Biobanks and Tissue Research

Biobanks and Tissue Research

The research field of biobanks and tissue research is highly promising. Many projects around the globe are involved in the collection of human tissue and health data for research purposes.

Author: Christian Lenk

Publisher: Springer Science & Business Media

ISBN: 9400716737

Category: Medical

Page: 238

View: 337

The research field of biobanks and tissue research is highly promising. Many projects around the globe are involved in the collection of human tissue and health data for research purposes. These initiatives are driven by the perspective of decisive breakthroughs in the knowledge of the genetic pathways involved in widespread diseases. However, there are considerable ethical and legal challenges to be considered as well. These challenges encompass the use of body material for research purposes, the misuse of genetic and other health data by third parties, trust in science and medicine, concerns regarding privacy, use of genetic data for forensic applications by the state and the police, and regulatory issues. This volume is divided into three parts: the inclusion of the public, the rights of donors and patients, examples and recommendations for the future of tissue research. It presents a comprehensive overview of the most important topics in the field by renowned scholars in medical ethics and biolaw.
Categories: Medical

Human Tissue Research

Human Tissue Research

The use of human tissue for medical research and scientific progress raises many ethical and legal challenges.

Author: Christian Lenk

Publisher: Oxford University Press

ISBN: 9780199587551

Category: Medical

Page: 189

View: 584

The use of human tissue for medical research and scientific progress raises many ethical and legal challenges. This multi-authored interdisciplinary text provides a fascinating insight into interlinking research perspectives and serves as a comprehensive reference to the state of play ethically and legally in Europe.
Categories: Medical

The Ethical and Legal Regulation of Human Tissue and Biobank Research in Europe

The Ethical and Legal Regulation of Human Tissue and Biobank Research in Europe

The results of nine international workshops and three conferences are gathered in this volume.

Author: Katharina Beier

Publisher: Universitätsverlag Göttingen

ISBN: 9783863950316

Category: Biobanks

Page: 170

View: 132

Human tissue and biobank research is of increasing importance for understanding the causes of widespread diseases and developing effective therapies. However, while the success of biobank research depends on the availability of a large number of samples and the consolidation of collections across country borders is very desirable from the perspective of researchers, the legal and ethical requirements for the procurement, storage and use of human tissue samples are rather heterogeneous across different countries. Moreover, the lack of comprehensive supranational regulation on human tissue and biobanking can be seen as posing a serious threat to transnational biomedical research. Against this background, it was one of the aims of the EU-funded Tiss. EU project ("Evaluation of Legislation and Related Guidelines on the Procurement, Storage and Transfer of Human Tissues and Cells in the European Union - an Evidence-Based Impact Analysis") to analyse the ethical and legal regulation of human tissue and biobank research across the 27 European Member States plus Switzerland. The results of nine international workshops and three conferences are gathered in this volume. While the country reports evaluate the implementation of ethical and legal guidelines at a national level, point out their strengths and deficits, and, where required, create an evidence base for the revision of said legislation, the conference reports address more general ethical and legal issues in this field. The volume is completed by a final presentation of project's results.
Categories: Biobanks

Governing Intellectual Property Rights Within Publicly Funded Biobanks

Governing Intellectual Property Rights Within Publicly Funded Biobanks

Guidelines for Human Biobanks and Genetic Research Databases (HBGRDs).
Nuffield Council, Human Tissue Ethical and Legal Issues, 1995. HUGO Ethics
Committee statement on benefit sharing – 9 April 2000. Supra note 43. While the
 ...

Author: Rajam Neethu

Publisher: Kluwer Law International B.V.

