard M. Reisner * University of North Carolina at Chapel Hill Chapel Hill , North Carolina Mark R. Wick ...

Author: Mark Wick

Publisher: CRC Press

ISBN: 0824778383

Category: Medical

Page: 664

View: 638

BRIEF OVERVIEW OF INTERMEDIATE FILAMENT PROTEINS -- NEUROFILAMENT PROTEINS -- GLIAL FILAMENT PROTEIN -- INTERPRETATION OF STUDIES OF HUMAN NERVOUS SYSTEM TUMORS USING ANTIBODIES TO NF AND GF PROTEINS -- FUTURE PROSPECTS FOR THE USE OF PROBES TO NF AND GF PROTEINS IN PATHOLOGY -- CONCLUSIONS -- APPENDIX: SPECIFICITY OF MONOCLONAL ANTIBODIES TO HUMAN NEUROFILAMENT AND GLIAL FILAMENT PROTEINS -- ACKNOWLEDGMENTS -- REFERENCES -- 6 Monoclonal Antibodies to Lymphorecticular and Myeloid Antigens -- METHODS UTILIZED WITH LYMPHOHEMATOPOIETIC MONOCLONAL ANTIBODIES -- T-CELL AND NATURAL KILLER CELL MONOCLONAL ANTIBODIES AND T-CELL MALIGNANCIES -- T-Cell Monoclonal Antibodies -- Natural Killer Cell Antibodies -- T-Cell Malignancies -- B-CELL MONOCLONAL ANTIBODIES AND B-CELL MALIGNANCIES -- B-Cell Monoclonal Antibodies -- B-Cell Malignancies -- Non-T Acute Lymphocytic Leukemia -- Small Noncleaved Cell Malignant Lymphoma -- Chronic Lymphocytic Leukemia and Small Lymphocytic Malignant Lymphoma -- Prolymphocytic Leukemia (Galton's Leukemia) -- Intermediate Differentiation Malignant Lymphoma -- Follicular Malignant Lymphoma with Small Cleaved and/or Large Cleaved Cells -- Diffuse Small Cleaved and Diffuse Mixed Small and Large Cell Malignant Lymphoma -- Diffuse Large Cell and Immunoblastic Malignant Lymphoma -- Hairy Cell Leukemia -- Multiple Myeloma and Plasmacytoid Lymphoma -- HODGKIN'S DISEASE -- MYELOID MONOCLONAL ANTIBODIES AND ACUTE AND CHRONIC MYELOID LEUKEMIA -- Myeloid Monoclonal Antibodies -- Acute Myeloid Leukemia -- Chronic Myelogenous Leukemia -- MONOCLONAL ANTIBODIES USED IN PARAFFIN-EMBEDDED SECTIONS -- Immunoglobulin -- Leu M1 -- LN-1 and LN-2 -- Leu 7 -- Others -- FUTURE DI RECTION -- REFERENCES -- 7 Monoclonal Antibodies to Human Milk Fat Globule Proteins
Categories: Medical

Diagnostic Immunohistochemistry E Book

Diagnostic Immunohistochemistry E Book

For clinical IHC laboratories, technical validation is the sphere that is most relevant to the day- to- day activities of the IHC laboratory. However, a detailed understanding of the role of diagnostic and clinical validation is ...

Author: David J Dabbs, MD

Publisher: Elsevier Health Sciences

ISBN: 9780323721738

Category:

Page:

View: 544

Through five well-regarded editions, Dr. David Dabbs' Diagnostic Immunohistochemistry has set the standard for concise, complete, guidance on the use and interpretation of immunohistochemical stains. The 6th Edition continues this tradition of excellence, bringing you fully up to date with all aspects of this dynamic field. Easy to use and understand, this practical resource distills the large body of information on immunohistochemistry into a single, convenient reference that is invaluable for today's surgical pathologists. Covers all aspects of the field, with an emphasis on the role of genomics in diagnosis and theranostic applications that will better inform treatment options. Includes the latest grading schemes in several organs along with new antibodies to cover more genomic immunohistochemistry applications. Contains current biomarker guidelines and up-to-date references throughout. Offers a systematic approach to the diagnostic entities of each organ system, including detailed differential diagnoses, diagnostic algorithms, and immunohistograms that depict immunostaining patterns of tumors. Contains numerous charts and tables, as well as 1,500 high-quality color histologic images that assist in making a definitive diagnosis. Discusses diagnostic pitfalls through immunohistologic differential diagnosis wherever appropriate so you can provide the most accurate diagnoses. Covers many more antigens than other texts, and discusses antibody specifications with tables that convey information on uses, clones, vendors, sources, antibody titers, and types of antigen retrieval.
Categories:

Diagnostic Immunohistochemistry of the Skin

Diagnostic Immunohistochemistry of the Skin

This book, compiled by an international panel of expert dermatologists represents a concise, yet comprehensive, compendium highlighting the diagnostic and pathogenetic contributions of immunohistochemistry in dermatology.

Author: Jean Kanitakis

Publisher: Hodder Education

ISBN: UOM:39015042792484

Category: Architecture

Page: 311

View: 104

Dermato(patho)logists nowadays greatly rely on the progress of immunohistochemistry, both at the light and electronmicroscopic level. Immunohistochemical techniques not only represent a major diagnostic tool, but they also substantially contribute to our understanding of the aetiopathogenesisof skin diseases. This book, compiled by an international panel of expert dermatologists represents a concise, yet comprehensive, compendium highlighting the diagnostic and pathogenetic contributions of immunohistochemistry in dermatology.
Categories: Architecture

Color Atlas of Immunocytochemistry in Diagnostic Cytology

Color Atlas of Immunocytochemistry in Diagnostic Cytology

This practical handbook will allow for quick reference in the selection and interpretation of markers in specific differential diagnostic in the daily practice of diagnostic cytology. Includes 299 color illustrations.

Author: Parvin Ganjei-Azar

Publisher: Springer

ISBN: 0387321217

Category: Medical

Page: 308

View: 737

This atlas examines the benefits and limitations of immunocytochemistry (ICC) in contemporary cytology. The text addresses offers practical advice on choice of markers, and illustrates the use of ICC in fine needle aspiration and body cavity fluid cytology. This practical handbook will allow for quick reference in the selection and interpretation of markers in specific differential diagnostic in the daily practice of diagnostic cytology. Includes 299 color illustrations.
Categories: Medical

Immunohistochemistry in Diagnostic Dermatopathology

Immunohistochemistry in Diagnostic Dermatopathology

This is an essential text for pathologists, dermatopathologists and residents in pathology and dermatology.

Author: Mai P. Hoang

Publisher: Cambridge University Press

ISBN: 9781108509626

Category: Medical

Page:

View: 341

Rapid and cost-effective immunohistochemistry plays a crucial role in diagnostic pathology. However there are currently very few textbooks dedicated to its role, especially in diagnostic dermatopathology. This comprehensive volume provides a practical guide to the application of immunohistochemistry in dermatopathology and bridges the knowledge gap by updating readers with helpful diagnostic immunostains as well as recently available ones. Organized by lines of differentiation, each chapter includes a synopsis of applicable antibodies, pertinent immunohistochemical panels, summary tables outlining the staining patterns of the entities in the differential diagnosis, and case studies. The twelve chapters cover entities based on lineage including epithelial, melanocytic, lymphoid, adnexal and soft tissue. The role of immunohistochemistry as a screening test for underlying genetic syndromes, immunobullous diseases, detection of infectious agents and therapeutic purpose is also discussed in detail. This is an essential text for pathologists, dermatopathologists and residents in pathology and dermatology.
Categories: Medical

Applied Immunohistochemistry in the Evaluation of Skin Neoplasms

Applied Immunohistochemistry in the Evaluation of Skin Neoplasms

This book provides a comprehensive, state-of-the-art account of the role of immunohistochemistry in the diagnosis of skin tumors, which is crucial given that overlapping histologic features and unusual morphologic changes can lead to ...

