Biomolecular Crystallography

Principles, Practice, and Application to Structural Biology

Author: Bernhard Rupp

Publisher: Garland Science

ISBN: 1134064195

Category: Science

Page: 800

View: 4238

Synthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography._ Deftly illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. It distills key concepts for understanding the practice and analysis of protein crystal structures and contains examples of biologically-relevant molecules, complexes, and drug target structures. Biomolecular Crystallography will be a valuable resource for advanced undergraduate and graduate students and practitioners in structural biology, crystallography, and structural bioinformatics.

Outline of Crystallography for Biologists

Author: David Blow

Publisher: Oxford University Press on Demand

ISBN: 0198510519

Category: Medical

Page: 236

View: 4877

X-ray crystallography is the main method used to determine the structure of biological molecules. X-ray crystallography is explained without maths and reading this text allows biologists to assess the quality and accuracy of biological structures.

Membrane Structural Biology

With Biochemical and Biophysical Foundations

Author: Mary Luckey

Publisher: Cambridge University Press

ISBN: 1107729335

Category: Science

Page: 400

View: 785

This textbook provides a strong foundation and a clear overview for students of membrane biology and an invaluable synthesis of cutting-edge research for working scientists. The text retains its clear and engaging style, providing a solid background in membrane biochemistry, while also incorporating the approaches of biophysics, genetics and cell biology to investigations of membrane structure, function and biogenesis to provide a unique overview of this fast-moving field. A wealth of new high resolution structures of membrane proteins are presented, including the Na/K pump and a receptor-G protein complex, offering exciting insights into how they function. All key tools of current membrane research are described, including detergents and model systems, bioinformatics, protein-folding methodology, crystallography and diffraction, and molecular modeling. This comprehensive and up-to-date text, emphasising the correlations between membrane research and human health, provides a solid foundation for all those working in this field.

Crystallography Made Crystal Clear

A Guide for Users of Macromolecular Models

Author: Gale Rhodes

Publisher: Academic Press

ISBN: 0323137784

Category: Science

Page: 202

View: 5234

Crystallography Made Crystal Clear is designed to meet the need for an X-ray analysis that is between brief textbook sections and complete treatments. The book provides non-crystallographers with an intellectually satisfying explanation of the principles of how protein models are gleaned from X-ray analysis. The understanding of these concepts will foster wise use of the models, including the recognition of the strengths and weaknesses of pictures or computer graphics. Since proteins comprise the majority of the mass of macromolecules in cells and carry out biologically important tasks, the book will be of interest to biologists. Provides accessible descriptions of principles of x-ray crystallography, built on simple foundations for anyone with a basic science background Leads the reader through clear, thorough, unintimidating explanations of the mathematics behind crystallography Explains how to read crystallography papers in research journals If you use computer-generated models of proteins or nucleic acids for: Studying molecular interactions Designing ligands, inhibitors, or drugs Engineering new protein functions Interpreting chemical, kinetic, thermodynamic, or spectroscopic data Studying protein folding Teaching macromolecule structure,and if you want to read new structure papers intelligently; become a wiser user of macromolecular models; and want to introduce undergraduates to the important subject of x-ray crystallography, then this book is for you.

Introduction to Protein Structure

Author: Carl-Ivar Brändén,John Tooze

Publisher: Taylor & Francis

ISBN: 0815323050

Category: Medical

Page: 410

View: 2238

This new edition gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context, illustrated in colour to illuminate the structural principles described in the text.

Biomolecular Crystallography, Principles, Practice, and Application to Structural Biology

Biology, Molecular biology

Author: CTI Reviews

Publisher: Cram101 Textbook Reviews

ISBN: 1467201219

Category: Education

Page: 47

View: 7974

Facts101 is your complete guide to Biomolecular Crystallography, Principles, Practice, and Application to Structural Biology. In this book, you will learn topics such as as those in your book plus much more. With key features such as key terms, people and places, Facts101 gives you all the information you need to prepare for your next exam. Our practice tests are specific to the textbook and we have designed tools to make the most of your limited study time.

Crystals, X-rays and Proteins

Comprehensive Protein Crystallography

Author: Dennis Sherwood,Jon Cooper

Publisher: Oxford University Press

ISBN: 019955904X

Category: Science

Page: 621

View: 7769

Update to: Crystals, X-rays, and proteins / Dennis Sherwood. 1976.


