A Woman s Initiation

A Woman s Initiation

A Woman's Initiation is a collection of stories about eighteen ordinary women living unexamined, unchallenged lives.

Author: Diana Murphy

Publisher:

ISBN: 0977955605

Category: Biography & Autobiography

Page: 138

View: 113

A Woman's Initiation is a collection of stories about eighteen ordinary women living unexamined, unchallenged lives. Then each was diagnosed with breast cancer. After intially struggling with the intruder in her characteristic style, each woman surrendered, allowing cancer to strip her clean of her old skin, making way for a new, more authentic self to emerge.
Categories: Biography & Autobiography

Arachidonic Acid Metabolism and Tumor Initiation

Arachidonic Acid Metabolism and Tumor Initiation

Cancer Letts.(19): 61–66, 1983. 16. Apaja M: Evaluation of toxicity and carcinogenicity of malonaldehyde. Acta Universitatis Ouluensis, SeriesD. (55):1–61,1980. 17. Marnett LJ, Buck J, Tuttle MA, Basu AK, Bull AW: Distribution and ...

Author: Lawrence J. Marnett

Publisher: Springer Science & Business Media

ISBN: 9781461326113

Category: Medical

Page: 200

View: 569

Prostaglandins, Leukotrienes, and Cancer is a multi-volume series that will focus on an emerging area of cancer research. In 1968, R.H. Williams first reported that elevated prostaglandin levels are present in human medullary car cinoma. Since that time, the concept that arachidonic acid metabolites may be in volved in cancer has expanded to include every aspect of the disease from cell transformation through metastasis. Prostaglandins and leukotrienes are generic terms used to describe a family of bioactive lipids produced from unsaturated fatty acids (principally from arachidonic acid) via the cyclooxygenase and lipoxygenase pathways, respec tively. Cyclooxygenase products consist of diverse products such as prosta glandin E2 (POE), prostacyclin (POI) and thromboxane A2 (TXA), whereas 2 2 2 lipoxygenase products consist of hydroperoxy fatty acids and mono-, di- and tri-hydroxy acids including leukotrienes. The precursor fatty acids for the cyclooxygenase and lipoxygenase pathways are present in cellular phospholipids. This finding established an important control point in their biosynthesis-the release of substrate. This occurs in response to numerous stimuli that act at the cell surface. Dr. Bengl Samuelsson's extensive study of the metabolism of pros taglandins indicated that they are rapidly inactivated on a single pass through pulmonary circulation. Thus, they cannot act as circulating hormones and appear to be made on demand in or in the vicinity of target tissues leading to the concept that prostaglandins are local hormones or autocoids.
Categories: Medical

The Designs of Biological Forms Development and Initiation of Cancer

The Designs of Biological Forms  Development  and Initiation of Cancer

Looking at the uniqueness of each biological form, I assume that the designs of a biological form must be determined by a regulative system coded by certain groups of invariant proteins.

Author: Mirabotalib Kazemie

Publisher: AuthorHouse

ISBN: 9781449010515

Category: Education

Page: 118

View: 214

Looking at the uniqueness of each biological form, I assume that the designs of a biological form must be determined by a regulative system coded by certain groups of invariant proteins. The mechanism in charge of combining these proteins in specific patterns to produce design programs I call primordialization. A design program determines the design and the layout of the structures of the organism during its embryonic development. The patterns of proteins' combinations in primordial programs cannot be shifted one into another by environmental factors. If the amino acid sequence of any of the participating proteins is altered, the design program will obliterate. In case such an alteration happens inside an egg cell, one of the two possibilities is expected to occur. Either the affected cell is no longer viable and dies out, or develops into a creature with indistinct body design. Alteration of the proteins involved in a design program can occur also at any time during an organism's development and later. In such situations the affected cells can turn into a cancer cell
Categories: Education

Evolution in Health and Disease

Evolution in Health and Disease

If repair genes mutate, cells can acquire new genetic alterations, in particular in oncogenes or tumor suppressor genes ... From this picture, it is clear that microevolu- tionary processes can play a major role in cancer initiation and ...

Author: Stephen C. Stearns

Publisher: Oxford University Press

ISBN: 0199207453

Category: Medical

Page: 398

View: 263

This work explores and analyses the ways in which our ancient genes contend with, and influence, modern human life. It offers coverage of the points of contact between evolutionary biology and medical science.
Categories: Medical

Journal of Cancer Research and Clinical Oncology

Journal of Cancer Research and Clinical Oncology

Virchows Arch. B Cell Pathol. 21, 279-298 (1976) Glinos, A.D.: On the applicability of the two-stage concept of initiation and promotion to chemical carcinogenesis in the liver. Acta Un. int. Cancer 20, 571-572 (1964) Glinos, A.D., ...

Author:

Publisher:

ISBN: UCAL:B4933370

Category: Oncology

Page: 330

View: 770

Categories: Oncology

Cancer As Initiation

Cancer As Initiation

The author recounts her experiences with breast cancer, discusses her treatments, and tells how to use cancer as a self-challenge

Author: Barbara Stone

Publisher: Open Court Publishing

ISBN: 0812692748

Category: Health & Fitness

Page: 266

View: 245

The author recounts her experiences with breast cancer, discusses her treatments, and tells how to use cancer as a self-challenge
Categories: Health & Fitness

Handbook of Oxidative Stress in Cancer Therapeutic Aspects

Handbook of Oxidative Stress in Cancer  Therapeutic Aspects

initiation (Prasad and Srivastava 2020). Hydroxyl ion plays a critical role in tumor initiation as it is highly diffusible, easily oxidizes nucleotide base-pairs, and forms DNA adducts (Prasad and Srivastava 2020).

Author: Sajal Chakraborti

Publisher: Springer Nature

ISBN: 9789811654220

Category: Medical

Page: 4078

View: 548

This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy. ​
Categories: Medical

Environmental Health Perspectives

Environmental Health Perspectives

255-268 , 1983 Mouse Skin Tumor Initiation - Promotion and Complete Carcinogenesis Bioassays : Mechanisms and ... mice in an effort to identify carcinogens in these mixtures and to link these materials to the etiology of human cancer .

Author:

Publisher:

ISBN: COLUMBIA:HR01298119

Category: Electronic journals

Page:

View: 665

Categories: Electronic journals

The Beginnings of Cancer in the Cell

The Beginnings of Cancer in the Cell

For understanding the first steps of this interaction, approved methods from quantum theory and solid state physics are applied by the authors. The approach of this book is interdisciplinary. Theoretical models are qualitatively applied.

Author: Janos Ladik

Publisher: Springer

ISBN: UOM:39015017434591

Category: Medical

Page: 216

View: 237

Initiation of cancer in the cell is experimentally related to action of chemicals and radiation. For understanding the first steps of this interaction, approved methods from quantum theory and solid state physics are applied by the authors. The approach of this book is interdisciplinary. Theoretical models are qualitatively applied. Known effects, like oncogene activation, anti-oncogenes, and disturbances of the cell's self-regulation are explained. The authors propose possible points of intervention in the cancer initiation process based on the theoretical considerations.
Categories: Medical