Activation of Unreactive Bonds and Organic Synthesis

Author: Shinji Murai

Publisher: Springer

ISBN: 3540685251

Category: Science

Page: 267

View: 6840

In the last few years a large repetoire of methods for the activation of unreactive organic functionalities and for their use in organic synthesis has been developed. In this volume, areas ranging from the activation of C-H bonds to the chemical transformation of dinitrogen are authoritatively discussed by leading experts in the field. To activate means to be able to cleave otherwise inert chemical bonds. The cleavage and formation of chemical bonds is fundamental to organic synthesis; these new activation methodologies make hitherto infeasible reactions extremely easy and create new opportunities for innovative organic transformations, for both industry and academia. This is the first book that provides a thorough and timely coverage of both inorganic and organic synthetic aspects of bond activation, thus giving a broad overview of the field and allowing both inorganic and organic chemists ready access to the methodologies involved.
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Homogeneous Catalysis for Unreactive Bond Activation

Author: Zhang-Jie Shi

Publisher: John Wiley & Sons

ISBN: 1118788990

Category: Science

Page: 648

View: 3732

This book offers a comprehensive overview of different catalytic reactions applied to the activation of chemical bonds. Each of the seven chapters covers key C-X classes where carbon is combined with another element: chlorine, fluorine, nitrogen, sulfur, oxygen, hydrogen, and carbon. The first part of the book discusses homogeneous catalysis in the activation and transformation of C-Cl and C-F, highlighting their basic activation modes, cross-coupling, and intensive mechanisms. The second part of the book focuses on C-N, C-S, and C-O bonds, mentioning their catalytic pathways. Finally, C-H and C-C bonds, their activation, chemical transformations, and applicability are covered. Overall, the book presents methodologies that can be applied to the efficient synthesis of drug molecules and fine chemicals. Through their presentation, the authors show that synthetic chemistry can be done in greener ways that limit hazards and pollution.
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Fundamentals of Molecular Catalysis

Author: N.A

Publisher: Elsevier

ISBN: 9780080532134

Category: Technology & Engineering

Page: 536

View: 9002

Almost all contemporary organic synthesis involve transition metal complexes as catalysts or particular reagents. The aim of this book is to provide the reader with detailed accounts of elementary processes within molecular catalysis to allow its development and as an aid in designing novel catalytic systems. The book comprises authoritative reviews on elementary processes from experts working at the forefront of organometallic chemistry. · This is the first book that focuses on elementary processes in transition metal complexes for understanding catalytic mechanisms · Provides detailed description of elementary processes involved in catalytic cycles by experts in the field · Provides an overview of the mechanisms of various homogeneous catalyses
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Advances in Organometallic Chemistry

Author: Pedro J. Pérez

Publisher: Academic Press

ISBN: 0128155108

Category: Science

Page: 321

View: 2719

Advances in Organometallic Chemistry, Volume 70, contains authoritative review articles of worldwide known researchers in the field of organometallic chemistry. This longstanding serial is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. It is ideal for a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies and practical applications. Topics of note in this new release include Carbon Dioxide Electroreduction Catalyzed by Organometallic Complexes, Single-electron Elementary Steps in Homogeneous Organometallic Catalysis, Recent advances in catalytic hydrosilylation of carbonyl groups mediated by well-defined first-row late transition metals, and more. Contains contributions from leading authorities in the field of organometallic chemistry Covers topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more Informs and updates readers on the latest developments in the field Carefully edited to provide easy-to-read material
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Advances in Inorganic Chemistry

Inorganic Reaction Mechanisms

Author: Rudi van Eldik,Colin D. Hubbard

Publisher: Gulf Professional Publishing

ISBN: 9780120236541

Category: Science

Page: 490

View: 7115

The Advances in Inorganic Chemistry series presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry ranging from bio-inorganic to solid state studies. This acclaimed serial features reviews written by experts in the area and is an indispensable reference to advanced researchers. Each volume of Advances in Inorganic Chemistry contains an index, and each chapter is fully referenced. This, the 54th volume in the series continues this tradition providing comprehensive reviews by leading experts in the field with the focus on inorganic and bioinorganic reaction mechanisms. The latest volume in this highly successful series is dedicated to inorganic and bioinorganic reaction mechanisms Comprehensive reviews written by leading experts in the field
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Chemtracts

Author: N.A

Publisher: N.A

ISBN: N.A

Category: Chemistry, Organic

Page: N.A

View: 8704

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Late-metal C-H Bond Activation

Cyclopropane Functionalizations and Progress Toward the C-H [sigma]-bond Complex

Author: Mitchell Ryan Anstey

Publisher: N.A

ISBN: N.A

Category:

Page: 406

View: 3424

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Journal

Author: American Chemical Society

Publisher: N.A

ISBN: N.A

Category: Chemistry

Page: N.A

View: 9363

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Green Techniques for Organic Synthesis and Medicinal Chemistry