Molecular and Cell Biology

Author: Horst Feldmann

Publisher: John Wiley & Sons

ISBN: 3527659196

Category: Science

Page: 464

View: 1256

Finally, a stand-alone, all-inclusive textbook on yeast biology. Based on the feedback resulting from his highly successful monograph, Horst Feldmann has totally rewritten he contents to produce a comprehensive, student-friendly textbook on the topic. The scope has been widened, with almost double the content so as to include all aspects of yeast biology, from genetics via cell biology right up to biotechnology applications. The cell and molecular biology sections have been vastly expanded, while information on other yeast species has been added, with contributions from additional authors. Naturally, the illustrations are in full color throughout, and the book is backed by a complimentary website. The resulting textbook caters to the needs of an increasing number of students in biomedical research, cell and molecular biology, microbiology and biotechnology who end up using yeast as an important tool or model organism.

Studyguide for Biomolecular Crystallography

Principles, Practice, and Application to Structural Biology by Rupp, Bernhard

Author: Cram101 Textbook Reviews

Publisher: Cram101

ISBN: 9781478488330


Page: 242

View: 4515

Never HIGHLIGHT a Book Again Virtually all testable terms, concepts, persons, places, and events are included. Cram101 Textbook Outlines gives all of the outlines, highlights, notes for your textbook with optional online practice tests. Only Cram101 Outlines are Textbook Specific. Cram101 is NOT the Textbook. Accompanys: 9780521673761

Textbook of Structural Biology

Author: Anders Liljas

Publisher: World Scientific

ISBN: 9812772073

Category: Science

Page: 572

View: 2120

A textbook for undergraduate and graduate students in structural biology, chemistry, biochemistry, biology and medicine. It covers various aspects of proteins, nucleic acids and lipids, including the rise and fall of proteins, membranes and gradients, the structural biology of cells, and evolution - the comparative structural biology.

Structure in Protein Chemistry

Author: Jack Kyte

Publisher: Garland Science

ISBN: 1136843507

Category: Science

Page: 832

View: 6750

The second edition of Structure in Protein Chemistry showcases the latest developments and innovations in the field of protein structure analysis and prediction. The book begins by explaining how proteins are purified and describes methods for elucidating their sequences of amino acids and defining their posttranslational modifications. Comprehensive explanations of crystallography and of noncovalent forces-ionic interactions, hydrogen bonding, and the hydrophobic effect-act as a prelude to an exhaustive description of the atomic details of the structures of proteins. The resulting understanding of protein molecular structure forms the basis for discussions of the evolution of proteins, the symmetry of the oligomeric associations that produce them, and the chemical, mathematical, and physical basis of the techniques used to study their structures. The latter include image reconstruction, nuclear magnetic resonance spectroscopy, proton exchange, optical spectroscopy, electrophoresis, covalent cross-linking, chemical modification, immunochemistry, hydrodynamics, and the scattering of light, X-radiation, and neutrons. These procedures are applied to study the folding of polypeptides and the assembly of oligomers. Biological membranes and their proteins are also discussed. Structure in Protein Chemistry, Second Edition, bridges the gap between introductory biophysical chemistry courses and research literature. It serves as a comprehensive textbook for advanced undergraduates and graduate students in biochemistry, biophysics, and structural and molecular biology. Professionals engaged in chemical, biochemical, and molecular biological research will find it a useful reference.

Present at the Flood

How Structural Molecular Biology Came about

Author: Richard Earl Dickerson

Publisher: Sinauer Associates Incorporated

ISBN: 9780878931682

Category: Science

Page: 307

View: 6397

Present at the Flood tells the story of the rise of structural molecular biology-proteins and DNA-by immersing the reader in the original papers, written by the scientists who actually did the work. 187 pages from 42 essential scientific papers are reprinted, along with diagrams and commentaries to make them intelligible to the modern reader. The book achieves a personal note because the author was a worker in later years of the field and knew many of the key participants .

Fundamentals of Protein NMR Spectroscopy

Author: Gordon S. Rule,T. Kevin Hitchens

Publisher: Springer Science & Business Media

ISBN: 1402035004

Category: Science

Page: 532

View: 6940

NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs. This text not only covers topics from chemical shift assignment to protein structure refinement, as well as the analysis of protein dynamics and chemical kinetics, but also provides a practical guide to many aspects of modern spectrometer hardware, sample preparation, experimental set-up, and data processing. End of chapter exercises are included to emphasize important concepts. Fundamentals of Protein NMR Spectroscopy not only offer students a systematic, in-depth, understanding of modern NMR spectroscopy and its application to biomolecular systems, but will also be a useful reference for the experienced investigator.

