Handbook of Pharmaceutical Excipients

Author: Raymond C. Rowe,Paul J. Sheskey,Marian E. Quinn

Publisher: N.A

ISBN: 9780853697947

Category: Medical

Page: 888

View: 9334

An internationally acclaimed reference work recognized as one of the most authoritative and comprehensive sources of information on excipients used in pharmaceutical formulation with this new edition providing 340 excipient monographs. Incorporates information on the uses, and chemical and physical properties of excipients systematically collated from a variety of international sources including: pharmacopeias, patents, primary and secondary literature, websites, and manufacturers' data; extensive data provided on the applications, licensing, and safety of excipients; comprehensively cross-referenced and indexed, with many additional excipients described as related substances and an international supplier's directory and detailed information on trade names and specific grades or types of excipients commercially available.
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Handbook of pharmaceutical excipients

Author: Ainley Wade,Pharmaceutical Society of Great Britain

Publisher: Pharmaceutical Press

ISBN: N.A

Category: Medical

Page: 651

View: 8133

Provides data on the additives used to convert pharmacologically active compounds into dosage forms suitable for administration to patients. Data includes: nonproprietary names, functional category, synonyms, chemical names and CAS Registry number, empirical formula, molecular weight, structural formula, commercial availability, method of manufacture,description, pharmacopeial specifications, typical properties, stability and storage conditions, incompatibilities, safety, handling precautions, regulatory acceptance, applications in pharmaceutical formulation or technology, use, related substances, comments, and specific references.
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Handbook of Pharmaceutical Excipients

Author: Arthur H. Kibbe

Publisher: Amer Pharmacists Assn

ISBN: 9780917330964

Category: Medical

Page: 665

View: 5023

Describes the chemical and physical properties of pharmaceutical excipients. Each monograph contains nonproprietary names, synonyms, chemical name and CAS registry number, empirical formula and molecular weight, structural formula, functional category, applications in pharmaceutical formulation or technology, description, pharmacopeial specifications, typical propertics, stability and storage conditions, incompatibilities, method of manufacture, safety, handling precautions, regulatory status, pharmacopeias, related substances, comments, specific references, general references, and authors.
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Handbook of Pharmaceutical Excipients

Author: Raymond C. Rowe,Paul J. Sheskey,Walter G. Cook,Marian E. Fenton

Publisher: N.A

ISBN: 9780857110275

Category: Medical

Page: 1033

View: 6108

An internationally acclaimed reference work recognized as one of the most authoritative and comprehensive sources of information on excipients used in pharmaceutical formulation with this new edition providing 340 excipient monographs. Incorporates information on the uses, and chemical and physical properties of excipients systematically collated from a variety of international sources including: pharmacopeias, patents, primary and secondary literature, websites, and manufacturers' data; extensive data provided on the applications, licensing, and safety of excipients; comprehensively cross-referenced and indexed, with many additional excipients described as related substances and an international supplier's directory and detailed information on trade names and specific grades or types of excipients commercially available
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Handbook of Cosmeceutical Excipients and their Safeties

Author: K Y Heng,T Y Kei,K J Singh,Li Hairui,Poh Ai-Ling,K Lifeng

Publisher: Elsevier

ISBN: 1908818719

Category: Medical

Page: 240

View: 2205

Cosmeceuticals are the latest additions to the health industry and have an ever-expanding market. They are considered to be a marriage between cosmetics and drugs and are defined as preparations applied on the body that may modify the physiological functions of the skin. However, as more cosmeceuticals are being launched in the market and more types of drugs are incorporated into the formulation, the composition of cosmeceuticals is becoming more complex. Handbook of Cosmeceutical Excipients and their Safeties summarises the current evidence relating to cosmeceuticals’ side effects and highlights the important information that practitioners and consumers need to know, as well as ways to avoid the adverse effects of the excipients. Handbook of Cosmeceutical Excipients and their Safeties includes chapters covering topics such as the history of cosmeceuticals and the laws that regulate them, skin permeation, carcinogenicity as a systemic adverse effect and dermatitis as a topical adverse effect. It concludes with an appendix that gives brief information on the potency and permeability of common ingredients in cosmeceuticals. The appendix aims to highlight the maximum allowable quantity of each ingredient to ensure product safety for consumers. The appendix was prepared by compiling the ingredients of 257 products containing more than 500 compounds, collected from a hospital pharmacy in Singapore. Focuses on the practical aspect of adverse effects from cosmeceuticals Explains the regulatory framework of cosmeceuticals Gives an idea of how excipients and drugs in cosmeceuticals enter the skin and methods of control
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Pharmaceutical Excipients 2001

Handbook of Pharmaceutical Excipients

Author: Pharmaceutical Press,Raymond C. Rowe,Paul J Sheskey,Paul J Weller

Publisher: N.A

ISBN: 9780853694977

Category: Medical

Page: N.A

View: 5284

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CRC Handbook of Food, Drug, and Cosmetic Excipients

