The book provides a comprehensive approach to breast cancer, describing the use of gene profiling techniques to distinguish specific features of individual carcinomas, as well as emerging novel therapeutic approaches to treatment.
Author: Antonio Giordano
Publisher: Springer Science & Business Media
Breast Cancer is the most common tumor in women and the second leading cause of cancer deaths worldwide. Due to breakthroughs in gene profiling, the knowledge of the pathophysiology of the mammary gland had greatly increased over the last decade. In Breast Cancer in the Post Genomic Era, Antonio Giordano, Nicola Normanno, and a panel of international authorities in their field provide a comprehensive approach to the biology, diagnosis, prevention, and treatment of human breast carcinoma. The book provides a comprehensive approach to breast cancer, describing the use of gene profiling techniques to distinguish specific features of individual carcinomas, as well as emerging novel therapeutic approaches to treatment. Additional chapters cover the use of transgenic mice to model human breast cancer and the role of the EGF-CFC family in mammary gland development and neoplasia. Breast Cancer in the Post Genomic-Era succeeds in looking at breast cancer pathogenesis, diagnosis, and treatment under a more comprehensive light, and is a valuable resource for any Radiation or Surgical Oncologist, Cancer Biologist or Pathologist.
... oncology in the post - genomic era : the challenge of Assessment of i - 125
prostate implants by tumor bioeffect . ... between Pelvic malignant
hemangiopericytoma mimicking an ovarian 42 . breast cancer cells and
osteoblastic cells . Kapoor ...
Choosing anticancer drug targets in the post - genomic era . J Clin Invest 1999 ;
104 : 1503-6 . ... Use of chemotherapy plus a monoclonal antibody against HER2
for metastatic breast cancer that overexpresses HER2 . N Engl J Med 2001 ; 344
Cancer researchers strive to more fully understand these changes , and such
information is crucial in cancer diagnostics , prevention and therapeutics . In the post - genomic era , researchers have begun to realize the importance of
Breast cancer susceptibility testing : Realities in the post - genomic era . Nature
Genetics 13 : 16 – 17 . Gifford , Sandra . 1986 . The Meaning of Lumps : A Case
Study of the Ambiguities of Risk . In C . R . Janes , R . Stall and S . M . Gifford (
eds ) ...
Author: Elizabeth Dixon Whitaker
Publisher: Pearson College Division
This reader provides both fascinating comparative ethnographic detail and a theoretical framework for organizing and interpreting information about health. While there are many health-related fields represented in this book, its core discipline is medical anthropology and its main focus is the comparative approach. Cross-cultural comparison gives anthropological analysis breadth while the evolutionary time scale gives it depth. These two features have always been fundamental to anthropology and continue to distinguish it among the social sciences. A third feature is the in-depth knowledge of culture produced by anthropological methods such as participant-observation, involving long-term presence in and research among a study population.The first part of the book explores healing systems in different cultures; the second and third provide a strong grounding in evolutionary and culture-oriented analysis, making clear the connections between biology and culture as they affect health; the final part emphasizes case studies that apply the theoretical principles presented earlier to particular health topics.For medical anthropology, medical sociology, public health, nursing, and medical training professionals.
11143 - G33 Gazing Into a crystal ball - cancer therapy In the post - genomic era .
... This approach has several advan11144 - G33 Comprehensive copy number
and gene expression profiling of the 17q23 ampllcon In human breast cancer .
Proceedings of the National Academy of Sciences of the United States of
America , 94 : 587–592 , 1997 . Friend , S.H. Breast cancer susceptibility testing :
Realities in the post - genomic era . Nature Genetics , 13 : 16-17 , 1996 . Garner ,
The study concluded that even though different gene sets were used for
prognostication in patients with breast cancer, four of the five tested showed
significant agreement in the outcome predictions for individual patients and are
Author: Igor Jurisica
Publisher: Springer Science & Business Media
Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools for analyzing data in the field of medical information science. This, of course, requires analytic tools. Those tools are garnered by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Key challenges in this field include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.
Proceedings of the International Forum on the Scientific Bases of Cancer
Chemoprevention, 31 March-2 April 1996, Bologna, Italy Cesare Maltoni
Morando Soffritti, Walter ... Breast cancer susceptibility testing : realities in the postgenomic era .
Author: Cesare Maltoni
Publisher: Elsevier Science Health Science Division
Hardbound. This volume brings together experts in the fields of molecular biology and carcinogenesis, epidemiologists, pathologists, experimental and clinical oncologists, to review the basic biological knowledge on chemoprevention; and the available results and ongoing studies in the practical application of potential chemopreventive agents for cancer control. On the basis of the available data, the forum further evaluates the potential of these new tools, and indicates future directions for research in this area.