Author: Jose A. Plaza

Publisher: Springer

ISBN: 9783319305905

Category: Medical

Page: 385

View: 377

This book provides a comprehensive, state-of-the-art account of the role of immunohistochemistry in the diagnosis of skin tumors, which is crucial given that overlapping histologic features and unusual morphologic changes can lead to considerable diagnostic uncertainty. The book reviews in detail the sensitivity and specificity of commonly available antibodies and their pattern of immunostaining. readers will learn when to order antibodies and how to interpret findings. In addition, prognostic markers are evaluated and emphasis placed on the pitfalls commonly encountered when evaluating these neoplasms. The text is complemented by a wealth of superb images. Helpful histograms and algorithms are included, and clear guidance is provided on the application and interpretation of less commonly used antibodies and immunostains. Applied Immunohistochemistry in the Evaluation of Skin Neoplasms will serve as an extremely valuable resource for practicing dermatopathologists and pathologists.
Categories: Medical

Bone and Soft Tissue Pathology E Book

Bone and Soft Tissue Pathology E Book

The book's pragmatic, well-organized approach—complemented by abundant full-color, high-quality illustrations and at-a-glance tables—makes it easy to access the information you need to quickly and accurately identify pathology specimens ...

Author: Andrew L. Folpe

Publisher: Elsevier Health Sciences

ISBN: 9781437719475

Category: Medical

Page: 480

View: 214

Bone and Soft Tissue Pathology: A Volume in the Diagnostic Pathology Series, by Andrew L. Folpe, MD and Carrie Y. Inwards, MD, packs today's most essential bone and soft tissue pathology know-how into a compact, high-yield format! The book's pragmatic, well-organized approach—complemented by abundant full-color, high-quality illustrations and at-a-glance tables—makes it easy to access the information you need to quickly and accurately identify pathology specimens. The result is a practical, affordable reference for study and review as well as for everyday clinical practice. Reviews normal histology before examining abnormal findings, enabling you to conveniently compare their characteristics in one place at one time. Covers both neoplastic and non-neoplastic conditions of bone and soft tissue to equip you to meet a wide range of diagnostic challenges. Uses a consistent, user-friendly format to explore each entity's clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnoses, and prognostic and therapeutic considerations...making it easy to locate specific information on a particular entity. Features abundant boxes and tables throughout that enhance the presentation and accessibility of the material. Offers nearly 1,000 full-color, high-quality illustrations that demonstrate the key features of a wide variety of pathologic lesions to facilitate greater accuracy in identification of specimens.
Categories: Medical

Immunohistochemistry in Tumor Diagnostics

Immunohistochemistry in Tumor Diagnostics

This book offers a comprehensive yet concise overview of immunoprofile of tumors and antibodies used in contemporary surgical pathology, and provides diagnostic algorithms for approaching tumor diagnostics.

Author: Muin S.A. Tuffaha

Publisher: Springer

ISBN: 3319851888

Category: Medical

Page: 264

View: 887

This book offers a comprehensive yet concise overview of immunoprofile of tumors and antibodies used in contemporary surgical pathology, and provides diagnostic algorithms for approaching tumor diagnostics. Immunohistochemistry has become the most important ancillary technique in diagnostic pathology in the last 20 years, and unlike most books on tumor diagnostics, this volume discusses in details immunohistochemical biomarkers, diagnostic approaches and their pitfalls, as well as the immunoprofile of common tumors throughout all systems of human body. With numerous color figures and detailed flowcharts, it appeals to all pathologists be they young residents in training who want a brief introduction to this technique, or specialists in need of a reliable and comprehensive reference resource in tumors diagnostics.
Categories: Medical

Enzinger and Weiss s Soft Tissue Tumors E Book

Enzinger and Weiss s Soft Tissue Tumors E Book

Navigate through the book quickly thanks to summary outlines at the beginning of each chapter, a color-coded page design, and a consistent approach to every entity.

