Bioconjugate Techniques

Author: Greg T. Hermanson

Publisher: Academic Press

ISBN: 0123822408

Category: Science

Page: 1200

View: 3560


Bioconjugate Techniques, 3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates Features full color illustrations Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented

Soft Matter Self-Assembly

Author: C.N. Likos,F. Sciortino,E. Zaccarelli

Publisher: IOS Press

ISBN: 1614996628

Category: Science

Page: 494

View: 4789


Self-assembly is one of the key concepts in contemporary soft condensed matter. It is an umbrella term which encompasses the various modes of spontaneous organization of micrometer-and submicrometer-sized particles into ordered structures of various degrees of complexity, yet it often relies on remarkably simple interactions and mechanisms. Self-assembly is one of the key principles used by nature to construct living matter, where it frequently takes place in a hierarchical fashion. This book contains the lectures from the Enrico Fermi summer school: Soft Matter Self-assembly, held in Varenna, Italy, in June and July 2015. The primary aim of the school was to cover the most exciting modern aspects of self-assembly in soft condensed matter physics, and to enable Ph.D. students and postdocs to engage with some of the most exciting and current topics in the physics of colloids through a series of mini-courses and seminars hosted by leading figures in the field. Subjects covered include: colloids with directional bonding; pathways of self-organization; self-assembly hydrodynamics; polymer structure and dynamics; liquid-crystal colloid dispersions; and self-organizing nanosystems. The proceedings also include two reprints from Reviews of Modern Physics, and will be of interest to both students and experts in the field.

Silicon Nanomaterials Sourcebook

Hybrid Materials, Arrays, Networks, and Devices, Volume Two

Author: Klaus D. Sattler

Publisher: CRC Press

ISBN: 1351649590

Category: Science

Page: 664

View: 9093


This comprehensive tutorial guide to silicon nanomaterials spans from fundamental properties, growth mechanisms, and processing of nanosilicon to electronic device, energy conversion and storage, biomedical, and environmental applications. It also presents core knowledge with basic mathematical equations, tables, and graphs in order to provide the reader with the tools necessary to understand the latest technology developments. From low-dimensional structures, quantum dots, and nanowires to hybrid materials, arrays, networks, and biomedical applications, this Sourcebook is a complete resource for anyone working with this materials: Covers fundamental concepts, properties, methods, and practical applications. Focuses on one important type of silicon nanomaterial in every chapter. Discusses formation, properties, and applications for each material. Written in a tutorial style with basic equations and fundamentals included in an extended introduction. Highlights materials that show exceptional properties as well as strong prospects for future applications. Klaus D. Sattler is professor physics at the University of Hawaii, Honolulu, having earned his PhD at the Swiss Federal Institute of Technology (ETH) in Zurich. He was honored with the Walter Schottky Prize from the German Physical Society, and is the editor of the sister work also published by Taylor & Francis, Carbon Nanomaterials Sourcebook, as well as the acclaimed multi-volume Handbook of Nanophysics.

Dna Nanotechnology For Bioanalysis: From Hybrid Dna Nanostructures To Functional Devices

