Synthetic Biology Handbook

Author: Darren N. Nesbeth

Publisher: CRC Press

ISBN: 1466568488

Category: Medical

Page: 318

View: 3796

The Synthetic Biology Handbook explains the major goals of the field of synthetic biology and presents the technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of the current areas of focus in synthetic biology, this handbook: Explores the standardisation of classic molecular bioscience approaches Addresses the societal context and potential impacts of synthetic biology Discusses the use of legacy systems as tools for new product development Examines the design and construction of de novo cells and genetic codes Describes computational methods for designing genes and gene networks Thus, the Synthetic Biology Handbook provides an accurate sense of the scope of synthetic biology today. The handbook also affords readers with an opportunity to scrutinize the underlying science and decide for themselves what aspects of synthetic biology are most valuable to their research and practice.
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Handbook of Computational Molecular Biology

Author: Srinivas Aluru

Publisher: CRC Press

ISBN: 9781420036275

Category: Science

Page: 1104

View: 9938

The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. Computational biology is a young field, but has seen rapid growth and advancement over the past few decades. Surveying the progress made in this multidisciplinary field, the Handbook of Computational Molecular Biology offers comprehensive, systematic coverage of the various techniques and methodologies currently available. Accomplished researcher Srinivas Aluru leads a team of experts from around the world to produce this groundbreaking, authoritative reference. With discussions ranging from fundamental concepts to practical applications, this book details the algorithms necessary to solve novel problems and manage the massive amounts of data housed in biological databases throughout the world. Divided into eight sections for convenient searching, the handbook covers methods and algorithms for sequence alignment, string data structures, sequence assembly and clustering, genome-scale computational methods in comparative genomics, evolutionary and phylogenetic trees, microarrays and gene expression analysis, computational methods in structural biology, and bioinformatics databases and data mining. The Handbook of Computational Molecular Biology is the first resource to integrate coverage of the broad spectrum of topics in computational biology and bioinformatics. It supplies a quick-reference guide for easy implementation and provides a strong foundation for future discoveries in the field.
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Handbook of Biochemistry and Molecular Biology, Fourth Edition

Author: Roger L. Lundblad,Fiona Macdonald

Publisher: CRC Press

ISBN: 1466515155

Category: Medical

Page: 1098

View: 2014

Edited by renowned protein scientist and bestselling author Roger L. Lundblad, with the assistance of Fiona M. Macdonald of CRC Press, this fourth edition of the Handbook of Biochemistry and Molecular Biology represents a dramatic revision — the first in two decades — of one of biochemistry's most referenced works. This edition gathers a wealth of information not easily obtained, including information not found on the web. Offering a molecular perspective not available 20 years ago, it provides physical and chemical data on proteins, nucleic acids, lipids, and carbohydrates. Presented in an organized, concise, and simple-to-use format, this popular reference allows quick access to the most frequently used data. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents. Just a small sampling of the wealth of information found inside the handbook: Buffers and buffer solutions Heat capacities and combustion levels Reagents for the chemical modification of proteins Comprehensive classification system for lipids Biological characteristics of vitamins A huge variety of UV data Recommendations for nomenclature and tables in biochemical thermodynamics Guidelines for NMR measurements for determination of high and low pKa values Viscosity and density tables Chemical and physical properties of various commercial plastics Generic source-based nomenclature for polymers Therapeutic enzymes About the Editors: Roger L. Lundblad, Ph.D. Roger L. Lundblad is a native of San Francisco, California. He received his undergraduate education at Pacific Lutheran University and his PhD degree in biochemistry at the University of Washington. After postdoctoral work in the laboratories of Stanford Moore and William Stein at the Rockefeller University, he joined the faculty of the University of North Carolina at Chapel Hill. He joined the Hyland Division of Baxter Healthcare in 1990. Currently Dr. Lundblad is an independent consultant and writer in biotechnology in Chapel Hill, North Carolina. He is an adjunct Professor of Pathology at the University of North Carolina at Chapel Hill and Editor-in-Chief of the Internet Journal of Genomics and Proteomics. Fiona M. Macdonald, Ph.D., F.R.S.C. Fiona M. Macdonald received her BSc in chemistry from Durham University, UK. She obtained her PhD in inorganic biochemistry at Birkbeck College, University of London, studying under Peter Sadler. Having spent most of her career in scientific publishing, she is now at Taylor and Francis and is involved in developing chemical information products.
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Practical Handbook of Biochemistry and Molecular Biology

