Aliphatic Metabolites

Aliphatic Metabolites

12 2-Methoxytetradecanoic acid Type: Unbranched saturated aliphatic compounds. C15 Source: Sponge Callyspongia fallax (Caribbean Sea). Pharm: Antifungal. Ref: N. M. Carballeira, et al, JNP, 2001, 64, 620 H30 O3 O 9 HO O 13 Methyl ...

Author: Jiaju Zhou

Publisher: Walter de Gruyter GmbH & Co KG

ISBN: 9783110655797

Category: Science

Page: 379

View: 250

This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms. The diversity of structures, biological resources and pharmacological activities are discussed in detail. Molecular structural classification system with 264 structural types are developed. The 6th volume illustrates the molecular formula and structures of aliphatic metabolites.
Categories: Science

Aliphatic Metabolites

Aliphatic Metabolites

This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms.

Author: Jiaju Zhou

Publisher: Walter de Gruyter GmbH & Co KG

ISBN: 9783110654141

Category: Science

Page: 379

View: 148

This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms. The diversity of structures, biological resources and pharmacological activities are discussed in detail. Molecular structural classification system with 264 structural types are developed. The 6th volume illustrates the molecular formula and structures of aliphatic metabolites.
Categories: Science

Xenobiotica

Xenobiotica

Doxylamine aliphatic and pyridine di-A'-oxide was not present, similar to that found in rat and monkey. The urine extracts were then treated ... These metabolites have been previously reported for humans (Gielsdorf and Schubert 1981).

Author:

Publisher:

ISBN: NWU:35558001346630

Category: Chemicals

Page:

View: 674

Categories: Chemicals

Handbook of Mammalian Metabolism of Plant Compounds 1991

Handbook of Mammalian Metabolism of Plant Compounds  1991

Most of the data on the metabolic fate of aliphatic aldehydes deals with the simpler members of the group, formaldehyde and acetaldehyde. This results from the long-standing interest in the toxicity of the former compound, a metabolite ...

Author: Ronald R. Scheline

Publisher: CRC Press

ISBN: 9781351362931

Category: Nature

Page: 522

View: 183

Handbook of Mammalian Metabolism of Plant Compounds provides an extensive survey of how mammals metabolize compounds found in higher plants. Information about these compounds is important to researchers in pharmacology, toxicology, medical and natural products chemistry, and food sciences. Although there is plenty of literature about mammalian metabolism of plant compounds, it is scattered, and summaries of specific plant compounds are often difficult to obtain. This book contains 11 chapters discussing the metabolic fate of individual plant compounds grouped according to chemical class. It also features structural formulas of the compounds and their metabolites, including probable pathways of metabolism. This book provides a convenient single-volume reference source that will benefit all researchers requiring this type of information.
Categories: Nature

Toxicology of the Kidney

Toxicology of the Kidney

The kidneys contain a wide variety of enzymes capable of catalyzing the metabolism of aliphatic halogenated hydrocarbons to chemically reactive metabolites ( 67 , 69-75 ) . Reactive metabolites with slightly longer half - lives may also ...

Author: Jerry B. Hook

Publisher: CRC Press

ISBN: 0881678856

Category: Medical

Page: 588

View: 867

This second edition provides a synthesis of recent research on the mechanisms of chemically-induced kidney injury. The text includes a review of current concepts of clinical nephrotoxicity and renal failure, and mechanisms of specific classes of nephrotoxic drugs and environmental chemicals.
Categories: Medical

Environmental Protection Research Catalog Indexes

Environmental Protection Research Catalog  Indexes

Bos ; Domestic Animals ; Metabolites From Pesticides ; Pesticide Action on Animals ; Pesticide Residues in Feeds ; Residues in Foods ; ... 4.0850 METABOLISM OF CARBAMATE INSECTICIDES ... Aliphatic Carbamates ; Animal Resistance ...

Author: Smithsonian Science Information Exchange

Publisher:

ISBN: OSU:32435027850288

Category: Environmental protection

Page:

View: 921

Categories: Environmental protection

LC NMR

LC NMR

FIGURE 9.12 NMR spectra of compound B and its metabolites B1 and B2. (A) Aliphatic portion of the 1H spectrum of compound B. (B) Aliphatic portion of the 1H spectrum of metabolite B2. (C) Aliphatic portion of the 1H spectrum of ...