Molecular Biology

Principles and Practice

Author: Michael M. Cox,Jennifer Doudna,Michael O'Donnell

Publisher: Macmillan Higher Education

ISBN: 131911637X

Category: Science

Page: 944

View: 9020

Written and illustrated with unsurpassed clarity, Molecular Biology: Principles and Practice introduces fundamental concepts while exposing students to how science is done. The authors convey the sense of joy and excitement that comes from scientific discovery, highlighting the work of researchers who have shaped—and who continue to shape—the field today. See what's in the LaunchPad


Author: Christian Bök

Publisher: Coach House Books

ISBN: 9781552451199

Category: Science

Page: 157

View: 4394

Crystallography is the mineral science whose name means 'lucid writing.' Long out of print, but now available again in an elegant revised edition, this extraordinary work of avant-garde literature explores the boundary between science and poetry, suggesting that to write with clarity in either discipline involves the most intense thought, much like an act of 'lucid dreaming.' The book reveals that, within the sediment of everyday language, poems are the crystalline formations. -- Back cover.

When the Scientist Presents

Author: Jean-Luc Lebrun

Publisher: World Scientific

ISBN: 9814338486

Category: Communication in science

Page: 264

View: 5198

Check out the author's website at This book looks at the presenting scientist from a novel angle: the presenter-host. When scientists give a talk, the audience (“guests”) expects the title of the talk to determine presentation content, they require understandable slides, and they demand visible and audible scientific authority. To each expectation corresponds a set of skills: personal (voice, host qualities, time control), technical (presentation tools and slide design), and scientific (Q&A, slide content). The author takes an original human factor view of the presentation delivery, in which the audience is easily distracted, rapidly forgetful, and increasingly impatient. Thus, insightful pointers are given on how to deliver the talk, how to craft the slides, and how to prevent the computer from rendering the presenting host-scientist into a “ghost”. In addition, the book goes in-depth over the treatment of questions by examining the motives and style of the questioners, and advising on how best to answer to each type of questioner. The book comes with a DVD for audio and video examples, and includes essential PowerPoint and Keynote techniques that a presenter cannot live without.Contents: "Content Selection: "Paper and Oral Presentation: The DifferenceContent Filtering Criteria"Audience Expectations: "General Audience ExpectationsScientific Audience Expectations"The Slides: "Five Slide Types, Five RolesSlide Design"The Presenter: "The Master of ToolsScientist and Perfect HostThe Grabbing VoiceThe Answerable Scientist Readership: Students, graduates, postgraduates, and professionals seeking help in improving their scientific presentation skills.

Crystal structure analysis

a primer

Author: Jenny Pickworth Glusker,Kenneth N. Trueblood

Publisher: N.A


Category: Science

Page: 269

View: 6800

This practical guide explains how and why the architecture of molecules can be determined by analysis of the diffraction patterns produced by X-ray crystallography. Thoroughly illustrated, it is intended for nonspecialists who want to understand the fundamentals of this widely used method ofstructure determination. The new second edition has been revised and expanded to take account of the many recent advances in the field.

Biomolecular Forms and Functions

A Celebration of 50 Years of the Ramachandran Map

Author: Manju Bansal,N. Srinivasan

Publisher: World Scientific

ISBN: 9814449148

Category: Biomolecules

Page: 502

View: 3442

This volume is primarily a compilation of contributed articles representing the impact and application of Ramachandran's work on conformation analysis of biopolymers, as well as recent advances in macromolecular structural biology, involving diverse experimental and computational approaches. This volume is being published to coincide with a conference on "Biomolecular Forms and Functions: A celebration of 50 years of the Ramachandran Map" being held at the Indian Institute of Science, Bangalore, in January 2013.

Protein Crystallography

Author: T. L. Blundell,L. N. Johnson

Publisher: Academic Pr


Category: Science

Page: 565

View: 2136


Macromolecular Crystallography

Author: Charles W. Carter, Jr.

Publisher: Elsevier

ISBN: 0080497098

Category: Science

Page: 368

View: 7597

Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Methodological methods in crystals * Methodological methods data analysis