Genome

The Autobiography of a Species in 23 Chapters

Author: Matt Ridley

Publisher: Harper Collins

ISBN: 0062253468

Category: Science

Page: 368

View: 5712

The genome's been mapped. But what does it mean? Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Matt Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.
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Genome

The Autobiography of a Species in 23 Chapters

Author: Matt Ridley

Publisher: Harper Collins

ISBN: 0060894083

Category: Science

Page: 368

View: 9855

The genome's been mapped. But what does it mean? Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Matt Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.
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Genome: The Autobiography of a Species in 23 Chapters

Author: Matt Ridley

Publisher: HarperCollins UK

ISBN: 0007381840

Category: Science

Page: 352

View: 7283

The most important investigation of genetic science since The Selfish Gene, from the author of the critically acclaimed and best-selling The Red Queen and The Origins of Virtue.
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A Life Decoded

My Genome: My Life

Author: J. Craig Venter

Publisher: Penguin

ISBN: 1101202564

Category: Biography & Autobiography

Page: 400

View: 3421

The triumphant memoir of the man behind one of the greatest feats in scientific history Of all the scientific achievements of the past century, perhaps none can match the deciphering of the human genetic code, both for its technical brilliance and for its implications for our future. In A Life Decoded, J. Craig Venter traces his rise from an uninspired student to one of the most fascinating and controversial figures in science today. Here, Venter relates the unparalleled drama of the quest to decode the human genome?a goal he predicted he could achieve years earlier and more cheaply than the government-sponsored Human Genome Project, and one that he fulfilled in 2001. A thrilling story of detection, A Life Decoded is also a revealing, and often troubling, look at how science is practiced today.
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The Evolution of Everything

How New Ideas Emerge

Author: Matt Ridley

Publisher: HarperCollins

ISBN: 0062296027

Category: Business & Economics

Page: 368

View: 9077

The New York Times bestselling author of The Rational Optimist and Genome returns with a fascinating argument for evolution that definitively dispels a dangerous, widespread myth: that we can command and control our world. Human society evolves. Change in technology, language, morality, and society is incremental, inexorable, gradual, and spontaneous. It follows a narrative, going from one stage to the next; it creeps rather than jumps; it has its own spontaneous momentum rather than being driven from outside; it has no goal or end in mind; and it largely happens by trial and error—a version of natural selection. Much of the human world is the result of human action but not of human design: it emerges from the interactions of millions, not from the plans of a few. Drawing on fascinating evidence from science, economics, history, politics, and philosophy, Matt Ridley demolishes conventional assumptions that the great events and trends of our day are dictated by those on high, whether in government, business, academia, or organized religion. On the contrary, our most important achievements develop from the bottom up. Just as skeins of geese form Vs in the sky without meaning to and ter-mites build mud cathedrals without architects, so brains take shape without brain-makers, learning happens without teaching, and morality changes for no reason other than the prevailing fashion. Although we neglect, defy, and ignore them, bottom-up trends shape the world. The Industrial Revolution, cell phones, the rise of Asia, and the Internet were never planned; they happened. Languages emerged and evolved by a form of natural selection, as did common law. Torture, racism, slavery, and pedophilia—all once widely regarded as acceptable—are now seen as immoral despite the decline of religion in recent decades. In this wide-ranging and erudite book, Ridley brilliantly makes the case for evolution, rather than design, as the force that has shaped much of our culture, our technology, our minds, and that even now is shaping our future. As compelling as it is controversial, as authoritative as it is ambitious, Ridley’s deeply thought-provoking book will change the way we think about the world and how it works.
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The Epigenetics Revolution

How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance

Author: Nessa Carey

Publisher: Columbia University Press

ISBN: 0231530714

Category: Science

Page: 352

View: 6232

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
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Nature Via Nurture

Genes, Experience, and What Makes Us Human

Author: Matt Ridley

Publisher: Harper Collins

ISBN: 0060006781

Category: Science

Page: 326

View: 6348

Documents the 2001 discovery that there are fewer genes in a human genome than previously thought and considers the argument that nurture elements are also largely responsible for human behavior.
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The Human Genome Project

Deciphering the Blueprint of Heredity

Author: Necia Grant Cooper

Publisher: University Science Books

ISBN: 9780935702293

Category: Medical

Page: 360

View: 6037

"For centuries, humans have pondered the mysteries of inheritance and heredity. Questions and observations concerning inheritance can be found throughout history, from the remarkable (if discredited) theory of pangenesis, as advanced by Hippocrates in the fifth century B.C., to Gregor Mendel keenly observing the traits of generations of garden peas. Over the course of the last 100 years, great advances have been made in unraveling these mysteries, culminating now in one of the most challenging projects in the history of science - the Human Genome Project." "Unprecedented in its scope, the Human Genome Project is an international effort that seeks to create a detailed map of human DNA. This unique book, written to be accessible to the general reader, first provides a basic introduction to the ideas underlying classical and molecular genetics before going on to describe the purpose of the Human Genome Project, its approach, its triumphs, its technological pitfalls, and its ultimate implications for society. Candid discussions by key members of the scientific community - including skeptics as well as proponents of the project - bring to life the many difficult questions this research effort has raised. Not least among these are questions of ethics, since the completed map will provide genetic engineers with heretofore impossible capabilities; one might imagine a world, for instance, in which disease-causing or disabling genes could be located and eliminated from the genome." "Through photographs, micrographs, and hundreds of beautifully rendered illustrations, many of them in color, this book creates a sense of shared excitement for the reader who follows the story of this fascinating project into the twenty-first century."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
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Drawing the Map of Life

