Design & Development of Biological, Chemical, Food and Pharmaceutical Products

Author: Johannes A. Wesselingh,Soren Kiil,Martin E. Vigild

Publisher: John Wiley & Sons

ISBN: 0470517786

Category: Technology & Engineering

Page: 310

View: 3635

Design and Development of Biological, Chemical, Food and Pharmaceutical Products has been developed from course material from the authors’ course in Chemical and Biochemical Product Design which has been running at the Technical University Denmark for years. The book draws on the authors’ years of experience in academia and industry to provide an accessible introduction to this field, approaching product development as a subject in its own right rather than a sideline of process engineering In this subject area, practical experience is the key to learning and this textbook provides examples and techniques to help the student get the best out of their projects. Design and Development of Biological, Chemical, Food and Pharma Products aims to aid students in developing good working habits for product development. Students are challenged with examples of real problems that they might encounter as engineers. Written in an informal, student-friendly tone, this unique book includes examples of real products and experiences from real companies to bring the subject alive for the student as well as placing emphasis on problem solving and team learning to set a foundation for a future in industry. The book includes an introduction to the subject of Colloid Science, which is important in product development, but neglected in many curricula. Knowledge of engineering calculus and basic physical chemistry as well as basic inorganic and organic chemistry are assumed. An invaluable text for students of product design in chemical engineering, biochemistry, biotechnology, pharmaceutical sciences and product development. Uses many examples and case studies drawn from a range of industries. Approaches product development as a subject in its own right rather than a sideline of process engineering Emphasizes a problem solving and team learning approach. Assumes some knowledge of calculus, basic physical chemistry and basic transport phenomena as well as some inorganic and organic chemistry.
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Pharmaceutical Design And Development

A Molecular Biology Approach

Author: T V Ramabhadran

Publisher: CRC Press

ISBN: 0203984153

Category: Medical

Page: 288

View: 7407

This volume aims to introduce researchers in pharmaceutical and allied industries to the concepts and latest developments in the application of biotechnology recombinant DNA and monoclonal antibodies to drug development.
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Design and Development of New Nanocarriers

Author: Alexandru Mihai Grumezescu

Publisher: William Andrew

ISBN: 0128136286

Category: Science

Page: 766

View: 3041

Design and Development of New Nanocarriers focuses on the design and development of new nanocarriers used in pharmaceutical applications that have emerged in recent years. In particular, the pharmaceutical uses of microfluidic techniques, supramolecular design of nanocapsules, smart hydrogels, polymeric micelles, exosomes and metal nanoparticles are discussed in detail. Written by a diverse group of international researchers, this book is a valuable reference resource for those working in both biomaterials science and the pharmaceutical industry. Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry
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Design and Development of Aircraft Systems

Author: Ian Moir,Allan Seabridge

Publisher: John Wiley & Sons

ISBN: 1118469143

Category: Technology & Engineering

Page: 336

View: 2033

Now covering both conventional and unmanned systems, this isa significant update of the definitive book on aircraft systemdesign Design and Development of Aircraft Systems, SecondEdition is for people who want to understand how industrydevelops the customer requirement into a fully integrated, tested,and qualified product that is safe to fly and fit for purpose. Thisedition has been updated to take into account the growth ofunmanned air vehicles, together with updates to all chapters tobring them in line with current design practice and technologies astaught on courses at BAE Systems and Cranfield, Bristol andLoughborough universities in the UK. Design and Development of Aircraft Systems, SecondEdition Provides a holistic view of aircraft system design describingthe interaction between all of the subsystems such as fuel system,navigation, flight control etc. Covers all aspects of design including systems engineering,design drivers, systems architectures, systems integration,modelling of systems, practical considerations, & systemsexamples. Incorporates essential new material on Unmanned AircraftSystems (UAS). Design and Development of Aircraft Systems,Second Edition has been written to be generic and not todescribe any single process. It aims to complement othervolumes in the Wiley Aerospace Series, in particular AircraftSystems, Third Edition and Civil Avionics Systems by thesame authors, and will inform readers of the work that is carriedout by engineers in the aerospace industry to produce innovativeand challenging – yet safe and reliable – systems andaircraft. Essential reading for Aerospace Engineers.
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Design and Development of Affordable Healthcare Technologies

Author: Bit, Arindam

Publisher: IGI Global

ISBN: 1522549706

Category: Medical

Page: 388

View: 708

Technological advancements in the last few decades have significantly revolutionized the healthcare industry, resulting in life expectancy improvement in human beings. The use of automated machines in healthcare has reduced human errors and has notably improved disease diagnosis efficiency. Design and Development of Affordable Healthcare Technologies provides emerging research on biomedical instrumentation, bio-signal processing, and device development within the healthcare industry. This book provides insight into various subjects including patient monitoring, medical imaging, and disease classification. This book is a vital reference source for medical professionals, biomedical engineers, scientists, researchers, and medical students interested in the comprehensive research on the advancements in healthcare technologies.
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Design and Development of Medical Electronic Instrumentation