Author: Arrabito Giuseppe Domenico,Wang Liqian

Publisher: World Scientific

ISBN: 1786343819

Category: Technology & Engineering

Page: 216

View: 364


This book is intended for non-specialists and students, presenting a unique introduction to the field of DNA nanotechnology. The primary focus is on the extraordinary advantages of specificity and sensitivity obtained by integrating DNA nanostructures in bioanalytical devices. DNA Nanotechnology for Bioanalysis provides a concise and rigorous description for the fabrication of various types of functional nanostructures by optimized software-aided high-yield synthesis. Following this is the explanation of methods to decorate these nanostructures with molecules such as proteins, metal nanoparticles or bioorganic moieties covalently bonded onto DNA via self-assemblage processes. Also provided is a concise review on non-canonical DNA structures (such as G-quadruplexes) and their targeting by small molecules for applications in pharmacology. Finally, it describes the exciting applications of DNA nanostructures in life sciences and nanomedicine, including ultraspecific molecular delivery, control of cell behavior, analysis of cell lysate and DNA-based nano-tools for super-resolution sub-cellular imaging. Contents: Nanotechnology and the Unique Role of DNA (Elisa-C Schöneweiβ, Andreas Jaekel and Barbara Saccà)DNA as Building Material at the Nanoscale: From Concepts to Software-aided Design (Wolfgang Pfeifer, Georg Homa, Giuseppe Arrabito and Barbara Saccà)DNA Sensors for the Detection of Biomolecules and Biochemical Conditions (Birgitta R Knudsen, Anni H Andersen, Magnus Stougaard, Giuseppe Arrabito, Raffaella Suriano and Yi-Ping Ho)DNA Nanostructures in Cell Biology and Medicine (Liqian Wang and Giuseppe Arrabito)Targeting G-quadruplex DNA as Potential Anti-cancer Therapy (Riccardo Bonsignore, Elisa Trippodo and Giampaolo Barone)DNA-aided Super-resolution Bioimaging (JiaJun Li, Giuseppe Arrabito and ZhaoShuai Gao) Readership: Non-specialists, undergraduate students and researchers who are interested in learning the basics of DNA nanotechnology. Keywords: DNA Nanotechnology;Nanostructures;Non-Canonical DNA Structures;G Quadruplexes;Nano-Tools;DNA Origami;DNA Aptamers;Biosensors;Drug DeliveryReview: Key Features: Constitutes a clear introduction to the field of DNA NanotechnologyWritten in an easy and catchy styleContains information of the most recent findings in the world of DNA Nanotechnology (up to 2016), optimal for researchers who want to keep updated with the latest breakthroughs in the field

Advances in Bioorganometallic Chemistry

Author: Toshikazu Hirao,Toshiyuki Moriuchi

Publisher: Elsevier

ISBN: 0128141980

Category: Science

Page: 472

View: 1766


Advances in Bioorganometallic Chemistry examines the synthesis, structure and reactivity of bioorganometallics, their pharmaceutical applications, hydrogenase, vitamin B12-like systems, and metalloproteins. It is written by the top researchers in the field and compiled by editors Toshikazu Hirao and Toshiyuki Moriuchi. Developments in this new field of bioorganometallic chemistry, a hybrid between biology and organometallic chemistry, happen very quickly and this comprehensive reference offers the latest research and findings in the field. The book features a discussion of the synthesis, structure, and reactivity of bioorganometallics, and an examination of hydrogenase-like systems, which were designed to demonstrate catalytic activities and functional properties. Advances in Bioorganometallic Chemistry also includes a discussion of bioorganometallics as they relate to medicinal chemistry, specifically applications of metalloproteins, metalloenzymes, and applications in bioimaging. The book concludes with coverage of vitamin B12-like systems, including the latest developments in derivatives designed to perform bio-inspired catalytic reactions. This work is a valuable resource for chemists working in organometallic chemistry and biology, including biochemists, bioorganic chemists, bioinorganic chemists, as well as pharmaceutical scientists, medicinal chemists, and students studying in these areas. Representative authors: R. H. Fish, T. Moriuchi, T. Hirao, H.-B. Kraatz, H. Takaya, T. P. Curran, G. van Koten. E. Rosenberg, J. M. Lynam, C. G. Hartinger, U. Schatzschneider, G. S. Smith, R. Alberto, S. Takenaka, T. Ihara, T. Hayashi, T. Ueno, P. Schollhammer, Y. Shomura, Y. Hisaeda, H. Shimakoshi, B. Kräutler Provides a balanced overview of the latest research in the field of bioorganometallic chemistry, drawing together the top researchers from around the world Covers topics in the areas of synthesis, reactivity, hydrogenase-like systems, medicinal chemistry, applications of metalloproteins, metalloenzymes, and applications in bioimaging

Photonic Applications in Biosensing and Imaging

12-14 September, 2005, Toronto, Canada

Author: Warren C. W. Chan

Publisher: Society of Photo Optical


Category: Technology & Engineering

Page: 676

View: 1266


Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.

Radiopharmaceutical Chemistry

Author: Jason S. Lewis,Albert D. Windhorst,Brian M. Zeglis

Publisher: Springer

ISBN: 3319989472

Category: Medical

Page: 651

View: 6099


This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.

Issues in Chemistry and General Chemical Research: 2011 Edition

Author: N.A

Publisher: ScholarlyEditions

ISBN: 1464963290

Category: Science

Page: 6580

View: 5733


Issues in Chemistry and General Chemical Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chemistry and General Chemical Research. The editors have built Issues in Chemistry and General Chemical Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chemistry and General Chemical Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Chemistry and General Chemical Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at