A Crack in Creation

Gene Editing and the Unthinkable Power to Control Evolution

Author: Jennifer A. Doudna,Samuel H. Sternberg

Publisher: Houghton Mifflin Harcourt

ISBN: 0544716965

Category: Science

Page: 320

View: 3950

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Finalist for the Los Angeles Times Book Prize “The future is in our hands as never before, and this book explains the stakes like no other.” — George Lucas “Required reading for every concerned citizen.” — New York Review of Books Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences—to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Sam Sternberg, Doudna shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. “An invaluable account . . . We owe Doudna several times over.” — Guardian
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Summary & Study Guide - A Crack in Creation

Gene Editing and the Unthinkable Power to Control Evolution

Author: Lee Tang

Publisher: LMT Press

ISBN: 0995943168

Category: Business & Economics

Page: 88

View: 4244

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Power and Peril of Gene Editing CRISPR/Cas9 Technology The must-read summary of “A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution” by Jennifer A. Doudna and Samuel H. Sternberg. This complete summary of Jennifer Doudna and Samuel Sternberg’s book tells the story of CRISPR and “gene-editing.” CRISPR is a cutting-edge gene-editing technology that mimics what happens naturally in bacteria. It enables scientists to “play god” with plant or animal DNA, with unlimited power and peril. The technology of gene editing is the most important advance in our era. The possibility of forever altering the genetic composition of humankind is frightening. Yet we can’t overlook the opportunities that may lead to inventions for cures of HIV, debilitating genetic diseases, and cancers, and end food shortages. The book will demystify this exciting area of science and inspire you to seek answers to tough moral and ethical questions on the use of this technology. Read this summary and get involved in the debate on the moral and ethical issues on the use of this technology. This guide includes: * Book Summary—helps you understand the key concepts. * Online Videos—covers the concepts in more depth. Value-added from this guide: * Save time * Understand key concepts * Expand your knowledge
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A Crack in Creation

Gene Editing and the Unthinkable Power to Control Evolution

Author: Jennifer A. Doudna,Samuel H. Sternberg

Publisher: Houghton Mifflin

ISBN: 9780544716940

Category: MEDICAL

Page: 281

View: 7022

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Two Berkeley scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.
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A Crack in Creation

The New Power to Control Evolution

Author: Jennifer A. Doudna,Samuel H. Sternberg

Publisher: Jonathan Cape

ISBN: 9781847923820

Category: CRISPR-cas systems

Page: 304

View: 9217

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Jennifer Doudna, the world-famous scientist behind CRISPR, 'one of the most monumental discoveries in biology' (New York Times), describes its power to reshape the future of all life and warns of its use. A handful of discoveries have changed the course of human history. This book is about the most recent and potentially the most powerful and dangerous of them all. It is an invention that allows us to rewrite the genetic code that shapes and controls all living beings with astonishing accuracy and ease. Thanks to it, the dreams of genetic manipulation have become a stark reality- the power to cure disease and alleviate suffering, to create new sources of food and energy, as well as to re-design any species, including humans, for our own ends. Jennifer Doudna is the co-inventor of this technology, known as CRISPR, and a scientist of worldwide renown. Writing with fellow researcher Samuel Sternberg, here she provides the definitive account of her discovery, explaining how this wondrous invention works and what it is capable of. A Crack In Creationalso asks us to consider what our new-found power means- how do we enjoy its unprecedented benefits while avoiding its equally unprecedented dangers? As Doudna argues, every member of our species is implicated in the answers to these questions. Somehow we must consider and act together. The future of humankind - and of all life on Earth - is at stake. This book is an essential guide to the path that now lies ahead.
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Psychoanalysis of Technoscience

Symbolisation and imagination

Author: Hub Zwart

Publisher: LIT Verlag Münster

ISBN: 3643910509

Category:

Page: 200

View: 5636

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This book presents a psychoanalysis of technoscience. Basic concepts and methods developed by Freud, Jung, Bachelard and Lacan are applied to case histories (palaeoanthropology, classical conditioning, virology). Rather than by disinterested curiosity, technoscience is driven by desire, resistance and the will to control. Moreover, psychoanalysis focusses on primal scenes (Dubois' quest for the missing link, Pavlov's discovery of the conditioned reflex) and opts for triangulation: comparing technoscience to "different scenes" provided by novels, so that Dubois's work is compared to missing link novels by Verne and London and Pavlov's experiments with Skinner's Walden Two, while virology is studied through the lens of viral fiction.
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Genome Editing and Engineering

From TALENs, ZFNs and CRISPRs to Molecular Surgery

Author: Krishnarao Appasani

Publisher: Cambridge University Press

ISBN: 1107170370

Category: Science

Page: 586

View: 9246

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A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment.
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Falter

Has the Human Game Begun to Play Itself Out?

Author: Bill McKibben

Publisher: Henry Holt and Company

ISBN: 1250178274

Category: Nature

Page: 272

View: 9860

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Thirty years ago Bill McKibben offered one of the earliest warnings about climate change. Now he broadens the warning: the entire human game, he suggests, has begun to play itself out. Bill McKibben’s groundbreaking book The End of Nature -- issued in dozens of languages and long regarded as a classic -- was the first book to alert us to global warming. But the danger is broader than that: even as climate change shrinks the space where our civilization can exist, new technologies like artificial intelligence and robotics threaten to bleach away the variety of human experience. Falter tells the story of these converging trends and of the ideological fervor that keeps us from bringing them under control. And then, drawing on McKibben’s experience in building 350.org, the first truly global citizens movement to combat climate change, it offers some possible ways out of the trap. We’re at a bleak moment in human history -- and we’ll either confront that bleakness or watch the civilization our forebears built slip away. Falter is a powerful and sobering call to arms, to save not only our planet but also our humanity.
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Summary & Study Guide - The Alzheimer's Solution

A Breakthrough Program to Prevent and Reverse Cognitive Decline at Every Age

Author: Lee Tang

Publisher: N.A

ISBN: 1988970024

Category: Health & Fitness

Page: 43

View: 5216

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Reduce Risk of Alzheimer’s Disease by 90% Optimize Your Cognitive Function The must-read summary of “The Alzheimer’s Solution: A Breakthrough Program to Prevent and Reverse the Symptoms of Cognitive Decline at Every Age,” by Dean & Ayesha Sherzai, MD. This complete summary of Dean & Ayesha Sherzai’s book explains the biology of Alzheimer’s disease and the five-part program to prevent and reverse cognitive decline. By following this program, ninety percent of us can avoid ever getting Alzheimer’s. The ten percent with strong genetic risk for Alzheimer’s can delay the disease by ten to fifteen years. Those diagnosed with the disease can reverse the symptoms, be cognitively active, and add healthy years to life. This guide includes: • Book Summary—The summary helps you understand the key ideas and recommendations. • Online Videos—On-demand replay of public lectures, and seminars on the topics covered in the chapter. Value-added of this guide: • Save time • Understand key concepts • Expand your knowledge Read this summary and apply the ideas to prevent and reverse the symptoms of this debilitating illness that threaten you and your loved ones.
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Precision Medicine for Investigators, Practitioners and Providers

Author: Joel Faintuch,Salomao Faintuch

Publisher: Academic Press

ISBN: 0128191791

Category: Science

Page: 640

View: 1845

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Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked
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