ISBN: 9789403506227

Category: Law

Page: 352

View: 500

Governing Intellectual Property Rights Within Publicly Funded Biobanks R. Neethu The boom in biobanks and health databases as research infrastructures have evoked various legal and ethical debates. Since then numerous new developments have emerged such as digitalization, big-data research and artificial intelligence which has important implications for biobank-based research and collaborations. This new paradigm offers new legal challenges for commercial involvement particularly within a publicly funded setting. In this innovative book, the author shows that securing maximum social benefit out of the knowledge emanating from the use of biobank resources lies in managing intellectual property inputs and outputs effectively in keeping with the values core to such research. Focusing on the challenges of involving intellectual property rights (IPRs) particularly in the precompetitive phase of biobank-based research, the book offers an extensive understanding of the role of different IPRs and identifies the gaps in the law and its implications for biobanks. The analysis covers important aspects in relation to biobanks such as: Digital integration and biomedical data storage; Ownership of biological samples; Commercialization and benefit sharing; Partnership models; Public sector research; Disposition of samples; Consent; Cross-border exchange; Trade secrecy; Privacy; Regulatory stewardship; Business strategies; Ethical considerations over biological resources; Patenting of inventions relating to personalized medicine; Ethical parameters within patent law; and Rights regarding genetic data and databases. The book includes observations, case studies and interviews conducted by the author. In conclusion, the author offers cogent recommendations for legal interoperability of IP rules and research practices designed to enhance the ability of biobanks to share, access and reuse data. This book is the first of its kind to explore the organizational and legislative choices for biobanks particularly while engaging in the protection of research results and technology transfer within a publicly funded setting. It will be of substantial interest to all stakeholders in biobanking, especially policymakers, biobankers and researchers working in the field of health law as well as for legal practitioners, academics and patient interest groups.
Categories: Law

Comparative Issues in the Governance of Research Biobanks

Comparative Issues in the Governance of Research Biobanks

Matteo Macilotti Abstract The debate about the requirements of informed consent
in research biobanks has been heated in the last few years. This debate
originates from the peculiarity that characterises the condition of tissue stored in a
 ...

Author: Giovanni Pascuzzi

Publisher: Springer Science & Business Media

ISBN: 9783642331169

Category: Law

Page: 339

View: 172

In the last few years, the boom in biobanking has prompted a lively debate on a host of interrelated legal issues, such as the Gordian knot of the ownership of biological materials, as well as privacy concerns. The latter are due to the difficulty of accepting that biological samples must be completely anonymous without making it practically impossible to exploit their information potential. The issues also include the delicate role and the changing content of the donor’s “informed consent” as the main legal tool that may serve to link the privacy and property interests of donors with the research interests and the set of principles that should be at the core of the biobanking practice. Lastly, the IP issues and the patentability of biological samples as well as the protection of databases storing genetic information obtained from the samples are covered. Collecting eighteen essays written by eminent scholars from Italy, the US, the UK and Canada, this book provides new solutions to these problems. From a comparative viewpoint, it explores the extent to which digital technology may assist in tackling the numerous regulatory issues raised by the practice of biobanking for research purposes. These issues may be considered and analyzed under the traditional paradigms of Property, Privacy, Informed Consent and Intellectual Property.
Categories: Law

The Ethics of Research Biobanking

The Ethics of Research Biobanking

... (2004) Are all biobanks equal? An analysis of the right of remuneration of
donors to tissue and stem cell banks. ... Scientific American 284:42–49 Knoppers
BM, Laberge CM (1995) Research and stored tissues. Persons as sources,
samples ...

Author: Jan Helge Solbakk

Publisher: Springer Science & Business Media

ISBN: 9780387938721

Category: Medical

Page: 357

View: 726

Biobanking, i.e. storage of biological samples or data emerging from such samples for diagnostic, therapeutic or research purposes, has been going on for decades. However, it is only since the mid 1990s that these activities have become the subject of considerable public attention, concern and debate. This shift in climate is due to several factors. The purpose of this book is to investigate some of the ethical, legal and social challenges raised by research biobanking in its different modern forms and formats. The issues raised by research biobanking in its modern form can be divided into four main clusters: how biological materials are entered into the bank; research biobanks as institutions; under what conditions researchers can access materials in the bank, and problems concerning ownership of biological materials and of intellectual property arising from such materials; and how the information is collected and stored, e.g. access-rights, disclosure, confidentiality, data security and data protection.
Categories: Medical

Biobanks

Biobanks

The lack of concern accorded these and other kinds of biobanking activities in the
past was not something limited to the ... Their study reveals that informed consent
procedures for medium size and smaller scale repositories of tissue used for ...