Author: John R. Goldblum

Publisher: Elsevier Health Sciences

ISBN: 9781455737635

Category: Medical

Page: 1176

View: 312

Enzinger and Weiss's Soft Tissue Tumors is your essential medical reference on the diagnosis of tumors of the skeletal muscles, connective tissue, fat, and related structures. No other source matches Enzinger and Weiss’s scope and depth of coverage in this complex and challenging area of surgical pathology, and no other text contains as much practical information on differential diagnosis. Microscopic findings are correlated with the latest developments in molecular biology, cytogenetics, and immunohistochemistry, providing you with a comprehensive and integrated approach to the evaluation of soft tissue specimens. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compare what you see under the microscope to nearly 2,000 superb images that capture the appearance of a complete range of pathological entities and help you relate their characteristics to their specific classifications. Apply the latest knowledge on FNA biopsy, molecular biology, and cytogenetics. Make rapid and effective decisions with the aid of extensive algorithms, and access information at a glance with abundant tables and graphs. Take advantage of all of the essential clinical and prognostic data on soft tissue tumors that are necessary to formulate complete sign-out reports. Navigate through the book quickly thanks to summary outlines at the beginning of each chapter, a color-coded page design, and a consistent approach to every entity. Apply the latest advances in surgical pathology thanks to major updates on recently identified pathological entities such as soft tissue angiofibroma and CIC-related sarcomas; coverage of the newest molecular diagnostic techniques and immunohistochemical and molecular genetic features of soft tissue tumors; new chapters on GIST and soft tissue tumors showing melanocytic differentiation; and more. Effortlessly find the information you need with a chapter organization based on the newest surgical pathology concepts and classifications of soft tissue tumors.
Categories: Medical

Immunohistochemistry Basics and Methods

Immunohistochemistry  Basics and Methods

This concise yet comprehensive guide to the methods and protocols of immunohistochemistry covers established techniques and current developments in the field such as the use of epitope tags, multiple immunolabeling and diagnostic ...

Author: Igor B. Buchwalow

Publisher: Springer Science & Business Media

ISBN: 3642046096

Category: Medical

Page: 153

View: 861

This concise yet comprehensive guide to the methods and protocols of immunohistochemistry covers established techniques and current developments in the field such as the use of epitope tags, multiple immunolabeling and diagnostic immunohistochemistry.
Categories: Medical

Bone and Soft Tissue Pathology

Bone and Soft Tissue Pathology

Bone and Soft Tissue Pathology: A Volume in the Diagnostic Pathology Series, by Andrew L. Folpe, MD and Carrie Y. Inwards, MD, packs today's most essential bone and soft tissue pathology know-how into a compact, high-yield format!

Author: Andrew L. Folpe

Publisher: Elsevier Health Sciences

ISBN: 9780443066887

Category: Medical

Page: 462

View: 264

Today's most essential bone and soft tissue pathology know-how in a compact, high-yield format. The book is pragmatic and well-organized, and the Expert Consult provides online access to full text and download-ready illustrations.
Categories: Medical

Breast Pathology E Book

Breast Pathology E Book

Breast Pathology, edited by Dr. David J. Dabbs - leading expert in breast pathology and author of the best-selling reference Diagnostic Immunohistochemistry - presents an integrated and highly visual approach to breast pathology.

Author: David J Dabbs

Publisher: Elsevier Health Sciences

ISBN: 9781455737567

Category: Medical

Page: 816

View: 691

Breast Pathology, edited by Dr. David J. Dabbs - leading expert in breast pathology and author of the best-selling reference Diagnostic Immunohistochemistry - presents an integrated and highly visual approach to breast pathology. This in-depth resource combines international perspectives and expertise on genomic and molecular information, clinical presentation, gross and microscopic pathologic findings, radiologic and laboratory diagnosis, immunohistochemistry, and theranostics so you can accurately diagnose the full spectrum of breast diseases. Stay current on hot topics in breast pathology, including theranostic aspects of diagnosis, genomic applications and molecular diagnosis, proper handling of breast specimens to ensure proper sampling and processing, and up-to-date immunohistochemical information. Get a clear picture of how diseases present from over 1750 high-quality images in full color. Tap into the expertise of leading authorities from around the world who offer an integrated approach, incorporating genomic and molecular information, clinical presentation, gross and microscopic pathologic findings, radiologic and laboratory diagnosis, and immunohistochemistry. Find information quickly and easily with the consistent format that features quick reference points at the beginning of each chapter.
Categories: Medical