BioBuilder

Author: Natalie Kuldell PhD.,Rachel Bernstein,Karen Ingram,Kathryn M Hart

Publisher: "O'Reilly Media, Inc."

ISBN: 1491907541

Category: Science

Page: 238

View: 7290

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Today’s synthetic biologists are in the early stages of engineering living cells to help treat diseases, sense toxic compounds in the environment, and produce valuable drugs. With this manual, you can be part of it. Based on the BioBuilder curriculum, this valuable book provides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories. It also serves as an introduction to the field for science and engineering enthusiasts. Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges. Learn the fundamentals of biodesign and DNA engineering Explore important ethical issues raised by examples of synthetic biology Investigate the BioBuilder labs that probe the design-build-test cycle Test synthetic living systems designed and built by engineers Measure several variants of an enzyme-generating genetic circuit Model "bacterial photography" that changes a strain’s light sensitivity Build living systems to produce purple or green pigment Optimize baker’s yeast to produce ?-carotene
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Non-Conventional Copyright

Do New and Atypical Works Deserve Protection?

Author: Enrico Bonadio,Nicola Lucchi

Publisher: Edward Elgar Publishing

ISBN: 1786434075

Category: Law

Page: N.A

View: 9266

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Copyright law constantly evolves to keep up with societal changes and technological advances. Contemporary forms of creativity can threaten the comfortable conceptions of copyright law as creative people continually find new ways of expressing themselves. In this context, Non-Conventional Copyright identifies possible new spaces for copyright protection. With current copyright law in mind, the contributions explore if the law should be more flexible as to whether new or unconventional forms of expression - including graffiti, tattoos, land art, conceptual art and bio art, engineered DNA, sport movements, jokes, magic tricks, DJ sets, 3D printing, works generated by artificial intelligence, perfume making, typefaces, or illegal and immoral works - deserve protection. Vitally, the contributors suggest that it may be time to challenge some of the basic tenets of copyright laws by embracing more flexible ways to identify protectable works and interpret the current requirements for protection. Additionally, some contributors cast doubts about whether copyright is the right instrument to address and regulate these forms of expression. Contemporary in topic, this thought-provoking book will be essential reading for intellectual property law scholars, practitioners and policymakers. Creative people and those involved in the creative industries will also find this book an engaging read.
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Synthetic Biology: A Very Short Introduction

Author: Jamie A. Davies

Publisher: Oxford University Press

ISBN: 019252528X

Category: Science

Page: 144

View: 5175

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Synthetic biology is one of the 21st century's fastest growing fields of research, as important for technology as for basic science. Building on traditional genetic engineering, which was restricted to changing one or two genes, synthetic biology uses multi-gene modules and pathways to make very significant changes to what cells can do. Synthetic biologists aim to have an impact in fields as diverse as drug manufacture, biofuel production, tackling pollution, and medical diagnostics. Further ahead, synthetic biology may even make possible the long-standing goal of creating new life from non-living starting materials. This Very Short Introduction provides a concise explanation of what synthetic biology is, and how it is beginning to affect many fields of technology. Jamie Davies also discusses the considerable controversies surrounding synthetic biology, from questions over the assumption that engineering concepts can be applied to living systems easily, to scepticism over the claims for commercial promise, fears that the dangers of engineering life are worse than its benefits, and concerns over whether humans should be designing living systems at all. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
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Synthetic Biology, Part A

Methods for Part/Device Characterization and Chassis Engineering

Author: Chris Voigt

Publisher: Academic Press

ISBN: 0123850762

Category: Science

Page: 714

View: 2730

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Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. Encompasses a variety of different approaches, methodologies and disciplines Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation
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Genome Refactoring

Author: Natalie Kuldell,Neal Lerner

Publisher: Morgan & Claypool Publishers

ISBN: 1598299484

Category: Technology & Engineering

Page: 66

View: 2639

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The science of biology celebrates the discovery and understanding of biological systems that already exist in nature. In parallel, the engineering of biology must learn how to make use of our understanding of the natural world to design and build new useful biological systems. "Synthetic biology" represents one example of recent work to engineer biological systems. This emerging field aims to replace the ad hoc process of assembling biological systems by primarily developing tools to assemble reliable-but-complex living organisms from standard components that can later be reused in new combination. The focus of this book is "genome refactoring," one of several approaches to manage the complexity of a biological system in which the goal is to redesign the genetic elements that encode a living form--preserving the function of that form but encoding it with a genome far easier to study and extend. This book presents genome refactoring in two ways: as an important aspect of the emerging field of synthetic biology and as a powerful teaching tool to train would be professionals in the subject. Chapters focus on the overarching goals of synthetic biology and their alignment with the motivations and achievements in genome engineering; the engineering frameworks of refactoring, including genome synthesis, standardization of biological parts, and abstraction; a detailed description of the bacteriophages that have been refactored up to this point; and the methods of refactoring and contexts for that work drawn from the bacteriophage M13. Overall, these examples offer readers the potential for synthetic biology and the areas in need of further research. If successful, synthetic biology and genome refactoring could address any number of persistent societal needs, including sustainable energy, affordable and effective medicine, and green manufacturing practices. Table of Contents: Tools for Genome Engineering and Synthetic Biology / Bacteriophage as Templates for Refactoring / Methods/Teaching Protocols for M13 Reengineering / Writing and Speaking as Biological Engineers / Summary and Future Directions / Appendix A / Appendix B / Appendix C
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