Advances in Linear Free Energy Relationships

Advances in Linear Free Energy Relationships

That interest continues to be an active one and, to judge merely by the extensive biblio graphies contained in the present volume, it is widely shared.

Author: N. Chapman

Publisher: Springer

ISBN: STANFORD:36105031888428

Category: Science

Page: 508

View: 551

Louis P. Hammett Mitchill Professor Emeritus of Chemistry, Columbia University My interest in linear free energy relationships began when, just out of graduate school, I read in 1924 the article by Bmnsted and Pedersen which for the first time reported the existence of such a relationship. That interest continues to be an active one and, to judge merely by the extensive biblio graphies contained in the present volume, it is widely shared. To my mind a particularly happy aspect of the existence of linear free energy relationships has been the proof it supplies that one need not suppose that the behavior of nature is hopelessly complicated merely because one cannot find a theoretical reason for supposing it to be otherwise. The effect of a substituent in an organic molecule on rate or equilibrium of reaction involves a fourfold difference between relatively large quantities, a situation which always makes for difficult theory. Yet systematic organic chemistry could hardly have existed were it not true that like changes in structure lead to like changes in reactivity. Linear free energy relationships constitute the quantitative specialisation of this fundamental principle, and they stand indeed more in the office of teacher to theory than in that of learner from it.
Categories: Science

Advances in Linear Free Energy Relationships

Advances in Linear Free Energy Relationships

Chapter 8 Linear Free Energy Relationships in Enzymology Jack F. Kirsch Department of Biochemistry, University of California, Berkeley, California 94720 8.1. INTRODUCTION - • - 8.1.1. Kinetic Models for Enzyme Action s • • • • 8.1.2.

Author: N. Chapman

Publisher: Springer Science & Business Media

ISBN: 9781461586609

Category: Science

Page: 486

View: 547

Louis P. Hammett Mitchill Professor Emeritus of Chemistry, Columbia University My interest in linear free energy relationships began when, just out of graduate school, I read in 1924 the article by Bmnsted and Pedersen which for the first time reported the existence of such a relationship. That interest continues to be an active one and, to judge merely by the extensive biblio graphies contained in the present volume, it is widely shared. To my mind a particularly happy aspect of the existence of linear free energy relationships has been the proof it supplies that one need not suppose that the behavior of nature is hopelessly complicated merely because one cannot find a theoretical reason for supposing it to be otherwise. The effect of a substituent in an organic molecule on rate or equilibrium of reaction involves a fourfold difference between relatively large quantities, a situation which always makes for difficult theory. Yet systematic organic chemistry could hardly have existed were it not true that like changes in structure lead to like changes in reactivity. Linear free energy relationships constitute the quantitative specialisation of this fundamental principle, and they stand indeed more in the office of teacher to theory than in that of learner from it.
Categories: Science

Chemical Kinetics and Process Dynamics in Aquatic Systems

Chemical Kinetics and Process Dynamics in Aquatic Systems

Chipperfield, J.R., in Advances in Linear Free Energy Relationships, N.B. Chapman and J. Shorter (Eds.), Plenum Press, London, 1972, pp. 321–368; Langmuir, D., in Chemical Models, E.A. Jenne (Ed.), ACS Symp. Ser. 93, Am. Chem.

Author: PatrickL. Brezonik

Publisher: Routledge

ISBN: 9781351461504

Category: Science

Page: 540

View: 709

Chemical Kinetics and Process Dynamics in Aquatic Systems is devoted to chemical reactions and biogeochemical processes in aquatic systems. The book provides a thorough analysis of the principles, mathematics, and analytical tools used in chemical, microbial, and reactor kinetics. It also presents a comprehensive, up-to-date description of the kinetics of important chemical processes in aquatic environments. Aquatic photochemistry and correlation methods (e.g., LFERs and QSARs) to predict process rates are covered. Numerous examples are included, and each chapter has a detailed bibliography and problems sets. The book will be an excellent text/reference for professionals and students in such fields as aquatic chemistry, limnology, aqueous geochemistry, microbial ecology, marine science, environmental and water resources engineering, and geochemistry.
Categories: Science

Free Energy Relationships in Organic and Bio Organic Chemistry

Free Energy Relationships in Organic and Bio Organic Chemistry

Advances in Linear Free Energy Relationships, Plenum Press, New York, 1972. J.O. Edwards and R.G. Pearson, The Factors Determining Nucleophilic Reactivities, J. Am. Chem. Soc., 1962, 84, 16. I. A. Koppel and V.A. Palm, The Influence of ...