Inside the Human Genome Project

Author: Victor K. McElheny,K McElheny

Publisher: Basic Books

ISBN: 0465032605

Category: Science

Page: 384

View: 5083

Drawing the Map of Life is the dramatic story of the Human Genome Project from its origins, through the race to order the 3 billion subunits of DNA, to the surprises emerging as scientists seek to exploit the molecule of heredity. It’s the first account to deal in depth with the intellectual roots of the project, the motivations that drove it, and the hype that often masked genuine triumphs. Distinguished science journalist Victor McElheny offers vivid, insightful profiles of key people, such as David Botstein, Eric Lander, Francis Collins, James Watson, Michael Hunkapiller, and Craig Venter. McElheny also shows that the Human Genome Project is a striking example of how new techniques (such as restriction enzymes and sequencing methods) often arrive first, shaping the questions scientists then ask. Drawing on years of original interviews and reporting in the inner circles of biological science, Drawing the Map of Life is the definitive, up-to-date story of today’s greatest scientific quest. No one who wishes to understand genome mapping and how it is transforming our lives can afford to miss this book.
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Genome

The Story of the Most Astonishing Scientific Adventure of Our Time—the Attempt to Map All the Genes in the Human Body

Author: Jerry E. Bishop,Michael Waldholz

Publisher: Open Road Media

ISBN: 1497607531

Category: Science

Page: 422

View: 6837

An “invaluable [and] highly readable” account of the quest to map our DNA, the blueprint for life—and what it means for our future ( The Philadelphia Inquirer). Genome tells the story of the most ambitious scientific adventure of our time. By gradually isolating and identifying all the genes in the human body—the blueprint for life—scientists are closing in on the ability to effectively treat and prevent nearly every disease that strikes man, from muscular dystrophy, diabetes, and cancer to heart ailments, alcoholism, and even mental illness. Such discoveries will change the course of human life. At the same time, they raise profound ethical questions that have tremendous implications: Can insurance companies demand genetic tests to determine who poses a health risk? Should parents be able to choose their baby’s sex or eye color? Will employers screen out potential employees who are genetically susceptible to occupational health problems? An exciting true tale of discovery that is revolutionizing our world, Genome helps us understand our future.
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Promising Genomics

Iceland and DeCODE Genetics in a World of Speculation

Author: Michael Fortun

Publisher: Univ of California Press

ISBN: 0520247515

Category: Medical

Page: 330

View: 2770

Part detective story, part exposé and part travelogue, this book investigates one of the signature biotech stories of our time and, in doing so, opens a window onto the world of genome science. Fortun examines how deCODE Genetics in Iceland became one of the wealthiest, and most scandalous, companies of its kind.
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Francis Crick

Discoverer of the Genetic Code

Author: Matt Ridley

Publisher: Harper Collins

ISBN: 0062200666

Category: Biography & Autobiography

Page: 224

View: 8669

Francis Crick—the quiet genius who led a revolution in biology by discovering, quite literally, the secret of life—will be bracketed with Galileo, Darwin, and Einstein as one of the greatest scientists of all time. In his fascinating biography of the scientific pioneer who uncovered the genetic code—the digital cipher at the heart of heredity that distinguishes living from non-living things—acclaimed bestselling science writer Matt Ridley traces Crick's life from middle-class mediocrity in the English Midlands through a lackluster education and six years designing magnetic mines for the Royal Navy to his leap into biology at the age of thirty-one and its astonishing consequences. In the process, Ridley sheds a brilliant light on the man who forever changed our world and how we understand it.
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What's in Your Genes?

From the Color of Your Eyes to the Length of Your Life, a Revealing Look at Your Genetic Traits

Author: Katie McKissick

Publisher: Simon and Schuster

ISBN: 1440567646

Category: Reference

Page: 256

View: 2363

A crash course in genetics! Everyone knows that if you come from a family of brunettes, you're likely to be born with brown hair. But did you know your hair color may also affect how often you get sunburned? Or how often you need to take vitamin supplements? What's in Your Genes? goes beyond Gregor Mendel and dominant/recessive genes to show you all the ins and outs of what determines your DNA. Each entry provides you with a sneak peek into your DNA sequence and teaches you exactly how your body is able to create that wonderful you-ness that no one else has. From your tastebuds to your eye color to your obsession with clinical-strength deodorants, this book not only guides you through the history and study of genetics, but also shows you how those four little letters in your DNA make you who you are. Complete with imaginative illustrations, What's in Your Genes? reveals all there is to know about heredity--like the science behind vibrant red hair, perfect teeth, and your ability to see in color.
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The Human Genome