Author: Gerald D. Fasman

Publisher: CRC Press

ISBN: 9780849337055

Category: Science

Page: 616

View: 9517

Methodologies and databases for biochemistry and molecular biology are included in this easy-to-use laboratory reference. Its logical presentation enables the reader to quickly and conveniently locate the information relevant to his or her needs. Featured are tables containing data on amino acids, proteins, nucleosides, nucleotides, and nucleic acids. Also featured are lipids and physical chemical data. Edited by a leading professional in the field, this compact, yet comprehensive bench manual serves as the definitive reference source for your laboratory.
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Handbook of Biochemistry and Molecular Biology

Author: Roger L. Lundblad,Fiona Macdonald

Publisher: CRC Press

ISBN: 1315314436

Category: Medical

Page: 1001

View: 3633

Edited by renowned protein scientist and bestselling author Roger L. Lundblad, with the assistance of Fiona M. Macdonald of CRC Press, this fifth edition of the Handbook of Biochemistry and Molecular Biology gathers a wealth of information not easily obtained, including information not found on the web. Presented in an organized, concise, and simple-to-use format, this popular reference allows quick access to the most frequently used data. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents. An entirely new section on Chemical Biology and Drug Design gathers data on amino acid antagonists, click chemistry, plus glossaries for computational drug design and medicinal chemistry. Each table is exhaustively referenced, giving the user a quick entry point into the primary literature. New tables for this edition: Chromatographic methods and solvents Protein spectroscopy Partial volumes of amino acids Matrix Metalloproteinases Gene Editing Click Chemistry
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Handbook of Chemical and Biological Sensors

Author: R.F Taylor,Jerome S. Schultz

Publisher: CRC Press

ISBN: 9781420050486

Category: Science

Page: 604

View: 8253

The Handbook of Chemical and Biological Sensors focuses on the development of sensors to recognize substances rather than physical quantities. This fully inclusive book examines devices that use a biological sensing element to detect and measure chemical and biological species as well as those that use a synthetic element to achieve a similar result. A first port of call for anyone with a specific interest, question, or problem relating to this area, this comprehensive source of reference serves as a guide for practicing scientists and as a text for many graduate courses. It presents relevant physics to chemists, chemistry to materials scientists, materials science to electronic engineers, and fabrication technology to all of the above. In addition, the handbook is useful both to newcomers and to experienced researchers who wish to broaden their knowledge of the constituent disciplines of this wide-ranging field.
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Chemical Synthetic Biology

Author: Pier Luigi Luisi,Cristiano Chiarabelli

Publisher: John Wiley & Sons

ISBN: 9781119990307

Category: Science

Page: 392

View: 4629

Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, computational genomics, and bioinformatics.
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Applications of Membrane Computing in Systems and Synthetic Biology

Author: Pierluigi Frisco,Marian Gheorghe,Mario J. Pérez-Jiménez

Publisher: Springer Science & Business Media

ISBN: 3319031910

Category: Computers

Page: 266

View: 4757

Membrane Computing was introduced as a computational paradigm in Natural Computing. The models introduced, called Membrane (or P) Systems, provide a coherent platform to describe and study living cells as computational systems. Membrane Systems have been investigated for their computational aspects and employed to model problems in other fields, like: Computer Science, Linguistics, Biology, Economy, Computer Graphics, Robotics, etc. Their inherent parallelism, heterogeneity and intrinsic versatility allow them to model a broad range of processes and phenomena, being also an efficient means to solve and analyze problems in a novel way. Membrane Computing has been used to model biological systems, becoming with time a thorough modeling paradigm comparable, in its modeling and predicting capabilities, to more established models in this area. This book is the result of the need to collect, in an organic way, different facets of this paradigm. The chapters of this book, together with the web pages accompanying them, present different applications of Membrane Systems to Biology. Deterministic, non-deterministic and stochastic systems paired with different algorithms and methodologies show the full potential of this framework. The book is addressed to researchers interested in applications of discrete biological models and the interplay between Membrane Systems and other approaches to analyze complex systems.
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The Cambridge Handbook of Artificial Intelligence

Author: Keith Frankish,William M. Ramsey

Publisher: Cambridge University Press

ISBN: 0521871425

Category: Computers

Page: 368

View: 3292

An authoritative, up-to-date survey of the state of the art in artificial intelligence, written for non-specialists.
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Handbook of Bioseparations

