An Introductory Course in Computational Neuroscience

Author: Paul Miller

Publisher: MIT Press

ISBN: 0262038250

Category: Science

Page: 408

View: 9078

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A textbook for students with limited background in mathematics and computer coding, emphasizing computer tutorials that guide readers in producing models of neural behavior. This introductory text teaches students to understand, simulate, and analyze the complex behaviors of individual neurons and brain circuits. It is built around computer tutorials that guide students in producing models of neural behavior, with the associated Matlab code freely available online. From these models students learn how individual neurons function and how, when connected, neurons cooperate in a circuit. The book demonstrates through simulated models how oscillations, multistability, post-stimulus rebounds, and chaos can arise within either single neurons or circuits, and it explores their roles in the brain. The book first presents essential background in neuroscience, physics, mathematics, and Matlab, with explanations illustrated by many example problems. Subsequent chapters cover the neuron and spike production; single spike trains and the underlying cognitive processes; conductance-based models; the simulation of synaptic connections; firing-rate models of large-scale circuit operation; dynamical systems and their components; synaptic plasticity; and techniques for analysis of neuron population datasets, including principal components analysis, hidden Markov modeling, and Bayesian decoding. Accessible to undergraduates in life sciences with limited background in mathematics and computer coding, the book can be used in a “flipped” or “inverted” teaching approach, with class time devoted to hands-on work on the computer tutorials. It can also be a resource for graduate students in the life sciences who wish to gain computing skills and a deeper knowledge of neural function and neural circuits.
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Computational Neuroscience

A First Course

Author: Hanspeter A Mallot

Publisher: Springer Science & Business Media

ISBN: 3319008617

Category: Computers

Page: 135

View: 2929

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Computational Neuroscience - A First Course provides an essential introduction to computational neuroscience and equips readers with a fundamental understanding of modeling the nervous system at the membrane, cellular, and network level. The book, which grew out of a lecture series held regularly for more than ten years to graduate students in neuroscience with backgrounds in biology, psychology and medicine, takes its readers on a journey through three fundamental domains of computational neuroscience: membrane biophysics, systems theory and artificial neural networks. The required mathematical concepts are kept as intuitive and simple as possible throughout the book, making it fully accessible to readers who are less familiar with mathematics. Overall, Computational Neuroscience - A First Course represents an essential reference guide for all neuroscientists who use computational methods in their daily work, as well as for any theoretical scientist approaching the field of computational neuroscience.
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Computational Neuroscience and Cognitive Modelling

A Student's Introduction to Methods and Procedures

Author: Britt Anderson

Publisher: SAGE

ISBN: 1446297373

Category: Psychology

Page: 240

View: 6011

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"For the neuroscientist or psychologist who cringes at the sight of mathematical formulae and whose eyes glaze over at terms like differential equations, linear algebra, vectors, matrices, Bayes’ rule, and Boolean logic, this book just might be the therapy needed." - Anjan Chatterjee, Professor of Neurology, University of Pennsylvania "Anderson provides a gentle introduction to computational aspects of psychological science, managing to respect the reader’s intelligence while also being completely unintimidating. Using carefully-selected computational demonstrations, he guides students through a wide array of important approaches and tools, with little in the way of prerequisites...I recommend it with enthusiasm." - Asohan Amarasingham, The City University of New York This unique, self-contained and accessible textbook provides an introduction to computational modelling neuroscience accessible to readers with little or no background in computing or mathematics. Organized into thematic sections, the book spans from modelling integrate and firing neurons to playing the game Rock, Paper, Scissors in ACT-R. This non-technical guide shows how basic knowledge and modern computers can be combined for interesting simulations, progressing from early exercises utilizing spreadsheets, to simple programs in Python. Key Features include: Interleaved chapters that show how traditional computing constructs are simply disguised versions of the spread sheet methods. Mathematical facts and notation needed to understand the modelling methods are presented at their most basic and are interleaved with biographical and historical notes for contex. Numerous worked examples to demonstrate the themes and procedures of cognitive modelling. An excellent text for postgraduate students taking courses in research methods, computational neuroscience, computational modelling, cognitive science and neuroscience. It will be especially valuable to psychology students.
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From Neuron to Cognition Via Computational Neuroscience