Author: Wei Zhang,Berkeley Cue

Publisher: John Wiley & Sons

ISBN: 0470711515

Category: Medical

Page: 742

View: 2866

Green chemistry is a new way of looking at organic synthesis and the design of drug molecules, offering important environmental and economic advantages over traditional synthetic processes. Pharmaceutical companies are increasingly turning to the principles of green chemistry in an effort to reduce waste, reduce costs and develop environmentally benign processes. Green Techniques for Organic Synthesis and Medicinal Chemistry presents an overview of the established and emerging techniques in green organic chemistry, highlighting their applications in medicinal chemistry. The book is divided into four parts: Introduction: Introduces the reader to the toxicology of organic chemicals,their environmental impact, and the concept of green chemistry. Green Catalysis: Covers a variety of green catalytic techniques including organocatalysis, supported catalysis, biocatalysis, fluorous catalysis, and catalytic direct C-H bond activation reactions. Green Synthetic Techniques: Presents a series of new techniques, assessing the green chemistry aspects and limitations (i.e. cost, equipment, expertise). Techniques include reactions in alternative solvents, atom economic multicomponent reactions, microwave and ultrasonic reactions, solid-supported synthesis, fluorous and ionic liquid-based recycling techniques, and flow reactors. Green Techniques in Pharmaceutical Industry: Covers applications of green chemistry concepts and special techniques for medicinal chemistry, including synthesis, analysis, separation, formulation, , and drug delivery. Process and business case studies are included to illustrate the applications in the pharmaceutical industry. Green Techniques for Organic Synthesis and Medicinal Chemistry is an essential resource on green chemistry technologies for academic researchers, R&D professionals and students working in organic chemistry and medicinal chemistry.
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Iridium Complexes in Organic Synthesis

Author: Luis A. Oro,Carmen Claver

Publisher: John Wiley & Sons

ISBN: 3527623086

Category: Science

Page: 424

View: 9418

Ranging from hydrogenation to hydroamination, cycloadditions and nanoparticles, this first handbook to comprehensively cover the topic of iridium in synthesis discusses the important advances in iridium-catalyzed reactions, namely the use of iridium complexes in enantioselective catalysis. A must for organic, complex and catalytic chemists, as well as those working with/on organometallics.
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Alkene Metathesis in Organic Synthesis

Author: Alois Fürstner

Publisher: Springer Verlag

ISBN: N.A

Category: Science

Page: 231

View: 346

The tremendous progress in olefin metathesis achieved during the last decade can hardly be overestimated. Due to the development of a new generation of well defined and high-performance organometallic catalysts, this reaction is rapidly evolving into one of the most versatile tools for advanced organic chemistry, natural product synthesis, fine chemical production and polymer sciences. Written by some of the leading experts in this field, this monograph intends to familiarize the reader with the most exciting developments and frontiers in this flourishing field of chemistry research.
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Ruthenium in Organic Synthesis

Author: Shun-Ichi Murahashi

Publisher: John Wiley & Sons

ISBN: 3527605797

Category: Science

Page: 398

View: 4098

In this comprehensive book, one of the leading experts, Shun-Ichi Murahashi, presents all the important facets of modern synthetic chemistry using Ruthenium, ranging from hydrogenation to metathesis. In 14 contributions, written by an international authorship, readers will find all the information they need about this fascinating and extraordinary chemistry. The result is a high quality information source and a indispensable reading for everyone working in organometallic chemistry. From the contents: Introduction (S.-I. Murahashi) Hydrogenation and Transfer Hydrogenation (M. Kitamura and R. Noyori) Oxidations (S.-I. Murahashi and N. Komiya) Carbon-Carbon Bond Formations via Ruthenacycle Intermediates (K. Itoh) Carbon-Carbon Bond Formation via pi-Allylruthenium Intermediates (T. Mitsudo) Olefin Metathesis (R. H. Grubbs) Cyclopropanation (H. Nishiyama) Nucleophilic Addition to Alkynes and Reactions via Vinylidene Intermediates (P. Dixneuf) Reactions via C-H Activation (N. Chatani) Lewis Acid Reactions (E. P. Kundig) Reactions with CO and CO2 (T. Mitsudo) Isomerization of Organic Substrates Catalyzed by Ruthenium Complexes (H. Suzuki) Radical Reactions (H. Nagashima) Bond Cleavage Reactions (S. Komiya)
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Activating Unreactive Substrates

The Role of Secondary Interactions

Author: Carsten Bolm,F. Ekkehardt Hahn

Publisher: John Wiley & Sons

ISBN: 3527318232

Category: Science

Page: 481

View: 1686

The use of secondary interactions for the activation of non-reactive substrates constitutes a new and modern approach in catalysis. This first comprehensive treatment of this important research field covers the entire field and reveals the links between the various chemical disciplines. It thus adopts an interdisciplinary approach, making it of interest to the whole chemical community. A must for organic, inorganic, catalytic and complex chemists, as well as those working with/on organometallics.
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