Handbook of Pharmaceutical Excipients

Author: Raymond C. Rowe,Paul J. Sheskey,Marian E. Quinn

Publisher: N.A

ISBN: 9780853697947

Category: Medical

Page: 888

View: 7669

An internationally acclaimed reference work recognized as one of the most authoritative and comprehensive sources of information on excipients used in pharmaceutical formulation with this new edition providing 340 excipient monographs. Incorporates information on the uses, and chemical and physical properties of excipients systematically collated from a variety of international sources including: pharmacopeias, patents, primary and secondary literature, websites, and manufacturers' data; extensive data provided on the applications, licensing, and safety of excipients; comprehensively cross-referenced and indexed, with many additional excipients described as related substances and an international supplier's directory and detailed information on trade names and specific grades or types of excipients commercially available.
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Handbook of pharmaceutical excipients

Author: Ainley Wade,Pharmaceutical Society of Great Britain

Publisher: Pharmaceutical Press

ISBN: N.A

Category: Medical

Page: 651

View: 2284

Provides data on the additives used to convert pharmacologically active compounds into dosage forms suitable for administration to patients. Data includes: nonproprietary names, functional category, synonyms, chemical names and CAS Registry number, empirical formula, molecular weight, structural formula, commercial availability, method of manufacture,description, pharmacopeial specifications, typical properties, stability and storage conditions, incompatibilities, safety, handling precautions, regulatory acceptance, applications in pharmaceutical formulation or technology, use, related substances, comments, and specific references.
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Handbook of Pharmaceutical Excipients

Author: Arthur H. Kibbe

Publisher: Amer Pharmacists Assn

ISBN: 9780917330964

Category: Medical

Page: 665

View: 6335

Describes the chemical and physical properties of pharmaceutical excipients. Each monograph contains nonproprietary names, synonyms, chemical name and CAS registry number, empirical formula and molecular weight, structural formula, functional category, applications in pharmaceutical formulation or technology, description, pharmacopeial specifications, typical propertics, stability and storage conditions, incompatibilities, method of manufacture, safety, handling precautions, regulatory status, pharmacopeias, related substances, comments, specific references, general references, and authors.
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Handbook of Pharmaceutical Excipients

Author: Raymond C. Rowe,Paul J. Sheskey,Walter G. Cook,Marian E. Fenton

Publisher: N.A

ISBN: 9780857110275

Category: Medical

Page: 1033

View: 6123

An internationally acclaimed reference work recognized as one of the most authoritative and comprehensive sources of information on excipients used in pharmaceutical formulation with this new edition providing 340 excipient monographs. Incorporates information on the uses, and chemical and physical properties of excipients systematically collated from a variety of international sources including: pharmacopeias, patents, primary and secondary literature, websites, and manufacturers' data; extensive data provided on the applications, licensing, and safety of excipients; comprehensively cross-referenced and indexed, with many additional excipients described as related substances and an international supplier's directory and detailed information on trade names and specific grades or types of excipients commercially available
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Handbook of Pharmaceutical Manufacturing Formulations, Second Edition

Volume One, Compressed Solid Products

Author: Sarfaraz K. Niazi

Publisher: CRC Press

ISBN: 1420081179

Category: Medical

Page: 648

View: 3794

The largest category of pharmaceutical formulations, comprising almost two-thirds of all dosage forms, compressed solids present some of the greatest challenges to formulation scientists. The first volume, Compressed Solid Products, tackles these challenges head on. Highlights from Compressed Solid Products, Volume One include: formulations for more than 200 of the most widely used drugs for all types of release profiles, offering formulators a rare opportunity to start with an optimal composition the essentials of what you need to be aware of when establishing a manufacturing process based on the formulations presented identification and inclusion of the most popular prescription products, a critical list for the selection of products
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CRC Handbook of Food, Drug, and Cosmetic Excipients

Author: Susan C. Smolinske

Publisher: CRC Press

ISBN: 9780849335853

Category: Technology & Engineering

Page: 448

View: 7014

CRC Handbook of Food, Drug, and Cosmetic Excipients provides a comprehensive summary of toxicological issues regarding inactive ingredients in pharmaceutical products, cosmetic products, and food additives. Background information on regulations and labeling requirements for each type of product is provided, and 77 articles critically review human and animal data pertinent to a variety of agents and makes judgments regarding the clinical relevance. The book also identifies at-risk populations, such as neonates, patients with renal failure, and atopic patients. Inactive common pharmaceutical agents and/or foods containing certain ingredients are listed to help physicians counsel hypersensitive patients who must avoid products containing these excipients.
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Handbook of Cosmeceutical Excipients and their Safeties