Author: Andrew Williams

Publisher: Royal Society of Chemistry

ISBN: 9781788018302

Category: Science

Page: 290

View: 106

Introducing the application of free energy correlations to elucidating the mechanisms of organic and bio-organic reactions, this book provides a new and illuminating way of approaching a potentially complex topic. The idea of how free energy correlations derive from polar substituent change is introduced, and common pitfalls encountered in the application of free energy relationships are described, along with the use of these anomalies in mechanistic studies. The concept of effective charge is described in detail, with examples of its application. Throughout, worked answers are provided for the problems posed. Databases of parameters, an extensive bibliography and comprehensive lists of further reading are also included. The text provides an invaluable source of information to senior undergraduates, postgraduates and to industrial researchers with an interest in mechanistic studies. It is the first such book in more than thirty years.
Categories: Science

Advanced Organic Chemistry

Advanced Organic Chemistry

Linear Free-Energy Relationships for Substituent Effects 3.6.1. Numerical Expression of Linear Free-Energy Relationships Many important relationships between substituent groups and chemical properties have been developed.

Author: Francis A. Carey

Publisher: Springer Science & Business Media

ISBN: 9780387448978

Category: Science

Page: 1213

View: 802

The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part A covers fundamental structural topics and basic mechanistic types. It can stand-alone; together, with Part B: Reaction and Synthesis, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for study of structure, reaction and selectivity for students and exercise solutions for instructors.
Categories: Science

Solvents and Solvent Effects in Organic Chemistry

Solvents and Solvent Effects in Organic Chemistry

Advances in Linear Free Energy Relationships, Plenum Press, London, New York, 1972, Chapter 5, p. 203¤. [7] J. A. Hirsch: Concepts in Theoretical Organic Chemistry, Allyn and Bacon, Boston, 1974, Chapter 9, p. 207¤.

Author: Christian Reichardt

Publisher: John Wiley & Sons

ISBN: 9783527605675

Category: Science

Page: 653

View: 897

In most cases, every chemist must deal with solvent effects, whether voluntarily or otherwise. Since its publication, this has been the standard reference on all topics related to solvents and solvent effects in organic chemistry. Christian Reichardt provides reliable information on the subject, allowing chemists to understand and effectively use these phenomena. 3rd updated and enlarged edition of a classic 35% more contents excellent, proven concept includes current developments, such as ionic liquids indispensable in research and industry From the reviews of the second edition: "...This is an immensely useful book, and the source that I would turn to first when seeking virtually any information about solvent effects." —Organometallics
Categories: Science

Progress in Molecular and Subcellular Biology

Progress in Molecular and Subcellular Biology

SHORTER, J. : The separation of polar, steric, and resonance effects by the use of linear free energy relationships. In: Advances in Linear Free Energy Relationships (Eds. N. B. CHAPMAN, J. SHORTER), p. 71. London: Plenum Press 1972.

Author:

Publisher: Springer Science & Business Media

ISBN: 9783642666261

Category: Science

Page: 178

View: 221

Categories: Science

Advanced Physical Chemistry

Advanced Physical Chemistry

Thus there exists a straight line or linear relationship between free energy terms for these two different reaction series . These types of straight line Hammett plots in Fig . 1 are termed as linear free energy relationships .

Author: Mehra Harish C

Publisher: Krishna Prakashan Media

ISBN: 8187224096

Category:

Page: 1484

View: 428

Categories:

CRC Handbook of Solubility Parameters and Other Cohesion Parameters

CRC Handbook of Solubility Parameters and Other Cohesion Parameters

Koppel, I. A. and Palm, V. A., The influence of the solvent on organic reactivity, in Advances in Linear Free Energy Relationships, Chapman, N. B. and Shorter, J. Eds., Plenum Press, London, 1972, chap. 5. 31. Kosower, E. M., The effect ...

Author: Allan F.M. Barton

Publisher: Routledge

ISBN: 9781351457187

Category: Science

Page: 1335

View: 204

The CRC Handbook of Solubility Parameters and Other Cohesion Parameters, Second Edition, which includes 17 new sections and 40 new data tables, incorporates information from a vast amount of material published over the last ten years. The volume is based on a bibliography of 2,900 reports, including 1,200 new citations. The detailed, careful construction of the handbook develops the concept of solubility parameters from empirical, thermodynamic, and molecular points of view and demonstrates their application to liquid, gas, solid, and polymer systems.
Categories: Science

March s Advanced Organic Chemistry

March s Advanced Organic Chemistry

... Chapman, N.B.; Shorter, J. Correlation Analysis in Chemistry: Recent Advances, Plenum, NY, 1978, Advances in Linear Free Energy Relationships, Plenum, NY, 1972; Wells, P.R. Linear Free Energy Relationships, Academic Press, NY, 1968.

Author: Michael B. Smith

Publisher: John Wiley & Sons

ISBN: 9780470084946

Category: Science

Page: 2380

View: 141

The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: More than 25,000 references to the literature to facilitate further research Revised mechanisms, where required, that explain concepts in clear modern terms Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries A revised Appendix B to facilitate correlating chapter sections with synthetic transformations
Categories: Science