Author: Satinder Ahuja

Publisher: Elsevier

ISBN: 9780080507798

Category: Technology & Engineering

Page: 722

View: 6869

It is generally recognized that the commercial success of biotechnology products is highly dependent on the successful development and application of high-powered separation and purification methods. In this practical and authoritative handbook, the separation of proteins, nucleic acids, and oligonucleotides from biological matrices is covered from analytical to process scales. Also included in a chapter on the separation of monoclonal antibodies, which have found numerous uses as therapeutic and diagnostic agents. Analytical techniques include an interesting montage of chromatographic methods, capillary electrophoresis, isoelectric focusing, and mass spectrometry. Among separation and purification methods, liquid-liquid distribution, displacement chromatography, expanded bed adsorption, membrane chromatography, and simulated moving bed chromatography are covered at length. Regulatory and economic considerations are addressed, as are plant and process equipment and engineering process control. A chapter on future developments highlights the application of DNA chip arrays as well as evolving methodologies for a large number of drugs that are under development for treatment of cancer, AIDS, rheumatoid arthritis, and Alzheimer's disease. Handbook of Bioseparations serves as an essential reference and guidebook for separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories. Key Features * Covers bioseparations of proteins, nucleic acids, and monoclonal antibodies * Encompasses both analytical and process-scale methods * Elucidates the importance of engineering process control * Details selection of plant and process equipment * Addresses economic considerations * Discusses future developments
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Biomedical Engineering Handbook

Author: Joseph D. Bronzino

Publisher: CRC Press

ISBN: 9780849304620

Category: Medical

Page: 1512

View: 4925

P Winner of the Association of American Publishers Best New Professional/Scholarly Publication - Engineering
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Seeds Handbook

Processing And Storage

Author: Babasaheb B. Desai

Publisher: CRC Press

ISBN: 9780824748005

Category: Science

Page: 800

View: 1435

Revised and expanded throughout, this latest edition of the bestselling Seeds Handbook: Biology, Production, Processing, and Storage includes valuable information on all areas of seed biology, production, and processing. The author, one of the most respected and prolific scientists in the field, identifies current developments in seed testing and certification, storage, transportation, and distribution. Tracking the evolution and advancement of seed industries and technologies, he fully covers the development and supply of high-quality seeds for every key agronomic and horticulture crop. Contains methods to enhance the genetic and physiological characteristics of more than 80 major and minor crops With an abundance of current research and additional figures and illustrations, this edition of the Seeds Handbook offers chapters on modern biotechnological issues such as the production of synthetic seeds, loss-reduction biotechnologies, and new strategies in the seed production industry. It provides in-depth information on burgeoning areas of seed science including tissue culture and cellular totipotency, induction and regeneration protocols, development and maturation, hormone requirements, drying and storage of somatic embryos, protective encapsulation, and crop applications. With an eye to the future, it looks at challenges in the provision and enhancement of seeds for crop plants, practical methods of seed production and micropropagation, genetically modified seeds, and world food security.
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The Nucleic Acid Protocols Handbook

Author: Ralph Rapley

Publisher: Springer Science & Business Media

ISBN: 1592590381

Category: Science

Page: 478

View: 1082

A comprehensive treasury of all the key molecular biology methods-ranging from DNA extraction to gene localization in situ-needed to function effectively in the modern laboratory. Each of the 120 highly successful techniques follows the format of the much acclaimed Methods in Molecular BiologyOao series, providing an introduction to the scientific basis of each technique, a complete listing of all the necessary materials and reagents, and clear step-by-step instruction to permit error-free execution. Included for each technique are notes about pitfalls to avoid, troubleshooting tips, alternate methods, and explanations of the reasons for certain steps-all key elements contributing significantly to success or failure in the lab. The Nucleic Acid Protocols Handbook constitutes today's most comprehensive collection of all the key classic and cutting-edge techniques for the successful isolation, analysis, and manipulation of nucleic acids by both experienced researchers and those new to the field."
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Handbook of Physics in Medicine and Biology

Author: Robert Splinter

Publisher: CRC Press

ISBN: 142007525X

Category: Science

Page: 548

View: 8752

In considering ways that physics has helped advance biology and medicine, what typically comes to mind are the various tools used by researchers and clinicians. We think of the optics put to work in microscopes, endoscopes, and lasers; the advanced diagnostics permitted through magnetic, x-ray, and ultrasound imaging; and even the nanotools, that allow us to tinker with molecules. We build these instruments in accordance with the closest thing to absolute truths we know, the laws of physics, but seldom do we apply those same constants of physics to the study of our own carbon-based beings, such as fluidics applied to the flow of blood, or the laws of motion and energy applied to working muscle. Instead of considering one aspect or the other, Handbook of Physics in Medicine and Biology explores the full gamut of physics’ relationship to biology and medicine in more than 40 chapters, written by experts from the lab to the clinic. The book begins with a basic description of specific biological features and delves into the physics of explicit anatomical structures starting with the cell. Later chapters look at the body's senses, organs, and systems, continuing to explain biological functions in the language of physics. The text then details various analytical modalities such as imaging and diagnostic methods. A final section turns to future perspectives related to tissue engineering, including the biophysics of prostheses and regenerative medicine. The editor’s approach throughout is to address the major healthcare challenges, including tissue engineering and reproductive medicine, as well as development of artificial organs and prosthetic devices. The contents are organized by organ type and biological function, which is given a clear description in terms of electric, mechanical, thermodynamic, and hydrodynamic properties. In addition to the physical descriptions, each chapter discusses principles of related clinical diagnostic methods and technological aspects of therapeutic applications. The final section on regenerative engineering, emphasizes biochemical and physiochemical factors that are important to improving or replacing biological functions. Chapters cover materials used for a broad range of applications associated with the replacement or repair of tissues or entire tissue structures.
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Handbook of Synthetic Substrates