Author: K Y Heng,T Y Kei,K J Singh,Li Hairui,Poh Ai-Ling,K Lifeng

Publisher: Elsevier

ISBN: 1908818719

Category: Medical

Page: 240

View: 5054

Cosmeceuticals are the latest additions to the health industry and have an ever-expanding market. They are considered to be a marriage between cosmetics and drugs and are defined as preparations applied on the body that may modify the physiological functions of the skin. However, as more cosmeceuticals are being launched in the market and more types of drugs are incorporated into the formulation, the composition of cosmeceuticals is becoming more complex. Handbook of Cosmeceutical Excipients and their Safeties summarises the current evidence relating to cosmeceuticals’ side effects and highlights the important information that practitioners and consumers need to know, as well as ways to avoid the adverse effects of the excipients. Handbook of Cosmeceutical Excipients and their Safeties includes chapters covering topics such as the history of cosmeceuticals and the laws that regulate them, skin permeation, carcinogenicity as a systemic adverse effect and dermatitis as a topical adverse effect. It concludes with an appendix that gives brief information on the potency and permeability of common ingredients in cosmeceuticals. The appendix aims to highlight the maximum allowable quantity of each ingredient to ensure product safety for consumers. The appendix was prepared by compiling the ingredients of 257 products containing more than 500 compounds, collected from a hospital pharmacy in Singapore. Focuses on the practical aspect of adverse effects from cosmeceuticals Explains the regulatory framework of cosmeceuticals Gives an idea of how excipients and drugs in cosmeceuticals enter the skin and methods of control
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Pharmaceutical Excipients

Properties, Functionality, and Applications in Research and Industry

Author: Otilia M. Y. Koo

Publisher: John Wiley & Sons

ISBN: 1118992423

Category: Medical

Page: 352

View: 4603

This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical products formulation. It includes development, characterization methodology, applications, and up-to-date advances through the perspectives of excipients developers, users, and regulatory experts. Covers the sources, characterization, and harmonization of excipients: essential information for optimal excipients selection in pharmaceutical development Describes the physico-chemical properties and biological effects of excipients Discusses chemical classes, safety and toxicity, and formulation Addresses recent efforts in the standardization and harmonization of excipients
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Pharmaceutical Excipients 2001

Handbook of Pharmaceutical Excipients

Author: Pharmaceutical Press,Raymond C. Rowe,Paul J Sheskey,Paul J Weller

Publisher: N.A

ISBN: 9780853694977

Category: Medical

Page: N.A

View: 4161

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Handbook of Pharmaceutical Excipients

Author: Paul J. Sheskey,Walter G. Cook,Colin G. Cable

Publisher: N.A

ISBN: 9780857112712

Category: Excipients

Page: 1216

View: 2669

The Handbook of Pharmaceutical Excipients contains essential data on the physical properties of excipients, their safe use and potential toxicity.
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Pharmaceutical Manufacturing Handbook

Production and Processes

Author: Shayne Cox Gad

Publisher: John Wiley & Sons

ISBN: 9780470259801

Category: Science

Page: 1384

View: 745

This handbook features contributions from a team of expert authors representing the many disciplines within science, engineering, and technology that are involved in pharmaceutical manufacturing. They provide the information and tools you need to design, implement, operate, and troubleshoot a pharmaceutical manufacturing system. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.
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Handbook of Pharmaceutical Granulation Technology, Third Edition

Author: Dilip M. Parikh

Publisher: CRC Press

ISBN: 1616310030

Category: Medical

Page: 676

View: 6084

The Third Edition presents all pharmaceutical industry personnel and those in academia with critical updates on the recent advances in granulation technology and changes in FDA regulatory guidelines. Addressing precisely how these recent innovations and revisions affect unit operation of particle generation and granulation, this text assists the reader in selecting the ideal technology for his/her company’s particular drug delivery system. This knowledge helps ensure that regulatory guidelines are followed and met in a cost-effective manner. Here are just a few of the new topics discussed in this revised and expanded handbook: spray drying nanotechnology biotechnologically derived drugs nutraceuticals controlled release drugs particle engineering supercritical fluids concepts of design space process optimization regulation harmonization by global health authorities process controlexpert systems Process Analytical Technology (PAT) regulatory issues in granulation In addition, all chapters in the Handbook of Pharmaceutical Granulation Technology explore the fundamentals of powder characterization, granulation, and state-of-the-art technologies, modeling, application of expert systems, and manufacturing optimization.
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Handbook of Pharmacy Health Education

