Blood Substitutes

Blood Substitutes

This book is not a "proceedings" volume.

Author: Robert M. Winslow

Publisher: Birkhäuser

ISBN: 146128659X

Category: Medical

Page: 210

View: 844

This book is not a "proceedings" volume. Rather the chapters are essays by experts in the field of blood substitutes, invited by the editors to con tribute to the 1996 "Current Issues in Blood Substitutes Research and Development" course given in San Diego, March 18-21. The contributors were selected because of their expertise in areas deemed by the editors to be critical to the advancement of the field. The course, as in past years, is heavily influenced by feedback from par ticipants, and by research in this and related fields. In addition to the didactic lectures (for which these chapters are the foundation), the course also offers the opportunity for presentation of research reports, progress reports from the various companies currently commercializing products, and round table discussions of selected subjects. Thus, we are grateful to past participants for their helpful comments. Production of a book, especially on a short timeline, is not an easy feat.
Categories: Medical

Blood Substitutes Present and Future Perspectives

Blood Substitutes  Present and Future Perspectives

This book contains the selected papers presented at the seventh International Symposium on Blood Substitutes (7th ISBS) held at the International Conference Center of Waseda University in Tokyo on 7-10 September 1997.

Author: E. Tsuchida

Publisher: Elsevier

ISBN: 008052821X

Category: Science

Page: 390

View: 791

This book contains the selected papers presented at the seventh International Symposium on Blood Substitutes (7th ISBS) held at the International Conference Center of Waseda University in Tokyo on 7-10 September 1997. In keeping with the scientific design of the 7th ISBS Symposium, chapters have been carefully selected and organized to showcase the advancements in recent research. This book includes up-to-date clinical results of leading companies which are manufacturing hemoglobin-based or fluorocarbon-based blood substitutes, and covers issues of hemoglobin toxicity and side effects such as vasoconstriction in more detail using carefully designed in vivo and ex vivo techniques. This book is also a collection of various new types of red cell substitutes such as recombinant Hbs, recombinant albumine-lipidheme complex, modified red blood cells, and perfluorochemicals using material science and molecular engineering.
Categories: Science

Blood Substitutes

Blood Substitutes

This book is not a "proceedings" volume.

Author: Robert M. Winslow

Publisher: Springer Science & Business Media

ISBN: 9781461241140

Category: Medical

Page: 210

View: 154

This book is not a "proceedings" volume. Rather the chapters are essays by experts in the field of blood substitutes, invited by the editors to con tribute to the 1996 "Current Issues in Blood Substitutes Research and Development" course given in San Diego, March 18-21. The contributors were selected because of their expertise in areas deemed by the editors to be critical to the advancement of the field. The course, as in past years, is heavily influenced by feedback from par ticipants, and by research in this and related fields. In addition to the didactic lectures (for which these chapters are the foundation), the course also offers the opportunity for presentation of research reports, progress reports from the various companies currently commercializing products, and round table discussions of selected subjects. Thus, we are grateful to past participants for their helpful comments. Production of a book, especially on a short timeline, is not an easy feat.
Categories: Medical

Blood Substitutes

Blood Substitutes

This volume contains a collection of essays by selected authors who are active in the field of blood substitutes research or closely allied disciplines.

Author: Robert M. Winslow

Publisher: Springer Science & Business Media

ISBN: 9781461225768

Category: Science

Page: 206

View: 800

This volume contains a collection of essays by selected authors who are active in the field of blood substitutes research or closely allied disciplines. These essays were delivered as lectures by the authors at the second annual "Current Issues in Blood Substitute Research and Development - 1995" course sponsored jointly by the Departments of Medicine and Bioengineer ing, University of California, San Diego, the National Institutes of Health (NHLBI), and the U.S. Army on March 30, 31, and April 1, 1995 in San Diego. This course had three goals: to present fundaniental discussions of scientific issues critical to further development of artificial oxygen carriers, to provide academicians a forum to discuss their current research, and to provide the companies involved in developing products the opportunity to update the audience on their progress. The organization owes much to the solicited comments of the attendees of the 1994 course. We would like especially to thank the U.S. Army, particularly through the efforts of COL John Hess, who provided significant funding to make publication of this volume possible. In addition, a number of the participating companies provided additional financial support to offset the costs of the course. These include Alliance Pharmaceutical Corp., Hemosol, Nippon Oil and Fat, Northfield Laboratories, and Ortho Biotech.
Categories: Science

Blood Substitutes

Blood Substitutes

LLIS HORWOOD This book reviews progress in the development of synthetic blood substitutes commencing with a historical overview which also establishes the ...