Author: H.C. Hemker

Publisher: Springer Science & Business Media

ISBN: 9400966903

Category: Medical

Page: 192

View: 4017

The need for a handbook on the use of synthetic substrates for assay of proteases of the coagulation and fibrinolytic systems became evident several years ago during the activities of the Subcommittee on Synthetic Substrates of the International Committee on Thrombosis and Haemo stasis (lCTH). Production of such a handbook, which was recommended during discussions of the ICTH at its meeting in London in 1979 was made possible by the generous efforts of Professor HC Hemker with the aid of several contributors with particular interests in the use of synthetic substrates in coagulation and fibrinolysis. As current Chairman and Secretary General of the ICTH we would like to express our sincere thanks to Professor Hemker for producing this handbook and look for ward to seeing the benefits of this tremendous effort reflected in the advancement of our understanding of thrombosis and hemostasis and the transfer of such knowledge into improved diagnosis and treatment of thrombotic and hemorrhagic disorders. Craig M Jackson Professor of Biological Chemistry Washington University School of Medicine, St. Louis, MO Chairman, ICTH Harold R Roberts Professor of Internal Medicine University of North Carolina, Chapel Hill, NC Secretary General, ICTH ix Foreword The advent of synthetic substrates for the study of blood coagulation and fibrinolysis was a significant step forward in the investigation of these systems. Both basic research and clinical laboratory investigations can profit from these advanced tools.
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Handbook of Mouse Auditory Research

From Behavior to Molecular Biology

Author: James F. Willott

Publisher: CRC Press

ISBN: 1420038737

Category: Medical

Page: 736

View: 6688

This unique compilation of chapters reviews a broad range of topics at the cutting edge of hearing research. The authors include many of the top auditory scientists in the world as well as some of the brightest rising stars. Although the book obviously focuses on the exciting, revolutionary work being done with mice, the authors have made a strong effort to provide general background information and present the insights gained from the study of mice in the greater context of auditory research. Each section includes specific procedures, potential problems and their solutions, and tricks of the trade gleaned from the authors. The book contains numerous figures and tables, more than 2,000 references, and much data not previously published. Handbook of Mouse Auditory Research: From Behavior to Molecular Biology provides state-of-the-art research with a clear look at what the future holds.
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Handbook of Research on Systems Biology Applications in Medicine

Author: Daskalaki, Andriani

Publisher: IGI Global

ISBN: 1605660779

Category: Technology & Engineering

Page: 982

View: 520

"This book highlights the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatics, molecular, and biochemical, to address fundamental questions in complex diseases like cancer diabetes but also in ageing"--Provided by publisher.
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The SAGE Handbook of Social Anthropology

Author: Richard Fardon,Oliva Harris,Trevor H J Marchand,Cris Shore,Veronica Strang,Richard Wilson,Mark Nuttall

Publisher: SAGE

ISBN: 144626601X

Category: Social Science

Page: 1184

View: 9594

In two volumes, the SAGE Handbook of Social Anthropology provides the definitive overview of contemporary research in the discipline. It explains the what, where, and how of current and anticipated work in Social Anthropology. With 80 authors, contributing more than 60 chapters, this is the most comprehensive and up-to-date statement of research in Social Anthropology available and the essential point of departure for future projects. The Handbook is divided into four sections: -Part I: Interfaces examines Social Anthropology's disciplinary connections, from Art and Literature to Politics and Economics, from Linguistics to Biomedicine, from History to Media Studies. -Part II: Places examines place, region, culture, and history, from regional, area studies to a globalized world -Part III: Methods examines issues of method; from archives to war zones, from development projects to art objects, and from ethics to comparison -Part IV: Futures anticipates anthropologies to come: in the Brain Sciences; in post-Development; in the Body and Health; and in new Technologies and Materialities Edited by the leading figures in social anthropology, the Handbook includes a substantive introduction by Richard Fardon, a think piece by Jean and John Comaroff, and a concluding last word on futures by Marilyn Strathern. The authors - each at the leading edge of the discipline - contribute in-depth chapters on both the foundational ideas and the latest research. Comprehensive and detailed, this magisterial Handbook overviews the last 25 years of the social anthropological imagination. It will speak to scholars in Social Anthropology and its many related disciplines.
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