Author: Herbert Gottweis

Publisher: Routledge

ISBN: 9781134090266

Category: Social Science

Page: 236

View: 477

In recent years, a number of large population-based biobanks – genetic databases that combine genetic information derived from blood samples with personal data about environment, medical history, lifestyle or genealogy – have been set up in order to study the interface between disease, and genetic and environmental factors. Unsurprisingly, these studies have sparked a good deal of controversy and the ethical and social implications have been widely debated. Biobanks: Governance in Comparative Perspective is the first book to explore the political and governance implications of biobanks in Europe, the United States, Asia, and Australia. This book explores: the interrelated conditions needed for a biobank to be created and to exist the rise of the new bio-economy the redefinition of citizenship accompanying national biobank developments This groundbreaking book makes clear that biobanks are a phenomenon that cannot be disconnected from considerations of power, politics, and the reshaping of current practices in governance. It will be a valuable read for scholars and students of genetics, bioethics, risk, public health and the sociology of health and illness.
Categories: Social Science

Biobanking in the 21st Century

Biobanking in the 21st Century

This book will be of interest to a wide range of readers including: academics, students, volunteers and advocates of patients’ rights.

Author: Feridoun Karimi-Busheri

Publisher: Springer

ISBN: 9783319205793

Category: Science

Page: 186

View: 609

Biobanking, an emerging field supported by academia, industry and health administrators alike, is distinctly different today from the practice that once defined it. The science of Biobanking, which initially involved simply storing blood or tissue samples in a freezer, is now a highly sophisticated field of research, and expected to grow exponentially over the next decade or two. This book aims to serve the purpose of further enriching the available literature on Biobanking, by offering unique and more useful collection of ideas for the future. The book outlines the experiences of developing modern Biobanking repositories in different countries, whilst covering specific topics regarding the many aspects of Biobanking. This book will be of interest to a wide range of readers including: academics, students, volunteers and advocates of patients’ rights.
Categories: Science

Principles and Practice in Biobank Governance

Principles and Practice in Biobank Governance

2005), which canbe usedby many different researchers formanydifferent
purposes. TheIrish Prostate Cancer Research Consortium (PCRC)has
developedaresearch biobankfor prostate cancer tissue, blood, urineand DNA.
Ensuring the ...

Author: Dr Jane Kaye

Publisher: Ashgate Publishing, Ltd.

ISBN: 9781409492108

Category: Social Science

Page: 316

View: 574

Rapid technological advances, the establishment of large-scale biobanks, and the exchange of data across international boundaries raise a variety of questions for regulators struggling with the problem of how to govern such stores of information and the processes connected with them. Engaging with the pressing issues of privacy, consent, access to data, and benefit sharing, Principles and Practice in Biobank Governance draws together the latest empirical research from the UK, Europe, America, Australia and Asia to focus on these challenges. Current models of governance are critiqued, principles and policies are debated, and new models and theoretical frameworks are presented through this intellectually stimulating, informative volume. This truly international volume offers new insights from a range of disciplinary perspectives and will be essential reading for policy makers and scholars across a range of social sciences, including sociology, bioethics, law and social policy.
Categories: Social Science

Transparenz

Transparenz

This emphasis on transparency has particular meaning in the context of
establishing biobank projects1 and biobanking research, given the cultural and
political significance of substance and tissue donation and the linkages that are
made ...

Author: Stephan A. Jansen

Publisher: Springer-Verlag

ISBN: 9783531924663

Category: Social Science

Page: 436

View: 201

Der Ruf nach Transparenz ist mit Beginn des 21. Jahrhunderts – nicht zuletzt aufgrund von Krisen, Terrorismus, Korruption – lauter geworden. Transparenz erscheint als Heilmittell mit der Komplexität unserer unübersichtlichen und undurchsichtigen Welt umzugehen. Aber ist die Forderung nicht zu durchsichtig? Ist umgekehrt Intransparenz immer schon ein Hinweis auf ein Problem oder auf eine besondere Ressource? Ist in einer medialisierten Gesellschaft auch der persönliche Alltag nicht zunehmend eine Ausverhandlung zwischen Transparenz und privatem Rückzug – bei „sozialen Medien“, „gläsernen Kunden bzw. Mitarbeitern“? Oszilliert Transparenz nicht immer zwischen Überwachung und Sicherheit – vom Nacktscanner bis zur Anti-Korruption? Der sechste Jahresband der Zeppelin Universität befasst sich mit diesen und vielen anderen Fragen rund um Transparenz und nimmt eine differenzierte Verortung von Transparenz in unterschiedlichen Lebensbereichen von Wirtschaft, Kultur und Politik vor. Die Beiträge des Bandes spannen einen Bogen von der Transparenz in privaten wie öffentlichen Organisationen über die Transparenz politischer Rhetorik bis hin zur Transparenz im alltäglichen Konsum.
Categories: Social Science

Biomedical Informatics in Translational Research

Biomedical Informatics in Translational Research

3.1.2 Overview of Current Tissue Banking Practices Human tissue repositories
have existed in the United States in ... efficiency, and accessibility of Swedish
biobanks for health-related research as well as for clinical care and treatment” [7].