Author: K. C. Lowe

Publisher: John Wiley & Sons

ISBN: 3527265562

Category: Blood substitutes

Page: 187

View: 970

Categories: Blood substitutes

Blood Substitutes

Blood Substitutes

The book provides answers to questions like: why do we need blood substitutes, which are the potential areas of clinical applications and what effects do they have on blood supply and risk of infection?

Author: Thomas Ming Swi Chang

Publisher: S Karger Ag

ISBN: MINN:31951D01794050H

Category: Medical

Page: 141

View: 998

Concentrated effort to develop blood substitutes was only seriously started after 1986 because of public concerns regarding HIV in donor blood. Many publications on blood substitutes have appeared since then, most of them designed mainly for specialists in the field. This first of two volumes on blood substitutes is written by a single author who has 40 years of research experience in this field. It not only keeps specialists up-to-date but also gives non-specialists a comprehensive overview of the most relevant materials. Furthermore, those starting research on blood substitutes will find specific examples of principles and basic laboratory methods. The book provides answers to questions like: why do we need blood substitutes, which are the potential areas of clinical applications and what effects do they have on blood supply and risk of infection? Several chapters are devoted to modified hemoglobin blood substitutes, discussing their composition, functional and efficacy properties as well as their safety and giving an overview of the modified hemoglobin products currently undergoing clinical trials. Other chapters deal with perfluorochemical-based blood substitutes and the future perspectives of blood substitutes in general. Volume 1 ends with a long list of references which should facilitate the search for literature. Liver, heart and trauma surgeons and especially administrators of hospitals, Red Cross societies, health insurers and government agencies will appreciate the clear approach towards a better understanding of this interdisciplinary area.
Categories: Medical

Blood Substitutes Advances in Research and Application 2012 Edition

Blood Substitutes   Advances in Research and Application  2012 Edition

Blood Substitutes—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Blood Substitutes in a concise format.

Author:

Publisher: ScholarlyEditions

ISBN: 9781481618151

Category: Medical

Page: 47

View: 845

Blood Substitutes—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Blood Substitutes in a concise format. The editors have built Blood Substitutes—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Blood Substitutes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Blood Substitutes—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Categories: Medical

Advances in Blood Substitutes

Advances in Blood Substitutes

Each chapter of this volume is a contribution from an expert in the field, chosen by the editors to contribute to the 1997 "Current Issues in Blood Substitute Research and Development" course given in San Diego, March 17-19.

Author: R. Winslow

Publisher: Springer Science & Business Media

ISBN: 9781461219767

Category: Medical

Page: 336

View: 984

Each chapter of this volume is a contribution from an expert in the field, chosen by the editors to contribute to the 1997 "Current Issues in Blood Substitute Research and Development" course given in San Diego, March 17-19. The contributors were selected because of their expertise in areas which the editors believe to be critical to the advancement of the field, and which reflect activity in "hot" areas of relevant research. While there is a continuity in style for the annual course, each year brings changes in emphasis and content. In previous years, we were often not able to provide time for participants to present their views and opinions. Consequently, this year we encouraged discussion after each presentation. These sessions were recorded, transcribed, and are printed with the chapters herein. We believe that the product is very close to the capturing this year's course in print, and trust readers will enjoy reading the always candid and often provocative remarks from the audience. The price paid for inclusion of the discussion transcriptions was a delay in publication. Each author was allowed to edit his/her discussion section as well as the final version of the chapters prior to publication. The changes are mainly for grammar, and we tried, when possible, not to alter the conversational style of these interchanges.
Categories: Medical

Proceedings of the IVth International Symposium on Perfluorochemical Blood Substitutes Kyoto International Conference Hall October 21 22 1978

Proceedings of the IVth International Symposium on Perfluorochemical Blood Substitutes  Kyoto International Conference Hall  October 21 22  1978

International Symposium on Perfluorochemical Blood Substitutes (4, 1978, Kyōto) Takao Mitsunobu. : Proceedings of the IVth International Symposium on ...

