Cells in Evolutionary Biology

Translating Genotypes into Phenotypes - Past, Present, Future

Author: Brian K. Hall,Sally A. Moody

Publisher: CRC Press

ISBN: 1498787878

Category: Science

Page: 280

View: 7976

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This book is the first in a projected series on Evolutionary Cell Biology, the intent of which is to demonstrate the essential role of cellular mechanisms in transforming the genotype into the phenotype by transforming gene activity into evolutionary change in morphology. This book —Cells in Evolutionary Biology — evaluates the evolution of cells themselves and the role cells have been viewed to play as agents of change at other levels of biological organization. Chapters explore Darwin’s use of cells in his theory of evolution and how Weismann’s theory of the separation of germ plasm from body cells brought cells to center stage in understanding how acquired changes to cells within generations are not passed on to future generations. The study of evolution through the analysis of cell lineages during embryonic development dominated evolutionary cell biology until usurped by the switch to genes as the agents of heredity in the first decades of the 20th century. Discovery that cells exchanged organelles via symbiosis led to a fundamental reevaluation of prokaryotic and eukaryotic cells and to a reorganizations of the Tree of Life. Identification of cellular signaling centers, of mechanisms responsible for cellular patterning, and of cell behavior and cellular condensations as mediating the plasticity that enables phenotypic change during evolution, provided powerful new synergies between cell biology and evolutionary theory and the basis for Evolutionary Cell Biology.
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Animal Models in Light of Evolution

Author: Niall Shanks,C. Ray Greek

Publisher: Universal-Publishers

ISBN: 1599425025

Category: Medical

Page: 444

View: 865

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The central concern of this book is with the "prediction problem" in biomedical research. In particular, the authors examine the use of animal models to predict human responses in drug and disease research. The arguments discussed are drawn from both biological and biomedical theory (with numerous examples and case studies drawn from evolutionary biology, complex systems theory, oncology, teratology, and AIDS research), and analyses of empirical evidence (concerning, for example, data on intra- and inter-species differences revealed by recent results from genome analyses of various species, human population studies, and statistical studies of the predictive utility of animal models). This book comes to the unique conclusion that while animals can be successfully used for many endeavors in science such as basic and comparative research, they cannot be used to predict drug and disease response in humans. The arguments presented are rooted in the history, philosophy, and methodology of biomedical research. This book will be of interest to anyone involved, directly or indirectly, in biomedical research (including physicians, veterinarians and scientists), and anyone interested in the history, philosophy and methodology of science. In contrast to books written by and for the animal rights movement and books written by and for the animal-based research industry, this book honestly examines all sides of the scientific arguments for using animals in science and concludes that each group in turn exaggerates the flaws or strengths of using animals. There are areas in science where animals can be viably used but there are also areas where they cannot be so used. REVIEWS See Philosophies, Ethics, and Humanities in Medicine 17 August 2010
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Issues in Biological, Biochemical, and Evolutionary Sciences Research: 2012 Edition

Author: N.A

Publisher: ScholarlyEditions

ISBN: 148164548X

Category: Science

Page: 775

View: 9432

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Issues in Biological, Biochemical, and Evolutionary Sciences Research: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Macromolecular Research. The editors have built Issues in Biological, Biochemical, and Evolutionary Sciences Research: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Macromolecular Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological, Biochemical, and Evolutionary Sciences Research: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
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Evolutionary Biology of Aging

Author: Michael R. Rose

Publisher: Oxford University Press

ISBN: 9780198022725

Category: Science

Page: 240

View: 5858

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This unique book looks at the biology of aging from a fundamentally new perspective, one based on evolutionary theory rather than traditional concepts which emphasize molecular and cellular processes. The basis for this approach lies in the fact that natural selection, as a powerful determining force, tends to decline in importance with age. Many of the characteristics we associate with aging, the author argues, are more the result of this decline than any mechanical imperative contained within organic structures. This theory in turn yields the most fruitful avenues for seeking answers to the problem of aging, and should be recognized as the intellectual core of gerontology and the foundation for future research. The author ably surveys the vast literature on aging, presenting mathematical, experimental, and comparative findings to illustrate and support the central thesis. The result is the first complete synthesis of this vital field. Evolutionary biologists, gerontologists, and all those concerned with the science of aging will find it a stimulating, strongly argued account.
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Human Evolutionary Biology