Author: Hai Hu

Publisher: Artech House

ISBN: 9781596930391

Category: Computers

Page: 264

View: 213

This trailblazing resource on biomedical informatics provides medical researchers with innovative techniques for integrating and federating data from clinical and molecular studies. This volume helps researchers manage data, expedite their efforts, and make the most of targeted basic research.
Categories: Computers

Issues in Cancer Treatment and Therapy 2011 Edition

Issues in Cancer Treatment and Therapy  2011 Edition

Memorial Sloan-Kettering Cancer Center, New York City: Biobanking of human
pancreas cancer tissue: impact of ex-vivo procurement times on RNA quality New
research, 'Biobanking of human pancreas cancer tissue: impact of ex-vivo ...

Author:

Publisher: ScholarlyEditions

ISBN: 9781464967283

Category: Medical

Page: 304

View: 370

Issues in Cancer Treatment and Therapy / 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Cancer Treatment and Therapy in a concise format. The editors have built Issues in Cancer Treatment and Therapy: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer Treatment and Therapy in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Cancer Treatment and Therapy: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Categories: Medical

Ethical Issues in Governing Biobanks

Ethical Issues in Governing Biobanks

Requirements imposed on researchers: transfer of samples and sharing of
results Biobanks and biological repositories are primarily ... Finally, human tissue
isoften seenas a precious resource, whichis difficultto collect andto store:
misusing or ...

Author: Alexander M. Capron

Publisher: Ashgate Publishing, Ltd.

ISBN: 9781409496311

Category: Science

Page: 268

View: 905

Population genomics research drawing on genetic databases has expanded rapidly, with some of this information being combined in 'biobanks'. Managing this information in an appropriate way is a highly complex ethical issue in the health policy arena. This book combines theoretical and empirical research to analyze the areas of conflict and consensus in the regulatory and ethical frameworks that have been developed to govern biobanks. Ethicists from the Department of Ethics, Trade, Human Rights and Health Law (ETH) of the World Health Organization, the Institute of Biomedical Ethics of Geneva University and the Institute of Biomedical Ethics of the University of Zurich, with the support of the Geneva International Academic Network (GIAN), examine the conditions under which genetic databases can be established, kept, and made use of in an ethically acceptable way. In addition to a comprehensive review of the scientific literature and a comparative analysis of existing normative frameworks, they present the results of in-depth interviews with experts around the world concerning the most unresolved and controversial issues. The results of that study, combined with their normative analysis, leads to recommendations for a better international framework.
Categories: Science

Designing Clinical Research

Designing Clinical Research

Large biobanks of blood and tissue samples allow future studies to be carried out
without the collection of additional samples. Research on previously collected
specimens and data offers no physical risks to participants. However, there are ...

Author: Stephen B. Hulley

Publisher: Lippincott Williams & Wilkins

ISBN: 0781782104

Category: Medical

Page: 367

View: 172

This third edition sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology and offers an updated syllabus for conducting a clinical research workshop.
Categories: Medical

Nutrition Research Methodologies

Nutrition Research Methodologies

... think-aloud protocols, 158 biobanks, in nutrition research BBMRI-ERIC, 142
Biobanking and Biomolecular Resources ... tissues, 142 multinational study
designs, 143 OECD biobank definition, 142 research infrastructures, for nutrition
and ...

Author: Julie A. Lovegrove

Publisher: John Wiley & Sons

ISBN: 9781118554661

Category: Medical

Page: 360

View: 607

A new book in the acclaimed Nutrition Society Textbook Series, Nutrition Research Methodologies addresses the rapidly advancing field of nutrition research. It covers the diverse methodologies required for robust nutritional research to ensure thorough understanding of key concepts, both for students at undergraduate and postgraduate levels and for scientists working in nutrition research. Combining theory with practical application, Nutrition Research Methodologies addresses both traditional research methods and new technologies, and focuses on a range of complex topics, including energy compensation, nutrient-gene interactions and metabolic adaptation. It also considers statistical issues as well as application of data to policy development. Provides the reader with the required scientific basics of nutrition research in the context of a systems and health approach Written specifically to meet the needs of individuals involved in nutrition research Combines the viewpoints of world-leading nutrition experts from academia and research with practical applications Accompanied by a companion website with a range of self-assessment material (www.wiley.com/go/lovegrove/nutritionresearch)
Categories: Medical

Populations and Genetics

Populations and Genetics

These companies are the commercial biobanks . Here “ biobank ” refers to an
entity engaged in the solicitation , collection , and storage of human biological
materials for purposes that include dissemination for research . Human tissue
may be ...