Author: International Symposium on Perfluorochemical Blood Substitutes (4, 1978, Kyōto)

Publisher:

ISBN: UIUC:30112045518070

Category: Blood plasma substitutes

Page: 471

View: 122

Categories: Blood plasma substitutes

Red Blood Cell Substitutes

Red Blood Cell Substitutes

The text examines regulatory and socioeconomic aspects of blood substitute products, and global tranfusion practices from the perspective of blood banks and the US Food and Drug Administrations.

Author: Alan Rudolph

Publisher: CRC Press

ISBN: 0824700589

Category: Medical

Page: 504

View: 131

Presents an up-to-date treatment of research strategies, clinical and commercial developments, and regulatory and economic issues pertaining to the formulation of effective and safe red blood cell substitutes. The text examines regulatory and socioeconomic aspects of blood substitute products, and global tranfusion practices from the perspective of blood banks and the US Food and Drug Administrations. It also includes the mechanisms of action and consequences of blood substitute administration.
Categories: Medical

Blood Substitutes

Blood Substitutes

Author: Eishun Tsuchida

Publisher:

ISBN: OCLC:245809494

Category:

Page: 11

View: 654

Categories:

Blood Substitutes Advances in Research and Application 2011 Edition

Blood Substitutes  Advances in Research and Application  2011 Edition

Blood Substitutes: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Blood Substitutes in a compact format.

Author:

Publisher: ScholarlyEditions

ISBN: 9781464969355

Category: Medical

Page: 33

View: 991

Blood Substitutes: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Blood Substitutes in a compact format. The editors have built Blood Substitutes: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Blood Substitutes in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Blood Substitutes: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Categories: Medical

Chemistry and Biochemistry of Oxygen Therapeutics

Chemistry and Biochemistry of Oxygen Therapeutics

The first part of the book deals with the chemistry, biochemistry, physiology and toxicity of oxygen, including chapters on hemoglobin reactivity and regulation; the major cellular and physiological control mechanisms of blood flow and ...

Author: Andrea Mozzarelli

Publisher: John Wiley & Sons

ISBN: 9781119976202

Category: Science

Page: 480

View: 676

Human blood performs many important functions including defence against disease and transport of biomolecules, but perhaps the most important is to carry oxygen – the fundamental biochemical fuel - and other blood gases around the cardiovascular system. Traditional therapies for the impairment of this function, or the rapid replacement of lost blood, have centred around blood transfusions. However scientists are developing chemicals (oxygen therapeutics, or “blood substitutes”) which have the same oxygen-carrying capability as blood and can be used as replacements for blood transfusion or to treat diseases where oxygen transport is impaired. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood links the underlying biochemical principles of the field with chemical and biotechnological innovations and pre-clinical development. The first part of the book deals with the chemistry, biochemistry, physiology and toxicity of oxygen, including chapters on hemoglobin reactivity and regulation; the major cellular and physiological control mechanisms of blood flow and oxygen delivery; hemoglobin and myoglobin; nitric oxide and oxygen; and the role of reactive oxygen and nitrogen species in ischemia/reperfusion Injury. The book then discusses medical needs for oxygen supply, including acute traumatic hemorrhage and anemia; diagnosis and treatment of haemorrhages in "non-surgical" patients; management of perioperative bleeding; oxygenation in the preterm neonate; ischemia normobaric and hyperbaric oxygen therapy for ischemic stroke and other neurological conditions; and transfusion therapy in β thalassemia and sickle cell disease Finally “old”and new strategies for oxygen supply are described. These include the political, administrative and logistic issues surrounding transfusion; conscientious objection in patient blood management; causes and consequences of red cell incompatibility; biochemistry of red blood cell storage; proteomic investigations on stored red blood cells; red blood cells from stem cells; the universal red blood cell; allosteric effectors of hemoglobin; hemoglobin-based oxygen carriers; oxygen delivery by natural and artificial oxygen carriers; cross-linked and polymerized hemoglobins as potential blood substitutes; design of novel pegylated hemoglobins as oxygen carrying plasma expanders; hb octamers by introduction of surface cysteines; hemoglobin-vesicles as a cellular type hemoglobin-based oxygen carrier; animal models and oxidative biomarkers to evaluate pre-clinical safety of extracellular hemoglobins; and academia – industry collaboration in blood substitute development. Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood is an essential reference for clinicians, haematologists, medicinal chemists, biochemists, molecular biologists, biotechnologists and blood substitute researchers.
Categories: Science