Author: Michael A. Arbib,James J. Bonaiuto

Publisher: MIT Press

ISBN: 0262034964

Category: Computers

Page: 808

View: 742

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A comprehensive, integrated, and accessible textbook presenting core neuroscientific topics from a computational perspective, tracing a path from cells and circuits to behavior and cognition.
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Fundamentals of Computational Neuroscience

Author: Thomas Trappenberg

Publisher: Oxford University Press

ISBN: 0199568413

Category: Mathematics

Page: 390

View: 5530

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The new edition of Fundamentals of Computational Neuroscience build on the success and strengths of the first edition. It introduces the theoretical foundations of neuroscience with a focus on the nature of information processing in the brain. The book covers the introduction and motivation of simplified models of neurons that are suitable for exploring information processing in large brain-like networks. Additionally, it introduces several fundamental networkarchitectures and discusses their relevance for information processing in the brain, giving some examples of models of higher-order cognitive functions to demonstrate the advanced insight that can begained with such studies.
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Introduction to Dynamic Modeling of Neuro-Sensory Systems

Author: Robert B. Northrop

Publisher: CRC Press

ISBN: 142004172X

Category: Medical

Page: 488

View: 6861

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Although neural modeling has a long history, most of the texts available on the subject are quite limited in scope, dealing primarily with the simulation of large-scale biological neural networks applicable to describing brain function. Introduction to Dynamic Modeling of Neuro-Sensory Systems presents the mathematical tools and methods that can describe and predict the dynamic behavior of single neurons, small assemblies of neurons devoted to a single tasks, as well as larger sensory arrays and their underlying neuropile. Focusing on small and medium-sized biological neural networks, the author pays particular attention to visual feature extraction, especially the compound eye visual system and the vertebrate retina. For computational efficiency, the treatment avoids molecular details of neuron function and uses the locus approach for medium-scale modeling of arrays. Rather than requiring readers to learn a dedicated simulation program, the author uses the general, nonlinear ordinary differential equation solver Simnonä for all examples and exercises. There is both art and science in setting up a computational model that can be validated from existing neurophysiological data. With clear prose, more than 200 figures and photographs, and unique focus, Introduction to Dynamic Modeling of Neuro-Sensory Systems develops the science, nurtures the art, and builds the foundation for more advanced work in neuroscience and the rapidly emerging field of neuroengineering.
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An Introduction to Modeling Neuronal Dynamics

Author: Christoph Börgers

Publisher: Springer

ISBN: 3319511718

Category: Mathematics

Page: 457

View: 5569

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This book is intended as a text for a one-semester course on Mathematical and Computational Neuroscience for upper-level undergraduate and beginning graduate students of mathematics, the natural sciences, engineering, or computer science. An undergraduate introduction to differential equations is more than enough mathematical background. Only a slim, high school-level background in physics is assumed, and none in biology. Topics include models of individual nerve cells and their dynamics, models of networks of neurons coupled by synapses and gap junctions, origins and functions of population rhythms in neuronal networks, and models of synaptic plasticity. An extensive online collection of Matlab programs generating the figures accompanies the book.
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MATLAB for Neuroscientists