Author: Robin J. Harman

Publisher: Pharmaceutical Press

ISBN: 9780853694717

Category: Medical

Page: 299

View: 4782

In recent years there has been increasing awareness of the demands that ill-health places on national resources. As a consequence, there has been a greater emphasis placed on prevention of illness, and an encouragement of health promotion. Pharmacists, since they regularly come into contact with both healthy and sick members of the public, are thus ideally placed to advice and influence people to lead healthy lifestyles and thus possibly prevent future illness. The Handbook of Pharmacy Health Education contains a wealth of information that the health professional, and particularly the pharmacist, can utilise in promoting healthy living. This new edition of the Handbook has been extensively revised by a team of health professionals and reflects changes in practice, therapeutics, and health promotion. An additional new chapter on companion animals and human health has also been included.
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The Magnesium Stearate Handbook

Author: Patrick C. Okoye

Publisher: iUniverse

ISBN: 1532011121

Category: Medical

Page: 110

View: 1146

Magnesium stearate (MgSt) is widely used in cosmetic, food, and pharmaceutical formulations as lubricant in capsule and tablet manufacture at concentrations between 0.25% and 5%. A recent review of the top two hundred prescription drugs showed over 50% contained magnesium stearate. This book covered a broad spectrum of concentration from 1% to 10% for the purpose of presenting their unique properties during powder rheology, tableting, and effect on drug dissolution. MgSt also has both scientifi c and economic signifi cance, given its wide application in global pharmaceutical manufacturing. An understanding of polymorphism (or pseudopolymorphism) in magnesium stearate and the impact on tablet lubrication process and drug dissolution would provide a valuable tool to pharmaceutical scientists during excipient selection process for new product development and even during reformulation of existing products. Preformulation scientists spend a great deal of time reviewing excipients for new product development both in silico and on the bench. As a result, accurate selection of excipients, such as lubricants, could avoid potential issues with clinical batches, product scale-up, and product transfer during commercialization.
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Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry

Author: Vijay Kumar Thakur,Manju Kumari Thakur

Publisher: John Wiley & Sons

ISBN: 111904135X

Category: Technology & Engineering

Page: 552

View: 2934

Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers
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Injectable Drugs Guide

Author: Alistair Gray,Jane Wright,Vincent Goodey

Publisher: Pharmaceutical Press

ISBN: 0853697876

Category: Medical

Page: 907

View: 5745

The administration of drugs by injection is an essential activity that is performed daily in many healthcare settings. This guide provides a user-friendly, single point of reference for healthcare professionals in the safe and effective administration of injectable medicines. Injectable Drugs Guide is designed to support the NPSA risk assessment process and each drug has a risk rating. The book provides a holistic approach to injectable medicines to meet the needs of the many disciplines involved in the clinical use of injectables and also those providing advice about injectable drug use. The online version of this book is available on MedicinesComplete (www.medicinescomplete.com) where content will be regularly updated.
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An Introduction to Clinical Pharmaceutics

Author: Alexander T. Florence

Publisher: Pharmaceutical Press

ISBN: 0853696918

Category: Medical

Page: 179

View: 8302

This textbook considers the role of basic pharmaceutics in determining or modifying clinical outcomes and in explaining the behavior of medicines in the body, including adverse reactions due to formulations and excipients. An Introduction to Clinical Pharmaceutics covers recent developments such as personalised therapies and nanotechnology. All of the principles underpinning clinical pharmaceutics are supported using relevant examples from recent literature and clinical case studies, including issues of: formulation and excipients; surface tension; rheology; solubility; crystallisation and precipitation; aggregation; absorption. Examples and implications of each phenomenon are discussed with a reminder of the underlying pharmaceutics.
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Developing Solid Oral Dosage Forms

Pharmaceutical Theory and Practice

Author: Yihong Qiu,Yisheng Chen,Geoff G.Z. Zhang,Lawrence Yu,Rao V. Mantri

Publisher: Academic Press

ISBN: 0128026375

Category: Medical

Page: 1176

View: 5148

Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more. Written and edited by an international team of leading experts with experience and knowledge across industry, academia, and regulatory settings Includes new chapters covering the pharmaceutical applications of surface phenomenon, predictive biopharmaceutics and pharmacokinetics, the development of formulations for drug discovery support, and much more Presents new case studies throughout, and a section completely devoted to regulatory aspects, including global product regulation and international perspectives
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Polyvinylpyrrolidone Excipients for Pharmaceuticals

Povidone, Crospovidone and Copovidone

Author: Volker Bühler

Publisher: Springer Science & Business Media

ISBN: 9783540234128

Category: Medical

Page: 254

View: 5231

The book describes the properties, analytical methods and the applications of different polyvinylpyrrolidone excipients (povidone, crospovidone, copovidone etc.) for use in pharmaceutical preparations. This group of excipients is one of the most important excipients used in modern technology to produce drugs. The book is intended for all persons working in the research, development and quality control of drugs. It gives a survey of all applications in solid, liquid and semisolid dosage forms including many drug formulation examples and more than 600 references to the literature.
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