Author: Julia E. Richards,R. Scott Hawley

Publisher: Academic Press

ISBN: 9780080918655

Category: Science

Page: 420

View: 8803

Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome,2E includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information . Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students Full, 4-color illustration program enhances and reinforces key concepts and themes Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers
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The Red Queen

Sex and the Evolution of Human Nature

Author: Matt Ridley

Publisher: Harper Collins

ISBN: 0062200712

Category: Science

Page: 416

View: 6375

Referring to Lewis Carroll's Red Queen from Through the Looking-Glass, a character who has to keep running to stay in the same place, Matt Ridley demonstrates why sex is humanity's best strategy for outwitting its constantly mutating internal predators. The Red Queen answers dozens of other riddles of human nature and culture -- including why men propose marriage, the method behind our maddening notions of beauty, and the disquieting fact that a woman is more likely to conceive a child by an adulterous lover than by her husband. Brilliantly written, The Red Queen offers an extraordinary new way of interpreting the human condition and how it has evolved.
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The $1,000 Genome

The Revolution in DNA Sequencing and the New Era of Personalized Medicine

Author: Kevin Davies

Publisher: Simon and Schuster

ISBN: 1416569618

Category: Science

Page: 352

View: 5492

Since the conclusion of the Human Genome Project in 2003, scientists have been racing towards a grand goal: offering individuals a decoding of their complete genetic makeup for just $1,000. As Kevin Davies reveals in this exquisitely reported account, the $1,000 genome will be a reality by 2011 and it will usher in a whole new era of personalized, genomic medicine. Capable of presenting much more advanced information than the current crop of cheek-swab services, the $1,000 complete genome raises some extraordinary possibilities. We will be able to learn if we have genes that predispose us to a host of diseases, and to take a wide range of preventative measures. Drug companies may be able to create versions of drugs tailored specifically to our individual DNA. But we may also face the psychological burden of learning that we have the gene for an incurable disease, such as Parkinson’s. Acclaimed author Kevin Davies introduces the pioneers of this medical revolution and probes deeply into both the medical benefits and ethical issues of personal genetic testing, also exploring the psychological complexities of learning one’s DNA results, based on both his own experience of being tested and that of a number of others. The $1,000 Genome is an indispensable guide to the new era of personalized medicine.
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The Human Genome Project

Cracking the Genetic Code of Life

Author: Thomas F. Lee

Publisher: Springer

ISBN: 1489960228

Category: Medical

Page: 323

View: 8184

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DNA

The Secret of Life

Author: James D. Watson,Andrew Berry

Publisher: Knopf

ISBN: 0307521486

Category: Science

Page: 464

View: 6270

Fifty years ago, James D. Watson, then just twentyfour, helped launch the greatest ongoing scientific quest of our time. Now, with unique authority and sweeping vision, he gives us the first full account of the genetic revolution—from Mendel’s garden to the double helix to the sequencing of the human genome and beyond. Watson’s lively, panoramic narrative begins with the fanciful speculations of the ancients as to why “like begets like” before skipping ahead to 1866, when an Austrian monk named Gregor Mendel first deduced the basic laws of inheritance. But genetics as we recognize it today—with its capacity, both thrilling and sobering, to manipulate the very essence of living things—came into being only with the rise of molecular investigations culminating in the breakthrough discovery of the structure of DNA, for which Watson shared a Nobel prize in 1962. In the DNA molecule’s graceful curves was the key to a whole new science. Having shown that the secret of life is chemical, modern genetics has set mankind off on a journey unimaginable just a few decades ago. Watson provides the general reader with clear explanations of molecular processes and emerging technologies. He shows us how DNA continues to alter our understanding of human origins, and of our identities as groups and as individuals. And with the insight of one who has remained close to every advance in research since the double helix, he reveals how genetics has unleashed a wealth of possibilities to alter the human condition—from genetically modified foods to genetically modified babies—and transformed itself from a domain of pure research into one of big business as well. It is a sometimes topsy-turvy world full of great minds and great egos, driven by ambitions to improve the human condition as well as to improve investment portfolios, a world vividly captured in these pages. Facing a future of choices and social and ethical implications of which we dare not remain uninformed, we could have no better guide than James Watson, who leads us with the same bravura storytelling that made The Double Helix one of the most successful books on science ever published. Infused with a scientist’s awe at nature’s marvels and a humanist’s profound sympathies, DNA is destined to become the classic telling of the defining scientific saga of our age.
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The Origins of Virtue

Human Instincts and the Evolution of Cooperation

Author: Matt Ridley

Publisher: Penguin Paperbacks

ISBN: 9780140264456

Category: Science

Page: 295

View: 4265

Suggests a biological basis for the social organization and cooperation shown by the human race, and traces the evolution of society
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