... breast cancer , schizophrenia , bipolar disorder are being identified in the ' post
- genomic ' era . It is also in this context that fierce battles have been waged
within the disability rights movement over reproductive genetic technologies such
Author: Graham Scambler
Publisher: Palgrave MacMillan
Category: Political Science
This book charts the new directions in theory and research in disability studies, giving purpose and shape to the emerging confluence of ideas between traditionally opposed groups.
Golub TR, Slonim DK, Tamayo P. et al: Molecular classification of cancer: class
discovery and class prediction by gene expression monitoring ... Gygi SP, Han
DKM, Gingras AC, et al: Protein analysis by mass spectrometry and sequence
database searching tools for cancer research in the post-genomic era. ... al:
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers.
Second International Research Conference on Familial Cancer, Basel,
September 11-15, 1995 Hansjakob Müller, R. J. Scott, Walter Weber. References
1 3 ... Friend SH : Breast cancer susceptibility testing : Realities in the post - genomic era .
Author: Hansjakob Müller
Publisher: S Karger Ag
Molecular genetics has revolutionized our understanding of the susceptibility to and pathogenesis of cancer and is heralding the era of 'molecular oncology'. This progress is well illustrated by the gain in knowledge accumulated since the release of 'Familial Cancer' in 1985 - known among experts as the 'yellow book'. Cancer genes can now be identified, mapped and sequenced, and this technology has resulted in presymptomatic testing of persons at risk and the development of preventive therapeutic measures. This book provides an update of the latest advances by international experts in the field of hereditary cancer, with special emphasis on the needs of medical practice. The first part is devoted to a discussion of the mechanisms by which predispositions lead to breast and ovarian cancer, intestinal cancer, neoplasia of endocrine glands, and tumors in rare cancer syndromes. Attention is also given to epidemiological aspects of familial cancer occurrence. The second part covers genetic counseling and testing of members of high-risk families, as well as the prevention and treatment of hereditary cancer. Clearly written and well-organized, this book provides essential information not only for molecular geneticists and epidemiologists, but also for genetic counselors and oncologists.
The book provides a comprehensive approach to breast cancer , describing the
use of gene profiling techniques to distinguish specific features of individual
carcinomas , as well as emerging novel ... Breast Cancer in the Post - Genomic Era .
A homologue of Drosophila aurora kinase is oncogenic and amplified in human
colorectal cancers . ... Miyoshi Y , Iwao K , Egawa C , Noguchi S. Association of
centrosomal kinase STK15 / BTAK mRNA expression with chromosomal
instability in human breast cancers . ... R. Protein analysis by mass spectrometry
and sequence database searching : tools for cancer research in the post - genomic era .
deleted FGFR2b constitutively phosphorylates FRS2 in a Epigenomic data ,
genome sequence data , SNP data , copy ligand ... leads to more malignant
phenotype of tumors due to the data are generated in the post - genome era by
using highacquisition ... with a variety of tumors , the FGF autocrine loop . such as breast cancer , gastric cancer , ovarian cancer , endometrial cancer , and prostate
Several papers published evident family histories of cancer and since the
editorial appeared point to an two of whom had late - onset disease . additional
emerging ... Breast cancer susceptibility testing : realities in the post - genomic era .
"Summaries of papers" contained in the journal accompany each issue, 19--
Fulfilling the promise : drug discovery in the post - genomic era . Drug Discov ...
Population screening in the age of genomic medicine . N Engl J ... Mutations and
polymorphisms in the familial early - onset breast cancer ( BRCA1 ) gene . Breast
Announcements 2004 EORTC NATIONAL INSTITUTE CANCER Euroccan
Organization for Research and Treatment ... OF TUMOR BIOLOGY AND
MEDICINE , 2004 21st IATMO CONFERENCE FROM TUMOR POST GENOME
TO CLINICAL ... com 6th MILAN BREAST CANCER CONFERENCE Milan ( Italy )
June 9 - 11 , 2004 Secretariat : Francesca Marangoni ... FOR
ONCODEVELOPMENTAL BIOLOGY AND MEDICINE TUMOR MARKERS IN
THE POSTGENOMIC ERA Helsinki ...
... Annual San Antonio Breast Cancer Symposium L Dunnington San Antonio
Cancer Therapy and Research Center San ... 13 - 17 Apoptosis and Cancer :
Basic Mechanisms and Therapeutic Opportunities in the Post - Genomic Era
Donald Berry et al . , Effect of Screening and Adjuvant Therapy on Mortality from Breast Cancer , New England Journal of ... Kapil , Proteomics - A new player in
the post genomic era , Indian journal of Biochemistry and Biophysics , 39 , 291 ...