Author: Bartha Maria Knoppers

Publisher: Martinus Nijhoff Publishers

ISBN: 9004136789

Category: Political Science

Page: 648

View: 226

Thirty-five papers from the third International DNA Sampling Conference, held in Montreal in September 2002, provide a critical discussion of the socio-ethical and legal issues surrounding DNA sampling in communities and populations around the globe. Contributors address topics related to biobanks and databases; community engagement; confidentialit.
Categories: Political Science

New Challenges for Biobanks

New Challenges for Biobanks

those of the old types of research biobanks and entail an evolution in the legal
consequences . More concretely , the rights to ... Human tissue research , with
particular reference to DNA banking . In Health Law , Human Rights and the ...

Author: Kris Dierickx

Publisher: Intersentia Uitgevers N V

ISBN: STANFORD:36105134516223

Category: Law

Page: 277

View: 769

The book is a collection of papers presented during an international conference, held in Leuven May 18-20, 2009, organized by the Centre for Biomedical Ethics and Law of the Catholic University of Leuven and the GeneBanC project.
Categories: Law

Human Genetic Biobanks in Asia

Human Genetic Biobanks in Asia

The database is designed for researchonthe genetic and environmental factors
inthe aetiologyofcommon diseasesin Taiwan. Accordingto thepilot project's ...
Compared with traditionalbiomedical research, biobankprojects ofthis magnitude
have some unprecedented features. Tobegin with,they aim to collect tissue
samples ...

Author: Margaret Sleeboom-Faulkner

Publisher: Routledge

ISBN: 9781135784508

Category: Political Science

Page: 224

View: 677

This volume investigates human genetic biobanking and its regulation in various Asian countries and areas, including Japan, Mainland China, Taiwan, Hong Kong, India and Indonesia.. It sheds light on how cultural, socio-political and economic factors influence the set-up of bioethical regulation for human genetic biobanks and how bioethical sensitivities surrounding biobanks are handled. Apart from placing discourses of trust in an international perspective, the comparative materials presented in this volume also put into perspective the concepts of genetic theft and exploitation, and genetic wealth and trust. This collection contains case studies of biobanking practices in societies with different needs and welfare levels, and provides insights into government strategies towards genetic resources by examining bioethics as practised at home.
Categories: Political Science

Global Morality and Life Science Practices in Asia

Global Morality and Life Science Practices in Asia

The natureoftherelation between medical research and society is changing in
fundamental ways. ... This chapterfocuses,in particular, on the collectionof
medical dataand tissues in biobanks, and itsconsequences fordifferent life
assemblages.

Author: M. Sleeboom-Faulkner

Publisher: Springer

ISBN: 9781137317407

Category: Political Science

Page: 242

View: 646

Empirical studies of life science research and biotechnologies in Asia show how assemblages of life articulate bioethics governance with global moralities and reveal why the global harmonization of bioethical standards is contrived.
Categories: Political Science

Intraoperative Consultation E Book

Intraoperative Consultation E Book

... both for immediate treatment decisions and for purposes of biobanking and
future translational research (Table 21-1). ... The minimal equipment that is
needed within the IOC suite is a small workstation for grossing and room for a
tissue ...

Author: Alberto M Marchevsky

Publisher: Elsevier Health Sciences

ISBN: 9780323322997

Category: Medical

Page: 384

View: 992

This new volume in the Foundations in Diagnostic Pathology Series is a highly practical and easy-to-use medical reference book for effectively approaching intraoperative consultations. Ideal for practicing pathologists and their surgical colleagues, it describes the most efficient way to handle specimens, how to focus on the differential diagnosis, and the best methods for reporting findings. Take an integrated approach to intraoperative consultation with chapters that have been coauthored by both pathologists and surgeons. Grasp today's most up-to-date information for the pathologist and surgical team with a templated format that includes techniques of specimen collection, differential diagnosis, additional ancillary studies, terminology, and proper reporting. Effectively perform frozen sections with help from high-quality color illustrations, photomicrographs, and gross photography. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.
Categories: Medical