Author: Nina C. Gonnella

Publisher: CRC Press

ISBN: 9781351023726

Category: Medical

Page: 314

View: 148

The isolation and structural characterization of substances present at very low concentrations, as is necessary to satisfy regulatory requirements for pharmaceutical drug degradants and impurities, can present scientific challenges. The coupling of HPLC with NMR spectroscopy has been at the forefront of cutting-edge technologies to address these issues. LC-NMR: Expanding the Limits of Structure Elucidation presents a comprehensive overview of key concepts in HPLC and NMR that are required to achieve definitive structure elucidation with very low levels of analytes. Because skill sets from both of these highly established disciplines are involved in LC-NMR, the author provides introductory background to facilitate readers’ proficiency in both areas, including an entire chapter on NMR theory. The much-anticipated second edition provides guidance in setting up LC-NMR systems, discussion of LC methods that are compatible with NMR, and an update on recent hardware and software advances for system performance, such as improvements in magnet design, probe technology, and solvent suppression techniques that enable unprecedented mass sensitivity in NMR. This edition features methods to quantify concentration and assess purity of isolated metabolites on the micro scale and incorporates computational approaches to accelerate the structure elucidation process. The author also includes implementation and application of qNMR and automated and practical use of computational chemistry combined with QM and DFT to predict highly accurate NMR chemical shifts. The text focuses on current developments in chromatographic-NMR integration, with particular emphasis on utility in the pharmaceutical industry. Applications include trace analysis, analysis of mixtures, and structural characterization of degradation products, impurities, metabolites, peptides, and more. The text discusses novel uses and emerging technologies that challenge detection limits as well future directions for this important technique. This book is a practical primary resource for NMR structure determination—including theory and application—that guides the reader through the steps required for isolation and NMR structure elucidation on the micro scale.
Categories: Medical

Industrially Important Fungi for Sustainable Development

Industrially Important Fungi for Sustainable Development

Endophytes metabolites could be grouped according to their chemistry into; xanthones, isocoumarins, quinones alkaloids, steroids, terpenoids, flavonoids, glycosides, phenyl propanoids, lignans, aliphatic metabolites, lactones, etc.

Author: Ahmed M. Abdel-Azeem

Publisher: Springer Nature

ISBN: 9783030856038

Category: Fungi

Page: 823

View: 345

Fungi are an essential, fascinating and biotechnologically useful group of organisms with an incredible biotechnological potential for industrial exploitation. Knowledge of the world's fungal diversity and its use is still incomplete and fragmented. There are many opportunities to accelerate the process of filling knowledge gaps in these areas. The worldwide interest of the current era is to increase the tendency to use natural substances instead of synthetic ones. The increasing urge in society for natural ingredients has compelled biotechnologists to explore novel bioresources which can be exploited in industrial sector. Fungi, due to their unique attributes and broad range of their biological activities hold great promises for their application in biotechnology and industry. Fungi are an efficient source of antioxidants, enzymes, pigments, and many other secondary metabolites. The large scale production of fungal pigments and their utility provides natural coloration without creating harmful effects on entering the environment, a safer alternative use to synthetic colorants. The fungal enzymes can be exploited in wide range of industries such as food, detergent, paper, and also for removal toxic waste. This book will serve as valuable source of information as well as will provide new directions to researchers to conduct novel research in field of mycology. Volume 2 of "Industrially Important Fungi for Sustainable Development" provides an overview to understanding bioprospecting of fungal biomolecules and their industrial application for future sustainability. It encompasses current advanced knowledge of fungal communities and their potential biotechnological applications in industry and allied sectors. The book will be useful to scientists, researchers, and students of microbiology, biotechnology, agriculture, molecular biology, and environmental biology.
Categories: Fungi

Structural Correlates of Carcinogenesis and Mutagenesis

Structural Correlates of Carcinogenesis and Mutagenesis

It is hard to predict that any one group of enzymes or substrates will form an ultimate metabolite . We need more overall metabolism studies ... However , the reactive metabolites are either aliphatic compounds , or benzylic ones .

Author: Irvin M. Asher

Publisher:

ISBN: IND:30000105904571

Category: Carcinogenicity testing

Page: 252

View: 661

Categories: Carcinogenicity testing

Annual Plant Reviews Biology of Plant Metabolomics

Annual Plant Reviews  Biology of Plant Metabolomics

... sugar/ aliphatic metabolites and amino acids as inferred from closer connection and more frequent relations between these two groups in mycorrhizal root metabolism. One major drawback of this type of metabolite profiling studies is, ...

Author: Robert D. Hall

Publisher: John Wiley & Sons

ISBN: 9781444339949

Category: Science

Page: 448

View: 274

Biology of Plant Metabolomics is an exciting new volume in Wiley-Blackwell's highly successful Annual Plant Reviews series. Concentrating on the biology and biological relevance of plant metabolomics, each chapter, written by internationally-acknowledged experts in the field from at least two different research groups, combines a review of the existing biological results with an extended assessment of possible future developments and the impact that these will have on the type of research needed for the future. Following a general introduction, this exciting volume includes details of metabolomics of model species including Arabidopsis and tomato. Further chapters provide in-depth coverage of abiotic stress, data integration, systems biology, genetics, genomics, chemometrics and biostatisitcs. Applications of plant metabolomics in food science, plant ecology and physiology are also comprehensively covered. Biology of Plant Metabolomics provides cutting edge reviews of many major aspects of this new and exciting subject. It is an essential purchase for plant scientists, plant geneticists and physiologists. All libraries in universities and research establishments where biological sciences are studied and taught should have a copy of this Annual Plant Reviews volume on their shelves.
Categories: Science