Author: Susan C. Smolinske

Publisher: CRC Press

ISBN: 9780849335853

Category: Technology & Engineering

Page: 448

View: 8894

CRC Handbook of Food, Drug, and Cosmetic Excipients provides a comprehensive summary of toxicological issues regarding inactive ingredients in pharmaceutical products, cosmetic products, and food additives. Background information on regulations and labeling requirements for each type of product is provided, and 77 articles critically review human and animal data pertinent to a variety of agents and makes judgments regarding the clinical relevance. The book also identifies at-risk populations, such as neonates, patients with renal failure, and atopic patients. Inactive common pharmaceutical agents and/or foods containing certain ingredients are listed to help physicians counsel hypersensitive patients who must avoid products containing these excipients.
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Handbook of Pharmaceutical Excipients

Author: Paul J. Sheskey,Walter G. Cook,Colin G. Cable

Publisher: N.A

ISBN: 9780857112712

Category: Excipients

Page: 1216

View: 5476

The Handbook of Pharmaceutical Excipients contains essential data on the physical properties of excipients, their safe use and potential toxicity.
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Handbook of Pharmaceutical Granulation Technology

Author: Dilip M. Parikh

Publisher: CRC Press

ISBN: 9780824798826

Category: Medical

Page: 528

View: 5217

Integrating the basic principles and industrial practices of pharmaceutical granulation production, this book discusses technologies and demonstrates cost-effective approaches to manufacturing solid-dosage forms with content uniformity and consistent physical properties while complying with regulatory requirements. Specialists from pharmaceutical companies, academia, and the U.S. Drug Regulatory Affairs agency address current and changing practices in industrial drug granulation production. Text, charts, figures, and photographs illustrate the pros and cons of diverse methods and technologies for accurately achieving strong bonding of particles in tablets and capsules.
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Pharmaceutical Manufacturing Handbook

Production and Processes

Author: Shayne Cox Gad

Publisher: John Wiley & Sons

ISBN: 9780470259801

Category: Science

Page: 1384

View: 6178

This handbook features contributions from a team of expert authors representing the many disciplines within science, engineering, and technology that are involved in pharmaceutical manufacturing. They provide the information and tools you need to design, implement, operate, and troubleshoot a pharmaceutical manufacturing system. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.
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Handbook of Pharmaceutical Manufacturing Formulations

Liquid Products (Volume 3 of 6)

Author: Sarfaraz K. Niazi

Publisher: CRC Press

ISBN: 9781420048452

Category: Medical

Page: 256

View: 8796

The third volume in the six-volume Handbook of Pharmaceutical Manufacturing Formulations, this book covers liquid drugs, which include formulations of non-sterile drugs administered by any route in the form of solutions (monomeric and multimeric), suspensions (powder and liquid), drops, extracts, elixirs, tinctures, paints, sprays, colloidons, emulsions, aerosols, and other fluid preparations from publicly available but widely dispersed information from FDA New Drug Applications (NDA), patent applications, and other sources of generic and proprietary formulations. Each entry begins with a fully validated scaleable manufacturing formula and a summary of manufacturing process. The book provides a detailed discussion on the difficulties encountered in formulating and manufacturing liquid drugs and the common elements of formulation. The section on regulatory and manufacturing guidance deals with the topics of changes to approved NDAs and aNDAs, post-approval changes to semisolid drugs, global manufacturing practices and guidelines, compliance program guidance manual for FDA staff covering drug manufacturing inspections program, waiver of in vivo bioavailability studies for immediate release solid drugs based on a biopharmaceutics classification, in addition to providing quick tips on resolving the common problems in formulating uncompressed drugs.
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Pharmaceutical Excipients

Properties, Functionality, and Applications in Research and Industry

Author: Otilia M. Y. Koo

Publisher: John Wiley & Sons

ISBN: 1118992423

Category: Medical

Page: 352

View: 9658

This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical products formulation. It includes development, characterization methodology, applications, and up-to-date advances through the perspectives of excipients developers, users, and regulatory experts. Covers the sources, characterization, and harmonization of excipients: essential information for optimal excipients selection in pharmaceutical development Describes the physico-chemical properties and biological effects of excipients Discusses chemical classes, safety and toxicity, and formulation Addresses recent efforts in the standardization and harmonization of excipients
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Handbook of Pharmacy Health Education

Author: Robin J. Harman

Publisher: Pharmaceutical Press

ISBN: 9780853694717

Category: Medical

Page: 299

View: 3684

In recent years there has been increasing awareness of the demands that ill-health places on national resources. As a consequence, there has been a greater emphasis placed on prevention of illness, and an encouragement of health promotion. Pharmacists, since they regularly come into contact with both healthy and sick members of the public, are thus ideally placed to advice and influence people to lead healthy lifestyles and thus possibly prevent future illness. The Handbook of Pharmacy Health Education contains a wealth of information that the health professional, and particularly the pharmacist, can utilise in promoting healthy living. This new edition of the Handbook has been extensively revised by a team of health professionals and reflects changes in practice, therapeutics, and health promotion. An additional new chapter on companion animals and human health has also been included.
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Developing Solid Oral Dosage Forms