Author: Michael P. Muehlenbein

Publisher: Cambridge University Press

ISBN: 1139789007

Category: Social Science

Page: N.A

View: 3981

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Wide-ranging and inclusive, this text provides an invaluable review of an expansive selection of topics in human evolution, variation and adaptability for professionals and students in biological anthropology, evolutionary biology, medical sciences and psychology. The chapters are organized around four broad themes, with sections devoted to phenotypic and genetic variation within and between human populations, reproductive physiology and behavior, growth and development, and human health from evolutionary and ecological perspectives. An introductory section provides readers with the historical, theoretical and methodological foundations needed to understand the more complex ideas presented later. Two hundred discussion questions provide starting points for class debate and assignments to test student understanding.
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Keywords And Concepts In Evolutionary Developmental Biology

Author: N.A

Publisher: Discovery Publishing House

ISBN: 9788183562560

Category:

Page: 492

View: 1673

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Contents: Sting Journalism: Introduction, Forms and Features, Sting Journalism: Ethics, Methods and Hidden Cameras, Sting Operations: Current Perspective, Famous Investigative Journalists and Scandals, Sting Operations in Indian Perspectives.
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The Ideas of Biology

Author: John Tyler Bonner

Publisher: Courier Corporation

ISBN: 0486150860

Category: Science

Page: 192

View: 1936

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Using evolution as the central theme, these concise essays explore the foundations of modern biology, focusing on heredity, embryonic development, and ultimately, relations between organisms and their environment. 24 black-and-white figures.
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Hot Topics in Cell Biology

Author: Jose Becerra,Leonor Santos-Ruiz

Publisher: Chartridge Books Oxford

ISBN: 1909287008

Category: Science

Page: 278

View: 7178

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Summary This book is a definitive overview of the current 'state of the art' in cell biology. It is based on papers presented by leading researchers at the Spanish Society for Cell Biology's XIV Congress - a Congress that strives to achieve scientific excellence. Each participant was asked to prepare a 'mini review' of current and likely future development in their area of research. This book is based on those reviews. As such, it is therefore an analysis of current and future trends. Key Features Contains contributions from some of the world's leading researchers. The book is multidisciplinary, covering almost all topics in cell biology: from basic to applied cell biology, and a wide variety of models: from in vitro to vivo models, ranging from fish to rodents and humans. Each 'mini review' is an easy-read piece, describing the state of the art on a topic with clear language and in a summary format. The mini review format makes the book attractive not only to readers involved in cell biology research and teaching, but also professionals from other disciplines and students. The book takes a truly multidisciplinary approach; it covers a wide array of topics, and the book reflects how cell biology interacts with other disciplines The Editors Jose Becerra is Professor of Cell Biology at the University of Malaga (Spain) since 1989. He has been Dean Secretary, Vice-Dean and Dean of the Faculty of Sciences of Malaga, and is now the Head of the Department of Cell Biology, Genetics and Physiology. From 2001 to 2003 he was the Director of the Andalusian Laboratory of Biology (LAB, Seville), which was converted in the Andalusian Centre for Developmental Biology (CABD) under his term. He is a member of the Technical Committee of the National Stem Cell Bank since 2007, patron of the Board of Trustees of IMABIS Foundation (Mediterranean Institute for the Advance of Biotechnology and Health Research), coordinator of the Biomaterials and Tissue Engineering Area of the the Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), and member of the Direction Committee of the CIBER-BBN. Leonor Santos-Ruiz is Senior Researcher of the CIBER-BBN network at the Andalusian Center for Nanomedicine and Biotechnology (BIONAND). She started her career studying the cellular and molecular basis of lower vertebrates' amazing ability for tissue regeneration, with a special attention to bone and spinal cord repair. Readership Cell biology academics and researchers Contents Introduction Dynamics of cell compartments The intracellular trafficking Cell signaling Autophagy, apoptosis and cell homeostasis Cell biology of aging Plant cell biology Methods in cell biology Applied cell biology Cell biology of cancer Cell therapies and tissue engineering Neurodegeneration and cell biology Nanotechnology and cell biology: challenges and opportunities"
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