A Practical Perspective of the Design, Construction, and Test of Medical Devices

Author: David Prutchi,Michael Norris

Publisher: John Wiley & Sons

ISBN: 0471681830

Category: Technology & Engineering

Page: 461

View: 8683

Design and Development of Medical Electronic Instrumentation fills a gap in the existing medical electronic devices literature by providing background and examples of how medical instrumentation is actually designed and tested. The book includes practical examples and projects, including working schematics, ranging in difficulty from simple biopotential amplifiers to computer-controlled defibrillators. Covering every stage of the development process, the book provides complete coverage of the practical aspects of amplifying, processing, simulating and evoking biopotentials. In addition, two chapters address the issue of safety in the development of electronic medical devices, and providing valuable insider advice.
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Protein Design and the Development of New Therapeutics and Vaccines

Author: Jerry B. Hook,George Poste

Publisher: Springer Science & Business Media

ISBN: 146845739X

Category: Medical

Page: 512

View: 6147

Based on a symposium held November 1988, in King of Prussia, Penn. Among the topics: structural analysis of proteins, protein folding and stability, receptor design and regulation, guanine nucleotide binding protein family, modeling and structure prediction in macromolecules, protein engineering and
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Biomechatronic Design in Biotechnology

A Methodology for Development of Biotechnological Products

Author: Carl-Fredrik Mandenius,Mats Björkman

Publisher: John Wiley & Sons

ISBN: 1118067134

Category: Technology & Engineering

Page: 256

View: 4960

“... a must-read for all modern bio-scientists and engineers working in the field of biotechnology.” – Biotechnology Journal, 2012, 7 A cutting-edge guide on the fundamentals, theory, and applications of biomechatronic design principles Biomechatronic Design in Biotechnology presents a complete methodology of biomechatronics, an emerging variant of the mechatronics field that marries biology, electronics, and mechanics to create products where biological and biochemical, technical, human, management-and-goal, and information systems are combined and integrated in order to solve a mission that fulfills a human need. A biomechatronic product includes a biological, mechanical, and electronic part. Beginning with an overview of the fundamentals and theory behind biomechatronic technology, this book describes how general engineering design science theory can be applied when designing a technical system where biological species or components are integrated. Some research methods explored include schemes and matrices for analyzing the functionality of the designed products, ranking methods for screening and scoring the best design solutions, and structuring graphical tools for a thorough investigation of the subsystems and sub-functions of products. This insightful guide also: Discusses tools for creating shorter development times, thereby reducing the need for prototype testing and verification Presents case study-like examples of the technology used such as a surface plasmon resonance sensor and a robotic cell culturing system for human embryonic stem cells Provides an interdisciplinary and unifying approach of the many fields of engineering and biotechnology used in biomechatronic design By combining designs between traditional electronic and mechanical subsystems and biological systems, this book demonstrates how biotechnology and bioengineering design can utilize and benefit from commonly used design tools— and benefit humanity itself.
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Biopharmaceutical Drug Design and Development

Author: Susanna Wu-Pong,Yon Rojanasakul

Publisher: Springer Science & Business Media

ISBN: 9781597455329

Category: Medical

Page: 375

View: 1598

This book provides a comprehensive examination of the newest biopharmaceutical drugs. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, and contains a review of the Human Genome Project.
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Data Integration in the Life Sciences

First International Workshop, DILS 2004, Leipzig, Germany, March 25-26, 2004, Proceedings

Author: Erhard Rahm

Publisher: Springer Science & Business Media

ISBN: 3540213007

Category: Computers

Page: 219

View: 2566

This book constitutes the refereed proceedings of the First International Workshop on Data Integration in the Life Sciences, DILS 2004, held in Leipzig, Germany, in March 2004. The 13 revised full papers and 2 revised short papers presented were carefully reviewed and selected from many submissions. The papers are organized in topical sections on scientific and clinical workflows, ontologies and taxonomies, indexing and clustering, integration tools and systems, and integration techniques.
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Transport Phenomena in Biomedical Engineering: Artifical organ Design and Development, and Tissue Engineering

Author: Kal Sharma

Publisher: McGraw Hill Professional

ISBN: 0071663983

Category: Technology & Engineering

Page: 512

View: 9852

A Cutting-Edge Guide to Applying Transport Phenomena Principles to Bioengineering Systems Transport Phenomena in Biomedical Engineering: Artificial Order Design and Development and Tissue Engineering explains how to apply the equations of continuity, momentum, energy, and mass to human anatomical systems. This authoritative resource presents solutions along with term-by-term medical significance. Worked exercises illustrate the equations derived, and detailed case studies highlight real-world examples of artificial organ design and human tissue engineering. Coverage includes: Fundamentals of fluid mechanics and principles of molecular diffusion Osmotic pressure, solvent permeability, and solute transport Rheology of blood and transport Gas transport Pharmacokinetics Tissue design Bioartificial organ design and immunoisolation Bioheat transport 541 end-of-chapter exercises and review questions 106 illustrations 1,469 equations derived from first principles
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New Approaches in Cancer Pharmacology: Drug Design and Development