An Introduction to Scientific Computing in MATLAB

Author: N.A

Publisher: Academic Press

ISBN: 9780123745514

Category: Computers

Page: 384

View: 8975

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Matlab is the accepted standard for scientific computing, used globally in virtually all Neuroscience and Cognitive Psychology laboratories. For instance, SPM, the most used software for the analysis and manipulation of fMRI images in research and clinical practice is fully programmed in matlab, and its use of the possibility to allow for sophisticated software modules to be freely added to the software has established it as the by far dominant software in the field. Many universities now offer, or are beginning to offer matlab introductory courses in their neuroscience and psychology programs. Nevertheless, so far there hasn't been a textbook specific to this market, and the use of the plethora of existing engineering focused Matlab textbooks is notoriously difficult for teaching the package in those environments. This is the first comprehensive teaching resource and textbook for the teaching of Matlab in the Neurosciences and in Psychology. Matlab is unique in that it can be used to learn the entire empirical and experimental process, including stimulus generation, experimental control, data collection, data analysis and modeling. Thus a wide variety of computational problems can be addressed in a single programming environment. The idea is to empower advanced undergraduates and beginning graduate students by allowing them to design and implement their own analytical tools. As students advance in their research careers, they will have achieved the fluency required to understand and adapt more specialized tools as opposed to treating them as "black boxes". Virtually all computational approaches in the book are covered by using genuine experimental data that are either collected as part of the lab project or were collected in the labs of the authors, providing the casual student with the look and feel of real data. In some rare cases, published data from classical papers are used to illustrate important concepts, giving students a computational understanding of critically important research. The ability to effectively use computers in research is necessary in an academic environment that is increasingly focused on quantitative issues. Matlab represents an ideal language of scientific computing. It is based on powerful linear algebra structures which lend themselves to empirical problems on the one hand, while at the same time allowing the student to make rapid problem-oriented progress (particularly in terms of visualization of data points) without having to lose focus by worrying too much about memory allocation and other "plumbing" minutiae as would be required in other, more low-level programming languages such as C or C++. Currently, there are several books that provide introductions to Matlab that are either too generic and fundamental or too irrelevant for neuroscientists and cognitive psychologists who typically face a very circumscribed range of problems in data collection, data analysis and signal processing. Some non-book tutorials and primers that are in use in the community are typically out of date. Matlab versions are usually not backwards compatible. Many commands and functions used in older tutorials and primers, such as "flops" won't work in current versions of Matlab, necessitating a book that is timely and up-to-date. The complete lack of a relevant resource in this area, combined with a clearly felt need for such a text provided the primary and initial impetus for this project. The authors provide such a dearly needed resource adapting and pooling materials that developed for and used in highly rated courses involving the use of Matlab in Neuroscience at the University of Chicago.
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MATLAB for Neuroscientists

An Introduction to Scientific Computing in MATLAB

Author: Pascal Wallisch,Michael E. Lusignan,Marc D. Benayoun,Tanya I. Baker,Adam Seth Dickey,Nicholas G. Hatsopoulos

Publisher: Academic Press

ISBN: 9780080923284

Category: Medical

Page: 400

View: 888

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This is the first comprehensive teaching resource and textbook for the teaching of MATLAB in the Neurosciences and in Psychology. MATLAB is unique in that it can be used to learn the entire empirical and experimental process, including stimulus generation, experimental control, data collection, data analysis and modeling. Thus a wide variety of computational problems can be addressed in a single programming environment. The idea is to empower advanced undergraduates and beginning graduate students by allowing them to design and implement their own analytical tools. As students advance in their research careers, they will have achieved the fluency required to understand and adapt more specialized tools as opposed to treating them as "black boxes". Virtually all computational approaches in the book are covered by using genuine experimental data that are either collected as part of the lab project or were collected in the labs of the authors, providing the casual student with the look and feel of real data. In some cases, published data from classical papers are used to illustrate important concepts, giving students a computational understanding of critically important research. The first comprehensive textbook on MATLAB with a focus for its application in neuroscience Problem based educational approach with many examples from neuroscience and cognitive psychology using real data Authors are award-winning educators with strong teaching experience
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Biophysics of Computation

Information Processing in Single Neurons

Author: Christof Koch

Publisher: Oxford University Press

ISBN: 0195181999

Category: Medical

Page: 562

View: 7150

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Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.
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