Pharmaceutical Theory and Practice

Author: Yihong Qiu,Yisheng Chen,Geoff G.Z. Zhang,Lawrence Yu,Rao V. Mantri

Publisher: Academic Press

ISBN: 0128026375

Category: Medical

Page: 1176

View: 1894

Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more. Written and edited by an international team of leading experts with experience and knowledge across industry, academia, and regulatory settings Includes new chapters covering the pharmaceutical applications of surface phenomenon, predictive biopharmaceutics and pharmacokinetics, the development of formulations for drug discovery support, and much more Presents new case studies throughout, and a section completely devoted to regulatory aspects, including global product regulation and international perspectives
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Pharmaceutical Stress Testing

Predicting Drug Degradation, Second Edition

Author: Steven W. Baertschi,Karen M. Alsante,Robert A. Reed

Publisher: CRC Press

ISBN: 1439801800

Category: Medical

Page: 612

View: 9703

The second edition of Pharmaceutical Stress Testing: Predicting Drug Degradation provides a practical and scientific guide to designing, executing and interpreting stress testing studies for drug substance and drug product. This is the only guide available to tackle this subject in-depth. The Second Edition expands coverage from chemical stability into the physical aspects of stress testing, and incorporates the concept of Quality by Design into the stress testing construct / framework. It has been revised and expanded to include chapters on large molecules, such as proteins and antibodies, and it outlines the changes in stress testing that have emerged in recent years. Key features include: A renowned Editorial team and contributions from all major drug companies, reflecting a wealth of experience. 10 new chapters, including Stress Testing and its relationship to the assessment of potential genotoxic degradants, combination drug therapies, proteins, oligonucleotides, physical changes and alternative dosage forms such as liposomal formulations Updated methodologies for predicting drug stability and degradation pathways Best practice models to follow An expanded Frequently Asked Questions section This is an essential reference book for Pharmaceutical Scientists and those working in Quality Assurance and Drug Development (analytical sciences, formulations, chemical process, project management).
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An Introduction to Clinical Pharmaceutics

Author: Alexander T. Florence

Publisher: Pharmaceutical Press

ISBN: 0853696918

Category: Medical

Page: 179

View: 998

This textbook considers the role of basic pharmaceutics in determining or modifying clinical outcomes and in explaining the behavior of medicines in the body, including adverse reactions due to formulations and excipients. An Introduction to Clinical Pharmaceutics covers recent developments such as personalised therapies and nanotechnology. All of the principles underpinning clinical pharmaceutics are supported using relevant examples from recent literature and clinical case studies, including issues of: formulation and excipients; surface tension; rheology; solubility; crystallisation and precipitation; aggregation; absorption. Examples and implications of each phenomenon are discussed with a reminder of the underlying pharmaceutics.
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Handbook of Cosmetic Science and Technology, Fourth Edition

Author: André O. Barel,Marc Paye,Howard I. Maibach

Publisher: CRC Press

ISBN: 1842145649

Category: Medical

Page: 725

View: 7181

Written by experienced and internationally renowned contributors, this is the fourth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for skin, hair, and nails. New to this fourth edition are chapters on dermatocosmetic vehicles, surface film, causes and measurement of skin aging, make-up products, skin healing, cosmetics in sports, cosmetotextiles, nutricosmetics, natural ingredients, cosmeceuticals, and regulatory vigilance.
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Quality Assurance of Aseptic Preparation Services

Author: Alison M. Beaney

Publisher: Pharmaceutical Press

ISBN: 9780853696155

Category: Medical

Page: 154

View: 3153

It is now widely recognised that preparation of intravenous injections should be carried out in pharmacy departments rather than on wards, using defined standards. This new edition of Quality Assurance of Aseptic Preparation Services provides information and up-to-date national guidance on unlicensed aseptic preparation.
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Injectable Drugs Guide

Author: Alistair Gray,Jane Wright,Vincent Goodey

Publisher: Pharmaceutical Press

ISBN: 0853697876

Category: Medical

Page: 907

View: 5771

The administration of drugs by injection is an essential activity that is performed daily in many healthcare settings. This guide provides a user-friendly, single point of reference for healthcare professionals in the safe and effective administration of injectable medicines. Injectable Drugs Guide is designed to support the NPSA risk assessment process and each drug has a risk rating. The book provides a holistic approach to injectable medicines to meet the needs of the many disciplines involved in the clinical use of injectables and also those providing advice about injectable drug use. The online version of this book is available on MedicinesComplete (www.medicinescomplete.com) where content will be regularly updated.
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