Author: Paul Workman

Publisher: Springer Science & Business Media

ISBN: 3642790887

Category: Medical

Page: 97

View: 967

The European School of Oncology came into existence to respond to a need for information, education and training in the field of the diagnosis and treatment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidisciplinary approach which is difficult for the Universities to put into practice since their system is mainly disciplinary orientated. Secondly, the rate of technological development that impinges on the diagnosis and treatment of cancer has been so rapid that it is not an easy task for medical faculties to adapt their curricula flexibly. With its residential courses for organ pathologies and the seminars on new techniques (laser, monoclonal antibodies, imaging techniques etc.) or on the principal therapeutic controversies (conservative or mutilating surgery, primary or adjuvant chemotherapy, radiotherapy alone or integrated), it is the ambition of the European School of Oncology to fill a cultural and scientific gap and, thereby, create a bridge between the University and Industry and between these two and daily medical practice. One of the more recent initiatives of ESO has been the institution of permanent study groups, also called task forces, where a limited number of leading experts are invited to meet once a year with the aim of defining the state of the art and possibly reaching a consensus on future developments in specific fields of oncology.
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Synthetic biology applications in industrial microbiology

Author: Weiwen Zhang,David Nielsen

Publisher: Frontiers E-books

ISBN: 288919342X

Category:

Page: N.A

View: 2635

Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology. As one emergent discipline, synthetic biology aims to design and engineer novel biologically-based parts, devices, and systems, in addition to redesigning existing, natural biological systems. Although previously relegated to demonstration studies, more recent research in synthetic biology has focused on the rational engineering of industrial microorganisms with the potential to address many of society’s critical challenges. Within the realm of industrial microbiology, progress in the field of synthetic biology has enabled the development of, for example, new biosynthetic pathways for the production of renewable fuels and chemicals, programmable logic controls to regulate and optimize cell function, and robust microbes for the destruction of harmful environmental contaminants. Some of the exciting examples included producing anti-malarial drug, anti- cancer taxol precursor and various biofuel molecules in E. coli and yeast. In addition, these researches have also greatly enhanced our understanding of the cellular machinery and its regulation in some of the industry important microbes, laying an important foundation for further design and engineering of biological function for even greater application. For these reasons, we present here a collection of articles from the leading edge of the field of synthetic biology, with a specific focus on the development in industrial microorganisms. It is the intent of this collection to reach a wide audience whose interests and expertise spans from development of novel synthetic biology methodologies and theories (both experimental and computational) to practical applications seeking to address issues facing the world today.
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Design and Retrofit of Wastewater Treatment Plants for Biological Nutritient Removal

Author: Clifford W. Randall,James Lang Barnard

Publisher: CRC Press

ISBN: 9780877629221

Category: Technology & Engineering

Page: 434

View: 2490

This book presents information that can be used for the design and operation of wastewater treatment plants that utilize biological nutrient removal processes, i.e., processes that utilize biological mechanisms instead of chemical mechanisms, to remove phosphorus and nitrogen from wastewaters. The book provides: basic fundamentals, concepts, and theories; design of prefermentation units, various types of BNR systems, and secondary clarifiers; retrofitting conventional activated sludge plants; modeling considerations; and special considerations for BNR systems. It includes full-scale and pilot plant case histories, design examples, and retrofit of existing plants.
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Chirality in Drug Design and Development

Author: Indra K. Reddy,Reza Mehvar

Publisher: CRC Press

ISBN: 0824751094

Category: Science

Page: 1200

View: 3700

Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design.
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Biosimilars

Design and Analysis of Follow-on Biologics

Author: Shein-Chung Chow

Publisher: CRC Press

ISBN: 1466579692

Category: Mathematics

Page: 444

View: 2764

As many biological products face losing their patents in the next decade, the pharmaceutical industry needs an abbreviated regulatory pathway for approval of biosimilar drug products, which are cost-effective, follow-on/subsequent versions of the innovator’s biologic products. But scientific challenges remain due to the complexity of both the manufacturing process and the structures of biosimilar products. Written by a top biostatistics researcher, Biosimilars: Design and Analysis of Follow-on Biologics is the first book entirely devoted to the statistical design and analysis of biosimilarity and interchangeability of biosimilar products. It includes comparability tests of important quality attributes at critical stages of the manufacturing processes of biologic products. Connecting the pharmaceutical/biotechnology industry, government regulatory agencies, and academia, this state-of-the-art book focuses on the scientific factors and practical issues related to the design and analysis of biosimilar studies. It covers most of the statistical questions encountered in various study designs at different stages of research and development of biological products.
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